Felis catus (domestic cat): 493669
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Entry
493669 CDS
T02385
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor precursor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca04010
MAPK signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04020
Calcium signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04360
Axon guidance
fca04510
Focal adhesion
fca04520
Adherens junction
fca05100
Bacterial invasion of epithelial cells
fca05144
Malaria
fca05200
Pathways in cancer
fca05202
Transcriptional misregulation in cancer
fca05205
Proteoglycans in cancer
fca05206
MicroRNAs in cancer
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05211
Renal cell carcinoma
fca05218
Melanoma
fca05223
Non-small cell lung cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
fca05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
493669 (MET)
04014 Ras signaling pathway
493669 (MET)
04015 Rap1 signaling pathway
493669 (MET)
04020 Calcium signaling pathway
493669 (MET)
04151 PI3K-Akt signaling pathway
493669 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
493669 (MET)
04520 Adherens junction
493669 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
493669 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
493669 (MET)
05202 Transcriptional misregulation in cancer
493669 (MET)
05206 MicroRNAs in cancer
493669 (MET)
05205 Proteoglycans in cancer
493669 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
493669 (MET)
05230 Central carbon metabolism in cancer
493669 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
493669 (MET)
05226 Gastric cancer
493669 (MET)
05218 Melanoma
493669 (MET)
05211 Renal cell carcinoma
493669 (MET)
05223 Non-small cell lung cancer
493669 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
493669 (MET)
09174 Infectious disease: parasitic
05144 Malaria
493669 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
493669 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
493669 (MET)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
493669 (MET)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
MET family
493669 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
TIG
Sema
PSI
Pkinase_fungal
Kinase-like
Linker_histone
Ninjurin
Motif
Other DBs
NCBI-GeneID:
493669
NCBI-ProteinID:
NP_001162167
Ensembl:
ENSFCAG00000009534
UniProt:
A0M8S8
LinkDB
All DBs
Position
A2:136661904..136780627
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AA seq
1382 aa
AA seq
DB search
MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSA
LGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSSEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLK
KTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVI
TSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTE
FPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISV
HETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPND
LLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagctacggggagtgcagagaggcactagtaaagtctgagatgaatgtgaacatgaag
tatcagcttcccaacttcactgcagaaacacccatccagaatgttgttttacacaagcat
catatttaccttggtgcagttaactatatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcccgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctcta
cttattgacacgtactatgacgaccaactcattagctgtggcagtgtccacagagggacc
tgccagcgacatgtccttccacccagcaatactgctgacatactgtcaaaagttcattgc
atgtactccccacaggcagacgaagagtccagccactgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgatatctgaaaagggccggttcatcaacttcttcgtgggcaat
accataaattcctcttacctaacagatcattcattgcattcaatatcagtgagaaggcta
aaggaaactcaagatggctttaagtttttaacagaccagtcttatattgatgttctccct
gaattcagagattcctaccctattaaatacatccatgcctttgaaagcaaccgttttatt
tactttttgacagtccagcgagaaactctagatgctcagacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcctacatggaaatgcctctggaatgtatc
ctcacagaaaagagaagaaagagatccacaagggaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggcccaccttgctaagcaaataggtgccaacctgaatgat
gacattctctatggagtattcgcacaaagcaagccggattctgctgaaccaatgaatcgc
tctgccgtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagattgtaaac
aaaaacaacgtgagatgtcttcaacatttttatggacccaaccacgaacactgctttaat
aggacacttttgagaaattcatcaggctgtgaagtgcgcagtgatgaatatcgaacggag
tttaccacagctttgcagcgagttgacttattcatgggccaattcaaccaagtcctctta
acatctatatccaccttcattaaaggagacctcaccattgctaatcttgggacatcagag
ggtcgctttatgcaggttgtggtttctcgatcaggatcatcaacacctcatgtgaatttt
cgcctggattcccaccctgtgtcttcagaagcaattgtggagcacccattaaaccaaaat
ggctacacactggttgttactggaaagaagatcaccaagatcccactgaatggcttaggc
tgtgaacatttccagtcctgcagtcagtgtctttctgcccctccctttgtgcagtgtggc
tggtgccacgataaatgtgtgcaactggaggaatgccccagtggaacatggactcaagag
atctgtctgcctacaatctatgaggttttcccaaccagtgcacccctggaaggaggaacg
atgctcactgtgtgtggctgggactttggattcaggaggaataataaatttgatttaaag
aaaactagagttttccttggaaatgagagctgcactttgaccttaagtgagagcacaaca
aatatgttgaaatgcacagttggtcctgcagtgaatgagcatttcaatatatccataatt
atttcaaatgggcgagggacagcacaatacagtacattttcctatgtggatcctgtaata
acaagtatttttccaagttatggtcctaagaccggtggcaccttgcttactttaactgga
aagtaccttaacagtgggaattctagacacatttcaattggtggaaaaacgtgtacttta
aaaagtgtgtcagatagtattctcgaatgttataccccagctcaaaccattccaactgag
tttcctattaaattgaaaattgacttagccaaccgagagatgaacagtttcagttaccag
gaagaccccattgtctatgcaattcatccaaccaaatcttttattagtggtgggagcacc
ataacagctgttgggaaaaacctgaattcagttagtgtcctaaggatggtaataagtgta
catgaaacaagaaggaactttacagtggcatgtcaccatcgctctaattcagagataatc
tgctgtacaactccttcactgcaacagctgaatctgcaactccctctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagactatatactcagattctgaagctgttttatgcaaggtccccaatgac
ctgctgaaattgaacaacgagctaaatatagagtggaagcaagcagtttcttcaaccatc
cttggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttatc
tcaatatcaataatactcttactattacttggggttttcctgtggctgaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaactcatctcagaatgga
tcatgcagacaagtacagtatcctctgacggacctgtcccccatgcttaatagtggggac
tctgatatatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagtccagcacgtagtgattgggccaagtagcctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtgtaccatgggactttattggac
agcgatgacaagaagattcactgtgctgtgaaatccttgaatagaatcactgacataggt
gaagtttcccagtttctgactgagggaatcatcatgaaagattttagtcatccaaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatat
atgaaacatggagatcttcgaaatttcatcagaaatgagactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtacacagagacttggctgctagaaactgtatgttggatgaaaaattcactgtcaag
gttgctgattttggtctggccagagacatgtatgataaagaatactacagtgtacacaac
aaaacgggcgccaagctgccagtgaagtggatggctctagaaagtctacaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggtgtgctcctctgggaactgatgacaaga
ggggctccaccttatcctgatgtcaacacctttgatataacagtttacttattgcaaggc
agaagactcttacagcccgaatactgcccagatcccttatatgaagtgatgctaaaatgc
tggcaccctaaagctgaactgcgcccatctttttctgaactggtctccaggatatcagcg
atattctctactttcattggggagcactatgtccatgtgaacgctacttatgtgaatgtc
aaatgtgttgctccatacccttctctgttgtcatcacaagataacattgatggcgagggg
gacacatga
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integrated database retrieval system
