| Entry |
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| Symbol |
MET
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| Name |
(RefSeq) hepatocyte growth factor receptor precursor
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| KO |
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| Organism |
fca Felis catus (domestic cat)
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| Pathway |
| fca01521 | EGFR tyrosine kinase inhibitor resistance |
| fca05100 | Bacterial invasion of epithelial cells |
| fca05202 | Transcriptional misregulation in cancer |
| fca05208 | Chemical carcinogenesis - reactive oxygen species |
| fca05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:fca00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
493669 (MET)
04014 Ras signaling pathway
493669 (MET)
04015 Rap1 signaling pathway
493669 (MET)
04020 Calcium signaling pathway
493669 (MET)
04151 PI3K-Akt signaling pathway
493669 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
493669 (MET)
04520 Adherens junction
493669 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
493669 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
493669 (MET)
05202 Transcriptional misregulation in cancer
493669 (MET)
05206 MicroRNAs in cancer
493669 (MET)
05205 Proteoglycans in cancer
493669 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
493669 (MET)
05230 Central carbon metabolism in cancer
493669 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
493669 (MET)
05226 Gastric cancer
493669 (MET)
05218 Melanoma
493669 (MET)
05211 Renal cell carcinoma
493669 (MET)
05223 Non-small cell lung cancer
493669 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
493669 (MET)
09174 Infectious disease: parasitic
05144 Malaria
493669 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
493669 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:fca01001]
493669 (MET)
Enzymes [BR:fca01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
493669 (MET)
Protein kinases [BR:fca01001]
Receptor tyrosine kinases (RTK)
MET family
493669 (MET)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
A2:134955518..135081533
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| AA seq |
1382 aa
MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSA
LGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSSEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLK
KTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVI
TSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTE
FPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISV
HETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPND
LLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEG
DT |
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| NT seq |
4149 nt +upstreamnt +downstreamnt
atgaaggcccctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagctacggggagtgcagagaggcactagtaaagtctgagatgaatgtgaacatgaag
tatcagcttcccaacttcactgcagaaacacccatccagaatgttgttttacacaagcat
catatttaccttggtgcagttaactatatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcccgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctcta
cttattgacacgtactatgacgaccaactcattagctgtggcagtgtccacagagggacc
tgccagcgacatgtccttccacccagcaatactgctgacatactgtcaaaagttcattgc
atgtactccccacaggcagacgaagagtccagccactgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgatatctgaaaagggccggttcatcaacttcttcgtgggcaat
accataaattcctcttacctaacagatcattcattgcattcaatatcagtgagaaggcta
aaggaaactcaagatggctttaagtttttaacagaccagtcttatattgatgttctccct
gaattcagagattcctaccctattaaatacatccatgcctttgaaagcaaccgttttatt
tactttttgacagtccagcgagaaactctagatgctcagacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcctacatggaaatgcctctggaatgtatc
ctcacagaaaagagaagaaagagatccacaagggaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggcccaccttgctaagcaaataggtgccaacctgaatgat
gacattctctatggagtattcgcacaaagcaagccggattctgctgaaccaatgaatcgc
tctgccgtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagattgtaaac
aaaaacaacgtgagatgtcttcaacatttttatggacccaaccacgaacactgctttaat
aggacacttttgagaaattcatcaggctgtgaagtgcgcagtgatgaatatcgaacggag
tttaccacagctttgcagcgagttgacttattcatgggccaattcaaccaagtcctctta
acatctatatccaccttcattaaaggagacctcaccattgctaatcttgggacatcagag
ggtcgctttatgcaggttgtggtttctcgatcaggatcatcaacacctcatgtgaatttt
cgcctggattcccaccctgtgtcttcagaagcaattgtggagcacccattaaaccaaaat
ggctacacactggttgttactggaaagaagatcaccaagatcccactgaatggcttaggc
tgtgaacatttccagtcctgcagtcagtgtctttctgcccctccctttgtgcagtgtggc
tggtgccacgataaatgtgtgcaactggaggaatgccccagtggaacatggactcaagag
atctgtctgcctacaatctatgaggttttcccaaccagtgcacccctggaaggaggaacg
atgctcactgtgtgtggctgggactttggattcaggaggaataataaatttgatttaaag
aaaactagagttttccttggaaatgagagctgcactttgaccttaagtgagagcacaaca
aatatgttgaaatgcacagttggtcctgcagtgaatgagcatttcaatatatccataatt
atttcaaatgggcgagggacagcacaatacagtacattttcctatgtggatcctgtaata
acaagtatttttccaagttatggtcctaagaccggtggcaccttgcttactttaactgga
aagtaccttaacagtgggaattctagacacatttcaattggtggaaaaacgtgtacttta
aaaagtgtgtcagatagtattctcgaatgttataccccagctcaaaccattccaactgag
tttcctattaaattgaaaattgacttagccaaccgagagatgaacagtttcagttaccag
gaagaccccattgtctatgcaattcatccaaccaaatcttttattagtggtgggagcacc
ataacagctgttgggaaaaacctgaattcagttagtgtcctaaggatggtaataagtgta
catgaaacaagaaggaactttacagtggcatgtcaccatcgctctaattcagagataatc
tgctgtacaactccttcactgcaacagctgaatctgcaactccctctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagactatatactcagattctgaagctgttttatgcaaggtccccaatgac
ctgctgaaattgaacaacgagctaaatatagagtggaagcaagcagtttcttcaaccatc
cttggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttatc
tcaatatcaataatactcttactattacttggggttttcctgtggctgaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaactcatctcagaatgga
tcatgcagacaagtacagtatcctctgacggacctgtcccccatgcttaatagtggggac
tctgatatatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagtccagcacgtagtgattgggccaagtagcctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtgtaccatgggactttattggac
agcgatgacaagaagattcactgtgctgtgaaatccttgaatagaatcactgacataggt
gaagtttcccagtttctgactgagggaatcatcatgaaagattttagtcatccaaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatat
atgaaacatggagatcttcgaaatttcatcagaaatgagactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtacacagagacttggctgctagaaactgtatgttggatgaaaaattcactgtcaag
gttgctgattttggtctggccagagacatgtatgataaagaatactacagtgtacacaac
aaaacgggcgccaagctgccagtgaagtggatggctctagaaagtctacaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggtgtgctcctctgggaactgatgacaaga
ggggctccaccttatcctgatgtcaacacctttgatataacagtttacttattgcaaggc
agaagactcttacagcccgaatactgcccagatcccttatatgaagtgatgctaaaatgc
tggcaccctaaagctgaactgcgcccatctttttctgaactggtctccaggatatcagcg
atattctctactttcattggggagcactatgtccatgtgaacgctacttatgtgaatgtc
aaatgtgttgctccatacccttctctgttgtcatcacaagataacattgatggcgagggg
gacacatga |
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