Felis catus (domestic cat): 493691
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Entry
493691 CDS
T02385
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04020
Calcium signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04148
Efferocytosis
fca04260
Cardiac muscle contraction
fca04261
Adrenergic signaling in cardiomyocytes
fca04380
Osteoclast differentiation
fca04919
Thyroid hormone signaling pathway
fca04972
Pancreatic secretion
fca05010
Alzheimer disease
fca05017
Spinocerebellar ataxia
fca05022
Pathways of neurodegeneration - multiple diseases
fca05410
Hypertrophic cardiomyopathy
fca05412
Arrhythmogenic right ventricular cardiomyopathy
fca05414
Dilated cardiomyopathy
fca05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
493691 (ATP2A2)
04024 cAMP signaling pathway
493691 (ATP2A2)
04022 cGMP-PKG signaling pathway
493691 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
493691 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
493691 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
493691 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
493691 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
493691 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
493691 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
493691 (ATP2A2)
05017 Spinocerebellar ataxia
493691 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
493691 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
493691 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
493691 (ATP2A2)
05414 Dilated cardiomyopathy
493691 (ATP2A2)
05415 Diabetic cardiomyopathy
493691 (ATP2A2)
Enzymes [BR:
fca01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
493691 (ATP2A2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
493691
NCBI-ProteinID:
NP_001009216
UniProt:
Q00779
LinkDB
All DBs
Position
D3:8390362..8449116
Genome browser
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGYFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYKKFGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggctacttcggcgtcaacgag
agcacagggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgttggaacttgtgattgagcagtttgaagactta
ttagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgctattgtgggtgtatggcaggaaagaaatgctgagaatgctattgaagcccttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaggacatagttcctggcgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctgagagttgaccagtccattctc
acaggtgagtctgtgtctgtcatcaagcacactgaccctgtcccagacccacgggccgtc
aaccaagataagaagaacatgctgttttctggaacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagttaacacagaaatcggcaagatccgggatgagatggtg
gcaacagaacaggagagaacacccctccagcagaaactagacgagtttggggagcagctt
tccaaagtcatatcccttatttgcattgcagtctggatcataaacattgggcacttcaat
gacccagttcacggaggctcctggatcaggggtgctatttactactttaaaattgcggtg
gccctggctgtggcggccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagtctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacgcttacgacgaaccag
atgtcagtgtgcaggatgttcattctggacaaggttgagggggatacttgttcccttaat
gagtttaccataactgggtcaacatatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcattggattacaatgaggcgaagggcgtgtataaaaagtttggggaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaaagagcaaatgcctgcaactcggtcataaagcagttaatgaaa
aaagaatttactctcgagttttcacgcgatagaaaatcaatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggcgctcccgaaggtgtc
attgacaggtgcacccacattcgggttggaagtaccaaagtccctatgacccctggagtc
aaacagaaggtcatgtctgtcatcagggaatggggtagtggcagcgacacactgcggtgc
ctggctctggccactcatgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttatcaaatatgagactaatctgactttcgttggctgtgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctttgccggcaagcaggcatccgggtg
atcatgatcacaggggacaacaaaggcactgctgtggccatctgtcgccgcattggcatc
tttgggcaggacgaggatgtgacgtcaaaggcttttacgggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgcttgaatgcccgctgttttgctcgagttgagcct
tcccacaagtcaaaaattgtagagtttcttcagtcttttgatgagattacagctatgacc
ggggatggcgtgaatgatgctcccgccctgaagaaatctgagattggcattgccatgggc
tctggcacggcagtggctaaaaccgcctctgagatggtcctggccgacgacaacttctcc
accattgtggctgctgttgaggaggggcgggcgatttacaacaatatgaagcagtttatc
cgctacctcatctcttcgaatgtgggggaagttgtctgtattttcctgactgcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccaccgcactggggtttaacccacctgatctggacatcatgaacaaaccaccc
cggaacccgaaggaaccactgatcagcggatggctctttttccgttacctagctattggc
tgttacgttggcgctgctactgtgggtgctgccgcgtggtggtttattgctgccgacggg
ggtccaagggtgtccttctaccaactgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccgtacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtct
ctgctgaggatgcccccttgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccatttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaacttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggat
gagacactcaagtttgtggcccgcaactacctggaacctgcaatactggagtaa
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