Felis catus (domestic cat): 493693
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Entry
493693 CDS
T02385
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
KO
K12385
Niemann-Pick C1 protein
Organism
fca
Felis catus (domestic cat)
Pathway
fca03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
fca04142
Lysosome
fca04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
493693 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
493693 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
493693 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
fca02000
]
493693 (NPC1)
Transporters [BR:
fca02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
493693 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
493693
NCBI-ProteinID:
NP_001009829
UniProt:
Q9N0Q0
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All DBs
Position
D3:complement(46053183..46107852)
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AA seq
1276 aa
AA seq
DB search
MTARGPALGLLLLLLCPAQVLAQSCIWYGECGIASGDKRYNCKYSGPPKPLPKDGYDLVQ
ELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQF
LNVTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKD
AEACNATNWIEYMFSKDNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSC
QDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRYFVS
EYTPIDSNIAFSVNANDRGEASCCDALGAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAF
IAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTY
QPYPSGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCT
ILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVKNYKNPNLT
ISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAG
ILIVLSSKACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETL
DQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFV
SLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRLFKHSYSPLLLKDWMRPIVIA
IFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSLKYLHAGPPVYFVLEEGHDYTS
LKGQNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRVYN
STDRFCNASVVDPACIRCRPLTQEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSS
AVNILGNDTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMGLEGSNYRVFPYS
VFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVM
WLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSVFSGI
TLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSINKAKSLA
TQEQYKGTEREQLLNF
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgcgcggcccagccctcggcctccttctgctgctgctgtgtcccgcgcaggtg
ttggcacagtcttgcatctggtatggagagtgtggaattgcatctggagataagaggtac
aactgcaaatattcagggccaccaaaacccttgccgaaggatgggtatgacttagtgcag
gagctctgtccaggattcttctttgacaatgtcagtctttgttgcgatgtgcagcagctc
cagacactgaaagacaacctgcagctgcctctacagtttctgtccagatgtccatcctgt
ttctataacctagtgaacctgttttgcgagctgacgtgtagccctcggcaaagtcagttt
ctgaatgttacagcaactgaagattatgttgatcctgttacaaaccagactaaaacaaat
gtaaaagaattacagtactacattggagagagttttgccaatgccatgtacaatgcctgc
cgggacgtggaggccccctccagtaatgacaaagccctgggactgctgtgtgggaaggac
gccgaagcctgcaatgccactaactggattgagtacatgttcagtaaggacaacggccag
gcacctttcaccatcacacccattttttcagatcttccaacccatgggatggagcccatg
aacaatgccaccaagggctgtgacgagtctgtggacgaggtcaccgggccgtgcagctgc
caggactgctcaattgtttgtggcccaaagccccagcccccaccgcctcctgtgccctgg
agaatcttgggcctggacgccatgtatgtcatcatgtggatcacctacatggcatttttg
cttgtgttttttggagctttttttgctttgtggtgctacagaaaacgctattttgtctcc
gagtacacccccattgatagcaacatagctttctctgtaaatgccaatgacagaggggag
gcgtcctgctgcgacgcgcttggtgcggcatttgagggctgtctgaggcggctcttctca
cagtggggctctttctgcgtccgaaacccgggccccatcatcttcttctccctggccttc
attgccgcctgttcttcaggcctggtgtttgtgcgggtcacgaccaatccagttgacctg
tggtcagctcccagcagccaggcgcgcctcgagaaagagtactttgacacgcactttggg
cctttcttccgcacggagcagctcatcatccaggccccccacaccagtgcacacacttac
cagccgtacccctcaggatccgatgtgcccttcggacctccgcttgacctcgcgatcttg
caccaggttcttgacttacaaactgccatcgaaaatatcactgcatcttataacaatgag
accgtgacacttcaagacatctgcgtggcccccctgtcaccctataacaagaactgcacc
attctgagcgtgttaaattacttccagaacagccattccatgctggaccatgaaatagga
gatgacttctttgtgtatgcagattaccacacgcacttgctatactgtgtacgggctcct
gcctctctgaacgataccagtttgctccatgatccttgcctgggtacattcggtgggcca
gtgttcccgtggcttgtgttaggaggctatgatgatcaaaattacaataatgccacagcc
cttgtgattacctttcctgtcaataattactataatgatacagagaggctccagaaggcc
cacgtctgggaaaaagagtttattaattttgtgaaaaactacaagaatccaaatctgacc
atttctttcactactgagcgaagtattgaagatgaactaaatcgtgaaagtaacggtgat
attttcactgttataatcagctatgccatcatgtttctgtacatttccatagccttgggg
cacatcaaaagctgtagcaggcttctagtggactctaaaatctccctcggcatcgcgggg
atcctcattgtgttgagctcaaaggcgtgctcgttgggcatctttagttacgttgggatc
cccctcaccctcattgtgatcgaagtcatcccattcctggtgctggctgttggggtggac
aacatcttcattctggtccagacctaccagcgagatgaacgtcttcatggagaaactctg
gatcagcagctgggcagggtcctaggagaagtggctcctagtatgttcctgtcatccttt
tcagaggctgtagcatttttcttaggagcgctgtcaaagatgccggctgttcacaccttc
tctctgtttgccgggatggcagtcctcatcgacttccttcttcagattacctgtttcgtg
agtctcttggggttagacattaagcgtcaagagaaaaaccgtctggatgttctttgctgt
gtcagaggctctgaagatggaaccagtgtccaggcttcagagagctgcttgtttcggctc
ttcaagcactcctattctccacttctgcttaaggactggatgagaccaattgtgatagca
atatttgtgggtgtcctgtcattcagtgttgcagtcctgaacaaagtggaaatcggattg
gatcagtctctttcaatgccagatgactcctacgtgatggattatttcaagtccctcaaa
tacctgcatgcaggtccacctgtgtactttgtcctggaggaagggcatgactacacctct
ctgaaagggcagaacatggtgtgcggaggcatgggctgcaataacgactccctggtgcag
cagatattcaacgcggcccagctagacagctatacccgaataggctttgctccctcttcc
tggatcgacgattactttgattgggtcaagcctcagtcttcttgctgtagagtctacaac
agcaccgatcggttctgcaatgcttcagtggttgaccctgcctgcatccgctgcaggccc
ctcacccaggagggcaaacagaggcctcaaggtggagacttcatgagattcctgcccatg
ttcctttctgataacccgaaccccaagtgcggcaaagggggacatgctgcttacagttcg
gcagttaacatcctcggcaatgacacgggtgtcggagccacttacttcatgacctaccac
accgtgcttcagacgtctgctgactttactgacgccatgagaaaagccaacctcatcgcc
agtaacatcaccaaaaccatgggccttgaaggaagtaattaccgtgtgttcccatacagt
gtgttctatgtcttctacgaacagtacctgaccattattgatgacacgatctttaacctc
agcgtgtccctgggagccatcttcttagtgaccgtgattctcctgggctgtgatctgtgg
tctgcagtgatcatgtgtatcaccatcgctatgatcttggtcaacatgtttggcgtcatg
tggctgtggggcatcagtctgaatgcagtttccttggtcaacttggttatgagctgtggc
atttccgtggagttctgcagccacataacgagagcattcacagtgagcatgaagggcagc
cgtgcacaacgggcagaagaggcgctcgctcacatgggcagttctgtgttcagtggaatc
acactaacaaaatttggagggattgtggtattggcctttgccaaatctcagattttccag
atattttacttcaggatgtatttggctatggtcttactgggagccacccacggcttgatc
ttcctcccggtcttactcagctacataggcccatcaataaataaagccaaaagcttggcc
actcaagagcaatacaaaggtacagagcgagaacaactcctaaatttctag
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