Felis catus (domestic cat): 654399
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Entry
654399 CDS
T02385
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
fca
Felis catus (domestic cat)
Pathway
fca04010
MAPK signaling pathway
fca04020
Calcium signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04260
Cardiac muscle contraction
fca04261
Adrenergic signaling in cardiomyocytes
fca04270
Vascular smooth muscle contraction
fca04723
Retrograde endocannabinoid signaling
fca04725
Cholinergic synapse
fca04726
Serotonergic synapse
fca04727
GABAergic synapse
fca04911
Insulin secretion
fca04912
GnRH signaling pathway
fca04921
Oxytocin signaling pathway
fca04924
Renin secretion
fca04925
Aldosterone synthesis and secretion
fca04927
Cortisol synthesis and secretion
fca04929
GnRH secretion
fca04934
Cushing syndrome
fca04935
Growth hormone synthesis, secretion and action
fca05010
Alzheimer disease
fca05020
Prion disease
fca05022
Pathways of neurodegeneration - multiple diseases
fca05207
Chemical carcinogenesis - receptor activation
fca05410
Hypertrophic cardiomyopathy
fca05412
Arrhythmogenic right ventricular cardiomyopathy
fca05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
654399 (CACNA1S)
04020 Calcium signaling pathway
654399 (CACNA1S)
04024 cAMP signaling pathway
654399 (CACNA1S)
04022 cGMP-PKG signaling pathway
654399 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
654399 (CACNA1S)
04929 GnRH secretion
654399 (CACNA1S)
04912 GnRH signaling pathway
654399 (CACNA1S)
04921 Oxytocin signaling pathway
654399 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
654399 (CACNA1S)
04924 Renin secretion
654399 (CACNA1S)
04925 Aldosterone synthesis and secretion
654399 (CACNA1S)
04927 Cortisol synthesis and secretion
654399 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
654399 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
654399 (CACNA1S)
04270 Vascular smooth muscle contraction
654399 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
654399 (CACNA1S)
04725 Cholinergic synapse
654399 (CACNA1S)
04726 Serotonergic synapse
654399 (CACNA1S)
04723 Retrograde endocannabinoid signaling
654399 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
654399 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
654399 (CACNA1S)
05020 Prion disease
654399 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
654399 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
654399 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
654399 (CACNA1S)
05414 Dilated cardiomyopathy
654399 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
654399 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
fca04040
]
654399 (CACNA1S)
Ion channels [BR:
fca04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
654399 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
654399
NCBI-ProteinID:
NP_001033694
UniProt:
Q2QCM6
LinkDB
All DBs
Position
F1:complement(39687082..39752552)
Genome browser
AA seq
1871 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVTIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFAVEML
LKMCGLGLRQYFMSIFNRFDCFVVCSGVLELLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRMLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFKCS
TSEALQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFVSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVACDNSSHSNSQL
FSSIRYEREFPGETETPAARGGAFGQPRSVLGAHSKSCVEKLKGQLAQREMPGAQASPTP
CQRADAEPPLPGERRDPTPGPEEASHHGRTKESSSRCQTPATARLIQEALVRGGLDTLAA
DADFVTVTGRALADACQMEPEDVEVAATELLKRQESPEGMASAQGRLSLGSSLGSLDQHQ
GSQETLIPRRL
NT seq
5616 nt
NT seq
+upstream
nt +downstream
nt
atggagccatcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctcaaccttggtctggagaaactggagtatttcttcctcatcgtcttctcaatcgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaatgtgctagacttcatcatcgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacaccgccccgatgagcagcaaaggggctggcctggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggcttgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgctcgtcctctttatggtcaccatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacggtagagaacgag
aagccctcaccctgcgccaggacgggctcgggacgcccgtgcaccatcaacggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacgcactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
gggtccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggaa
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctctggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagtttgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggttg
acccatttgcaagacgttgccaaccgagtgctgctggccctcttcgccgtcgagatgctg
ctgaagatgtgcgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcgtcctggagctgctgctggtggagtcaggtgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctcctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgcttttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaattctgtgatg
tacaacgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaactatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagctgaggag
agaaaacgcaggaagatgtccaagggtcttccagataagtcagaggaagagaagtcagta
atggccaagaagctggaacagaaacccaagggtgaaggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggagatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgcccg
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagctccttcttc
attttcagccccaccaacaagatccgtgtcttgtgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatccttcttttcatcctgctcagcagtgccgcactggccgcagaggac
cccatccgggccgagtccgtgaggaatcagatccttgggtatttcgacattgcgttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactatttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctctgtggtgaaaatcctgaggatgctgagg
gtgctccggcccctgcgggccatcaacagagcaaaggggctgaagcacgtggtgcagtgt
gtgtttgtggccatccgcaccatcgggaacatcgtcctcgtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaagggcaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acccagatggagctgcgcccccgccagtggatacacagcgacttccatttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctgctt
taccaggccatagactcatacaaggaagacacaggccccgtctacaacaaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaactgtgaa
ctggacaagaaccagcgccagtgtgtgcaatatgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtatgtcgtcacctcctcctacttt
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgatgtcattctcagt
gaaatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccggatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcactctgctgtggacgttc
atcaagtccttccaggccctgccatacgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgttgctgctcttcaagtgttcc
acaagtgaagccttgcaggagatcctcctggcctgcagctacggcaagttgtgtgacccc
gaatcggattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactattac
ttcgtcagcttctacatgctctgcgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactacctcacccgggactggtccatcctgggcccccatcacctggat
gagttcaaagccatttgggcagagtatgacccggaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagacggatccaaccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagcgacggcacg
gtcaccttcaacgccactctcttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcttggatcaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactgtacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaagagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actgggggcctgtttggccaggtggacaacttcatggaaaggaccaactccctgccccct
gtgatggccaaccagagacccctccagtttgctgagatagagatggaagagctggaatca
cctgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaac
accaataatgccaatgccaatgttgcctgtgacaacagcagccacagcaacagccagcta
ttttccagcatccgctatgaaagggagttccctggagagacagagacgcctgctgccaga
ggaggagcctttggccagccccgaagcgtcctgggagcccacagcaaatcctgtgtggaa
aagctaaaaggacagctggcccagagagaaatgcccggggcccaggcgtctcctaccccc
tgccagcgtgccgacgcagagcctcccctgcctggggagaggagggaccccaccccgggg
cctgaggaagcatcccaccacggtaggaccaaggagagtagttccaggtgccagactcca
gcgacagccaggctgatacaagaggctctggttcgaggaggcctggacaccttggcggct
gatgctgactttgtcacggtgacaggccgggccctggcagatgcctgccagatggaacca
gaggacgtggaggtggcagcaacagagctactgaaaagacaagagtccccagagggcatg
gccagtgcccagggacgcttgagcctcgggtcctcgctggggagccttgaccagcatcag
ggctcccaggagaccctgatcccccgcaggctgtga
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integrated database retrieval system
