Felis catus (domestic cat): 751104 Help Entry 751104            CDS       T02385                                  Symbol KRAS Name (RefSeq) GTPase KRas isoform X2   KO K07827   GTPase KRas Organism fca  Felis catus (domestic cat) Pathway fca01521   EGFR tyrosine kinase inhibitor resistance fca01522   Endocrine resistance fca04010   MAPK signaling pathway fca04012   ErbB signaling pathway fca04014   Ras signaling pathway fca04015   Rap1 signaling pathway fca04062   Chemokine signaling pathway fca04068   FoxO signaling pathway fca04071   Sphingolipid signaling pathway fca04072   Phospholipase D signaling pathway fca04137   Mitophagy - animal fca04140   Autophagy - animal fca04150   mTOR signaling pathway fca04151   PI3K-Akt signaling pathway fca04210   Apoptosis fca04211   Longevity regulating pathway fca04213   Longevity regulating pathway - multiple species fca04218   Cellular senescence fca04360   Axon guidance fca04370   VEGF signaling pathway fca04371   Apelin signaling pathway fca04540   Gap junction fca04550   Signaling pathways regulating pluripotency of stem cells fca04625   C-type lectin receptor signaling pathway fca04650   Natural killer cell mediated cytotoxicity fca04660   T cell receptor signaling pathway fca04662   B cell receptor signaling pathway fca04664   Fc epsilon RI signaling pathway fca04714   Thermogenesis fca04720   Long-term potentiation fca04722   Neurotrophin signaling pathway fca04725   Cholinergic synapse fca04726   Serotonergic synapse fca04730   Long-term depression fca04810   Regulation of actin cytoskeleton fca04910   Insulin signaling pathway fca04912   GnRH signaling pathway fca04914   Progesterone-mediated oocyte maturation fca04915   Estrogen signaling pathway fca04916   Melanogenesis fca04917   Prolactin signaling pathway fca04919   Thyroid hormone signaling pathway fca04921   Oxytocin signaling pathway fca04926   Relaxin signaling pathway fca04929   GnRH secretion fca04933   AGE-RAGE signaling pathway in diabetic complications fca04935   Growth hormone synthesis, secretion and action fca04960   Aldosterone-regulated sodium reabsorption fca05010   Alzheimer disease fca05022   Pathways of neurodegeneration - multiple diseases fca05034   Alcoholism fca05160   Hepatitis C fca05161   Hepatitis B fca05163   Human cytomegalovirus infection fca05165   Human papillomavirus infection fca05166   Human T-cell leukemia virus 1 infection fca05167   Kaposi sarcoma-associated herpesvirus infection fca05170   Human immunodeficiency virus 1 infection fca05200   Pathways in cancer fca05203   Viral carcinogenesis fca05205   Proteoglycans in cancer fca05206   MicroRNAs in cancer fca05207   Chemical carcinogenesis - receptor activation fca05208   Chemical carcinogenesis - reactive oxygen species fca05210   Colorectal cancer fca05211   Renal cell carcinoma fca05212   Pancreatic cancer fca05213   Endometrial cancer fca05214   Glioma fca05215   Prostate cancer fca05216   Thyroid cancer fca05218   Melanoma fca05219   Bladder cancer fca05220   Chronic myeloid leukemia fca05221   Acute myeloid leukemia fca05223   Non-small cell lung cancer fca05224   Breast cancer fca05225   Hepatocellular carcinoma fca05226   Gastric cancer fca05230   Central carbon metabolism in cancer fca05231   Choline metabolism in cancer fca05235   PD-L1 expression and PD-1 checkpoint pathway in cancer fca05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     751104 (KRAS)    04012 ErbB signaling pathway     751104 (KRAS)    04014 Ras signaling pathway     751104 (KRAS)    04015 Rap1 signaling pathway     751104 (KRAS)    04370 VEGF signaling pathway     751104 (KRAS)    04371 Apelin signaling pathway     751104 (KRAS)    04068 FoxO signaling pathway     751104 (KRAS)    04072 Phospholipase D signaling pathway     751104 (KRAS)    04071 Sphingolipid signaling pathway     751104 (KRAS)    04151 PI3K-Akt signaling pathway     751104 (KRAS)    04150 mTOR signaling pathway     751104 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     751104 (KRAS)    04137 Mitophagy - animal     751104 (KRAS)   09143 Cell growth and death    04210 Apoptosis     751104 (KRAS)    04218 Cellular senescence     751104 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     751104 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     751104 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     751104 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     751104 (KRAS)    04650 Natural killer cell mediated cytotoxicity     751104 (KRAS)    04660 T cell receptor signaling pathway     751104 (KRAS)    04662 B cell receptor signaling pathway     751104 (KRAS)    04664 Fc epsilon RI signaling pathway     751104 (KRAS)    04062 Chemokine signaling pathway     751104 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     751104 (KRAS)    04929 GnRH secretion     751104 (KRAS)    04912 GnRH signaling pathway     751104 (KRAS)    04915 Estrogen signaling pathway     751104 (KRAS)    04914 Progesterone-mediated oocyte maturation     751104 (KRAS)    04917 Prolactin signaling pathway     751104 (KRAS)    04921 Oxytocin signaling pathway     751104 (KRAS)    04926 Relaxin signaling pathway     751104 (KRAS)    04935 Growth hormone synthesis, secretion and action     751104 (KRAS)    04919 Thyroid hormone signaling pathway     751104 (KRAS)    04916 Melanogenesis     751104 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     751104 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     751104 (KRAS)    04726 Serotonergic synapse     751104 (KRAS)    04720 Long-term potentiation     751104 (KRAS)    04730 Long-term depression     751104 (KRAS)    04722 Neurotrophin signaling pathway     751104 (KRAS)   09158 Development and regeneration    04360 Axon guidance     751104 (KRAS)   09149 Aging    04211 Longevity regulating pathway     751104 (KRAS)    04213 Longevity regulating pathway - multiple species     751104 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     751104 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     751104 (KRAS)    05206 MicroRNAs in cancer     751104 (KRAS)    05205 Proteoglycans in cancer     751104 (KRAS)    05207 Chemical carcinogenesis - receptor activation     751104 (KRAS)    05208 Chemical carcinogenesis - reactive oxygen species     751104 (KRAS)    05203 Viral carcinogenesis     751104 (KRAS)    05230 Central carbon metabolism in cancer     751104 (KRAS)    05231 Choline metabolism in cancer     751104 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     751104 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     751104 (KRAS)    05212 Pancreatic cancer     751104 (KRAS)    05225 Hepatocellular carcinoma     751104 (KRAS)    05226 Gastric cancer     751104 (KRAS)    05214 Glioma     751104 (KRAS)    05216 Thyroid cancer     751104 (KRAS)    05221 Acute myeloid leukemia     751104 (KRAS)    05220 Chronic myeloid leukemia     751104 (KRAS)    05218 Melanoma     751104 (KRAS)    05211 Renal cell carcinoma     751104 (KRAS)    05219 Bladder cancer     751104 (KRAS)    05215 Prostate cancer     751104 (KRAS)    05213 Endometrial cancer     751104 (KRAS)    05224 Breast cancer     751104 (KRAS)    05223 Non-small cell lung cancer     751104 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     751104 (KRAS)    05170 Human immunodeficiency virus 1 infection     751104 (KRAS)    05161 Hepatitis B     751104 (KRAS)    05160 Hepatitis C     751104 (KRAS)    05163 Human cytomegalovirus infection     751104 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     751104 (KRAS)    05165 Human papillomavirus infection     751104 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     751104 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     751104 (KRAS)   09165 Substance dependence    05034 Alcoholism     751104 (KRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     751104 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     751104 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     751104 (KRAS)    01522 Endocrine resistance     751104 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:fca04131]     751104 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:fca04031]     751104 (KRAS) Membrane trafficking [BR:fca04131]  Endocytosis   Macropinocytosis    Ras GTPases     751104 (KRAS) GTP-binding proteins [BR:fca04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     751104 (KRAS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N MeaB ATP_bind_1 Septin G1_gp67_C TPR_Trm732 NPR1_interact Motif Other DBs NCBI-GeneID:  751104 NCBI-ProteinID:  XP_023112621 LinkDB All DBs Position B4:complement(58557550..58597919) Genome browser AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatatgatcctacaatagaggattcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccactatagagaacaaata aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagatacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

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