| Entry |
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| Symbol |
IDH1
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| Name |
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
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| KO |
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| Organism |
fca Felis catus (domestic cat)
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| Pathway |
| fca01210 | 2-Oxocarboxylic acid metabolism |
| fca05230 | Central carbon metabolism in cancer |
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| Module |
| fca_M00010 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate |
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| Brite |
KEGG Orthology (KO) [BR:fca00001]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
751618 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
751618 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
751618 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
751618 (IDH1)
Enzymes [BR:fca01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
751618 (IDH1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
C1:complement(193520944..193539381)
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| AA seq |
414 aa
MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATGDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTSSDGSKKMTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKVGENLNIKLAQAKL |
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| NT seq |
1245 nt +upstreamnt +downstreamnt
atgtctcaaaaaatccgtggcggttctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggagttgattaaagaaaaactcatttttccctacgtggaactggacctacac
agctatgatttaggcatagagaatcgcgatgccaccggtgaccaggtcaccaaggatgct
gcagaagctataaagaagtacaacgttggtgtcaaatgtgctaccatcacccccgatgag
aagagggttgaggagttcaagttgaagcaaatgtggaagtcaccaaatggcaccatccga
aatattctgggcggcactgtcttcagggaagctatcatctgcaaaaatatcccccgtctt
gtgagcggttgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatataga
gccactgattttgttgttcctgggcctggaaaagtagagataacctacacgtcaagtgat
ggatccaaaaaaatgacatacctggtacataactttgaagaaggtggtggtgttgccatg
gggatgtacaatcaagataagtcgattgaagattttgcacacagttctttccagatggct
ctgtctaagagttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgttttaaagacatctttcaggaaatatatgacaagcagtacaaatcccaattcgaa
gcccaaaatatttggtatgagcataggctcattgatgacatggtggcccaagctatgaaa
tccgaggggggcttcatctgggcctgtaagaactatgacggcgatgtgcagtcggactcc
gtggcccaaggttatggctcccttggcatgatgaccagcgtgctggtttgtccagatggc
aagacagtggaagcagaggctgcccatgggactgtaacacgtcactaccgcatgtatcag
aaaggacaagagacgtccaccaatcccattgcttccatttttgcctggaccagaggatta
gcccacagagctaagcttgataacaataaagagctcagcttctttgcaaaggctttggaa
gaagtctgtattgagaccattgaggctggcttcatgaccaaggacttggctgcttgtatt
aaaggtttgcccaacgtgcagcgttctgactacttgaatacgtttgagttcatggacaaa
gtcggagaaaacttgaatataaaactagctcaggccaaactttaa |
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