Felis catus (domestic cat): 751618
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Entry
751618 CDS
T02385
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00020
Citrate cycle (TCA cycle)
fca00480
Glutathione metabolism
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01210
2-Oxocarboxylic acid metabolism
fca01230
Biosynthesis of amino acids
fca04146
Peroxisome
fca05230
Central carbon metabolism in cancer
Module
fca_M00009
Citrate cycle (TCA cycle, Krebs cycle)
fca_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
751618 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
751618 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
751618 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
751618 (IDH1)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
751618 (IDH1)
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GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Cadherin-like
Motif
Other DBs
NCBI-GeneID:
751618
NCBI-ProteinID:
XP_006935577
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Position
C1:complement(193520944..193539381)
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AA seq
414 aa
AA seq
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MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATGDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTSSDGSKKMTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKVGENLNIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtctcaaaaaatccgtggcggttctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggagttgattaaagaaaaactcatttttccctacgtggaactggacctacac
agctatgatttaggcatagagaatcgcgatgccaccggtgaccaggtcaccaaggatgct
gcagaagctataaagaagtacaacgttggtgtcaaatgtgctaccatcacccccgatgag
aagagggttgaggagttcaagttgaagcaaatgtggaagtcaccaaatggcaccatccga
aatattctgggcggcactgtcttcagggaagctatcatctgcaaaaatatcccccgtctt
gtgagcggttgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatataga
gccactgattttgttgttcctgggcctggaaaagtagagataacctacacgtcaagtgat
ggatccaaaaaaatgacatacctggtacataactttgaagaaggtggtggtgttgccatg
gggatgtacaatcaagataagtcgattgaagattttgcacacagttctttccagatggct
ctgtctaagagttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgttttaaagacatctttcaggaaatatatgacaagcagtacaaatcccaattcgaa
gcccaaaatatttggtatgagcataggctcattgatgacatggtggcccaagctatgaaa
tccgaggggggcttcatctgggcctgtaagaactatgacggcgatgtgcagtcggactcc
gtggcccaaggttatggctcccttggcatgatgaccagcgtgctggtttgtccagatggc
aagacagtggaagcagaggctgcccatgggactgtaacacgtcactaccgcatgtatcag
aaaggacaagagacgtccaccaatcccattgcttccatttttgcctggaccagaggatta
gcccacagagctaagcttgataacaataaagagctcagcttctttgcaaaggctttggaa
gaagtctgtattgagaccattgaggctggcttcatgaccaaggacttggctgcttgtatt
aaaggtttgcccaacgtgcagcgttctgactacttgaatacgtttgagttcatggacaaa
gtcggagaaaacttgaatataaaactagctcaggccaaactttaa
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