Felis catus (domestic cat): 751824
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Entry
751824 CDS
T02385
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 precursor
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca01524
Platinum drug resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04020
Calcium signaling pathway
fca04066
HIF-1 signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04510
Focal adhesion
fca04520
Adherens junction
fca04530
Tight junction
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05206
MicroRNAs in cancer
fca05212
Pancreatic cancer
fca05213
Endometrial cancer
fca05215
Prostate cancer
fca05219
Bladder cancer
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05226
Gastric cancer
fca05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
751824 (ERBB2)
04012 ErbB signaling pathway
751824 (ERBB2)
04066 HIF-1 signaling pathway
751824 (ERBB2)
04020 Calcium signaling pathway
751824 (ERBB2)
04151 PI3K-Akt signaling pathway
751824 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
751824 (ERBB2)
04520 Adherens junction
751824 (ERBB2)
04530 Tight junction
751824 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
751824 (ERBB2)
05206 MicroRNAs in cancer
751824 (ERBB2)
05205 Proteoglycans in cancer
751824 (ERBB2)
05230 Central carbon metabolism in cancer
751824 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
751824 (ERBB2)
05226 Gastric cancer
751824 (ERBB2)
05219 Bladder cancer
751824 (ERBB2)
05215 Prostate cancer
751824 (ERBB2)
05213 Endometrial cancer
751824 (ERBB2)
05224 Breast cancer
751824 (ERBB2)
05223 Non-small cell lung cancer
751824 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
751824 (ERBB2)
01524 Platinum drug resistance
751824 (ERBB2)
01522 Endocrine resistance
751824 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
751824 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
fca04147
]
751824 (ERBB2)
04090 CD molecules [BR:
fca04090
]
751824 (ERBB2)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
751824 (ERBB2)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
751824 (ERBB2)
Exosome [BR:
fca04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
751824 (ERBB2)
CD molecules [BR:
fca04090
]
Proteins
751824 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
751824
NCBI-ProteinID:
NP_001041628
UniProt:
Q49LT4
LinkDB
All DBs
Position
E1:38681441..38705626
Genome browser
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLHANASLSFLQDIQEVQGYVLIAHNQVKQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLKNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPMCEGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFVGCKKIFGSLAFLPGSFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTV
PWDQLFRNPHQALLHSANRPEDECPGEGLACYPLCAHGHCWGPGPTHCVNCSQFLPGQEC
VEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARC
SSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
acgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaagtggtacagggcaacctg
gagctcacctacctgcatgccaatgccagcctctccttcctgcaggatatccaggaggtg
caaggctatgtgctcattgcccacaaccaagtgaaacaggtcccactgcagaggctacga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gacccgctgaagaataccacccctgtcacaggggcctccccaggaggcctgcgggagctg
cagcttcgaagcctcacagagatcttgaaaggaggggtcttgatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggct
ctcacactgatagacaccaaccgctctcgggcctgccacccctgttctccgatgtgtgag
ggctcccgctgctggggagagagttctgaggattgtcagagcctgacgcgcactgtctgt
gccggtggctgtgcccgctgcaaggggccactgcccactgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacacgtttgag
tccatgcccaatcccgagggccggtatacattcggcgccagctgtgtgactgcctgtccc
tacaactacctttctacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctaggcatggagcacctgcgggaggcgagggcagtcaccagtgccaac
atccaagaatttgtcggctgcaagaagatctttgggagcctggcgtttctgccagggagc
tttgagggggacccagcctccaacactgcccccctgcagcctgagcagctcagagtgttt
gaggctctggaggagattacaggttacctgtacatctcagcgtggccagacagcttgcct
aacctcagtgtcttccagaacctcagagtaatccggggccgagttctgcatgacggtgct
tactcgctgacccttcaagggctgggcatcagctggctggggctgcgctcgctgcgggag
ctgggcagtgggctggccctcatccaccgcaactcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagcgccaaccggcca
gaggacgagtgcccgggtgagggcctggcctgctatccgctgtgcgcccacgggcactgc
tggggtccgggacccacccattgtgtcaactgcagccagttccttccgggccaggaatgc
gtggaggaatgccgagtactgcaggggctgccccgggagtatgtgaaggataggttctgt
ctgccatgccacccggagtgtcagccccagaatggctcagtgacctgcttgggctcggaa
gctgaccagtgtgtggcctgtgcccactacaaggaccctcctttctgtgtggctcgctgc
tccagtggggtgaaacctgacctctccttcatgcccatctggaagttcgcagatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggacctggacgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctggtcgtggttgtggggctggtccttggcatcctgatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagcccctg
acgcctagtggagccatgcccaaccaggctcagatgcgaatcctgaaagaaacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcactgtctacaagggcatctggatc
cctgacggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaatacatct
cccaaagccaacaaagaaatcttggacgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtctcgccttctgggcatctgcctgacatccacggtgcagttggtgacacagctt
atgccttatggctgcctcttagaccatgtccgagaacaccgtgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagattttgggctggctcggctgctggacattgacgagacagagtaccatgccgat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
catcagagtgacgtgtggagctacggtgtgactgtatgggaactgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcggccacgtttccgggagctggtggccgaattctcccgtatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagcgagtcccttg
gacagcactttctaccgttcactgctggaggatgaggacatgggagacctggtggatgct
gaggagtacctggtaccccagcagggtttcttctgcccagaccctgccccaggcgctggg
ggcacagcccaccgcagacaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaggaagagcctcccaagtctccactggcaccctcagaaggg
gctggctctgatgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
ctttccccacaggaccccagccctctacagcggtacagtgaggatcctaccgtaccccta
ccccctgagactgatggctacgttgcccccctgacctgcagtccccagcctgaatacgtg
aaccagccagaggtttggccaaagcccccatcgcccttagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctttccccc
ggcaagaatggggttgtcaaagacgtttttgcctttgggggtgctgtggagaaccccgag
tacttggcaccccggggcagggctgcccctcagcctcaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacacatctgagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccccgaatacctggggctggacgtgccagtg
tga
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