KEGG   Felis catus (domestic cat): 768273
Entry
768273            CDS       T02385                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta precursor
  KO
K05425  interleukin 12B
Organism
fca  Felis catus (domestic cat)
Pathway
fca04060  Cytokine-cytokine receptor interaction
fca04620  Toll-like receptor signaling pathway
fca04622  RIG-I-like receptor signaling pathway
fca04625  C-type lectin receptor signaling pathway
fca04630  JAK-STAT signaling pathway
fca04658  Th1 and Th2 cell differentiation
fca04936  Alcoholic liver disease
fca04940  Type I diabetes mellitus
fca05133  Pertussis
fca05134  Legionellosis
fca05140  Leishmaniasis
fca05142  Chagas disease
fca05143  African trypanosomiasis
fca05145  Toxoplasmosis
fca05146  Amoebiasis
fca05152  Tuberculosis
fca05162  Measles
fca05164  Influenza A
fca05168  Herpes simplex virus 1 infection
fca05171  Coronavirus disease - COVID-19
fca05200  Pathways in cancer
fca05205  Proteoglycans in cancer
fca05321  Inflammatory bowel disease
fca05330  Allograft rejection
fca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    768273 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    768273 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    768273 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    768273 (IL12B)
   04625 C-type lectin receptor signaling pathway
    768273 (IL12B)
   04658 Th1 and Th2 cell differentiation
    768273 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    768273 (IL12B)
   05205 Proteoglycans in cancer
    768273 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    768273 (IL12B)
   05164 Influenza A
    768273 (IL12B)
   05162 Measles
    768273 (IL12B)
   05168 Herpes simplex virus 1 infection
    768273 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    768273 (IL12B)
   05134 Legionellosis
    768273 (IL12B)
   05152 Tuberculosis
    768273 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    768273 (IL12B)
   05145 Toxoplasmosis
    768273 (IL12B)
   05140 Leishmaniasis
    768273 (IL12B)
   05142 Chagas disease
    768273 (IL12B)
   05143 African trypanosomiasis
    768273 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    768273 (IL12B)
   05330 Allograft rejection
    768273 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    768273 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    768273 (IL12B)
   04936 Alcoholic liver disease
    768273 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:fca04052]
    768273 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:fca00536]
    768273 (IL12B)
Cytokines and neuropeptides [BR:fca04052]
 Cytokines
  Interleukins
   768273 (IL12B)
Glycosaminoglycan binding proteins [BR:fca00536]
 Heparan sulfate / Heparin
  Cytokines
   768273 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_3 Ig_5 Ig_4 Ig_2 I-set ig fn3 IntS9_C DBD_Tnp_Mut
Other DBs
NCBI-GeneID: 768273
NCBI-ProteinID: NP_001070881
UniProt: O02744
LinkDB
Position
A1:188473697..188483167
AA seq 329 aa
MHPQQLVIAWLSLVLLAPPLMAIWELEKNVYVVELDWHPDAPGEMVVLTCNTPEEDDITW
TSDQSSEVLGSGKTLTIQVKEFADAGQYTCHKGGEVLSHSFLLIHKKEDGIWSTDILREQ
KESKNKIFLKCEAKNYSGRFTCWWLTAISTDLKFTVKSSRGSSDPQEVTCGAATLSAEKV
RVDNRDYKKYTVECQEGSACPAAEESLPIEVVVDAIHKLKYENYTSSFFIRDIIKPDPPK
NLQLKPLKNSRHVEVSWEYPDTWSTPHSYFSLTFGVQVQGKNNREKKDRLSVDKTSAKVV
CHKDAKIRVQARDRYYSSSWSNWASVSCS
NT seq 990 nt   +upstreamnt  +downstreamnt
atgcatcctcagcagttggtcatcgcctggctttccctggttttgctggcacctcccctc
atggccatatgggaactggagaaaaacgtttatgttgtagagttggactggcaccctgat
gcccccggagaaatggtggtcctcacctgcaatactcctgaagaagatgacatcacctgg
acctctgaccagagcagtgaagtcctaggctctggtaaaactctgaccatccaagtcaaa
gaatttgcagatgctggccagtatacctgtcataaaggaggcgaggttctgagccattcg
ttcctcctgatacacaaaaaggaagatggaatttggtccactgatatcttaagggaacag
aaagaatccaaaaataagatctttctaaaatgtgaggcaaagaattattctggacgtttc
acctgctggtggctgacggcaatcagtaccgatttgaaattcactgtcaaaagcagcaga
ggctcctctgacccccaagaggtgacttgtggagcagcgacactctcagcagagaaggtc
agagtggacaacagggattataagaagtacacagtggagtgtcaggagggcagtgcctgc
ccggctgccgaggagagcctacccattgaagtcgtggtggacgctattcacaagctcaag
tacgaaaactacaccagcagcttcttcatcagggacatcatcaaaccggacccacccaag
aacctgcaactgaagccattaaaaaattctcggcatgtggaagtgagctgggaataccct
gacacctggagcaccccacattcctacttctccttaacatttggcgtacaggtccagggc
aagaacaacagagaaaagaaagacagactctccgtggacaagacctcagccaaggtcgtg
tgccacaaggatgccaagatccgcgtgcaagccagagaccgctactatagctcatcctgg
agcaactgggcatccgtgtcctgcagttag

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