Francisella hispaniensis FSC454: FSC454_02420
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Entry
FSC454_02420 CDS
T04700
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fhi
Francisella hispaniensis FSC454
Pathway
fhi00300
Lysine biosynthesis
fhi00550
Peptidoglycan biosynthesis
fhi01100
Metabolic pathways
fhi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fhi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FSC454_02420
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FSC454_02420
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FSC454_02420
Enzymes [BR:
fhi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FSC454_02420
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ACBP4_C
Motif
Other DBs
NCBI-ProteinID:
APD50074
UniProt:
A0AAC9J4P6
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All DBs
Position
486479..487837
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AA seq
452 aa
AA seq
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MIKSLKQLATQAGLEYLGEDVSIQTVAINSNEVRQDCLFVAIIANRDGHEFIPSAIANRA
KAVLVSKKQDLDIPQVVCSNTIKGLRALAKEYRKTLTMPTISLTGSCGKTTVKEMIVTLL
GGKKVHFTQGNLNNYLGVPMTILETPHDVDFAVIEAGTNVGGEIKAAADIIQPNIAMITN
VGASHLENLKTLDGVMIEKGELLKALPKDGFCIVNLDDERIPNYAYKLDCKKITCSMSNQ
DADILILDYQVTPELYDVKIRIFDKEYSYQLPNIGKHNLSNSMLAIASVVAAGLEPNSFL
QNTQNIKNYKGRFSTEKLNDKLTLVDDTYNASAGAVQAAIEDLAEFDGKKVIAITSMREL
GDEAENYHRKMGQWLNEANLDKIFLFGEKKLIKFALEEYKNSNVKYYDDKQQLNDDLLKV
LTEYKSQNTKLTVKGARSFKMEEVVAFVKQII
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatcaagtcactaaaacaattagcaacccaagcaggcttagaatatttgggtgaagat
gtatcaatacaaacagtagctataaattcaaacgaagtaagacaagattgcttatttgtt
gcaattatagctaatcgtgatgggcatgagtttattccaagtgctattgctaatcgcgct
aaagctgttctagtttcaaaaaaacaggatttagatatcccacaagtagtttgtagtaat
actatcaaaggcttacgagctttagccaaagagtatcgtaaaactctaactatgccgaca
atatccttaacaggtagttgtggtaaaacaacggttaaagagatgatagtaactctactt
ggaggtaaaaaagttcactttactcaaggtaatctaaataattatcttggtgtgccaatg
acaatactagaaaccccacatgacgttgattttgcggtgattgaggccggtacaaatgtt
ggcggtgaaataaaagccgctgctgatattatccaaccaaatatagcgatgattacaaat
gttggagctagtcacttagagaatttaaaaacattagatggtgtaatgatagaaaaaggt
gagcttcttaaagctctacccaaagacggcttttgtattgtaaatcttgatgatgaaaga
ataccaaactatgcatataaattagactgtaagaaaattacttgctcaatgagtaatcaa
gatgctgatattttgattttagattatcaggttactccagagttatacgatgttaagatt
agaatttttgacaaagaatatagctatcagttgccaaatattggtaaacataatttgtct
aatagtatgcttgcaatagctagtgtagtcgctgcaggactcgaaccaaacagtttttta
caaaatacgcaaaatatcaaaaattataaaggtagattttcaactgaaaagctaaatgat
aagttaactcttgtagatgatacatataatgctagtgctggagctgtccaagctgccatt
gaagatttggctgaatttgatggtaaaaaagttatagcaattacctcaatgagagaatta
ggtgatgaggctgaaaattatcatcgtaagatgggacaatggcttaatgaagcaaactta
gataagatatttctatttggcgaaaaaaaattaataaagtttgctttagaagagtataaa
aattcaaatgtcaaatactatgatgacaagcaacagctaaatgatgatctattaaaagta
cttactgagtataaatcgcaaaatactaaacttactgtcaaaggagctagaagcttcaag
atggaagaagttgtagctttcgttaagcagataatatag
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