Facklamia hominis: R0V13_04185
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Entry
R0V13_04185 CDS
T09549
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase family protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
fhm
Facklamia hominis
Pathway
fhm00790
Folate biosynthesis
fhm01100
Metabolic pathways
fhm01240
Biosynthesis of cofactors
Module
fhm_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
fhm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
R0V13_04185
Enzymes [BR:
fhm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
R0V13_04185
6.3.2.17 tetrahydrofolate synthase
R0V13_04185
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
YqeC
NTPase_1
Motif
Other DBs
NCBI-ProteinID:
WPJ91564
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Position
837084..838433
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AA seq
449 aa
AA seq
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MEFTRIEEATDWLLNQVNPIPRPDMTKMYQALEYMGNSHLGLPVLHITGTNGKGSVVAYL
RDLFQSQGLNVGSFTSPHIERFNERISYNHEQISDEAVIRWTNRLKELNTYMETHSEYGR
LIYFELFTILACLYFQEKKPDVCLIEAGIGGMHDCSNVLDGQVSVITSIGLDHAEMLGDT
KEKVAYEKAGIIKPGRSAVTGYMEEGPLAVIDQWSHNHHAKAYHYDKEYQVSQVKDLGPH
GAEFIFKSPLCLNESLAVKIAMIGEHQVHNAATALQAFILWMQGHHLEIDWSKALQALSQ
THWIGRLEAISEQPLIYLDGAHNMEGLTALKEVVSHQFKDYQIELVYAGLRKKNQHDQVP
LLLTFEVDQVNFTGFDHFESMELEDFQAILEQTDKPIEQAYHFIEDWPTWIDQYCHDHSG
SDRSLLLITGSLYFVSQVREYILSQKLNG
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atggaatttacaaggattgaagaagcaacggactggcttttaaatcaagtcaatccgata
ccacgtccggatatgacgaagatgtatcaagcattagaatacatggggaattcccatctt
gggttgccggtccttcatattacggggaccaatggtaaaggctcggtggtcgcttatttg
agagacttatttcaaagtcagggcttaaatgtgggttcttttacttcaccacatattgag
cgatttaatgaacggattagttataaccatgaacagatctcagatgaagcggttattcgt
tggacaaaccgtttaaaagaattgaatacttatatggagactcattcagagtacggtcgc
ttaatatattttgaattgtttaccatattagcctgcttatactttcaagaaaagaagcct
gatgtatgtcttattgaagcgggtattggtggaatgcatgattgttctaatgttctggat
ggacaggtatctgttatcacatccattggtttagaccatgcagaaatgttgggtgatact
aaagaaaaggtcgcttatgagaaagcgggaattattaagccaggccgaagtgcagtgacg
ggttatatggaagagggtccattagcggttatcgaccagtggagtcataaccatcatgct
aaagcctatcactatgacaaagagtatcaagtcagtcaggttaaagatttggggcctcac
ggggcagaatttatttttaagagtcctttatgtttgaatgaatcattagcggtaaagatt
gctatgattggtgaacatcaagtccacaatgcagcaactgctttacaagcgtttattcta
tggatgcaaggccatcatttagaaattgattggtccaaggctcttcaagctttgagccag
actcactggatcggtcgtttggaagcaattagtgagcagcctttgatttatctggatggg
gctcataatatggaaggattaacagctttaaaagaagttgtctcccatcaatttaaagac
tatcagattgaattggtttatgctggactaagaaagaaaaatcagcacgaccaagttcct
ttattattaacttttgaggttgatcaggttaattttaccggctttgatcattttgaatct
atggaattggaagacttccaagctatcttagaacaaacggataagccgatagaacaggcg
tatcattttattgaagattggccgacatggatcgaccagtattgtcatgaccatagtgga
tctgatcgttctttactgttgataacaggttctttatattttgtctcacaagttcgggaa
tacattctatcacaaaagcttaatggttaa
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