Faecalibacillus intestinalis: Fi14EGH31_04410
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Entry
Fi14EGH31_04410 CDS
T06868
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fit
Faecalibacillus intestinalis
Pathway
fit00300
Lysine biosynthesis
fit00550
Peptidoglycan biosynthesis
fit01100
Metabolic pathways
fit01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fit00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Fi14EGH31_04410 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Fi14EGH31_04410 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Fi14EGH31_04410 (murF)
Enzymes [BR:
fit01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Fi14EGH31_04410 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF5659
DUF3244
Motif
Other DBs
NCBI-ProteinID:
BCL56729
UniProt:
A0A7I8DVS4
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Position
431950..433281
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AA seq
443 aa
AA seq
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MKVYEILEATKGILVSGNKEDEICFFSQDSRQMKHGGMYIPLKGERFDGHDFIESAFQTG
ATAIITAKDVSYPDKIVIKVEDTYQALKDMAIYLRSHRPVKVVGVTGSVGKTSTRDMVYS
VVKQKYKTLKTEGNYNNEIGLPLTILRYQDEEVMVLEMGMNHLNEMSRLSMIAHPDVSCI
TNVGTAHIGELGSRENILKAKLEITDGMKDQSTLIINNDNDMLQTVDLPRLNVVRVGKNE
GASIQASDIELFEDHSTFIVHYHDQSEKIWVPVQGEHNVFNALIAIAVGIELNISLEDIK
KGIQEFKLTKNRMDILEKNHKTIIDGTYNASVDSMKSSIDVLANYKKRKVAILADMLELG
SYSQQLHEEVGNYVATKEIDVLICIGKEAKYMYQKAKEKMKNVYYFTSNQEVIEQLDQFL
KNDDVVLVKGSHSMNLKEIVEKI
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtatatgaaatattagaggcaacaaaaggtattttagtttctggaaataaagaa
gatgagatttgtttctttagtcaagatagtagacaaatgaaacatggaggaatgtatatt
cctttaaaaggtgaaagatttgatggacatgattttattgaaagtgcttttcaaacagga
gcaacagcaattattaccgctaaagatgtaagttatccagataaaattgtgattaaagta
gaagatacttatcaagctttaaaagatatggccatttatttaagaagtcatcgccctgta
aaggttgtgggagttacaggaagtgttggaaaaacaagtacacgtgatatggtctatagt
gttgttaaacaaaaatataaaactttaaaaacagaaggtaattataataatgaaataggt
ctaccattaacaattttaagatatcaagatgaagaagtcatggtcttagaaatggggatg
aatcatttaaatgaaatgtcaagattatctatgattgctcatcctgatgtctcatgtatt
accaatgttggaacagcacatattggtgaactaggaagtcgtgaaaatattttaaaagca
aagttagaaattactgatggtatgaaagatcaatccactttaattattaataatgataat
gatatgttacagactgttgatttacctcgtttaaatgttgtaagagttggaaaaaatgaa
ggggcttctattcaagcaagtgatattgaattatttgaagatcacagtacatttattgtt
cattatcatgatcaaagtgaaaaaatttgggttcctgttcaaggagagcataatgttttt
aatgcactaattgcgatagcggtaggtattgaattaaatatttctttagaagatattaaa
aaaggaattcaagaatttaaattaacgaagaatcgtatggatattcttgaaaaaaatcat
aaaacaattattgatggaacatataatgcaagtgtagattcaatgaaatcaagtatagat
gttctagcaaattataaaaaacgtaaagttgctattttagcggatatgttagaactcgga
agttatagtcaacaacttcatgaagaagtgggaaactatgttgctactaaagaaatagat
gttttgatttgtattgggaaagaagcaaagtatatgtatcaaaaagcaaaagaaaaaatg
aagaatgtttattattttacttctaatcaagaagttattgaacaattagatcaattttta
aagaatgatgatgtggttttagttaaaggaagtcactctatgaatttaaaagaaattgta
gaaaagatataa
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