Francisella marina: F0R74_01045
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Entry
F0R74_01045 CDS
T06206
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
fmi
Francisella marina
Pathway
fmi00260
Glycine, serine and threonine metabolism
fmi00261
Monobactam biosynthesis
fmi00270
Cysteine and methionine metabolism
fmi00300
Lysine biosynthesis
fmi01100
Metabolic pathways
fmi01110
Biosynthesis of secondary metabolites
fmi01120
Microbial metabolism in diverse environments
fmi01230
Biosynthesis of amino acids
Module
fmi_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
fmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
F0R74_01045 (thrA)
00270 Cysteine and methionine metabolism
F0R74_01045 (thrA)
00300 Lysine biosynthesis
F0R74_01045 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
F0R74_01045 (thrA)
Enzymes [BR:
fmi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
F0R74_01045 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
F0R74_01045 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
GFO_IDH_MocA
DUF5718
DapB_N
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
QEO56493
LinkDB
All DBs
Position
207983..210403
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AA seq
806 aa
AA seq
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MIVHKFGGSSLATSEKIKNVSNIISCIDEAVVVSASAKTTSNLQKAIDQAIESQDYSETL
NFIFEHHSSILHDLVPADNTLRETILKDLRDIKHILSTIVITGFCADSLRFFILGFGEIW
SAKILTLYLQSRDKNAYFIDASECLIVNDSNYPVTVNWQQSTESIEAIKSENPADVYVIT
GFIAQNKLGKRTILGLNCSDYSAAIFAKLLQADKLYIWTDVAGVYSANPQVVPEAKPLTQ
LTYKEALELAYFGASVVHPLTIAPMALERTPIYIKSSYSPDEVGTKISADKDEDQGLIKG
LTSVSDVAIVRVQGAGMIGVSGISFKVFGALEKAGVSVMMISQASSEYSICFAIDSVNAD
RATETLKHEFANEIKNNLIEEIAVHKHHALITAVGEGMKSKTGSLAKLVNSLKLANINIH
AIAQGSSERSVTFAVKAEDEARGVQAMHRHYNSVSDDIAIAVIGAGNIGKAFIKQIKQTY
EKWYSKGINLVLVGATNSKQMRVSYENLLFENIGNLLNENTEQANLEKLAEFMSHASATK
KIVIDATASEDVSKSYANFLNNGISVITPNKYANSGNYEFYQELRKVANQNGTSFLYETN
VCAGLPLIVTLQNMVQSGDHVRSINGIFSGTLSYLFTQLNNGVIFSDAVKMAYDAGYTEP
DPRQDLSGMDVARKTVILAREIGLNIGLNDLVIENLVPEELRECSVEEFFVKLPAFNEQI
MQQIADKKKDLAGVHYVGSIVNGVANVGIQAYDESSPFANVKGTDNIVMINTDRYTQPMV
IQGAGAGVEVTAAGVYADVITVIREK
NT seq
2421 nt
NT seq
+upstream
nt +downstream
nt
atgatagtacataagtttggaggcagtagtttagctacatcagagaagataaaaaatgtt
tcgaatataattagttgtatcgatgaggctgtggtagtttctgcatcagcaaaaactact
agtaatttacaaaaagctatagatcaagcaattgagtctcaagattatagcgaaacactt
aattttatttttgagcatcatagttctatacttcatgatttagttcccgctgataatact
ttaagagaaacgattcttaaagatttaagagatattaagcatattctcagtactatagta
attacagggttctgcgctgatagtttgagattctttattttgggctttggggaaatatgg
tcagctaaaattcttacgttatatttgcaatcaagagataagaatgcgtattttatagat
gcttcagaatgtttgattgtcaatgatagtaattatcctgttacagttaattggcaacaa
agcacggagtcaatcgaggctataaaatctgaaaatcctgctgatgtatatgttatcaca
ggttttattgctcaaaataagcttggtaagagaacaatattaggcttaaactgtagtgac
tattcagcagctatttttgcaaagctattacaagctgataagctatatatttggacagat
gtggctggtgtatacagtgctaatccacaagtagttccagaggcaaaacctctaactcaa
ttaacatataaagaggctcttgagcttgcttattttggtgcatctgttgtacatccttta
actatagccccaatggctctagagagaacacctatttatataaaaagtagttattcccca
gatgaggttggtactaagattagtgctgacaaggatgaagaccaaggtcttattaaaggc
ctaacaagtgtctcagatgtggcgatagtacgagtgcaaggtgctggtatgataggtgtt
tctggtatatcgttcaaagtttttggagcactagagaaagcaggtgtatctgtaatgatg
atatctcaagcgagctctgaatattctatatgttttgctatagatagtgtcaatgctgat
agggcaaccgaaactttaaaacatgagtttgctaatgagataaagaataatcttattgaa
gaaattgctgttcataagcatcatgctttgattacggcagttggtgaaggtatgaagtct
aagactggatcgttagcaaagttggtaaactctcttaagttagcaaatataaatatacat
gctattgctcaagggtcctcagagagaagtgttacatttgcagtaaaagctgaggatgaa
gctagaggtgtccaagctatgcatcgtcactataattctgtaagtgatgatattgcaatt
gctgtaattggtgctggtaatattggtaaggcttttattaagcaaattaaacaaacttat
gaaaaatggtattcaaaaggtattaacttagtattggtaggagctactaactcaaagcaa
atgcgtgtctcttatgaaaatttattatttgaaaatataggtaatctacttaatgagaat
acagagcaagctaatctagagaagttggctgaatttatgtctcatgcttcggctaccaaa
aaaattgtgattgatgctacagcaagtgaagatgtttcgaaaagttatgctaatttttta
aacaacggaatcagtgtaattactcctaataagtatgcaaattcagggaactatgaattc
tatcaagagcttagaaaagtcgctaatcagaatggcactagtttcttatatgaaacaaat
gtttgtgcaggccttcctctcatagttacattgcaaaatatggttcaaagtggtgatcat
gttagatctataaatggtattttctcaggaactttaagttatttgtttactcagttaaat
aatggtgtgattttctcagatgcagttaaaatggcttatgatgctgggtatacagagcca
gatccaagacaagatttatcaggtatggatgtcgcaagaaagactgtgatcttagctaga
gaaataggtctaaatataggtctgaatgacttggttattgaaaatttagtacctgaagaa
ttacgtgaatgtagtgtagaagagttttttgttaaacttccagcatttaacgagcaaata
atgcaacaaattgcagacaaaaagaaagatcttgctggagtacattatgttggatctatc
gttaatggtgttgcaaatgtaggtatccaagcttatgatgaatctagtccttttgcaaat
gtgaaaggtactgataatatcgtgatgataaatacagatagatatactcaacctatggtt
atccaaggtgctggtgctggtgttgaggtaacagcagcaggtgtatatgctgatgttata
actgtgataagagaaaagtag
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