KEGG   Flavobacterium nackdongense: E1750_13000
Entry
E1750_13000       CDS       T06713                                 
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
fnk  Flavobacterium nackdongense
Pathway
fnk00260  Glycine, serine and threonine metabolism
fnk00261  Monobactam biosynthesis
fnk00270  Cysteine and methionine metabolism
fnk00300  Lysine biosynthesis
fnk01100  Metabolic pathways
fnk01110  Biosynthesis of secondary metabolites
fnk01120  Microbial metabolism in diverse environments
fnk01230  Biosynthesis of amino acids
Module
fnk_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
fnk_M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:fnk00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    E1750_13000 (thrA)
   00270 Cysteine and methionine metabolism
    E1750_13000 (thrA)
   00300 Lysine biosynthesis
    E1750_13000 (thrA)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    E1750_13000 (thrA)
Enzymes [BR:fnk01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     E1750_13000 (thrA)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     E1750_13000 (thrA)
SSDB
Motif
Pfam: AA_kinase Homoserine_dh ACT_9 Abhydrolase_1 NAD_binding_3 ACT_7 ACT DALR_1
Other DBs
NCBI-ProteinID: QBN19681
UniProt: A0A4P6Y9G5
LinkDB
Position
3046894..3050280
AA seq 1128 aa
MENKPTTITLQNFTTESGILISSINLSYQVFGQVLNTAPIVLVNHALTGNSQVVGENGWW
NNLIGDNKTIDTNKYTILAFNVPGNGFDKTYIENYLDFTARDIARLFLEGIRLLKVKDVF
ALIGGSVGGGIAWEMIALEPKLTHNFFPIASDWKSTDWLIANCYLQEKILCNSSKPIEDA
RIHAMLCYRTPESFKEKFQRTSMDSTDSFQVESWLNHHGEKLQKRFQLSAYKMMNQLLKT
IDITRGRTSFEELISEVDANIYIIGINSDLFFTANENRETYHEIKKFKHNVFYSEIESQH
GHDAFLMEYEQLNNLLDVVFKNKKDKMKILKFGGKSLANGEGINKVLDIIIDKKSKGENI
AVVVSARGKATDELEDILTIAAKNGNYKPLLESFKSYQQDGYTVDLSEEFTVLDKLFEGV
SLIGDYSEKIKDLVLAQGELLSAKLITAVLNEKGIKSCFADTRELIKTDSHFGDAQPLEQ
ISKKNIVHFFKENNDTVNIITGFIGSNASGDTTTLGRNGSNYSASLIANYLDAEELQNYT
HVDGIYTANPELVPDAKKIDRLSFNEANEIANFGATILHAKTIIPLLEKNIPLRILNTFN
HENQGTLITSKSNAAGIKTLSVLENVALVNLEGRGLLGKTGVDARIFKVMGDNDISVSII
SQGSSERGIGLVVNSNQATKAMIELEKEFENDFYSKDVNKISITDDVSVISIIGQDLSTF
HKPYTSLIKNKVVPILFNNTVTGKNVSLVVKKSELNKALNVIHGEIFGVSKKINIAIFGH
GLVGGTLINQILESAPSIEKRKDIKLNVFAIANSKNLLLNKNGVSPNWKNEIQTNGFSYT
IDDVIAFANENNMENLIAIDNTASATFVENYVKLAENSFDLISSNKVANTLSYKFYKDLR
KVLAENQKNYLYETNVGAGLPLIDTIKLLHLSGENITKIKGVFSGTLSYLFNNFSAKDVP
FSEILKEAIDNGYTEPDPREDLCGNDVGRKLLILARELDLQNEFEEISIQNLIPEHLREG
SVADFLNKLKEFDPIYTKIKEDQEPNHVLRYIGELSGDLQNDKGNLEVKLVSVPSDTALG
GLKGSDSFFEIYTESYGDRPIVIQGAGAGSAVTARGVFGDLLRLSEKG
NT seq 3387 nt   +upstreamnt  +downstreamnt
ttggaaaataaaccaacaaccatcacattacaaaatttcaccaccgaaagtggcatactc
atttcttccatcaacctaagttatcaggtttttggacaagttttgaatacagctcctatc
gttttggtcaatcacgccttgaccggaaattcgcaagttgtgggtgaaaacggctggtgg
aataatcttattggcgacaataaaaccatcgacaccaataaatacaccattttagctttc
aacgttccgggaaatggattcgataaaacctatattgaaaattatttggattttacagct
cgagatattgccagactttttctggaaggcattcgattgctgaaagttaaagatgtcttt
gccctgattggtggctctgtcgggggcggaattgcttgggaaatgatagctttggagcct
aaattaactcataattttttcccgattgcttccgattggaaatcgaccgattggttgatt
gccaattgttatttgcaagaaaaaattctttgtaattcgtccaaacccatcgaagacgcg
cgtattcacgcgatgttgtgttacagaacacccgaatctttcaaggaaaaatttcaaaga
acctctatggattctaccgattcttttcaagtggaaagttggttgaatcatcacggcgaa
aagttgcaaaaacgttttcagctttcggcttacaaaatgatgaatcagttgttgaaaacc
atcgatatcactcgcggaagaacctcgtttgaagaactaatttcagaagtcgatgccaat
atttatatcatcggaatcaattcggatttgttttttacagccaatgaaaaccgcgaaact
taccacgaaatcaaaaaattcaagcacaatgttttttatagcgaaatcgaatcgcaacac
ggacacgacgcttttttaatggaatacgaacaattaaacaatttactggatgttgttttt
aaaaacaaaaaggataaaatgaaaatattaaaatttggcggaaaatcattggccaacggc
gaaggaatcaataaagttttagatattattattgataaaaaaagcaaaggcgaaaacatt
gcagttgtggtttcggctagaggaaaagccacagatgaattagaagatattttgaccatt
gctgccaaaaacggcaattacaaacctctgttagaaagtttcaaaagctatcagcaagac
gggtataccgttgatttgtctgaagaatttactgttttagacaaacttttcgaaggtgta
agtttgattggcgattatagcgaaaaaatcaaagatttagtattggcacaaggcgaattg
ctttcggcaaaattgattaccgctgttttgaacgaaaaaggaattaaatcctgttttgca
gataccagagaattgatcaaaaccgattctcactttggcgatgcgcaacccttggagcaa
atttcaaagaaaaatatcgtccattttttcaaagaaaataacgatacagtcaatataatt
actggttttattggttccaacgctagtggtgacacaacgactttaggacgaaacggcagt
aattactcggcttcactgattgctaattatcttgatgccgaagaattgcaaaactacacc
cacgtcgacggaatttataccgccaacccagaattagttcccgatgccaaaaaaattgac
cgtttgtcgtttaacgaagcaaacgaaattgccaattttggagctaccattttacacgca
aaaaccataatccctttattggaaaaaaatattccgttgcgaattctgaatactttcaat
cacgaaaatcaagggactttaatcacgtcaaaatcgaatgcagcaggaattaaaaccctt
tcggttctagaaaatgtggctttggtcaaccttgaaggaagaggattgttgggaaaaaca
ggtgtcgatgcgcgtatttttaaagtaatgggtgacaatgacattagcgtaagcatcatt
tcgcaaggttcgtcagaaagaggaattgggcttgtggttaattccaatcaagcgaccaaa
gcgatgatcgaattggagaaagaattcgagaatgatttctattcgaaagacgtaaacaaa
atctccattactgatgatgtttcggtgatttcgattattggtcaggatttgagtactttc
cataaaccgtacacatcgttgataaaaaacaaggttgtacctattcttttcaacaatacg
gtaacgggtaaaaacgtgagtttggtagtgaagaaatcggagttgaacaaggcgttgaac
gtgattcacggggagatttttggagtttctaagaaaattaatattgctattttcggtcac
ggattggtaggtggaactttgattaatcaaattttagaatcagctccatccatcgaaaaa
aggaaggatattaagttaaatgtttttgcaattgccaattctaaaaatctgcttttgaac
aaaaacggcgtttctccaaattggaaaaacgaaattcaaactaacggtttttcgtatacg
atcgatgatgttattgctttcgccaatgaaaataatatggagaatttgattgccatagac
aacacggcaagcgctacttttgttgagaattacgtgaaattggcagaaaatagtttcgat
ttaatttcttcgaataaagtggcaaatacattgagttataaattttacaaagacttgcga
aaagtattggcagaaaaccagaagaattatttgtacgaaaccaatgttggtgcaggttta
ccattgattgacaccatcaaattattgcatctttcgggtgaaaatatcaccaaaatcaaa
ggtgttttctctggaacattgagttatttgttcaataatttctctgccaaagatgttccg
tttagcgaaattttgaaggaagccatcgacaacggttacaccgaacccgatccaagagaa
gatttatgcggaaatgatgtgggtagaaaattactaattttggcgagagaactggatttg
caaaacgaattcgaagaaattagcattcaaaacttaattccagaacatttgcgtgaagga
agtgttgccgatttcttgaataaattgaaagaattcgacccaatttataccaaaataaaa
gaagaccaagaaccgaatcatgtgttgagatacattggtgaattgtcgggcgatttacaa
aatgacaaaggaaatctagaagtaaaattagtttccgtaccttcggatactgctttgggc
ggattgaaaggttctgattcgttcttcgaaatttacaccgaatcctacggagaccgacca
atcgtaattcaaggcgctggtgcaggatcggctgtgacagcgagaggtgttttcggagat
ttattgagattgtcggaaaaaggttag

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