Faecalibacterium prausnitzii SL3/3: FPR_06280
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Entry
FPR_06280 CDS
T02592
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthases
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
fpa
Faecalibacterium prausnitzii SL3/3
Pathway
fpa00290
Valine, leucine and isoleucine biosynthesis
fpa00620
Pyruvate metabolism
fpa01100
Metabolic pathways
fpa01110
Biosynthesis of secondary metabolites
fpa01210
2-Oxocarboxylic acid metabolism
fpa01230
Biosynthesis of amino acids
Module
fpa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
fpa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
FPR_06280
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FPR_06280
Enzymes [BR:
fpa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
FPR_06280
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
RFX1_trans_act
Motif
Other DBs
NCBI-ProteinID:
CBL01014
UniProt:
D4K851
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All DBs
Position
642603..644255
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AA seq
550 aa
AA seq
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MMDATKYAPGYYPVPAGYDSWVKKDHIEKAPAWCSVDLRDGNQALIVPMSLAEKLEFFQM
LVKIGFKEIEVGFPAASETEYEFLRTLIEKNMIPADVTVQVLTQCRDHIIRRTFEAVKGA
PRAVIHFYNSTSVAQREQVFHKSKEEIKQIAVDGAKLVKQLSEEYEGNFLFEYSPESFTG
TEVDYAVEVCNAVLDIMQPTPERPMIINLPVTVEMSMPHVYANQIEYCDKHLKYRDSVII
STHPHNDRGTGVACAELAVLAGAQRVECCLFGNGERTGNVDAVTLAMNMYSHGVDPKLDF
SDMPAICATYERVTRMHIYERTPYAGQLVFAAFSGSHQDAIAKGMAYRKQTGEHRWTCPY
IPVDPHDIGRTYDADVIRINSQSGKGGIGFVLEQNYGYNLSPKMREALGYKVKSVSDHSH
KELSAAEVLHIFEDTYLNRAKPLNVVEAHFAQVNGITATVTLELNGQRKVVTSVGNGRLD
AVANAIQSATGMDFHLENYSEHSLDEGSTSRAASYVGLVWGDNTVTWGAGTDTDIIVAGI
RALVSAINNR
NT seq
1653 nt
NT seq
+upstream
nt +downstream
nt
atgatggacgctaccaagtacgcaccggggtactatccggtacccgccggttatgacagc
tgggtaaaaaaagaccatattgaaaaggctcccgcatggtgcagcgtggatctgcgggac
ggcaatcaggcgctgatcgtgcccatgagccttgcagaaaagctggagttcttccagatg
ctggtgaagatcggcttcaaggaaatcgaggtgggcttccccgccgccagtgagaccgag
tacgagttcctgcgcaccctgatcgaaaagaatatgattcccgccgatgtcaccgtgcag
gtgctgacccagtgccgcgaccacatcatccgccgcaccttcgaggccgtcaagggcgca
ccccgggcggtgatccatttctacaactccacctccgtggcacagcgggagcaggtgttc
cacaagtccaaagaggagatcaagcagatcgccgtggacggtgcaaagctggtcaagcag
ctcagcgaggagtacgagggcaacttcctgtttgagtacagccccgaaagctttaccggc
accgaggtggattacgccgtagaggtgtgcaacgccgtgctggatatcatgcagcccacc
ccggagcgccccatgatcatcaacctgccggtgaccgtggagatgagcatgccccatgtg
tacgccaaccagatcgagtactgcgacaagcacctgaagtaccgcgacagcgtgatcatc
tccacccatccccacaacgaccgcggcactggcgtagcctgcgcagagttggcagtgctg
gcgggcgcacagcgcgtggagtgctgcctgtttggcaacggcgagcgcaccggcaatgtg
gacgccgtaacgctggccatgaatatgtacagccacggcgtagaccccaagctggacttc
tcggatatgcccgccatctgcgccacctacgagcgggtgacccggatgcacatctacgag
cgcaccccctacgccgggcagctggtgtttgccgccttctccggtagccatcaggacgcc
attgccaagggcatggcgtaccgcaagcagaccggcgaacaccgctggacctgtccctac
atcccggtggacccccacgacatcggccgcacctacgatgccgacgttatccgcatcaac
agccaaagcggcaagggcggcatcggttttgtactggaacagaactacggctacaatctg
tcccccaagatgcgggaggcgctgggctacaaggtcaagagcgtgtccgaccacagccac
aaggagctgagcgctgccgaggtgctgcacatcttcgaggatacctacctcaaccgtgca
aagccgctgaatgtggtggaagcccactttgcgcaggtaaacggcattaccgccacagtc
acgctggagctgaacggccagcgcaaggtggtcacctcggtgggcaacggccgtctggat
gccgtagccaacgccatccagagcgccaccggcatggacttccatctggaaaactactct
gagcacagtctggacgagggctccacctcccgcgcagcctcctatgtggggcttgtctgg
ggagacaacacggtcacatggggtgccggtaccgacaccgacattatcgtggccggtatc
cgcgcccttgtcagcgcaatcaacaatcgataa
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