Flavonifractor plautii: A4U99_08620
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Entry
A4U99_08620 CDS
T04429
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fpla
Flavonifractor plautii
Pathway
fpla00300
Lysine biosynthesis
fpla00550
Peptidoglycan biosynthesis
fpla01100
Metabolic pathways
fpla01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fpla00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A4U99_08620
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A4U99_08620
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A4U99_08620
Enzymes [BR:
fpla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A4U99_08620
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ANU41128
UniProt:
A0AAX1KJN7
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All DBs
Position
1791546..1792937
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AA seq
463 aa
AA seq
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MEPMTIREIMDAVGGKLLGEFGDINRMVGRVETDSRTIHAGSLFVPLVGERFDGHAYINA
ALEGGAAGCFTQRERESYLPGKFYIKVDSTQRALRDLAKYYKKKFPIPVVALTGSVGKTT
TKDMVAAVLGEKYRVLKTEGNLNNEIGVPMTLLRLSGEHEIAVLELGMNHAGEIDYLSAL
VEPDVVLMTNIGDSHIEHFGSREKILEAKSEIFHHVKSGAFVVINGDDPLLNTLPGKLPY
AFTRVGAGEGLDYRAEGLVSDGKSHMTCEVKTPHNSFPVEIPALGDHMIYPTLMAAAVGE
HFGLTQTQIADGVLHFAPTKMRMNLLHRGDDITILNDTYNANPQSMRAAVEVLSSARGAY
KVAVLGDMFELGPLAPALHAGVGDYLGKAGIDCLVAVGELARHIHDAAQAAGVPECYYCP
TKAEARPVLDGVVRPHATILVKASRGMALEELVDYLLTITGEA
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggagccgatgaccatacgtgaaatcatggacgcggtcggcggtaagctgctgggagag
tttggggatatcaaccggatggtgggacgggtggagacggacagccgcaccatccacgcc
gggtccctctttgtgcccctggtaggggagcggttcgacggccacgcctacatcaacgcc
gccctggaggggggcgctgcgggctgctttacccagcgggagcgggagagctatctgccg
ggcaagttctatatcaaggtggactccacccagcgggccctgcgggatctggccaagtat
tacaagaaaaagttccccatacctgtggtggccctgacgggctcggtgggtaagaccacc
accaaggacatggtggcggcggtgctgggggagaagtaccgggtgctcaagaccgagggc
aacctgaacaacgagatcggcgtgcccatgaccctgttgcgcctcagcggggagcacgaa
attgccgtgctggagctgggcatgaaccacgccggggagatcgactacctctccgccctg
gtggagcccgacgtggtgctgatgaccaacatcggcgactcccacatcgagcacttcggc
tcccgggaaaagatcctggaggccaagagcgagatcttccaccatgtcaagtccggcgcc
ttcgtggttatcaatggggacgatcccttgctgaacaccctgccggggaagctcccctat
gcgttcacccgcgtgggcgccggagaggggctggactaccgggcggaggggctggtcagc
gacggcaagagccatatgacctgtgaagtgaaaacgcctcacaactcttttccggtggag
atccccgccctgggcgaccacatgatctaccccacgctgatggcggcggcagtgggggag
cactttggcctgacgcagacgcagattgccgacggcgtgctccactttgcccccaccaaa
atgcgtatgaacctgctccaccggggcgatgacatcaccatcctaaacgacacctacaac
gccaacccccagtccatgcgggcggcggtggaggtgctctccagtgcccggggagcgtat
aaggtagccgtactgggcgacatgtttgagctggggcccctggcccccgccctccacgcc
ggcgtgggcgactacctgggcaaggcgggcatcgactgcctggtggcggtgggcgagctg
gcaaggcacatccatgacgcggcccaggccgccggcgtgccggagtgctattattgcccc
acaaaggcggaggccaggccggtgctggacggcgtggtgcggccccatgccaccattctg
gtcaaggcctcccgcggcatggcgctggaggagctggtggattacctgctcaccatcaca
ggggaggcgtaa
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