Faecalibacterium duncaniae A2165: CG447_12450
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Entry
CG447_12450 CDS
T06780
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
fpra
Faecalibacterium duncaniae A2165
Pathway
fpra00290
Valine, leucine and isoleucine biosynthesis
fpra00660
C5-Branched dibasic acid metabolism
fpra01100
Metabolic pathways
fpra01110
Biosynthesis of secondary metabolites
fpra01210
2-Oxocarboxylic acid metabolism
fpra01230
Biosynthesis of amino acids
Module
fpra_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
fpra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CG447_12450 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CG447_12450 (leuC)
Enzymes [BR:
fpra01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CG447_12450 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CG447_12450 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ATP00647
UniProt:
A0A2A7BFZ2
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Position
2521477..2522736
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AA seq
419 aa
AA seq
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MGMTLTQKILAAHAGLPEVKAGQLINAKLDIVLGNDITTPVAINEFEKAGFDGVFDKEHI
AIVLDHFVPNKDIKSATQSKQCREFANKYDILNFYDVGQMGVEHALLPEKGIVTAGDCII
GADSHTCTYGALGAFSTGVGSTDMAAGMATGMAWFKVPSAIKFVLKGKFSPRVSGKDLIL
HIIGMIGVDGALYKSMEFTGPGVASLTMEDRLCVCNMAIEAGAKNGIFPVDEVTRAYLNG
RSQRTPVYYEADPDAEYEKTIEIDLDKLEPTVSYPHLPENTHPASEGKDIRIDQVVIGSC
TNGRLEDMEAAYNILKGKHIAKGVRGIIIPATMAVYKECILRGWTEAFIDAGCIVSTPTC
GPCLGGYMGILAEGERCVSTTNRNFVGRMGHVKSEVYLASPATAAASALTGYITDPRTV
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgactctgacgcagaaaattctggccgcacatgcgggtttgccggaggtcaag
gcaggccagctcatcaatgccaagctcgatatcgtgctgggcaacgatatcaccaccccg
gtcgccatcaacgagtttgagaaggcaggctttgacggcgtgttcgacaaggagcacatt
gctatcgtgctggatcacttcgtccccaataaggacatcaagagcgcaacccagtccaag
cagtgccgcgagtttgccaacaaatatgatatcctcaacttctacgatgtgggtcagatg
ggtgttgagcacgccctcctgcccgaaaaaggcatcgtgaccgccggtgactgcatcatc
ggtgccgacagccacacctgcacctacggtgcactgggcgcattctccaccggtgtgggc
tccaccgatatggccgccggtatggccaccggaatggcatggttcaaggtgccctctgcc
atcaagtttgtgctcaagggcaagttcagccctcgcgtatccggcaaggacctgatcctg
cacatcatcggcatgatcggtgtggacggcgcactgtacaagtccatggaattcaccggc
ccgggcgtggcttccctgaccatggaggatcgcctctgcgtctgcaatatggccattgaa
gccggtgccaagaacggcatcttccctgtggacgaggtcaccagagcgtatctgaacggc
cgcagccagcgcactccggtctactacgaggctgacccggatgccgaatacgaaaagacc
atcgagatcgacctggacaagctggagcccacggtcagctaccctcatctgccggagaac
acccatcccgccagcgagggaaaggacatccggatcgatcaggtggtcatcggcagctgc
accaatggccgtctggaggatatggaggccgcttacaacatcctcaagggcaagcacatc
gccaagggcgtgcggggcatcattatcccggccaccatggcggtttataaggagtgcatc
ctgcgcggttggaccgaggcctttattgatgcgggctgcatcgtgtccacccccacctgc
ggtccctgcctgggcggctacatgggcatcctggccgagggggagcgctgtgtctccacc
accaaccgcaactttgtgggccgcatgggccatgtcaagagtgaagtctatctggcaagc
ccggccactgccgctgccagcgccctgaccggctatatcaccgacccccgcacggtctga
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