Pseudofrankia inefficax: FraEuI1c_2370
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Entry
FraEuI1c_2370 CDS
T01354
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fri
Pseudofrankia inefficax
Pathway
fri00300
Lysine biosynthesis
fri00550
Peptidoglycan biosynthesis
fri01100
Metabolic pathways
fri01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fri00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FraEuI1c_2370
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FraEuI1c_2370
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FraEuI1c_2370
Enzymes [BR:
fri01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FraEuI1c_2370
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6544
Knl-2-like_dom
Motif
Other DBs
NCBI-ProteinID:
ADP80409
UniProt:
E3J0C6
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All DBs
Position
2913687..2915168
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AA seq
493 aa
AA seq
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MIPLTLAEVAAATGGRLDGGADAATLVTAAVVDSRLVEPGALFVALPGARVDGHDFAAGA
VAAGARAVLAARPVSVPAVLVADPAGALMALAAHVRTLTKATVLAITGSSGKTTTKDLLA
DLLGSLGPTLAPPGSFNNEIGLPLTLLRLEPDTEYVALEMGARGIGHIAALCQVARPQVG
VVINVGSAHVGEYADGRAGIAQAKGELAEAATDVVVLNADDPLVAAMRPRAAGRRVVTFG
VAADADVRAERIALDAAGRASFDLVTDAERHRVALALVGEHQVGNALAAAAAALAVGMTP
TAAAAALAAARPRSRWRMEVTTAPSGLVVVNDAYNANPESMRAALRALVGLGADGGPDRR
RTWAVLGPMGELGTAAEAEHAELGRFAARLGVDRTVVIGEAARPLAQAAAGAGARVDWVA
DVDAAAELLATAALGDADVVLVKASRAAGLERVAAALTATGAAGPGAARGNGSTEAAESP
AAAGSTEAAEQTP
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgctgacgctcgccgaagtggccgcggccaccggcggcaggctcgacggcggc
gccgacgcggcgaccctcgtcacggccgcggtcgtcgactcccggctggtcgagcctggc
gcgctgttcgtcgcgctgccgggagcccgggtcgacggccacgacttcgccgccggcgcc
gtcgcggccggcgcgcgcgcggtgctcgccgcccgcccggtcagcgtccccgccgtgctg
gtcgccgaccccgccggcgcgctcatggcgctggccgcgcacgtccggacgctgacgaag
gcgaccgtgctggccatcaccggctcctcgggcaagacgacgaccaaggacctgctcgcc
gacctgctcgggtccctcgggccgacgctcgccccgccggggagcttcaacaacgagatc
ggcctgcccctgacgctgctgcggctggagccggacaccgagtacgtggcgctggagatg
ggcgcccggggcatcggccacatcgccgcgctctgccaggtcgcccggccccaggtgggg
gtcgtcatcaacgtcggcagcgcgcacgtcggcgagtacgccgacggccgggccggcatc
gcccaggccaagggtgagctggccgaggccgccaccgacgtcgtcgtgctgaacgccgac
gacccgctggtcgcggcgatgcgcccgcgcgccgccggccggcgggttgtcaccttcggc
gtcgccgcggacgcggacgtgcgggccgagcggatcgcgctcgacgcggccggccgggcg
tcgttcgacctggtcaccgacgccgagcgccaccgggtggccctcgccctggtcggcgag
caccaggtgggcaacgcgctggccgccgccgcggccgccctcgcggtcgggatgacgccc
acggccgccgccgccgcgctggcggcggcccggccgcgcagccgctggcggatggaggtc
acgaccgcgccgtccgggctggtcgtcgtcaacgacgcctacaacgccaaccccgagtcg
atgcgggccgcgctgcgcgccctggtcgggctcggcgccgacggcggtcctgaccggcgg
cggacctgggcggtgctgggcccgatgggtgagctcgggaccgcggccgaggccgagcac
gccgagctcggccggttcgccgcccggctgggcgtcgaccggacggtggtcatcggcgag
gcggcccggccgctcgcgcaggcggcggcgggggccggcgcgcgggtggactgggtcgcc
gacgtcgacgcggccgccgagctgctcgccacggcggcgctcggcgacgccgacgtcgtg
ctcgtgaaggccagccgcgcggccggcctggagcgggtcgcggcggcgctcacggcgacc
ggcgcggccggtcccggggccgcgagaggaaacggaagtacagaggcggccgaaagtccg
gcggcagcgggaagtacagaggcggcggaacagacgccgtga
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