Candidatus Protofrankia datiscae: FsymDg_3115
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Entry
FsymDg_3115 CDS
T01530
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fsy
Candidatus Protofrankia datiscae
Pathway
fsy00300
Lysine biosynthesis
fsy00550
Peptidoglycan biosynthesis
fsy01100
Metabolic pathways
fsy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fsy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FsymDg_3115
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FsymDg_3115
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FsymDg_3115
Enzymes [BR:
fsy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FsymDg_3115
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
FAD_binding_5
Motif
Other DBs
NCBI-ProteinID:
AEH10424
UniProt:
F8AYC1
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Position
complement(3701038..3702468)
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AA seq
476 aa
AA seq
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MMTLTLREVAVVCGGRLDAVDDHDAAVTGVVIDSRQVAAGALFVAVAGERVDGHDFAAAA
AGAGAVAVLAARPVGVPAVVVADPVAALAALAAQVRTRSSATVVAVTGSAGKTTTKDLLA
DLLGELGPTVAAAGSFNNEIGLPLTVTRIEPATRFAVLEMGARGPGHIAALCELARPRIG
VVLNVGSAHLGQYADGRAGIARAKGELAEAASDAVVLNADDPLVAGMAARARGEVITFGE
GERADVRAHDVRVGDDGRARFDLVAAGERHPVALTLVGEHQVGSALAAAAVAIRLGLPPA
RAAEALSRARARSRWRMEVAVTDTGVTVINDAYNANPESMRAALKTLVDLSRGRRAWAVL
GGMEELGASADDEHDALGRLVVRLGVEQLVAIGERARRIHLGASLEGSWSGESVWVADVE
QACTLLREQLVPGDVVLVKASRAFGLERVASELTSGAVSLGATPLDAAPGEWGAHG
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatgacgctgactctgcgcgaggtcgcggtggtctgcggcggccggctggacgccgtg
gatgatcatgacgccgccgtgaccggtgtcgtcatcgactcgcgccaggtcgccgccggc
gcgctgttcgtcgcggtggccggggaacgggtcgacggccacgacttcgccgccgcggcg
gcgggcgccggcgcggtcgcggtgctcgcggcccggccggtgggcgtgcccgcggtggtg
gtcgccgatccggtcgccgcgctggccgcgctcgccgcgcaggtgcgcacccggtcgtcg
gcgaccgtggtcgcggtgaccggttcggcgggcaagaccaccaccaaggacctgctcgcc
gacctgctcggcgaactcgggccgaccgtcgccgccgccggctcgttcaacaacgagatc
ggcctgccgctgaccgtcacgcgcatcgagccggccaccaggttcgccgtactggagatg
ggcgcccgcgggcccggccacatcgccgccctgtgcgagctggcccggccgcggatcggg
gtcgtgctcaacgtcggctcggcgcatctcggccagtacgccgacgggcgggccggtatc
gcgcgggccaagggcgaactggctgaggccgcctccgacgccgtcgtcctcaacgccgac
gacccgctggtcgccgggatggccgcccgtgcccgcggcgaggtgatcaccttcggtgag
ggggagcgggcggacgtgcgggcgcacgacgtgcgggtcggtgacgacggccgtgcccgc
ttcgacctggtggccgccggtgagcggcacccggtcgcactcactctcgtcggcgagcac
caggtcggcagcgcgctggccgccgccgcggtcgcgatccgcctcggcctgccgcccgcg
cgggcggccgaggcgctgtcgcgggcccgggcgcgcagccgctggcggatggaggtggcg
gtgaccgacaccggcgtcaccgtcatcaacgacgcctacaacgccaaccccgagtccatg
cgggccgcgttgaagaccctggtcgacctcagccggggccggcgggcctgggcggttctc
ggcggcatggaggaactcggcgcgagcgccgacgacgagcacgacgccctcggccggctc
gtcgtccgcctcggggtggagcagttggtggcgatcggcgagcgggcgcgccggatacat
ctcggggcgtcgctggaagggtcctggtcgggggagtcggtgtgggtcgccgacgtcgag
caggcgtgcacactgctgcgggaacagctggtaccgggcgatgtggtactggtcaaggca
tcccgcgcattcgggttggagcgggtcgcgagcgagttgacgtcgggtgctgtgtccctg
ggtgccacacctctggatgccgcgcccggcgagtggggtgcgcacgggtga
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