Francisella tularensis subsp. tularensis TIGB03: FTU_0476
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Entry
FTU_0476 CDS
T01762
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2 6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ftg
Francisella tularensis subsp. tularensis TIGB03
Pathway
ftg00300
Lysine biosynthesis
ftg00550
Peptidoglycan biosynthesis
ftg01100
Metabolic pathways
ftg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ftg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FTU_0476 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FTU_0476 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FTU_0476 (murF)
Enzymes [BR:
ftg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FTU_0476 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ACBP4_C
DUF7197
Motif
Other DBs
NCBI-ProteinID:
AFB78587
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Position
512249..513607
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AA seq
452 aa
AA seq
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MIKSLKQLAIQAGLEYLGEDVSIQTVAINSNEVRQDCLFVAIVANRDGHEFIPSAIANGA
KAILVSKKQGLDIPQVVCGNTIKGLRALAKEYRKSLTMPIISLTGSCGKTSVKEMIVTLL
GERKVHFTQGNLNNYLGVPMTILETPHDVDFAVIEAGTNVGGEIKAAADIIQPNIAMITN
VGACHLENLKTLDGVMIEKGELLKALPRDGFCIVNLDDERIPNYAKLLECKKISCSMTNP
KADILVLDYRATSNSYAFKIRIFSQEYDYQLPNIGKHNLFNSVLAIASVVAVGLEPKDFL
QNTQNIKNYKGRFSTEKLSDKLTLIDDTYNASAGAVQAAIEDLAEFDGKKILAISSMREL
GDEAENYHRKMGQWLKKANLDKIFLFGEKNLIDYVLAEYSNQNAKYYESKDELNNDLAKI
LDEYKSQSTKLTVKGARSFKMEEVVKFVKENL
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgataaaatcactaaaacaattagcaatccaagcaggcttagaatatttgggtgaagat
gtatcaatacaaacagtagctataaattcaaatgaagtaagacaagattgcttatttgtt
gcaattgtagctaatcgtgatggacacgagtttattccaagtgctattgctaatggcgct
aaagctattttagtttcaaaaaaacaaggtttagatattccacaagtagtttgtggcaat
actatcaaaggcttacgggctttagctaaagaatatcgcaaatcactaactatgccaata
atatctttaactgggagttgcggtaaaacatctgttaaagaaatgattgtaactcttctt
ggtgagagaaaagttcattttactcaaggtaacctaaataattatcttggtgtaccaatg
acaatattagaaacaccgcatgatgtcgattttgcagtgattgaggcaggtacaaatgtt
ggtggtgagataaaagctgcagctgatattatccaaccaaatatagcgatgattacaaat
gttggcgcttgccaccttgagaacctaaaaacgctggatggtgtaatgatagaaaaaggg
gagcttctcaaagctttgccaagagatggtttttgtatcgtaaatctagatgatgaaaga
attccaaattatgctaagctgctagagtgtaaaaagattagctgctcaatgactaatcca
aaagctgatattttagtattagattatagggcaacatcaaatagttatgcttttaagatt
agaatttttagccaagagtatgattatcaactaccaaacattggcaagcataatttgttt
aatagtgtcttggctattgctagtgtagttgctgtggggcttgagcctaaggatttctta
caaaatacacaaaatatcaaaaactataaaggtagattttcaactgaaaaactcagtgat
aaactaactcttatagatgatacatataatgcaagtgctggcgctgtgcaagctgcaatt
gaagatttggcagaatttgatggtaaaaaaatattggctattagttcaatgcgtgagcta
ggagatgaagctgaaaattatcatcgaaaaatggggcaatggcttaaaaaggcaaattta
gataagatatttttatttggtgagaaaaatttaatagattatgttttggcagaatattca
aaccagaatgctaaatattatgaatctaaagacgagctaaataatgatttagctaaaata
ttggatgaatataagtcacaaagtactaagctaacagtcaaaggggctagaagttttaag
atggaagaagttgtcaaatttgttaaggaaaacttataa
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