Francisella tularensis subsp. holarctica OSU18: FTH_0588
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Entry
FTH_0588 CDS
T00399
Name
(GenBank) isocitrate dehydrogenase (NADP(+))
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
fth
Francisella tularensis subsp. holarctica OSU18
Pathway
fth00020
Citrate cycle (TCA cycle)
fth00480
Glutathione metabolism
fth00720
Other carbon fixation pathways
fth01100
Metabolic pathways
fth01110
Biosynthesis of secondary metabolites
fth01120
Microbial metabolism in diverse environments
fth01200
Carbon metabolism
fth01210
2-Oxocarboxylic acid metabolism
fth01230
Biosynthesis of amino acids
fth04146
Peroxisome
Module
fth_M00009
Citrate cycle (TCA cycle, Krebs cycle)
fth_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
fth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
FTH_0588
09102 Energy metabolism
00720 Other carbon fixation pathways
FTH_0588
09106 Metabolism of other amino acids
00480 Glutathione metabolism
FTH_0588
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
FTH_0588
Enzymes [BR:
fth01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
FTH_0588
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Gene cluster
GFIT
Motif
Pfam:
IDH
Motif
Other DBs
NCBI-ProteinID:
ABI82553
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Position
573195..575438
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AA seq
747 aa
AA seq
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MKFYLQEIFMHKIFYTFTDEAPALATGSFLPIVESFTKVADIELETKDISLSARILANFN
DYLTAEQKCSDDLAILRELAKTPDANIIKLPNISASIPQLTAAIKELQSKGYKIPDYPYE
PKDDKEQEIKARYAKVLGSAVNPVLREGNSDRRVADAVKKYAEKHPHSMGEWTKDSKSHV
ASMSADDFYANEKSYIVPKATKVKIVHIDTKDTQTVLKDNLALEEKEIIDATKISIKALR
EFYKNEIAKAKKEGTLLSLHLKATMMKVSDPILFGHAVEIFFEDIFKKYAKEFKELGVNP
RNGWGDAVEKIKQLPQELQDKINADIEKVFAKQPDIAMVNSDKGITNLNVPSDVIIDASM
PAAIRSSGKMWNKDGKLQDMKAMIPDRCYAGVYAATIDFCKENGAFDVATMGDVSNVGLM
AKKAEEYGSHDKTFEIQADGKVEVIDAEGNVIFEHQVEKGDIWRACQTKDIAVKDWVKLV
VNRAKITQNPAIFWLDSKRAHDRNLIAKVNEYLTHHDTTGLDIQILSPVEATKYSLKRMK
EGKNTISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVEQL
IEENHLRWDSLGEFLALGASLEDLAIKTRDAKIKVLAETLSQANKDFLDNDKSPRRKVGE
LDTRGSHFYLAYYWVKALAEQTGNAELKAKFEPIYIELKANKDKIVKELNDAQGKKVDVG
GYYHMDKVKLDAVMRPSKTFNTILAQI
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
gtgaaattctatctacaggagatttttatgcataaaatattttatacatttacagatgaa
gcaccagcattggcaacaggatcatttttaccaatagttgagagctttactaaagttgca
gatatagagttagaaacgaaagatatttctctatcagcgcggatattggctaactttaat
gattaccttactgcagagcaaaagtgttctgatgatttagcgatacttagagagcttgca
aaaactccagatgctaatattataaaacttccaaatattagtgcatcaattcctcagctt
acagcagctattaaagaacttcagtcaaagggttataaaatacctgattatccatatgag
ccaaaagatgataaagagcaagaaattaaagcacgctatgcaaaagttttagggagtgcc
gtaaaccctgttttaagagagggtaactctgatcgtagagttgctgatgctgttaagaag
tacgccgagaaacatccacattctatgggtgaatggacaaaagactctaaatctcatgtg
gcaagtatgagtgctgatgacttttatgctaatgagaaatcttatattgtaccaaaagca
actaaggttaaaatagtccatatagatacaaaagacactcaaactgtgcttaaagataat
cttgcgctagaagaaaaagaaattattgatgctactaagatatctataaaagctttaaga
gaattctacaaaaatgaaatagctaaggctaaaaaagaaggtacgctattatccctccac
ctaaaagctacgatgatgaaagtttctgatccaatattgtttggtcatgcggtagagatc
tttttcgaagatattttcaaaaagtatgctaaagagtttaaagagttaggtgtaaatcct
cgtaatggttggggtgatgcagtagagaaaatcaagcaacttccacaagaacttcaagat
aaaattaatgccgatattgaaaaagtatttgcaaagcagcctgatattgcgatggttaat
tctgacaagggtattacaaacctaaatgttccgagtgatgtaattattgatgcttctatg
cctgcggctattcgttcatctggtaagatgtggaacaaagatggcaaacttcaagatatg
aaagcgatgattcctgatagatgttatgctggagtgtatgcggcaactatcgatttctgt
aaagaaaatggcgcttttgatgtggctactatgggtgatgtttctaacgttggtctgatg
gcgaaaaaagcagaagagtatggttctcatgataagacatttgaaatccaagctgatggt
aaagttgaagttattgatgctgaaggtaatgtaatatttgagcatcaagtcgaaaaaggc
gatatttggcgtgcttgtcaaactaaagatatcgcagttaaagactgggttaaactagtt
gttaatagagctaaaattactcaaaatcctgcgattttttggttggattcaaaaagagct
catgatagaaacctaattgctaaagtgaatgagtatttaactcatcatgatactactggc
ttagatattcaaatattatctccagtagaagctacgaaatactctctaaaaagaatgaaa
gagggtaaaaatacaatttctgtgacaggtaacgttttaagagattacttgacagattta
tttcctattttagagcttggtacttctgctaagatgctttctatagttccgctattagct
ggaggtggattatttgaaactggggctggtggttctgcgcctaaacacgttgagcaactt
attgaggaaaatcacctaagatgggattctttaggtgagtttttggctttaggagcatca
ttagaagacttagctatcaaaactagagatgctaaaatcaaggttttagctgagacatta
tcacaggcaaacaaagatttcttggataatgataaatcgccgcgtcgtaaagttggtgag
cttgatactcgaggaagtcatttctatttggcttactattgggttaaggctctagctgag
caaacaggtaatgctgaattaaaagctaaatttgagccaatttatattgaactaaaagct
aataaggataaaattgtcaaagagcttaatgatgctcaaggcaaaaaagttgatgttggt
ggctactatcatatggataaagtaaaattagatgcagtgatgaggccgagtaaaactttt
aatacaattttggcgcaaatataa
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