Francisella tularensis subsp. holarctica OSU18: FTH_1276
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Entry
FTH_1276 CDS
T00399
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase
KO
K01919
glutamate---cysteine ligase [EC:
6.3.2.2
]
Organism
fth
Francisella tularensis subsp. holarctica OSU18
Pathway
fth00270
Cysteine and methionine metabolism
fth00340
Histidine metabolism
fth00480
Glutathione metabolism
fth01100
Metabolic pathways
fth01110
Biosynthesis of secondary metabolites
fth01240
Biosynthesis of cofactors
Module
fth_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
fth00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FTH_1276 (gshA)
00340 Histidine metabolism
FTH_1276 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
FTH_1276 (gshA)
Enzymes [BR:
fth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
FTH_1276 (gshA)
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Ortholog
Paralog
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
ABI83124
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Position
complement(1244565..1246070)
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AA seq
501 aa
AA seq
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MYDFKKINNLRGIERETLRVTDCGNLVTSNHPDGLGHKLTNNSITVDFSENLLELITKPH
DSIDKAIGELYQLSAFTLDNMHNDEIILNTSMPLSANDNDIQEADFGSSNSGRMKRVYRK
GLSARYGKIMQIISGIHYNFSFDKDLISNIATNKQVSISDIYFDVLNNYFEFMWLLPYLF
GASPICAKTSVKNKPDYLLVLDDKFYVGEYATSLRMSDLGYTSPAQKDLAISYDNVKAYV
KDLIQATDDTFADYKRIGLYNSQGQRIQLNDSILQIENEYYSAIRPKQIAKRGERPACAL
YNRGVEYVEVRVLDVDPFEPVGISKDTALFVEAMLMTCLDKDAKKYHKDIIKQAKQNLTA
VAIQGRNPQLKLKKLDDDSEILLKDYALELFDEIEAVAKKMPKEYLDAVEIQKRKVLDIS
QTPSAKIIELARQHGYKKFILDISRQVSQQFRSYELPAAIVAKLKDQAGQSVAAEKELVA
NDKISLDEYINRYYESSKGCC
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgtacgatttcaaaaaaataaataacctacgcgggatagaaagagaaactttaagagtt
actgattgtggtaatctagtaacttctaatcaccctgatggtttaggacataagttgact
aataatagtattaccgttgatttctctgaaaatttgcttgagctgataactaaaccgcat
gatagtatagataaagcaatcggtgagctatatcaactttcggcatttactttggataat
atgcacaatgatgaaattatccttaatactagtatgccactatctgctaacgataatgat
atacaggaagcagattttgggagttcaaattcggggcgaatgaagcgtgtttaccgtaaa
gggctatctgcgcgatatggtaaaattatgcagataatttccgggatacattataatttt
tcttttgataaagacttaattagtaatattgctactaacaagcaagtatcaatatcagat
atttattttgatgtgcttaataactattttgagtttatgtggcttttaccgtatcttttt
ggcgctagtcctatatgtgctaagacttctgttaaaaataaacctgattatttattagtt
ttagatgataagttttatgttggtgaatacgctacaagcttgagaatgagtgaccttggc
tacacaagtcccgcacaaaaagatttagcaatatcatatgataacgttaaggcatatgtt
aaagatttaattcaagcaactgatgatacttttgctgattataagcgtataggcctttat
aattctcaagggcaaagaatacagttaaatgatagtattttacagatagaaaatgaatat
tacagcgcaattagacctaagcaaattgctaaaagaggagagagacctgcttgtgcatta
tataaccgtggtgttgagtatgttgaggttagagttcttgatgtcgatccatttgagccg
gtgggtataagcaaagatacagcgctttttgttgaggcgatgttgatgacttgtctagac
aaggatgctaaaaaatatcataaagatattatcaaacaggcaaaacaaaatttaactgca
gttgcaatacagggacgtaatccacaacttaagcttaaaaagcttgatgatgatagtgaa
atacttttaaaagattatgctttagaattgtttgatgaaattgaggctgtagctaagaaa
atgcctaaagaatacttagatgctgttgaaattcaaaagcgcaaagtattagatatatcg
caaacaccttcagctaaaataatagaattagctagacaacatggttataaaaaatttatc
ttagatatatctcgccaagtatcacaacaattcagaagttatgagcttccagcagcaatt
gtagctaaattaaaagaccaagctggccaatctgttgctgcagaaaaagaattagttgct
aatgataaaatttccttagatgaatatatcaatagatattatgaatcttcaaagggttgt
tgttag
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