Francisella tularensis subsp. holarctica FSC200: FTS_0494
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Entry
FTS_0494 CDS
T02350
Symbol
murF
Name
(GenBank) UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fti
Francisella tularensis subsp. holarctica FSC200
Pathway
fti00300
Lysine biosynthesis
fti00550
Peptidoglycan biosynthesis
fti01100
Metabolic pathways
fti01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fti00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FTS_0494 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FTS_0494 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FTS_0494 (murF)
Enzymes [BR:
fti01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FTS_0494 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ACBP4_C
DUF7197
Motif
Other DBs
NCBI-ProteinID:
AFT92420
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Position
479659..481017
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AA seq
452 aa
AA seq
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MIKSLKQLAIQAGLEYLGEDVSIQTVAINSNEVRQDCLFVTIVANRDGHEFIPSAIANGA
KAILVSKKQGLDIPQVVCGNTIKGLRTLAKEYRKSLTMPIISLTGSCGKTSVKEMIVTLL
GERKVHFTQGNLNNYLGVPMTILETPHDVDFAVIEAGTNVGGEIKAAADIIQPNIAMITN
VGACHLENLKTLDGVMIEKGELLKALPRDGFCIVNLDDERIPNYAKLLECKKISCSMTNP
KADILVLDYRATSNSYAFKIRIFSQEYDYQLPNIGKHNLFNSVLAIASVVAVGLEPKDFL
QNTQNIKNYKGRFSTEKLSDKLTLIDDTYNASAGAVQAAIEDLAEFDGKKILAISSMREL
GDEAENYHRKMGQWLKKANLDKIFLFGEKNLLDYVLAEYSNQNAKYYESKDELNNDLAKI
LDEYKSQSIKLTVKGARSFKMEEVVKFVKENL
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgataaaatcactaaaacaattagcaatccaagcaggcttagaatatttgggtgaagat
gtatcaatacaaacagtagctataaattcaaatgaagtaagacaagattgcttatttgtt
acaattgtagctaatcgtgatggacacgagtttattccaagtgctattgctaatggcgct
aaagctattttagtttcaaaaaaacaaggtttagatattccacaagtagtttgtggcaat
actatcaaaggcttacggactttagctaaagaatatcgcaaatcactaactatgccaata
atatctttaactgggagttgcggtaaaacatctgttaaagaaatgattgtaactcttctt
ggtgagagaaaagttcattttactcaaggtaacctaaataattatcttggtgtaccaatg
acaatattagaaacaccgcatgatgtcgattttgcagtgattgaggcaggtacaaatgtt
ggtggtgagataaaagctgcagctgatattatccaaccaaatatagcgatgattacaaat
gttggcgcttgccaccttgagaacctaaaaacgctggatggtgtaatgatagaaaaaggg
gagcttctcaaagctttgccaagagatggtttttgtatcgtaaatctagatgatgaaaga
attccaaattatgctaagctgctagagtgtaaaaagattagctgctcaatgactaatcca
aaagctgatattttagtattagattatagggcaacatcaaatagttatgcttttaagatt
agaatttttagccaagagtatgattatcaactaccaaacattggcaagcataatttgttt
aatagtgtcttggctattgctagtgtagttgctgtggggcttgagcctaaggatttctta
caaaatacacaaaatatcaaaaactataaaggtagattttcaactgaaaaactcagtgat
aaactaactcttatagatgatacatataatgcaagtgctggcgctgtgcaagctgcaatt
gaagatttggcagaatttgatggtaaaaaaatattggctattagttcaatgcgtgagcta
ggagatgaagctgaaaattatcatcgaaaaatggggcaatggcttaaaaaggcaaattta
gataagatatttttatttggtgagaaaaatttactagattatgttttggcagaatattca
aaccagaatgctaaatattatgaatctaaagacgagctaaataatgatttagctaaaata
ttggatgaatataagtcacaaagtattaagctaacagtcaaaggggctagaagttttaag
atggaagaagttgtcaaatttgttaaggaaaacttataa
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