Francisella tularensis subsp. mediasiatica FSC147: FTM_0152
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Entry
FTM_0152 CDS
T00698
Symbol
acnA
Name
(GenBank) aconitate hydratase 1
KO
K27802
aconitate hydratase A / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ftm
Francisella tularensis subsp. mediasiatica FSC147
Pathway
ftm00020
Citrate cycle (TCA cycle)
ftm00630
Glyoxylate and dicarboxylate metabolism
ftm00640
Propanoate metabolism
ftm00720
Other carbon fixation pathways
ftm01100
Metabolic pathways
ftm01120
Microbial metabolism in diverse environments
ftm01200
Carbon metabolism
ftm01210
2-Oxocarboxylic acid metabolism
ftm01230
Biosynthesis of amino acids
Module
ftm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ftm_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ftm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
FTM_0152 (acnA)
00630 Glyoxylate and dicarboxylate metabolism
FTM_0152 (acnA)
00640 Propanoate metabolism
FTM_0152 (acnA)
09102 Energy metabolism
00720 Other carbon fixation pathways
FTM_0152 (acnA)
Enzymes [BR:
ftm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
FTM_0152 (acnA)
4.2.1.99 2-methylisocitrate dehydratase
FTM_0152 (acnA)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Aconitase_C
TyeA
Motif
Other DBs
NCBI-ProteinID:
ACD30247
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Position
160613..163426
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AA seq
937 aa
AA seq
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MSDIKNITKLQIEDKGKKYSLYSLKKLSQELGKDVTRLPYSIRVLLENQLRNIDGYKVKE
DDMHKVLDWDAKASSRPEIPHMPARVVMQDFTGVPAVVDLAAMRKAIKDAGGDADKINPL
VDTAMVIDHSVQVDFYGTKTALAQNVAKEFERNGERYSLLKWAQKAFDDFIVVPPGMGII
HQVNLEYLAKGALVKNINGEDVIYPDTLVGTDSHTTMINGVGVVGWGVGGIEAEAVMLGQ
PYYMVLPDVVGVKFTGKLKTGVTATDLVLKVTEVLRKHGVVGKFVEYYGEGLESLSLPDR
ATIANMAPEYGATIGFFPVDEVTLDFFNNTNRSELVDAAREMYKEQLLFRENPAEEPEYS
GIVEIDLSEVESNLAGPKRPQDRVAFHDMKKAFAEALVHEQGLHGFGLTDEQLQKSAEVK
GLNERITHGSVAIAAITSCTNTSNPSLLLGAGLLAKKANEKGLKVKPFVKTSLAPGSQVV
TQYLEKANLLPELENLGFNLVGYGCTTCIGNSGPLDEPVVEAINEADLIVASVSSGNRNF
EGRINPHVKANYLASPIHVVAYALAGTVDFDPVEDAIGKDAEGNDVYLADIWPTTEEIAA
IQSHVINSDMFKKAYATVLDGTEDWQKLKAPEGKLYEFDSSSTYIQCPNFFEKFAEGNDD
LDIKGARTLLMLGDSVTTDHISPAGAIPEEYPAGQYLKSHGVEKKDFNSYGSRRGNHEVM
MRGTFANIRIRNLLLDNVEGGFTKYHLDGSQQYVFDAAMKYKEKGIPLVILAGKEYGTGS
SRDWAAKGTFLLGVKAVIAESYERIHRSNLVGMGVLPLEYVNGQNAKTLGLDGTEMFNIK
NLNNIKPRQIVIVEAVHPKTAHTTTFEALARLDADVDVDYLKNGGILQTVLKDIMGDKKE
SKSTQSTTSKGCGSADTSSETSCPFAKIANFFKKLFK
NT seq
2814 nt
NT seq
+upstream
nt +downstream
nt
atgtctgatattaaaaatatcactaagctacaaatagaggataaaggaaagaaatattct
ctatatagcttaaagaaactttctcaagagcttggtaaagatgttacgcgtcttccttat
tcaatcagagtattacttgaaaaccaacttagaaatatagatggttataaagtaaaagaa
gatgatatgcacaaggttttagattgggacgctaaagctagctcaagacctgagatccca
catatgcctgctagggttgtgatgcaagatttcacaggtgtaccagcagttgtggattta
gctgcgatgagaaaggcgatcaaagatgctgggggtgacgcagacaaaattaaccctctt
gtagatacagcaatggtaattgaccactcagtacaggttgatttttatggaacaaaaact
gctttagctcaaaacgtagctaaagaatttgaaagaaatggtgagagatacagcttgctt
aagtgggcacaaaaagcatttgatgattttattgttgtaccacctgggatgggtattatc
caccaagttaatttagagtaccttgcaaaaggcgctttagttaagaatattaatggtgaa
gatgtaatttatccagatactctagtaggtacagattcacacactactatgatcaatggt
gttggtgtagttggttggggtgtcggtggtattgaggctgaagctgtaatgcttggtcaa
ccatactatatggttttacctgatgttgttggtgtgaaatttactggtaagctaaaaact
ggtgtaacagctactgaccttgtacttaaagttacagaagtgcttagaaagcatggtgtt
gttggcaagtttgttgagtactatggcgaaggtttagagagcttatctttaccagataga
gcaactatcgcaaacatggctccagaatatggtgcaacaataggtttcttcccagttgat
gaagtaacattagacttcttcaacaatacaaaccgtagtgagttagttgatgccgcgcgt
gaaatgtataaagaacaattgctatttagagagaatccagctgaagagccagaatattct
ggtatagtagaaatagatctatcagaagttgaatctaaccttgctggtcctaagcgtcca
caagatagagttgcattccatgatatgaaaaaagcttttgcagaagctttggtacatgag
caaggattacatggttttggcttaactgacgagcaattacaaaaatcagctgaagtaaaa
ggtcttaatgaaagaattactcacggttcagttgctattgctgcaattacttcatgtaca
aatacttctaatccatcactgcttttaggtgctggtttattagctaagaaggcaaatgag
aaaggcttaaaagttaagccttttgttaaaacatcattagcaccaggatctcaagttgta
actcaataccttgagaaagctaatttattaccagagcttgagaacttaggcttcaacctt
gttggttatggttgtacaacttgtatcggtaactctggtcctttagatgagcctgtagta
gaggctattaacgaggctgatcttatagtggcttctgtaagttcaggtaaccgtaacttt
gaaggtcgtattaatcctcatgttaaggcaaattaccttgcatcaccaattcatgtggtt
gcttatgcattagctggaactgttgattttgatccagttgaggatgctattggtaaggat
gcagagggtaatgatgtttaccttgctgatatttggccaactacagaggaaattgctgct
attcaatctcatgtaattaactctgatatgtttaaaaaggcttatgcaacagttcttgat
ggtactgaggactggcaaaaacttaaagctcctgaaggtaagctgtatgagtttgatagt
tcttctacttatatccaatgtcctaacttctttgagaagtttgcagaaggtaatgatgat
ttagatatcaaaggtgctagaactcttttaatgttaggtgattctgtaactacagaccat
atttcacctgctggagctattccagaagagtaccctgctggacagtatctaaaatctcat
ggggttgaaaagaaagattttaactcttatggttctcgtcgtggtaaccatgaagttatg
atgagaggtacttttgctaatatccgtatccgtaacttacttttagacaatgtcgaaggt
ggctttactaagtatcaccttgatggatctcaacagtatgtatttgatgctgctatgaaa
tataaagaaaaaggtattccattagttatattagcaggtaaagagtatggtactggttct
tcacgtgactgggctgcaaaaggtacattcctattaggcgtgaaagcagttatcgcagag
agctatgaaagaattcatagatctaacttagttggtatgggtgtattaccacttgagtat
gtaaatggacagaatgctaagactttaggtttagatggtaccgaaatgtttaatattaag
aacttaaacaatatcaaaccgcgtcaaatagttattgtagaggcagtacatcctaagact
gcacatactacaacatttgaagcattagctcgtttagatgctgatgttgatgttgattac
ttgaagaatggcggtatcttacaaactgttcttaaagacattatgggcgataaaaaagaa
tctaagtctacgcaatcaactactagtaaaggttgtggtagtgcagatacttcttctgag
acatcttgtccatttgcaaagattgctaatttcttcaagaaactatttaagtaa
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