Francisella tularensis subsp. mediasiatica FSC147: FTM_0581
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Entry
FTM_0581 CDS
T00698
Symbol
thrA
Name
(GenBank) aspartate kinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ftm
Francisella tularensis subsp. mediasiatica FSC147
Pathway
ftm00260
Glycine, serine and threonine metabolism
ftm00270
Cysteine and methionine metabolism
ftm00300
Lysine biosynthesis
ftm01100
Metabolic pathways
ftm01110
Biosynthesis of secondary metabolites
ftm01120
Microbial metabolism in diverse environments
ftm01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
ftm00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FTM_0581 (thrA)
00270 Cysteine and methionine metabolism
FTM_0581 (thrA)
00300 Lysine biosynthesis
FTM_0581 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FTM_0581 (thrA)
Enzymes [BR:
ftm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FTM_0581 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FTM_0581 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
NAD_binding_3
ACT
Sacchrp_dh_NADP
GFO_IDH_MocA
DapB_N
F420_oxidored
Sulfotransfer_4
Peptidase_C10
Hormone_2
DUF5427
Motif
Other DBs
NCBI-ProteinID:
ACD30581
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Position
641682..644102
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AA seq
806 aa
AA seq
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MIVHKFGGSSLATAEKIKNVSNIINCKDEAVVVSASAKTTRNLQKTIDQATIAQDYSKTL
EQIYEHHNEIIKQLIPNDETLRTLIVTDLANIKHILSTITITGFCADSLRFFILGFGEIW
SARILTTYLKSKGKKAAFIDASECLIVNDRSYPVTVDWQQSLEKLEIIKSDTPADVYVIT
GFIAQNKYGKRTILSLNCSDYSAAIFAKLLQANKLYIWTDVAGVYSANPQVVPEAKPLTQ
LTYKEALELAYFGASVVHPLTIAPMALDRTPIYIKSSYTPDEVGTKISADKDENQGIIKG
LTSVSDVAIVRVQGAGMIGVSGISFKVFGALEKANVSVMMISQASSEYSICFAIDNLDVD
KATEALRQEFANDIKNNLIEEIIVHKHYSLITAVGEGMKSKTGSLAKLVNSLKLANINIH
AIAQGSSERSVTFAVKAEDEVRGVQAMHRHYNSVSDDIAIAVIGAGNIGKAFIRQLKQTY
EKWYAKGINLVLISATNSKKMRFSYENLLFENINSLLEKNTEQINLEKLAEFMSHASATK
KIVIDATASESVSKNYISFLQKGISVITPNKYANSGNYEFYQELRKVAKQNGTSFLYETN
VCAGLPLIVTLQNMVQSGDHVRTIKGIFSGTLSYLFTQLNNGVVFSDAVKMAYDAGYTEP
DPRQDLSGMDVARKTVILAREIGLNIGLNDLVIENLVPEELRECSVEEFFAKLPAFNEQI
MQQIADKKKNLAGVHYVGSIVNGTANVGIQAYDESSPFANVKGTDNIVMINTDRYTQPMV
IQGAGAGVEVTAAGVYADVITVIRER
NT seq
2421 nt
NT seq
+upstream
nt +downstream
nt
atgatagtgcataagtttggtgggagtagccttgctactgcagaaaaaataaaaaatgtt
tctaatattataaactgtaaagatgaagctgtagtagtttcagcttctgcaaaaactaca
agaaatctacaaaaaactatagatcaagctacaatagcccaagattacagcaaaactcta
gagcaaatctatgagcatcataatgaaattattaagcaattaattccgaatgatgaaact
ctaagaactttgattgttacagatttagctaatatcaagcatattttaagtaccatcact
attacaggtttttgtgcagatagtttaaggttttttattttaggttttggtgaaatttgg
tcagctaggattctaacaacttatttgaagtccaaggggaaaaaggcggcttttatagat
gcatcagaatgtttgattgtcaatgatcgtagttaccctgtaacagttgattggcaacaa
agtttagaaaagttagaaattatcaaaagtgatactcctgcagatgtatatgttataaca
ggatttatcgcacagaataaatatggtaaaagaactattcttagtttgaattgtagtgac
tattctgcagctatttttgcaaaattattacaagctaataagttgtatatttggactgat
gttgctggtgtatatagtgctaatccacaagttgtaccagaggcaaagcctctaactcaa
ttaacatataaagaggctctagagttagcatactttggagcatctgtggttcatccgctt
acaatagcacctatggctttagataggacgccaatatatataaaaagtagttatacgcca
gatgaagttggtacaaagataagtgcagataaagatgagaatcaaggaattatcaagggt
ttaacaagtgtatcagacgttgctattgttcgagttcaaggtgctggaatgataggagta
tcaggtatatcgtttaaggtattcggtgcgctagaaaaagctaatgtttcagtgatgatg
atatcccaggcaagttctgaatactcgatatgttttgctatagataaccttgatgttgat
aaagcaacagaggcactcagacaagagtttgcaaatgacataaaaaataacttaatagaa
gaaataattgtccataagcactattcgctaattacagcagttggtgagggtatgaagtct
aagactggctcgctagcaaaactagtcaattctcttaagttagcaaatataaatatacat
gcaattgctcaaggttcatcggagagaagtgtgacatttgctgtaaaagcagaggatgaa
gttcgaggtgtacaagcaatgcatcgtcattataattctgtaagtgatgatattgcaatt
gcggtaatcggtgctggtaatattggtaaagctttcatcagacagcttaagcagacttat
gaaaaatggtatgcaaaaggtattaatttggtattgataagtgctactaattcaaaaaag
atgagattttcttatgaaaatttattatttgaaaatataaatagtttacttgagaaaaat
acagaacaaattaatctagagaaacttgctgaatttatgtcgcatgcctcagctactaaa
aaaattgttatcgatgccactgcaagtgaaagtgtatcaaaaaactatattagtttctta
caaaaaggaataagtgtaattacgccaaataaatatgcaaactcaggtaattatgagttc
taccaagaacttagaaaagtcgctaaacaaaatggcactagctttttgtatgaaacaaat
gtttgtgctggccttcctctcatagtcacattacaaaacatggttcaaagtggtgatcat
gttagaactatcaaagggattttctcagggactttgagctatttgtttacacaattaaat
aatggtgtagttttttctgatgcagttaagatggcgtatgatgcaggatatacagagcca
gatccaagacaagatttatcgggtatggatgtggcgagaaagactgtaattttggctaga
gagataggtctaaatataggtctaaatgatttagttattgaaaatttagtaccagaagaa
ttaagagagtgtagtgtagaagagttttttgctaaacttcctgcatttaacgagcaaatt
atgcaacaaattgctgataaaaagaaaaatttagcaggcgtacattatgttggatctata
gtaaacggtactgcaaatgtcggtatccaagcttatgatgagtctagtccttttgcaaat
gtgaaaggtacagataatatcgtgatgataaatacagatagatatactcagcctatggtt
atccaaggtgctggtgcgggtgttgaggttacagcagcaggtgtatatgctgatgttata
actgtgataagagaaagatag
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