Francisella tularensis subsp. novicida U112: FTN_0059
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Entry
FTN_0059 CDS
T00432
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
ftn
Francisella tularensis subsp. novicida U112
Pathway
ftn00290
Valine, leucine and isoleucine biosynthesis
ftn00660
C5-Branched dibasic acid metabolism
ftn01100
Metabolic pathways
ftn01110
Biosynthesis of secondary metabolites
ftn01210
2-Oxocarboxylic acid metabolism
ftn01230
Biosynthesis of amino acids
Module
ftn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ftn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FTN_0059 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FTN_0059 (leuB)
Enzymes [BR:
ftn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
FTN_0059 (leuB)
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Motif
Pfam:
Iso_dh
DUF6259
Motif
Other DBs
NCBI-ProteinID:
ABK88970
UniProt:
A0Q405
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Position
complement(69704..70783)
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AA seq
359 aa
AA seq
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MEKNIAILAGDGIGPEVMESAIKVLDTIAKKYNHKFNYIEALIGGAAYVKYKSHCPEETL
EICKNSDAILFGSVGGPVEAQNEEKWQGCEANSILALRKHFGFNINIRPSKIFPALREAC
PLKDSRIANGADIEIFRELSRDIYFGEHRTFTDEHGVKCATDIAEYDEHTIRNIVVQAFE
RATQRSNRLTSVDKANVLDTSRLWRNIVNEVAKDYPSVKVNHMYVDNCAMQMVLNPSQFD
VMVTGNLFGDIISDLASVLPGSIGLVPSISLNKDGFGLYEPSGGSAYDIKGQGKANPIAQ
ILSASLMLSYSFGLVTEAEAIASAINKTLEDGFRTQDIYTQGTKLASTKEFTNEIIKNL
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaaaatattgctatattagcaggtgatggaatcggacctgaagtaatggaatca
gcaatcaaagtccttgatactattgcaaaaaaatataatcataagtttaattatatagag
gctctaattggtggtgcagcttatgttaaatataaaagtcactgcccagaagaaacatta
gagatatgtaaaaattctgacgcaatactttttggctctgttggtggtcctgttgaagct
caaaatgaagaaaaatggcaaggctgtgaagctaatagtattctagctcttagaaaacat
tttggctttaatataaacattcgccctagcaaaatttttccagctcttagagaagcttgt
ccactaaaagatagtcgtattgcaaatggtgcagatattgaaatctttagagaattatct
agagatatttactttggtgagcatagaacttttacagatgaacatggtgtaaaatgtgca
actgatattgctgagtatgatgaacatacgattagaaatattgttgtacaagcatttgaa
agagctactcaacgctcaaatagacttacatctgtagataaggcaaatgtcctagataca
tcaaggctgtggagaaatattgtcaatgaagtagctaaagattatccaagtgtaaaagtt
aatcatatgtatgttgataattgcgctatgcaaatggtacttaatcctagtcaatttgat
gtaatggttactggcaatcttttcggtgatattatttctgatttagcttctgtattacca
ggttctattggcttagtaccatctataagcctaaataaagatggttttggattatatgag
ccttctggtggttctgcttatgatatcaaaggtcagggcaaagcaaacccaatcgcgcag
atattatctgcttcattaatgctttcttattcatttggcttagtaacagaggcagaagcc
attgcaagtgctatcaataagactcttgaagatggctttagaactcaagatatatacact
caaggaactaaactcgcttctactaaagaatttactaatgaaattataaaaaacctatag
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