Francisella tularensis subsp. novicida U112: FTN_0177
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Entry
FTN_0177 CDS
T00432
Symbol
purH
Name
(GenBank) AICAR transformylase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ftn
Francisella tularensis subsp. novicida U112
Pathway
ftn00230
Purine metabolism
ftn00670
One carbon pool by folate
ftn01100
Metabolic pathways
ftn01110
Biosynthesis of secondary metabolites
Module
ftn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ftn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FTN_0177 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
FTN_0177 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ftn04147
]
FTN_0177 (purH)
Enzymes [BR:
ftn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
FTN_0177 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
FTN_0177 (purH)
Exosome [BR:
ftn04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
FTN_0177 (purH)
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
ABK89087
UniProt:
A0Q4C2
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Position
complement(194356..195903)
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AA seq
515 aa
AA seq
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MSKIKRVLISVSDKTGIIEFAKELSKYNIEILSTGGTSKTLKDAGINVIDVSEHTQFPEI
MNGRVKTLHPLIHGGILADRDNPEHLDAMLKNHIGQIDMVVVNLYPFVNTVKSGADFDTC
IENIDIGGPSMVRSCAKNHKHTTIVTNPSQYDLVIKEMAENDGKTTLATRREFAKEAFAH
TAEYDSHIANWFSKELDEEYPEKLFSVGTLKQVLRYGENPHQKAAVYSTDADCVSITNAR
QLQGKELSYNNLNDADGAFEMVCEYSEPSCAIIKHANPCGIASGKNAFEAWTKALACDPI
SAFGGIVAFNCEVDKEFAESLGKMFLEVIIAPSYTQEALDILAAKKNLRVLETGKVFDTK
SSRMISKNIHGGILSQSYDNGGVDINDCKVVTDRAPTDKEWADLMFAWKAVKYVKSNAIV
YARDTQTVGIGAGQMSRVDSARIGAEKAQAHQGAKGSAVASDAFFPFADGLEECIKAGAT
AVIQPGGSKNDQEVIDAANKAGITMVFTNMRHFRH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgtcaaaaataaaaagggtactaatatctgtatctgataaaacaggtatcattgaattt
gccaaagaattaagtaagtataacatcgaaatactttcaacaggtggaacttcaaaaacc
cttaaagatgctggaataaacgtaatagatgtttcagagcatacacaatttccagaaatt
atgaatggtcgtgtaaaaacacttcatccactaattcatggtggtatcttagccgataga
gataatcctgagcatctcgatgcgatgctaaaaaatcatattggacaaatagatatggta
gtcgttaacttatacccttttgtcaatacagttaaatccggtgctgattttgatacctgt
atcgaaaacatagatatcggcggaccttctatggtgagatcatgtgcaaaaaatcataaa
cacacaactatagtgaccaaccctagccaatatgatctagttatcaaagagatggctgag
aatgatggtaaaactactctagcaacacgtcgtgaatttgctaaagaagcgtttgcacat
actgccgaatatgatagtcatattgcaaactggtttagtaaagagctagatgaagagtat
cctgagaaacttttttctgtaggaactctaaaacaggttctaagatatggcgaaaatcct
catcaaaaagcagctgtatactctacagatgctgactgtgtaagcattacaaatgcaaga
caattacaaggcaaagaattatcgtataataacctaaatgatgccgatggtgcttttgag
atggtttgtgagtattcagaaccctcttgtgcaattatcaaacatgctaatccttgtggt
atcgcttctggtaaaaatgcttttgaagcttggacaaaagctctagcttgtgatccaatt
tcagcttttggtggaattgttgcgtttaactgtgaagttgacaaagagtttgctgaatct
ctcggtaaaatgtttttagaagtaataattgcaccaagctatactcaagaagctctagat
attttagcagctaagaaaaacttacgcgtattagaaactggtaaagtttttgatacaaaa
tcatcacgtatgataagtaaaaatattcatggtggaatactatctcaatcttatgataac
ggtggtgttgacattaatgactgtaaagttgttacagatagagcgccaactgacaaagag
tgggctgatttaatgtttgcctggaaagctgttaaatacgtcaaatcaaatgcaattgtc
tatgctagagatacccaaacagtaggaattggtgctggacagatgagtcgagttgattct
gcacgtattggtgctgaaaaagcccaagctcatcaaggtgctaaaggttctgctgtcgca
tctgatgctttcttcccttttgctgacggtttagaagaatgtatcaaagctggagcaaca
gcggtaattcaaccaggcggttcaaaaaatgatcaagaagttattgatgctgctaacaaa
gctggtatcactatggtcttcacaaatatgagacattttagacactaa
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