Francisella tularensis subsp. novicida U112: FTN_0277
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Entry
FTN_0277 CDS
T00432
Symbol
gshA
Name
(GenBank) glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ftn
Francisella tularensis subsp. novicida U112
Pathway
ftn00270
Cysteine and methionine metabolism
ftn00480
Glutathione metabolism
ftn01100
Metabolic pathways
ftn01240
Biosynthesis of cofactors
Module
ftn_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ftn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FTN_0277 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
FTN_0277 (gshA)
Enzymes [BR:
ftn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
FTN_0277 (gshA)
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
ABK89185
UniProt:
A0Q4M0
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Position
285160..286665
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AA seq
501 aa
AA seq
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MYDFKKINNLRGIERETLRVTDCGNLATSNHPDGLGHKLTNNSITVDFSENLLELITKPH
DSIDKAIGELYQLSAFTLDNMHSDEIILNTSMPLSANDNDIQEADFGSSNSGRMKRVYRK
GLSARYGKIMQIISGIHYNFSFDKDLISNIATNKQVSISDIYFDVLNNYFEFMWLLPYLF
GASPICAKTSVKNKPNYLSVLDDEFYVGEYATSLRMSDLGYTSPAQKDLAISYDNVKAYV
KDLIQATDDTFADYKRIGLYNSQGQRIQLNDSILQIENEYYSAIRPKQIAKRGERPACAL
YNRGVEYVEVRVLDVDPFEPVGISKDTALFVEAMLMTCLEKDAKKYHKDIIKQAKQNLTA
VAIHGRNPQLKLKKLDDDSEILLKDYALELFDEIEAVAKKMPKEYLDAVEIQKRKVLDIS
QTPSAKIIELARQHGYKKFILDISRQVSQQFRSYELPAAIVAKLKDQAGQSVAAEKELIA
NDKISLDEYINRYYESSKGCC
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgtacgatttcaaaaaaataaataacctacgcgggatagaaagagaaactttaagagtt
actgattgtggtaatctagcaacttctaatcaccctgatggtttagggcataagttgact
aataatagtattaccgttgatttctctgaaaatttgcttgagctgataactaaaccgcat
gatagtatagataaagcaatcggtgagctatatcaactttcagcatttactttggataat
atgcacagtgatgaaattatccttaatactagtatgccactatctgctaacgataatgat
atacaggaagcagattttgggagctcaaattcggggcgaatgaagcgtgtttatcgtaaa
ggtctatctgcgcgatatggtaaaattatgcagataatttccgggatacattataatttt
tcttttgataaagacttaattagtaatattgctactaacaagcaggtatcaatatcagat
atttattttgatgtgcttaataactattttgagtttatgtggcttttaccgtatcttttc
ggcgctagtcctatatgtgctaagacttctgttaaaaataaacctaattatttatcagtt
ttagatgatgagttttatgttggtgaatacgctacaagcttgagaatgagtgaccttggc
tacacaagtcccgcacaaaaagatttagcaatatcatatgataatgttaaggcatatgtt
aaagatttaattcaagcaactgatgatacttttgctgattataagcgtataggtctttat
aattctcaaggtcaaagaatacagttaaatgatagtattttacagatagaaaatgaatat
tacagcgcaattagacctaagcaaattgctaaaagaggagagagacctgcttgtgcatta
tataaccgtggtgttgagtatgttgaggttagagttcttgatgtcgatccatttgagccg
gtgggtataagcaaagatacagcgctttttgttgaggcgatgttgatgacttgtctagag
aaagatgctaaaaaatatcataaagatattatcaaacaggcaaaacaaaatttaactgca
gttgcaatacacggacgtaatccacaacttaagcttaaaaagcttgatgatgatagtgaa
atacttttaaaagattatgctttagaattgtttgatgaaattgaggctgtagctaagaaa
atgcctaaagaatacttagatgctgttgaaattcaaaagcgcaaagtattagatatatcg
caaacaccttcagctaaaataatagaattagctagacaacatggttataaaaaatttatc
ttagatatatctcgccaagtatcacaacaattcagaagttatgagcttccagcagcaatt
gtagctaaattaaaagaccaagctggccaatctgttgctgcagaaaaagaattgattgct
aatgataaaatttccttagatgaatatatcaatagatattatgagtcttcaaagggttgt
tgttag
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