Francisella tularensis subsp. novicida U112: FTN_0420
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Entry
FTN_0420 CDS
T00432
Name
(GenBank) SAICAR synthetase/phosphoribosylamine-glycine ligase
KO
K13713
fusion protein PurCD [EC:
6.3.2.6
6.3.4.13
]
Organism
ftn
Francisella tularensis subsp. novicida U112
Pathway
ftn00230
Purine metabolism
ftn01100
Metabolic pathways
ftn01110
Biosynthesis of secondary metabolites
Module
ftn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ftn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FTN_0420
Enzymes [BR:
ftn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
FTN_0420
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
FTN_0420
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Gene cluster
GFIT
Motif
Pfam:
SAICAR_synt
GARS_A
GARS_N
GARS_C
Motif
Other DBs
NCBI-ProteinID:
ABK89323
UniProt:
A0Q508
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Position
418362..420674
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AA seq
770 aa
AA seq
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MLDKQIIINNIKNVLKSTNLDIKNKYIGKVRDMYFTDDKSILISTDRQSAFDRSLGFIPF
KGQILAQSSVWWFKETAHIVKNHFIDSPDPNVVIARKAKVLPIEFVVRGYITGSTSTSLW
THYKNGSRDYCGNILPEGLKKNQKLPQNILTPTTKEQDHDRPISAEDIVKEGWLTQQQWD
FASQKALELFEFGQKKALEHGLILADTKYEFGIDEQTGEIILIDEIHTPDSSRFWLKDSY
ATRFENGEEPENIDKEFFRLWFAKNCDPYNDEVLPQAPQELVVELSQKYITLFEMITGQK
FEVPRDLENINQRIVKNVTDYLNMEKPVNILLVGSGSREHAIAEAVKRSSIANKLFCIST
AINPGIDKIIQGYQIADICNCDEVLEYAKSQSIDIAIIGPEAPLEAGLADALKTAAIGVV
GPTKKLAQLETSKGFTRDLIRDYDIGANPFFRKFNSMDGVEETLKKYQNQFVIKADGLCG
GKGVLVWGDHLHSLDEAIRHCQSLVDAGKEFVIEEKLVGQEFSLISFTDGKNFIHMPAVQ
DHKRAHEGDKGPNTGGMGTYSDANHSLPFLSAADIERAKQINEKVVKALADKFGEPYQGI
LYGGFMATKDDTKVIEYNARFGDPEAMNLLTLLETDFVEIAQAITQGKLDTVKAKFKNQA
SVCKYLVPLGYPNQSVKNFEIDISQCPDNVELFLGAVDYKDGKLIGTGSRAIAVLGLGDT
IAEAEQKAENAVKNIYGKLFHRPDIGTKELINKRIKHMNLLRGDKYQELK
NT seq
2313 nt
NT seq
+upstream
nt +downstream
nt
atgcttgataaacaaatcatcatcaataatataaaaaatgttctaaaatcaacaaatctt
gatatcaagaataaatatataggtaaagtaagagatatgtactttactgatgataagagt
attttgatatctacagatagacaatctgcttttgatagatctttgggctttataccattt
aaggggcaaatccttgcacaatcatcagtatggtggttcaaagaaacagcacatattgtc
aaaaaccattttatagactctccagatccaaatgttgtcatcgcgagaaaggcaaaagta
ttgccaattgagtttgtcgttagaggttatataactggttcaacttctacatcattgtgg
acacattacaaaaatggaagtcgtgactattgtggcaatatcctgccagaaggtttaaaa
aagaatcaaaaattaccacaaaatatccttacaccaactaccaaagagcaggatcatgat
cgcccaatttcagctgaggacattgtcaaggaaggttggctaactcagcagcagtgggac
tttgcttcacaaaaagctctagaactttttgagtttggacaaaaaaaagccttagaacat
ggcttaatcttggcggatactaaatatgagtttggtattgatgagcaaactggagagatt
attttgatcgatgagatccatactccagatagctcaagattttggctaaaagatagctat
gctacaagatttgaaaatggtgaagagccagagaatattgataaagaattttttagatta
tggtttgcaaaaaattgtgacccatataatgatgaagttttaccacaagcaccacaagag
ttagttgtcgaattatctcaaaaatatataaccctttttgaaatgataacggggcaaaag
tttgaagtaccaagagatttagaaaatataaatcaacgtattgttaaaaatgttacagat
tacttaaatatggagaagccagtgaatattcttctagtaggatcaggaagtagagagcat
gcaatagcagaagcagtcaaaagaagctctattgcaaataagcttttttgtataagcaca
gcgattaaccctgggatagataagataatacaagggtatcaaatcgctgatatttgtaat
tgtgatgaagtactagagtatgcaaaatcacaaagtattgatattgcgattatcggtcct
gaagcaccacttgaggctggtttagctgatgcacttaagacagcagcaattggtgtagtt
ggtccaaccaaaaagttagcacagcttgaaacatcaaaaggttttactagagatctgatc
cgtgattatgatataggcgctaatcctttctttagaaagtttaactcgatggatggagtc
gaagagactctcaaaaaatatcaaaatcaatttgtcataaaagctgatggtttatgtggt
ggtaaaggagtgcttgtttggggcgatcatttgcacagccttgatgaggcgattagacac
tgtcagtcattggtagatgctggcaaagagtttgttatcgaggagaagcttgttggccag
gaattctcgctaatatcatttactgatggcaaaaattttatccatatgccagcagtccaa
gatcataagcgtgcccatgaaggtgacaaaggtcctaataccggtggtatgggtacttat
tctgatgctaatcatagtttaccgtttttatcagctgctgatatcgaaagagcaaaacaa
ataaatgagaaagttgtcaaagctttagctgataaatttggtgaaccatatcaaggtatc
ctttatggtggctttatggcgacaaaagatgatactaaagtgatcgagtataatgcacgt
tttggtgatccagaagcgatgaatctacttacactgttagagacagattttgttgagatt
gctcaagctattacacagggtaaacttgatacagtcaaagctaagtttaaaaatcaagca
agcgtatgtaaatatctagtaccgcttggctatccaaaccaatcagttaaaaactttgag
atagatatttcacaatgccctgataatgtcgagcttttcttaggtgctgttgattataaa
gatggtaagctaattggtacaggctctagagctatagctgtacttggtttgggtgataca
atagctgaagcagagcaaaaagccgaaaatgctgtcaaaaatatttatggtaaactattt
catcgtccagatattggtactaaagagcttatcaataagcgtatcaaacacatgaatttg
ttgcgtggtgataaatatcaggagcttaaataa
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