Francisella tularensis subsp. tularensis NE061598: NE061598_02345
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Entry
NE061598_02345 CDS
T01938
Name
(GenBank) UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ftr
Francisella tularensis subsp. tularensis NE061598
Pathway
ftr00300
Lysine biosynthesis
ftr00550
Peptidoglycan biosynthesis
ftr01100
Metabolic pathways
ftr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ftr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NE061598_02345
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NE061598_02345
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NE061598_02345
Enzymes [BR:
ftr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NE061598_02345
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ACBP4_C
DUF7197
Motif
Other DBs
NCBI-ProteinID:
ADA78117
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Position
436433..437791
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AA seq
452 aa
AA seq
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MIKSLKQLAIQAGLEYLGEDVSIQTVAINSNEVRQDCLFVAIVANRDGHEFIPSAIANGA
KAILVSKKQGLDIPQVVCGNTIKGLRALAKEYRKSLTMPIISLTGSCGKTSVKEMIVTLL
GERKVHFTQGNLNNYLGVPMTILETPHDVDFAVIEAGTNVGGEIKAAADIIQPNIAMITN
VGACHLENLKTLDGVMIEKGELLKALPRDGFCIVNLDDERIPNYAKLLECKKISCSMTNP
KADILVLDYRATSNSYAFKIRIFSQEYDYQLPNIGKHNLFNSVLAIASVVAVGLEPKDFL
QNTQNIKNYKGRFSTEKLSDKLTLIDDTYNASAGAVQAAIEDLAEFDGKKILAISSMREL
GDEAENYHRKMGQWLKKANLDKIFLFGEKNLIDYVLAEYSNQNAKYYESKDELNNDLAKI
LDEYKSQSTKLTVKGARSFKMEEVVKFVKENL
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgataaaatcactaaaacaattagcaatccaagcaggcttagaatatttgggtgaagat
gtatcaatacaaacagtagctataaattcaaatgaagtaagacaagattgcttatttgtt
gcaattgtagctaatcgtgatggacacgagtttattccaagtgctattgctaatggcgct
aaagctattttagtttcaaaaaaacaaggtttagatattccacaagtagtttgtggcaat
actatcaaaggcttacgggctttagctaaagaatatcgcaaatcactaactatgccaata
atatctttaactgggagttgcggtaaaacatctgttaaagaaatgattgtaactcttctt
ggtgagagaaaagttcattttactcaaggtaacctaaataattatcttggtgtaccaatg
acaatattagaaacaccgcatgatgtcgattttgcagtgattgaggcaggtacaaatgtt
ggtggtgagataaaagctgcagctgatattatccaaccaaatatagcgatgattacaaat
gttggcgcttgccaccttgagaacctaaaaacgctggatggtgtaatgatagaaaaaggg
gagcttctcaaagctttgccaagagatggtttttgtatcgtaaatctagatgatgaaaga
attccaaattatgctaagctgctagagtgtaaaaagattagctgctcaatgactaatcca
aaagctgatattttagtattagattatagggcaacatcaaatagttatgcttttaagatt
agaatttttagccaagagtatgattatcaactaccaaacattggcaagcataatttgttt
aatagtgtcttggctattgctagtgtagttgctgtggggcttgagcctaaggatttctta
caaaatacacaaaatatcaaaaactataaaggtagattttcaactgaaaaactcagtgat
aaactaactcttatagatgatacatataatgcaagtgctggcgctgtgcaagctgcaatt
gaagatttggcagaatttgatggtaaaaaaatattggctattagttcaatgcgtgagcta
ggagatgaagctgaaaattatcatcgaaaaatggggcaatggcttaaaaaggcaaattta
gataagatatttttatttggtgagaaaaatttaatagattatgttttggcagaatattca
aaccagaatgctaaatattatgaatctaaagacgagctaaataatgatttagctaaaata
ttggatgaatataagtcacaaagtactaagctaacagtcaaaggggctagaagttttaag
atggaagaagttgtcaaatttgttaaggaaaacttataa
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