Francisella tularensis subsp. tularensis WY96-3418: FTW_0078
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Entry
FTW_0078 CDS
T00495
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ftw
Francisella tularensis subsp. tularensis WY96-3418
Pathway
ftw00230
Purine metabolism
ftw01100
Metabolic pathways
ftw01110
Biosynthesis of secondary metabolites
Module
ftw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ftw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FTW_0078 (purL)
Enzymes [BR:
ftw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
FTW_0078 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF5537
Motif
Other DBs
NCBI-ProteinID:
ABO46075
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Position
88515..92387
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AA seq
1290 aa
AA seq
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MITIFEGLSALSPFKREKILAAAKKISNKVESVSAQYIHVTELESELNSEQERIVKSLLN
YNREYGIAQPMGHTFIIAPRVGTISPWSSKATDIIKNTGIKAVKRIERAILFGVEGQVSA
SELKQIQDIVHDRMVEEVFSCKDDLYRLFSVTAPKELEFVNVLEKGAQAIKEADRKLGLA
LSEQEIEYLADEYTKLGRNPTDTELYMFAQANSEHCRHKIFNAKWTIDGQEQDKSLFKMI
RNTTEKSPQGVLSAYKDNAAVIEGATAQRFYPNTQTGVYSFNQEEVDILMKVETHNHPTA
IAPFSGSATGVGGEIRDEGATGLGAKPKAGLTGFTVSNLNIPGFEQAWETSKYGKPNHIV
TPLQIMLEAPIGGAHYSNEFGRPNLNGYFRTYEQEVNTSAGKEMFGYHKPIMIAGGMGNI
KRMHVEKGDIKVGAKLICLGGPAMRIGLGGGAASSVVSSDTNSELDFASVQRDNAEMERR
CQEVIDRCWQMGENNPITFIHDVGAGGISNAFPELVKDGGVGGYFELRKVNVGEEGLSPL
EIWSNESQERYVLSVDPESLELFEQLCNRERCPFAVVGEAISEKHITLNDEYFDNKPVDL
PMGLLFGNTPQMHIDVKTVKVEQQAFDTSAIKLDEAIERVLKVPAVASKSFLITIGDRSI
TGMVARDQMVGPWQVPVADCAVTTATVDSQAGEAMAMGERTPVAAINAAASGRLAIAETV
TNLLAADIEKLSDIRLSANWMVAANQGDENQKLYETVRAVGMEFAPALGIAIPVGKDSMS
MKTKWSDNGQAKSVTSPLSLVISGFSPVTNARKTLTPVLVDDNDTTLLHIDLSNGAGRLG
ASCLAQAYNQVGNVAPDIEASKVKVLFENITKLKAENKILAYHDVSDGGVFATLAEMSFA
GRKGLDVKLQTQDVLAKLFAEEVGVVIQVRNSDVSLVEEMFKDTQIHLCAIAKLNSSDEL
NIFVNGEKIYSNTRVNLQRWWAETSYQIQSIRDNSECAKQEFDSILNTNDKGIHVEATFD
LEEDITAKFVNVEKPKVTILREQGVNGQVEMAAAFTTAGFEAHDVHMSDLHAGRVTLADF
KVLVACGGFSYGDVLGAGGGWAKNILFTEKLRDEFSRFFGRDDTLALGVCNGCQMLAQLK
SLIKGAENWPIFIKNKSEQFEARVSMVEIQESDSIWFADMACTKAPIAVAHGEGRPLFEN
DNQQQAMLASAQVALKYIDGQGQATEMYPYNPNGAVNGLTAVTALDGRVLAMMPHPERVY
RAITNSHIPAEYDEYSVWMRMFRNARKWVG
NT seq
3873 nt
NT seq
+upstream
nt +downstream
nt
atgattacgatttttgaaggtttaagtgcactgtctccttttaagcgagaaaaaatttta
gcagctgctaaaaaaatatccaataaagttgaatcagtatctgcacagtatatccatgtt
acagagcttgaatcagagttaaatagtgagcaagaaagaatagttaaatctctacttaac
tacaatagagagtatggcatagctcaacctatgggtcatacttttatcatagctccaaga
gttggcactatatcgccttggtcttctaaagctaccgatattatcaaaaatactggtatc
aaagctgttaaaaggatagaaagagctattttattcggtgttgagggacaagtttctgct
agtgagctaaaacaaatccaagatatcgttcatgaccgtatggttgaggaagtgtttagt
tgcaaagatgatttatatagactctttagtgtaacagcaccaaaagaacttgaatttgtt
aatgttttagaaaaaggtgctcaagctatcaaagaagctgatagaaaacttggcttagct
ctaagtgagcaagagattgaatatctagcagatgaatatacaaagcttggtagaaatcct
acagatacagagttatatatgtttgcccaagcaaattcggagcattgtagacataagatt
tttaatgctaaatggactatagatggtcaggagcaagataaatcattgtttaagatgatt
agaaatactactgagaaatctccacaaggtgtgctatcagcatataaggataatgctgct
gtgatagagggtgcaacggctcaaagattctatccaaatacgcaaactggtgtctatagt
ttcaatcaagaagaagttgatatcttgatgaaagttgagactcataatcacccaactgct
atagcaccatttagtggctcagctactggtgttggtggtgagattcgtgatgaaggtgca
acaggtcttggagcaaaaccaaaagctggcttgactggttttacagtttcaaatctaaat
attccaggttttgaacaggcttgggagactagtaaatatggtaagcctaaccatattgta
acacctttacaaataatgctagaggcgcctattggtggtgctcattactcaaatgaattt
ggtcgtccaaatttaaatggttatttccgtacctatgagcaagaggtcaatacatctgct
ggcaaagagatgtttggataccataagccaattatgattgctggtggtatgggtaatatc
aaaagaatgcatgttgagaaaggcgatatcaaagttggtgctaagctaatctgtcttggt
gggcctgcgatgcgtattggtcttggtggtggtgctgcgtcatctgttgtatcttctgat
actaactcagagctggattttgcatcagttcagcgtgataatgccgaaatggagcgccgt
tgccaagaggtaatcgacagatgttggcaaatgggcgagaataacccaatcacatttatc
catgatgttggtgctggcggtatttcaaatgctttcccagagcttgtcaaagatggtggc
gtaggcggttattttgagcttagaaaagtaaatgtcggtgaagaggggctttctccactg
gaaatatggtcaaatgagtcacaagaaagatatgtattatcagttgaccctgagtcacta
gagctttttgagcagttatgtaatagagaaagatgtccatttgcagtagttggtgaggcg
atttctgaaaagcatatcactctaaatgatgagtattttgataataagccggttgattta
ccaatgggattattatttggtaatacaccacaaatgcatattgatgtaaaaactgtcaaa
gttgagcaacaagcttttgatacaagtgctattaagcttgatgaagcgattgagagagtg
ctaaaagtaccagctgtagcttctaaatctttcctaatcacgattggtgatagaagtatt
acaggtatggttgcacgagatcaaatggttggtccatggcaagtgcctgtagctgattgt
gctgtgacaactgctactgtagatagtcaagctggtgaggctatggcaatgggcgagaga
actcctgttgctgctattaatgctgcggcttctggtagattagcgattgctgagactgta
acaaacttattagctgcggatattgaaaagttgagtgacattcgcctctctgctaactgg
atggttgctgcaaatcaaggtgacgaaaaccaaaaattatatgaaactgtaagagctgtt
ggtatggaatttgcaccagcgttgggtattgcaataccagttggtaaagattcaatgtca
atgaaaactaagtggtcagataacggtcaagctaaatcagtgacatcgccattatcttta
gtgatctcaggtttctcgcctgtgacaaatgcgcgtaagactcttacaccagttttagtt
gatgataatgatacaactttattacacattgatctatcaaatggtgccggtagacttggg
gcttcatgtttagctcaagcttataatcaagttggtaatgttgcgccagatattgaagca
agtaaggtaaaagtgctatttgaaaatatcactaaactaaaagctgaaaataaaatttta
gcatatcatgatgtatctgatggtggtgtgtttgcaactttagcagaaatgtcatttgca
gggcgtaaaggtttagatgttaaactacaaactcaagatgtgttagcgaaactctttgcc
gaggaagttggagttgttatccaagttcgaaatagcgatgtatcactagttgaagagatg
tttaaagatactcaaattcacctatgtgcaatagctaagctaaactctagtgatgagcta
aatatctttgtaaatggtgaaaaaatatactcaaacacacgtgtaaatttacaaagatgg
tgggctgagacttcttatcaaatccaatcaattcgtgataatagcgaatgcgctaaacaa
gagttcgatagtatcttaaatactaatgataaaggtatccatgttgaggctacatttgat
cttgaagaggatatcacagctaagtttgtcaatgttgaaaagccaaaagttacaatctta
agagagcaaggtgtcaatggtcaagttgagatggcagcagcatttactacagctggcttt
gaggctcatgatgtccatatgtcagatttacatgctgggcgtgtaactttggcagatttc
aaagtattggtagcttgtggtggtttctcatatggtgatgtcttgggcgctggcggtggc
tgggcgaagaatatcctctttactgagaagctaagagatgagtttagtagattctttggg
cgtgatgatactttagcattaggtgtatgtaatggttgccaaatgcttgcacagcttaaa
tcactaatcaaaggcgctgaaaactggccgatatttatcaagaataaatcagagcagttt
gaggctagagtgtctatggttgagattcaagagtctgactctatttggttcgctgatatg
gcatgcacaaaagcaccaattgctgtagctcatggtgagggtcgcccattatttgaaaat
gacaaccagcaacaagctatgctagcaagtgctcaagtagctcttaaatatattgatggg
caaggtcaagcaactgagatgtatccatacaatccaaatggtgcagtaaatggtctaaca
gctgtgacagctttagatggtcgtgtccttgcgatgatgccacatccagagcgtgtgtat
agagctattacaaactcgcatatcccagcggaatatgatgagtattctgtatggatgaga
atgtttagaaatgctaggaagtgggttggatga
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