Francisella tularensis subsp. novicida U112: AW25_289
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Entry
AW25_289 CDS
T03874
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ftx
Francisella tularensis subsp. novicida U112
Pathway
ftx00230
Purine metabolism
ftx01100
Metabolic pathways
ftx01110
Biosynthesis of secondary metabolites
Module
ftx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ftx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
AW25_289 (purL)
Enzymes [BR:
ftx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
AW25_289 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF5537
Motif
Other DBs
NCBI-ProteinID:
AJI60538
UniProt:
A0Q8J1
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All DBs
Position
309648..313535
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AA seq
1295 aa
AA seq
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MITIFEGLSALSPFKREKILAAAKKISNKVESVSAQYIHVTELELELNSEQERIVKSLLN
YNREYGVAQPIGHTFIIAPRVGTISPWSSKATDIIKNTGIKAVKRIERAILFGVEGQVSA
SELKQIQDIVHDRMVEEVFSCKDDLHRLFSVTAPKELEFVNVLEKGTQAIKEADRKLGLA
LSEQEIEYLADEYTKLGRNPTDTELYMFAQANSEHCRHKIFNAKWTIDGQEQDKSLFKMI
RNTTEKSPQGVLSAYKDNAAVIEGATAQRFYPNTQTGVYSFNQEEVDILMKVETHNHPTA
IAPFSGSATGVGGEIRDEGATGLGAKPKAGLTGFTVSNLNIPGFEQAWETSKYGKPNHIV
TPLQIMLEAPIGGAHYSNEFGRPNLNGYFRTYEQEVNTSAGKEMFGYHKPIMIAGGMGNI
KRMHVEKGDIKVGAKLICLGGPAMRIGLGGGAASSVVSSDTNSELDFASVQRDNAEMERR
CQEVIDRCWQMGENNPITFIHDVGAGGISNAFPELVKDGGVGGYFELRKVNVGEEGLSPL
EIWSNESQERYVLSVDPESLELFEQLCNRERCPFAVVGEAISEKHITLNDEYFDNKPVDL
PMGLLFGNTPQMHIDVKTVKVEQQAFDTSAIKLDEAIERVLKVPAVASKSFLITIGDRSI
TGMVARDQMVGPWQVPVADCAVTTATVDSQAGEAMAMGERTPVAAINAAASGRLAIAETV
TNLLAADIEKLSDIRLSANWMVAANQGDENQKLYETVKAVGMEFAPALGIAIPVGKDSMS
MKTQWLDKSGSDNGQAKSVTSPLSLVISGFSPVTNARKTLTPVLVDDNDTTLLHIDLSNG
AGRLGASCLAQAYNQVGNVAPDVEASKLKVLFENITKLKAENKILAYHDVSDGGVFATLA
EMSFAGRKGLDVKLQTQDVLAKLFAEEVGVVIQVRNDDVALVEEMFKDTQIHLCAIAKLN
SSDELNIFANGEKVYSNTRVNLQRWWAETSYQIQSIRDNSECAKQEFDSILNTNDKGIHV
EATFDLEEDITAKFVNVEKPKVAILREQGVNGQVEMAAAFTTAGFEAHDVHMSDLHAGRV
TLADFKVLVACGGFSYGDVLGAGGGWAKNILFTEKLRDEFSKFFGRDDTLALGVCNGCQM
LAQLKSLIKGAENWPIFIKNKSEQFEARVSMVEIQESDSIWFADMAGTKAPIAVAHGEGR
PLFENDSQQQAMLASSQVALKYIDGQGQATEMYPYNPNGAVNGLTAVTALDGRVLAMMPH
PERVYRAITNSHIPAEYDEYSVWMRMFRNARKWVG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgattacgatttttgaaggtttaagtgcactgtctccttttaagcgagagaaaatttta
gcagctgctaaaaaaatatctaataaagttgaatcagtatctgcacagtatatccatgtt
acagagcttgaattagagttaaatagtgagcaagaaagaatagttaaatctctacttaac
tacaatagagagtatggcgtagctcaacctataggtcatacttttatcatagctccaaga
gttggcactatatcgccttggtcttctaaagctactgatattatcaaaaatactggtatc
aaagctgttaaaaggatagaaagagctattttattcggtgttgagggacaagtttctgct
agtgagctaaaacaaatccaagatatcgttcatgatcgtatggttgaggaagtgtttagt
tgcaaagatgatttacatagactctttagtgtaacagcaccaaaagaacttgaatttgtt
aatgttttagaaaaaggtactcaagctatcaaagaagctgatagaaaacttggcttagca
ctaagtgagcaagagattgaatatctagcagatgaatatacaaaacttggtagaaatcct
acagatacagagttatatatgtttgcccaagcaaattcggagcattgtagacataagatt
tttaatgctaaatggactatagatggtcaagagcaagataaatcattgtttaagatgatt
agaaatactactgagaaatctccacaaggtgtgctatcagcatataaggataatgctgct
gtgatagagggtgcaacggctcaaagattctatccaaatacgcaaactggtgtctatagt
ttcaatcaagaagaagttgatattttgatgaaagttgagactcataatcacccaactgct
atagcaccatttagtggctcagctactggtgttggtggtgagattcgtgatgaaggtgca
acaggtcttggagcaaaaccaaaagctggcttgactggttttacagtttcaaatctaaat
attccaggttttgaacaggcttgggagactagtaaatatggtaagcctaaccatattgta
acacctttacaaataatgctagaggcgcctattggtggagctcattactcaaatgaattt
ggtcgtccaaatttaaatggttatttccgtacctatgagcaagaggtcaatacttctgct
ggtaaagagatgtttggataccataagccaatcatgattgctggtggtatgggtaatatc
aaaagaatgcatgttgagaaaggcgatatcaaagttggtgctaagctaatctgtcttggt
ggacctgcgatgcgtattggtcttggtggtggtgctgcgtcatctgttgtatcttctgat
actaactcagagctagattttgcatcagttcagcgtgataatgccgaaatggagcgccgt
tgccaagaggtaatcgacagatgttggcaaatgggcgagaataacccaatcacatttatc
catgatgttggtgctggcggtatttcaaatgctttcccagagcttgtcaaagatggtggc
gtaggcggttattttgagcttagaaaagtaaatgtcggtgaagaggggctttctccactg
gaaatatggtcaaatgagtcacaagaaagatatgtattatcagttgaccctgagtcacta
gagctttttgaacaactttgtaatagagaaagatgtccatttgcagtagttggtgaggcg
atttctgaaaagcatatcactctaaatgatgagtattttgataataagcctgttgattta
ccaatgggattattatttggtaatacaccacaaatgcatattgatgtaaaaactgtcaaa
gttgagcaacaagcttttgatacaagtgctattaagcttgatgaagcgattgagagagtg
ctaaaagtaccagctgtagcttctaaatctttcctaatcacaattggagatagaagtatt
acaggtatggttgcacgagatcaaatggttggtccatggcaagtgcctgtagctgattgt
gctgtgacaactgctactgtagatagtcaagctggtgaggctatggcaatgggtgaaaga
actcctgttgcggctattaatgctgcggcttctggtagattagcgattgctgagactgta
acaaacttattagctgcggatattgaaaagttgagtgacattcgcctctctgctaactgg
atggttgctgcaaatcaaggtgacgaaaaccaaaaattatatgaaactgtaaaagctgtt
ggtatggaatttgcaccagcgttgggtattgcaataccagttggtaaagattcaatgtca
atgaaaacccagtggttagataaatcggggtcagataacggtcaagctaaatcagtgact
tcaccgttatcattagtgatttcaggcttctcacctgtgactaatgcacgtaagactctt
acaccagttttagttgatgataatgatacaactcttttacatattgatctatcaaatggt
gctggaagacttggagcttcatgtttagctcaagcttataatcaagttggtaatgttgca
ccagatgttgaagcaagtaagttgaaagtgctatttgaaaatatcactaagctcaaagct
gaaaataaaatcttagcatatcatgatgtatctgatggcggtgtgtttgcaactttagca
gagatgtcattcgctgggcgtaaaggtttagatgttaaactacaaactcaagatgtgtta
gcgaaactctttgccgaggaagttggggttgttatccaagttagaaatgatgatgtagca
ctagttgaagagatgtttaaagatactcaaattcacctgtgtgcaatagctaaactaaac
tctagtgatgagctaaatatctttgcaaatggtgagaaagtatactcaaacacacgtgta
aacttacaaagatggtgggctgagacttcttatcaaatccaatcaattcgtgataatagc
gaatgtgctaaacaagagttcgatagtatcttaaatactaatgataaaggtatccatgtt
gaggcaacatttgatcttgaagaagatattacagctaagtttgtcaatgttgagaagcca
aaagtcgcaatcctaagagagcaaggtgtcaacggtcaagttgagatggcagcagcattt
actacggctggttttgaggctcatgatgtgcatatgtcagatttgcatgctgggcgtgta
actttggcagatttcaaagtattggtggcttgtggtgggttctcatatggtgatgttttg
ggtgctggcggtggctgggcgaagaatatcctctttactgagaaactaagagatgagttt
agcaaattctttggtcgtgatgatactctggcattaggtgtgtgtaatggttgccaaatg
cttgcacagcttaaatcactaatcaaaggtgctgaaaactggccgatatttatcaagaat
aaatcagaacagtttgaggcaagagtttctatggttgagattcaagagtctgactctatt
tggtttgctgatatggcgggtacaaaagcaccaattgccgtagctcatggtgagggtcgt
ccattatttgaaaatgacagccagcaacaagctatgctagcaagctcacaagtagcactt
aaatatatcgatgggcaaggtcaagcaactgagatgtatccatacaatccaaatggtgca
gtaaatggtctaacagctgtgacagctctagatggtcgtgtccttgcaatgatgccacat
ccagagcgtgtctatagagcgattacaaattcgcatatcccagcagagtatgatgagtat
tctgtatggatgagaatgtttagaaatgctaggaagtgggttggataa
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