Gossypium arboreum (tree cotton): 108483782 Help Entry 108483782         CDS       T05776                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism gab  Gossypium arboreum (tree cotton) Brite KEGG Orthology (KO) [BR:gab00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:gab04121]     108483782 Enzymes [BR:gab01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      108483782 Ubiquitin system [BR:gab04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     108483782 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 UBR4 ZZ zf-UBR Motif Other DBs NCBI-GeneID:  108483782 NCBI-ProteinID:  XP_017642850 LinkDB All DBs Position 7:17703941..17724377 Genome browser AA seq 5090 aa AA seqDB search MADHLTRLCQFLAEEKLSSSSSSLDLLLKLRSDESIKLGLQQLYLILQTGLHPIEPGSHP LFKSWSDNQILSLASLGSCITSVFRSLSVEQLEPIIVAVARKLVEFTVSFLGKSDFSGDD LSVQSNMIQLLEIILGGGTDKIVDSLQPASVNSLVDLLPIVSCNLGSIELDNDIKCGLQG MKCSRAEKQVDRLLSALASECVQPERHTSGFEAPSFHQDLNSLVFLSQHWAVAHAECIRS LILLCKELVELPDIFDERIAGANFRKRLSFSLRILKSLGCLLKDVPYVEYDSSVLEAIAL CADVLPNLFRPSFEFVNNIAVTDGNFESLVLSLLEEFIHLVRLMFCNSVVFQNVQACIVA SILEHLGPSIWRYNKASSNIKPPLAYFPRSVIYTLKLIQDLRIELKEVVDLKELDTELGG SVDLSKDSPLCHIHAQKVPLLQRFTIDELSKMIFPSSSNWMDNLMHLTSFLHSEGVKLRP KMERSTSCGRSNCSSELETAVCHDDEALFGNLFSEGSRTLGSADVCDQTSAVSSSSSNCN MPMQAAMELLSFLKGCIFSHDWLPSVYEDGCRMLSVDHIDILLYILSCQGGPFEDNFAAS HEDRKSGHIQELSFQLLHNLLTHHALSDSLEDYLVERILNVEDAAFVYNDQTLALLAHAL FSKVDFAGSQLRTKIYRGFVSFIVEKAKSICSDCPTLKELLVTLPSVFHIEILLMAFHLS PDEEKVTLANFVFSALQTVHVPSTGSYGTQLSCWALVVSRLILLLRHMILHPRTCPPSML LAFRSKLRDIQSFASHVPTNSIDSFSSLASIAVKTLTGALVDEEPSCSSLIHQLIDVTYI QSPIYMDDVAIGSLHLSWDDMCSRFSYILGFWNGKKAAAIEDLIIERYIFLLCWDIPTMK SPLGHQLSLWSNLQSLEISSREQFFCFSHLLLGQCDVIGKGADFQKLVVGLLGHLQAAHL QDNFENLGWDFLRNGMWLSLVLSFFNVGIGRYCVKNNIPGGGPIWTENRPSDNDYINSAE GFISGLIADNRTSELLRMFASFLKGYLQFYEKAFLATLGDSKHDDYMFSPVLLLKLSMFD KSLLDELLKKCAVDSFQLESVLDILLKVDGAVEKRASGILAKVFWECMLHGFPSHLQASS GILLSCILNIRRIIFTLDGLLKLSNMKGNIFLEIDVLHQILDSLTSVKLDRIFERLRGKC EDVWLNLNAGLELSDYTELFLLKRMEGFLRYIHSREMGDTSILEWVITKTIDTMDALRKD PKKSTLFKFYLGAGDMSESLKELHGSERGDILVLIDSVCNCHTELVNIKVLSFFIDLLSG ELCPNLNLKIQNKYLSMDLLLLSKWLEKRLLGCTAEAMDGVKSVKANSVSLRESTMSFIL CLVSSPSELQSELYNHLFEAVLISLETAFLQFDIHTAKSYFHFVVQLARGESSMKLLLKR TVMLTQKLAGEERLLPGLKFILGFLGCFLSDCGSSSNTTEKCSGKSLSISSVAVGPVASR PVGSRKNSDVLVLPANRDGATATLECDATSVDEDEDDGTSDGEEASIDKDEEEDTNSERA LASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYSRSSRFFCDC GAGGVRGSSCQCLKPRKFTGSDSALNCGTNSFQSFLPLTEDTDQLPESDSDMDEDVGADM ENSLRLSIPKDLQDGISMLLEELDVERQVLELCSTLLPSITGRRESNLSKDKKIILGKDK VLSYGIDLLQLKKAYKSGSLDLKIKTDYSNGKELKLHLASGSLVKSLLSVSIRGRLAVGE GDKVTIFDVGQLIGQATIAPVTADKANLKALSKNLVRFEIVHLSFNLVVENYLAVAGYED CQVLTLNPRGEVTDRLALELALQGAYIRRIEWVPGSQVQLMVVTNRFVKIYDLSQDNISP MHYFTLADDTIVDATLIVASQGRMFLVVLSERGSLFRLGLSLEGHVGATPLKEIIRIQDR EIHAKGSSLYFSSTYKLLFLSYQDGTTLIGRLSPDASSLTEISCVYEEQDGKLRPAGLHR WKELLVGSGLFCGFSSVKSNSAIAVSFGADELFAQNLRHAVSSSLPLVGITAYKPLSKDK VHCLVLHDDGSLQIYSHVPMGVDAAASATAEKVKKLGSNILNNKAYAGTKPEFPLDFFEK TVCITADVKLSGDAIRNGDSEGAKQSLASEDGFLESPSPAGFKISVSNSNPDIVMVGFRV YVGNQSANHIPSEITIFQRVIKLDEGMRSWYDIPFTVAESLLADEEFIISVGPTFSGSAL PRIDSLEVYGRAKDEFGWKEKMDAVLDIEARVLGANSVLAGSGKKSRSMQSAPIQEQVVA DGLKLLSRIYCLCRSQEEELKVDLSKLKSKQLLEAIFESDREPLMQAAACRVLQAVFPKK EIYYQIKDTMRLLGVVKSTSILSSRLGIGGATGQWLIEEFTAQMRAVSKIALHRRSNLAN FLEMNGSEVVDGLMQVLWGILDLELPDTQTMNNIVISAVELIYSYAECLALHGKDTGRRS VAPAVILFKKLLFFPNEAVQTSSSLAISSRLLQVPFPKQTMLGTDDVVESAVTSSMPADT SDGNTQVMIEEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFDLCEACYEVLDADRLPA PHSRDHPMTAIPIEVESLGGDGSEIRFSTDDLSDSNLVTNVTDVGMQTSAPSIHVLEPSE SMEFSSSMADPVSISASKRAVNSLLLSELLEQLKGWMETTSGIRAIPVMQLFYRLSSTVG GPFIDSSKSETLDLEKLIKWFLNEINLNKPFVARTRSSFGEVAILVFMFFTLMLRNWHQP GSDGTASKGTGNTDTPDKSGSQVSGSVASPSSLVDHDKNDFASQLLRACNSLRNQAFVNY IMDILQQLVHVFKSPAAGLENAHGSNVASGCGALLTIRRDLPAGNFSPFFSDSYAKAHRA DTFMDYHRLLLENAFRLVYTLVRPEKHDKNGEKEKVPKTSSGKDLKLDGYQEVLCSYINN PHTTFVRRYARRLFLHMCGSKTHYYSVRDSWQFSTEVKKLYKHVNKSGGFQNPVPYERSV KIVKCLSTIAEVAAARPRNWQKYCLRHSDVLPSLMNGIFYFGEESVIQTLKLLNLAFYLG KDMSHSSQKAESGDSGTTSNKSGTQSLDSKKKKKGDDGVETGLEKSFVDMEMVVEIFTDK GGDVLRQFIDCFLLEWNSSSVRAEAKCVLYGVWHHGKHSFKETVLTALLQKVKCLPMYGQ NIVEYTELVTWLLGEFPDKSSKQQTEIVDHCLTPDVIRSIFETLHSQNELIANHPNSRIY NTLSGLVEFDGYYLESEPCVACSSPEVPYSRMKLESLKSETKFTDNRIIVKCTGSYTIQT VTMNVHDARKSKSVKVLNLYYNNRPVADLSELKNNWSLWKRAKSCHLAFNQSELKVEFPI PITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGTCSNCHENAYQCRQCRNINY DNLDSFLCNECGYSKYGRFEFNFMAKPSFTFDNMENDEDMKKGLAAIEAESENAHRRYQQ LLGFKKPLLKIVSSVGENEMDSQQKDSVQQMMVSLPGPSCKINRKIALLGVLYGEKCKAA FDSVSKSVQTLQGLRRVLMNYLHQKHSDNSGAASRFVISRSPNNCYGCAMTFVTQCLEIL QVLSKHQNSKKQLVASGILSELFENNIHQGPKTARVQARAALCAFSEGDINAVSELNSLI QKKVMYCLEHHRSMDIAVASREELLLLSEVCSLADEFWESRLRVVFHLLFSSIRLGAKHP AISEHIILPCLRIISLACTPPKPDTAEKEQGVVKSTSVMQQKDENNSTIFGSHGGGISSS KLMPEPMEKNWVASHKTQDIQLLSYSEWEKGASYLDFVRRQYKVSQSVKGVGQRSRPHRT DFLALKYGLRWKRSACKASKGDLSVFELGSWVTELVLSACSQSIRSEMCMLISLLCAQSS SRRFRLLSLLMGLLPATLAAGESAAEYFELLFKMIESEDARLFLTVRGCLDTICKLITKE VGNIESLERSLHIDISQGFILHKLIELLGKFLEVPNIRSRFMQDNLLTEVLEALIVIRGL IVQKTKLISDCNRLLKDLLDSLLLESSENKRQFIRACIRGLQIHGEEKKGRTCLFILEQL CNLICPSKPEAVYLLVLNKAHTQEEFIRGSMTKNPYSSAEIGPLMRDVKNKICHQLDLLG LLEDDYGMELLVAGNIISLDLSIAQVYEQVWKKSNSQSSNSMANSSLLSSGAVTSTRECS PMIVTYRLQGLDGEATEPMIKELEEDREESQDPEVEFAIAGAVREYDGLEILLCMIQRLR DDFKSNQEQLVAVLNLLMHCCKIRENRRALLRLGALGLLLETARRAFAVDAMEPAEGILL IVESLTLEANESDNISISQSVLTVTSEETGTGDQAKKIVLMFLERLCHPLGHKKSNKQQR NTEMVARILPYLTYGEPAAMEALIQHFNPYLQDWGEFDRLQKQHQDNPKDESISQQAAKQ RFTVENFVLVSESLKTSSCGERLKDIILEKGITGVAVRHLSESFAIAGQAGFKSSSEWAL ALKLPSVPLVLSMLRGLSMGHFATQRCIDEGGILPLLHALEGVSGENEIGAKAENLLDTL SDKEGKGDGFLGEKVRRLRHATRDEMRQRALRKREELLQGLGMRQELASDGGERIIVARP LLEGLEDVEEEEDGLACMVCREGYSLRPTDLLGVYSYSKRVNLGVGTSGSARGECVYTTV SYFNIIHFQCHQEAKRADAALKNPKKEWEGATLRNNESLCNSLFPVRGPSVPLAQYVRYV DQYWDNLNALGRADGSRLRLLTYDIVLMLARFATGASFSAECRGGGRESNSRFLPFMIQM ARHLLEQGGPSQRRNMAKTVATYISSSTLDSKSATGGTQPLGTEETVQFMMVNSLLSESY ESWLQQRRDFLQRGIYHAYMQHTHGRSTAKIESASSSKSPTSTSETGGDELLSIVRPMLV YTGLIEQLQQIFKVKKSSSLAATKGKSEGTSTGTEGEGLEGWEVVMKERLLNVKEMIGFS KELLSWLDDMTSASDLQEAFDIIGALGDVLSGGFSRCEDFVQAAIAAGKM NT seq 15273 nt NT seq  +upstreamnt  +downstreamnt atggcggatcacttaacgcgactctgtcaattcctcgccgaggagaagctctcgtcctcg tcttcatcgctcgatcttcttcttaagcttcgttccgatgagtcgatcaagctagggctc caacagttatacttgattcttcaaaccggcctccacccgatcgaacccggttcccatccc ttgtttaagtcttggtccgataatcagattctctccctcgcttctctgggttcctgtatt acctctgtctttcgatccctctcagtggaacaattggagccgataattgttgccgtggca aggaagttggtggaatttactgtttcttttttggggaaatcagacttcagtggcgacgat ttgagtgtacagagtaatatgatacagcttttggagattatattgggtggtggaactgac aaaatagttgattccttgcaacctgcctctgtaaatagccttgtggacttgttgccaata gtttcttgcaatttgggtagcattgagctggataacgacataaaatgtggccttcaaggg atgaagtgctcaagggcagagaagcaagtggatagacttctgtcggccttagcttctgaa tgcgtgcaacctgaaaggcatacttcagggtttgaggctcctagtttccatcaagatttg aacagtctagttttcctgtcccagcattgggcagttgctcatgcagaatgcattcggtct ttgattttgctgtgcaaagagcttgtggaacttcctgatatatttgatgaaaggatagca ggtgcaaatttccgcaagagactttccttcagcttgaggattttgaagtcacttggatgc cttctaaaggatgtgccatatgtagaatatgattcctcagtattagaagcaattgcttta tgtgctgatgttttgcctaatttgtttagacccagctttgaatttgtcaataacattgct gttacggacggtaattttgagagtcttgtactgtcactactagaagagtttattcatctt gttcgacttatgttctgcaacagcgtagtttttcagaatgtgcaagcatgtattgtagca tctattttggaacatctcggtccatccatttggagatacaacaaggcttcttcgaatata aagccccctttagcctacttccctcgaagtgttatttacaccctgaagctcattcaggat ctcagaatcgaattaaaagaggttgtagatctgaaggagcttgacacagaacttggtggt tctgttgatttatcaaaggattctcctttgtgccatatacatgctcagaaggttcccttg ctacagaggttcactatcgatgaactatcaaaaatgatatttccttcatcaagtaactgg atggacaatctgatgcatcttacttcttttcttcattctgaaggagtaaaattgaggcca aaaatggagaggtcaaccagttgtggaagatctaattgctcctcggaattggaaactgct gtttgccatgatgatgaagccctttttggtaatcttttctctgagggtagtcggacgtta ggatctgcggatgtatgtgatcaaacatctgctgtaagttctagctccagcaattgcaat atgccgatgcaagccgctatggaactgttgagctttctgaaagggtgcatcttctctcat gattggcttccttccgtttatgaggatgggtgcagaatgcttagtgtagaccacattgat atcttactttacatactcagctgtcaggggggaccttttgaagataactttgcagcttca catgaagataggaagagtgggcatatccaagagctttcttttcaacttctgcacaatctt cttacccaccatgcattgtctgattcacttgaggattatctagttgagcgaattctaaat gttgaagatgctgcctttgtttataatgatcagacgttagccttgctggctcatgcactt ttctctaaggtggactttgctggaagccagttgagaaccaaaatctacagaggatttgtt tcttttattgttgagaaggcaaaatctatttgctcagactgtcctactctgaaggaactt ctggtcactcttccatctgtatttcacattgagattcttctcatggcattccatttatca cctgatgaagagaaggtaaccctggcaaacttcgtattttctgcccttcagacggttcat gttccatccactggttcttatggtacacagctctcttgctgggcgttggtggtttcaagg ttgattctactgcttcgtcacatgatattacatccacgtacttgtccaccatcaatgctg ctagcttttcgatcaaagttgagggacatccaatcttttgcttctcatgtgccaacaaat tctattgatagtttttcctcgctggcatcaattgcagtaaagactttgacaggggctttg gttgatgaagagccaagctgcagtagcctgattcatcaactgattgatgttacatacatt cagtctccaatttacatggatgatgttgccattgggtcattacatttgagttgggatgat atgtgttcacgtttctcgtatattctggggttttggaatggtaaaaaagctgcagctatt gaagaccttattattgaaaggtatattttcttgctttgttgggatattcctaccatgaag tctccattaggtcatcagctttcactgtggagtaacctgcagtctctggaaatatctagc agagaacaatttttttgcttcagccatttacttctgggccagtgtgatgttattggcaag ggtgctgactttcaaaagcttgtggttggattgctagggcacttgcaggctgcacatttg caggataactttgagaatctaggatgggatttcttgagaaatggaatgtggttgtctttg gtactctctttttttaatgttggcattggaagatactgtgttaagaataacattcctgga ggtggtccaatctggacagagaacagacctagtgataatgattatatcaattctgctgaa ggcttcatttctggcttgattgcagataatcgaacttcagagcttttgaggatgtttgca tcctttttaaaaggatatttgcagttttatgagaaggctttccttgctacccttggtgat agcaagcatgatgactatatgttctcacctgtgctgcttctcaagctatctatgtttgac aaatccctcttggatgaactccttaagaagtgtgctgtggattcttttcaattggagtct gttcttgacatcttattaaaggtagatggagcagttgagaagagagcttctggcatttta gctaaggtattttgggaatgtatgttgcatggttttccttctcatcttcaagcttctagt ggaatccttctttcttgtattcttaacataaggaggattattttcactttggatggatta ctgaaactttccaatatgaaaggaaatattttcctggagattgatgtactgcatcaaatt cttgattcattgacaagtgtgaaattagatcgcatctttgaaaggcttcgtggaaaatgt gaagatgtttggctcaacttgaatgctggattggagctgtctgattatactgaattgttt ctactgaagcgcatggaaggatttctaagatatatccattctagagaaatgggtgacacc agtatccttgaatgggtaattaccaagacaatagataccatggatgccctcagaaaagat cctaagaagtctacacttttcaaattttatcttggagctggagatatgtctgaatcactt aaagagttgcatggctcggagcgtggtgatatattggttcttatcgactctgtgtgtaac tgtcacactgaattggttaacattaaggtgcttagcttctttattgatctcttatctgga gagctatgtcctaatcttaacctaaagatacagaataaataccttagcatggacttactg ttattgtccaagtggttggagaagaggttactaggttgcacagctgaagctatggatggg gtaaagagtgtcaaagcaaattctgtttctcttagagaatcaactatgagttttattttg tgccttgtgtcatcaccttctgaattacaatcagagctatacaatcatttgtttgaagct gtattgatctcacttgagactgcatttttgcaatttgacattcatactgcaaagtcatat ttccattttgttgttcaacttgcaaggggggagagctcaatgaagttgcttttaaagagg acggtaatgttgacgcagaaactggcaggtgaagagcgtttactaccgggattgaagttt atccttggctttcttggatgtttcttgagtgactgtgggtccagcagcaatacaacagaa aagtgttctgggaagtctctatccatcagtagtgttgccgtgggccctgtggcttctaga ccagtgggttccaggaagaattctgatgttttggttcttcctgcgaatcgagatggggca actgctactcttgagtgtgatgcaacttctgtagatgaagatgaggacgacggaacatct gatggtgaggaagctagcatagataaagatgaggaagaggataccaacagtgaaagggct cttgcttctaaagtttgcacattcacttctagtggcagcaatttcatggagcaacactgg tatttttgttatacctgtgatctgacagtatcaaaaggctgctgctctgtttgtgctaaa gtttgtcatcgtggtcatcgtgttgtttactctcgctccagtcgatttttctgcgactgt ggagcaggtggtgttaggggtagtagttgccaatgcttgaagcctcgaaaattcactggt agtgatagtgcccttaattgtggtaccaacagttttcagtcctttttacctctcacagag gatacagatcagctgccagaaagtgattccgatatggatgaggatgttggggcagatatg gaaaactcgctgaggttgtctattccaaaagatctgcaagatgggatctccatgttgctt gaagaacttgatgttgagcgtcaggtgcttgaactatgctctacattgctgccttctata acaggcaggagggaatccaacctttcaaaagataagaaaattattctgggtaaagacaaa gtgctttcttatggcatagatctcttgcaattgaagaaggcgtataaaagtgggtccttg gatctgaagataaagactgattattcaaatggcaaagaacttaaattgcatttagctagt ggttctcttgtcaaatccttgctcagtgtcagtattagaggaagacttgctgttggagaa ggcgacaaagttactatttttgatgttgggcagttaataggacaagccactattgcacct gtaacagcagacaaggccaatctcaaggctttatccaagaacctcgttcgatttgaaatt gttcacctttcatttaatcttgtggttgagaattaccttgctgtggctggctatgaagat tgccaggttcttactttgaatcctcgtggagaagttactgatcgtctagcccttgagctt gccctgcaaggtgcttatatcagacgcatagaatgggttcctggttctcaggttcagtta atggttgttactaacaggtttgtcaaaatatatgatctgtcccaagacaacatcagtcca atgcattactttacattggcagatgacacaatagtagatgcaacacttattgtggcctct cagggaaggatgtttcttgttgtcctttcagaacgagggagtttatttaggctgggatta tctttggagggtcatgtgggagctacacctttgaaggaaataattcgtattcaggacaga gaaattcatgcaaagggctcatctttgtacttttcttctacttataagttacttttcttg tcctatcaagatggcactactttgataggtcggttaagtcctgatgcgtcatcattgact gagatatcttgtgtctatgaggaacaagatggtaagctgcgaccagctggactgcatcga tggaaagagttactggttggtagtggattattctgtggcttctcaagtgtgaaatcaaat tctgctattgcagtatcttttggtgcagatgagttatttgcacagaatttgaggcatgcc gtgagctcttccttgcccttagtgggaataactgcatataagcctttgtccaaagacaaa gtccactgtcttgttttacatgacgatgggagccttcagatatactctcatgttcctatg ggagtggatgctgctgctagtgccacagctgagaaagtgaaaaaattgggttctaatatc cttaataataaagcttatgctggcacaaagccagaattcccccttgacttctttgagaag acagtttgcattacagcagatgtgaaactgagtggtgatgcaatcaggaatggtgattct gaaggagctaaacagagcttggcctcagaggatggttttctggaaagtccaagtcccgca ggatttaagatatctgtttccaattcaaaccctgatattgtcatggttggttttcgtgtt tatgtgggtaatcaatcagcaaaccatataccttctgagattaccatcttccagagggtg attaagcttgatgaaggcatgaggtcctggtatgacattccatttaccgtagctgaatca ctacttgctgatgaagaattcatcatttctgttggtccaaccttcagtggctcagcccta cctagaatagactcacttgaagtttatggtcgagctaaagatgaatttggttggaaggag aaaatggatgctgtgttagacatagaagctcgtgttcttggtgctaattctgtgcttgca gggtctggtaaaaagagccggtcaatgcagtctgctcctattcaggaacaggtggtggct gatggtcttaagcttctctctaggatttactgtctatgcagatcccaagaagaggagcta aaagttgatctgagcaagctaaagagcaagcagttattggaagcaatatttgagagtgat agggaacccttgatgcaggctgctgcttgccgtgtcctgcaggctgtgtttcctaaaaaa gagatatactaccagatcaaggacaccatgcgtcttcttggcgtggttaagtcaacatct attctttcgtcaaggcttggaattggtggtgctacaggacagtggcttattgaagagttc accgcccagatgcgcgcagtgtctaaaattgcacttcaccgtcgctccaacttagctaat ttcttggagatgaatggttctgaagtggtggatgggcttatgcaagttctgtggggaatt ttagatttagaacttcctgacacacagacaatgaacaatattgtgatatctgctgtggag ctcatttacagctatgctgaatgtttggctttgcatgggaaggacacagggaggcgctct gtggcgcctgcagttatattatttaaaaaacttctcttcttcccaaatgaggcagttcaa acttcaagcagtttggccatatcatcaagattgctccaggttccatttccaaaacaaact atgttaggaactgatgatgtggtagaaagtgcggtaacgtcctctatgcctgctgataca tctgatggaaatacacaagtcatgattgaagaagattctataacgtcatccgttcaatac tgttgtgatggttgttctactgttcccatactaaggcggagatggcattgcactgtttgt cctgattttgacttatgcgaggcatgctatgaagttctagatgctgataggcttcctgca cctcattctagagatcatcctatgaccgcaattccaattgaagtggaatctcttggagga gatggcagtgaaattcgcttctctacagatgatttgagtgattcaaacttggtgacaaat gtaacagatgttggtatgcagacttctgcaccttcaattcatgtcttggaaccaagtgaa tccatggagttctcttcttcaatggctgaccctgtctcaatttctgcttcaaaacgagct gtaaattccttgcttctgtctgagcttcttgagcagctgaaagggtggatggagaccact tctggtattcgagctattcctgttatgcaacttttctacagattatcatctactgttggt gggcctttcattgatagttcgaagtccgaaaccttagatttggagaaattaattaaatgg tttttgaatgaaattaacctcaacaaaccttttgtagccagaacacgttcttcttttgga gaagtggcaatcctagtcttcatgttcttcacattgatgctccgaaactggcaccagcct ggtagtgatggcactgcttcaaaaggaactgggaatacagacactcctgataaaagtggt tctcaagtctccggttcagttgcctctccgtcttccttggtggatcatgacaaaaatgac tttgcatcccaacttcttcgagcttgcaattctcttaggaaccaagcttttgttaattat ataatggatattctgcagcagctagtgcatgttttcaagtcaccagcagctggtcttgaa aatgctcatggttcaaatgttgcttctggatgtggggctttattgacaatccgaagagat ctacctgctggtaatttttcccccttcttttcagattcatatgccaaagctcatcgggca gatacttttatggactaccacaggctattgctagagaatgcatttcgactggtatacact ttggtaagaccagaaaaacatgacaagaatggggagaaagaaaaggttcctaagacatcc tctggtaaggatttgaagcttgatggatatcaggaagtcctctgcagttatataaataat cctcatacaacatttgtgagaagatatgcaaggaggcttttcctgcatatgtgtggaagc aaaactcactattacagtgttcgggactcttggcaattctctactgaagtgaagaaacta tacaaacatgtaaacaaatctggtggatttcaaaatcctgttccgtatgaaagaagtgtt aagatagttaagtgcctatccaccattgctgaagtggctgctgcccggcctcggaactgg cagaagtattgcttgagacatagtgacgttttgccttccctaatgaatgggattttttat tttggtgaggagtctgtcattcagactcttaaattattaaatttggcattctatttaggg aaggatatgagtcactcatcgcaaaaagcggaatctggggattcaggtaccacttcaaac aaatcaggcacacaatctttggattcaaagaagaagaagaagggtgatgatggagttgaa actggtttagagaagtcttttgtggatatggaaatggtagttgaaatctttactgataag ggaggtgatgtcttgaggcaatttattgattgctttttactggaatggaactcgagctct gtacgtgctgaagctaagtgcgttctttatggcgtgtggcatcacgggaaacattcattc aaggaaactgtgttgacagctctcctgcaaaaggttaaatgcttgccaatgtatggtcag aatattgtggagtatactgaacttgtcacttggttactgggtgaattccctgataaaagt tcaaaacaacagactgaaattgtggaccactgcttgacccctgatgttatcaggagtata tttgagacacttcattcacaaaatgaactcatagctaatcatccaaattctcgcatatac aacaccttgagtggtctggtagaatttgatggttactatcttgagagtgagccgtgtgtt gcctgcagctctcctgaggtcccttacagcagaatgaagttagaaagtttgaaatctgag accaagtttactgacaaccgcatcattgtgaaatgtactggaagttatacaatccagact gtgactatgaacgttcatgatgcccgtaaatctaagtcagttaaagtcctgaacctgtat tacaacaatcgacctgtggctgacttatcagagttgaaaaataattggtcattatggaag cgtgcaaagagttgtcatcttgctttcaaccagagcgagctcaaagtggagttccccatt ccaatcactgcttgtaacttcatgattgagcttgattctttctatgaaaatcttcaagcc ttatcccttgaaccattgcagtgtcctcgttgcagtcgacctgtgactgataagcatggg acttgcagtaattgccatgaaaatgcatatcaatgcaggcagtgccgtaatatcaattat gataatctggattcttttttatgcaatgagtgtggatacagcaagtatggtcggtttgag tttaacttcatggcaaaaccaagttttacatttgacaacatggagaatgatgaagacatg aagaaagggctggcagctatagaagctgaatctgaaaatgctcataggagatatcaacaa cttctgggcttcaagaaaccccttctgaagattgtctctagcgtcggtgaaaatgagatg gattcacaacagaaagactctgtccagcaaatgatggtttccttgcctggtccttcatgt aagataaaccgcaaaattgctcttctaggtgttctttatggtgagaagtgcaaagctgct tttgattctgtcagtaaaagtgtacagacactgcagggtcttcggcgggttttaatgaat tacttacaccagaagcattcggataattctggagctgcatcaaggtttgtgatttccaga tccccaaataactgctatggttgtgcaatgacatttgttacacagtgtcttgagatccta caggtgttatcaaaacatcaaaattctaagaaacaacttgttgcatctggcatcttgtct gaattgtttgaaaataatatccaccaaggtcctaaaactgctcgtgtccaagcgagggca gccctttgtgctttctctgaaggtgatattaatgctgtatctgagttgaacagtttgata cagaagaaagtaatgtattgtcttgaacatcatcgttccatggacattgctgttgcctct cgtgaggaattgttattgctttccgaagtgtgttccctggctgatgaattctgggaatca agattgcgtgttgttttccatctgttattttcttccataagattgggtgcaaagcatcct gccatatcggagcacataattctcccttgtttgaggattatatctttggcttgtactcct ccaaaacctgatactgcagaaaaggagcaaggtgttgttaaatctacttcagttatgcag cagaaggatgaaaataactcgactatatttggatctcatggtggtggtatcagctcaagt aaactaatgccagaacctatggaaaaaaattgggttgcttctcataagacccaagatatt caattgttaagttattccgagtgggagaagggggcatcttatcttgattttgtccgaagg caatataaagtgtctcaatctgtcaaaggtgtgggccagaggtcacgcccacatagaact gacttcctggccctcaaatatggactaaggtggaagcgctctgcttgtaaagcaagcaaa ggtgacttgtcagtgtttgagctaggatcatgggtcacggaacttgttctgagtgcgtgc tcccagtccattaggtctgagatgtgtatgctaattagtttactttgtgctcaaagttca tcaagacgatttcggttgctgagcctattgatgggtttgttaccagcaactcttgctgct ggcgaaagtgctgcagagtattttgagttactattcaagatgattgaatcagaagatgct cgtcttttcttgacagtaaggggatgtctagatacaatttgcaagttgattaccaaagaa gtggggaatatcgaatcacttgagaggagcctgcatattgacatttcacaaggattcatt ctccataagcttatagagctccttggaaaatttctggaggttcctaatatcagatcgaga ttcatgcaagacaatttgctgactgaagtccttgaggctcttattgtaattcgtggtttg atagtgcagaagactaagttgattagtgattgcaaccgacttctaaaagatcttttagat agtctgctgcttgagagcagtgagaacaaacggcaattcatccgtgcgtgtatccgtggt ctgcagattcatggtgaggagaagaaaggaagaacatgtttgtttattttagagcaactc tgcaacttgatctgcccatcaaaaccagaggcggtttatttgttggttctaaacaaagct cacacgcaggaagagtttattaggggatcaatgactaagaatccttattcaagtgctgag attggtccactaatgcgtgatgttaaaaataaaatttgccatcaattagatctgctaggt cttcttgaagatgactatggcatggaactcttagtagccgggaatataatctctcttgat ttgagcattgcccaggtttatgagcaagtctggaagaagtcaaacagtcaatcttctaat tctatggctaattcttcactgttatcctctggtgctgtaacatcaactagagaatgctct cccatgatagtgacataccgacttcagggtttagatggtgaagccactgagcctatgata aaagaattggaggaagacagagaggaatcacaagatcctgaggttgagtttgcaatagct ggtgcagttcgtgaatatgatgggctggaaatcttgttgtgcatgattcagcgtttgcga gatgacttcaagtccaaccaggagcagttggttgctgttctcaatcttctcatgcattgc tgcaagattagagagaataggagggccttattaaggcttggagctttaggcttactgctt gaaacagcaaggcgagcttttgctgtggatgccatggagccagctgaaggcattcttttg attgtagagagccttacattggaagcaaatgagagtgacaatattagtatctcacaaagt gttctcactgtcactagtgaggaaactggcactggagaccaagccaagaaaattgttctt atgttcctggaaaggctgtgtcatcctttagggcataagaaatcaaacaaacaacagagg aacaccgagatggttgcaagaatcttaccctacttaacttatggtgaacctgctgctatg gaagcacttattcagcattttaacccatacttgcaagactggggagagttcgaccgattg cagaaacagcatcaagacaatcctaaagatgaaagcatttctcagcaagcagccaagcag aggttcacggttgaaaattttgttctggtttcagaatctctaaaaactagttcctgtgga gagagattgaaggatattatcctcgagaagggcattacaggtgtagctgtcagacatttg agtgagagttttgcaattgcagggcaggctggctttaaatccagttcagaatgggcatta gctttgaaactgccatccgtcccacttgtattgtcaatgctcagaggcttatcaatgggg cactttgccactcagaggtgcattgatgaaggtgggattttgcccttactccatgctttg gaaggtgtgtctggagaaaatgagattggggcaaaggcagaaaatttgctggacactcta tcagataaggaaggcaaaggagatggattcttgggggaaaaggtgcgtaggttgcggcat gcaactagagatgaaatgagacagcgagctttaaggaaaagggaagagttgcttcaggga cttggaatgcgacaagagctagcttcggatggtggtgagcgaattattgttgctcggcct cttctggaaggtttggaagatgtggaggaggaggaagatgggctggcgtgcatggtgtgt cgagaaggctatagtttgagacccactgacttgctgggtgtttattcttatagcaagcga gtaaacctgggtgttggcacgtcaggaagtgcacgtggagagtgtgtttacactaccgtt agttattttaacattattcatttccagtgccatcaagaggctaaaagagcagatgctgct ctgaagaatccaaagaaagagtgggagggtgctactctcaggaacaatgaatcgctttgc aattctttatttcctgtgagaggtccgtcagttccattagcacagtatgtccggtatgtc gaccaatactgggataacctcaacgctcttggtcgtgctgatggaagtcggcttcggcta ttgacttatgatattgttctgatgctagctcgatttgcaacaggggcatcattcagtgca gagtgcaggggcggtggaagagaaagcaactcccgctttttgcctttcatgatccaaatg gctcgtcaccttctggaacagggaggcccttctcagagacgtaacatggccaagacagta gcaacatacatatcctcttcaacattagattcaaaatctgcaaccggtggaactcaacct ttgggaacagaggaaaccgttcagttcatgatggtaaattcactgctttcagagtcctat gagtcatggttgcaacagcgacgtgacttcttgcaacgtggaatatatcatgcctacatg cagcatactcatggccggtcaacagctaagatagaatcagcaagtagcagcaaaagtccc acctccacctcagaaaccggtggtgatgagctactgtcaattgttcgacccatgctggtg tatacaggcttgattgagcagttgcagcaaatattcaaggttaagaaatcatcaagtttg gcagccaccaaaggcaaatctgaaggaacctcaaccggaaccgaaggagaagggttggaa ggttgggaggtggtgatgaaagagaggttgttgaatgtgaaggaaatgatagggttctcc aaagagttgctctcatggctcgatgacatgacttctgcaagtgatttgcaagaggctttc gacatcattggtgccttgggtgatgttttatcgggtggattttcccggtgtgaggatttt gtccaagctgctattgctgcaggaaaaatgtga

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