Gymnodraco acuticeps: 117540448
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Entry
117540448 CDS
T09661
Symbol
brca2
Name
(RefSeq) breast cancer type 2 susceptibility protein isoform X1
KO
K08775
breast cancer 2 susceptibility protein
Organism
gacu
Gymnodraco acuticeps
Pathway
gacu03440
Homologous recombination
gacu03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
gacu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
117540448 (brca2)
03460 Fanconi anemia pathway
117540448 (brca2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
gacu04121
]
117540448 (brca2)
03036 Chromosome and associated proteins [BR:
gacu03036
]
117540448 (brca2)
03400 DNA repair and recombination proteins [BR:
gacu03400
]
117540448 (brca2)
Ubiquitin system [BR:
gacu04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
117540448 (brca2)
Chromosome and associated proteins [BR:
gacu03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
117540448 (brca2)
DNA repair and recombination proteins [BR:
gacu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
117540448 (brca2)
FA (Fanconi anemia) pathway
Downstream FA components
117540448 (brca2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
BRCA2_TR2
Tower
RF-1
Motif
Other DBs
NCBI-GeneID:
117540448
NCBI-ProteinID:
XP_034063014
UniProt:
A0A6P8TGE9
LinkDB
All DBs
Position
Unknown
AA seq
2982 aa
AA seq
DB search
MELTLPSKHIYDTYKDEIWKELGPLDPDWFESLAAQTFTNEGHFYDQDDLCANQEGNFKT
PLDKSAVESQLFSTPKAFRRIRVVSPETGDDHSFTGEQERETLPWTTTQSPCLFQMSKWD
PGARNGRYQRFDPLHTPHESPVSYSKHISEGLRVQIHSDILWTSSLNTPPAEASTLILTK
ADESPCPVGVSAEQDVVFVRKLFPSLSNLSKVEVVSPKNNGIPSVAQGVVSPVAGLDPES
HHSPQSSLNLSDSGWKQKLPDAIEDGDIRKTEASVLNGAEHVLSIFFSNSSSALRKVKSE
RIKRKQIIPTREHGCCSTDISSTNDKQRTADQEPGRLPSSPPVKTGDVGITQWSPLSLSE
IPPSTVEASCYDSTPATQVGNIILTEELRSHSGQLVRPLLKLTDSGFTKKKRTFIYTVGT
SKPQVHGEGKRTQKIDSSPVIPDYGNKVNVTQSGKSQDEAYYCSMGKNEMQKWGNLAEDI
LPPSVQAKVQDLDMSQLCKEFAQDFSQSSDPRKLSKVAEDTPGNGFSPSACLSAVKRAKQ
KAIQAKLHHDCDGDSDSGFQYTDFTRITASSFVHPSSEINDQSKPMPGFTSDIGKIPPFT
STNKGNDKDVLQETEMDAKLSSATKESQTLVPGRAIKLHTESTSAQLPSGAKGTEDITYG
IPFNGQACSSLPEKTTVSLPSVHASGFKTSSNKGIHISLANLQRAKHLFEETEGEKTQCD
QPSKCVLDNKKEMSCGSVKNPTTNSNNPTSSSETKEDISCQLTASQKADVTELCTLLEEA
DSQFEFTQFKTAKVKQHSQDKTTSPKKVEKEFDPDSLSGIDFDDSFSSEEKHLAVTVMYE
KRDLVPDSKTNGYTPNITSKSTGLLLSSAIKNENSSTEVASTTKGPRLILSTDHKTLDRA
LLTDTSKLENNNPLLGVGFKTAGGNNLKVSKKCLSKARALFADLEENLVTSQTSPDKLRR
DPRTQHKTTVDNRKDSSLHDKLKESVCSEKLVTSIRDENAAQSFENIKMDTTSQRGFQMA
CGKGITITAKARSQQEADVFFEDTMDFNDGLSVKHQKSTVPLPGSVSHNETLLNCKGIKV
TVPEELINNPEHVNAGPAAPHTDVQQNVKILNVGFKNAPSFGDYAPFHENPSTAKALSSL
SCTTSTSTGSSAINKSSNDVGFFTASGKKVSMSADALKKAESLLNEMNPLEDANQQLKQQ
GDALRTGHLTNNHIQVTAPKNCGFQTASGKGVAISSTALKKAKMLLSECDEVVDEINVTP
ARSTMPVPGPQLGKSGFPAGGSKPVAFSYEAIQKAKALFSDVSFSTEIPAVSDTMNRENK
QGNAENTKEMHCGFTTAGGAKVHVSHTNLLKAKHLLTEFNDGPISTRAMQEADTLFKDCD
FMNRNNGRPVKQKRSIEPVSGSSSKKKNLSHFKQDEKMTINISEEPRIQNLPLVVNHEKM
QHPHDVETHKDDFKKTLDSIEVASLHGNPSLMSKPLSPALCTTSKNISSSAVNGLGKGGG
FCTASGKKVSVSDSSMTKAKSLFNESAIFEDTNKQKEGTFLPMNGGFQTASGKGVTISSS
ALKKATTLLSDCEGVEDTPEHCKPPVPWPPPRSNGFLAASGKSVAFSSEALQKARALFSD
ISFSTEIPAVSDTRNSDKQQGHDEKPEKIHCGFTTAGGTKVNVSRKNLLKAQNLLAEEAD
GKCHSSNSYSTCPQDTNKPDPSKVIDVKQTCKPSTDSGKDMPTGFCGPLVFKSSTSLQNP
EQENESLRNPSLPDCISFQDEAHTDTFQLKGTTSPASAGNLHDSPEEEMSIGLDYETNRT
SNSKGCMVKRPQESSVLNAQSLHLSGCTETQQKFFAQEALDCTKALLDDESLAGQSLSMT
LENMPLQENPKSSFRSAERKGTGKRSVEDSDIAGQPPLKRRLLEEFDRTVDDPKGSTLCP
ETSCPKGVMKDRRVFKYSVSLHPNITKPPGGKNDIETRLQKMTPTQPSIPGDSRSSHPKM
PAFVPPFLRNAKTESHKNGVLKVNQGTPSAFVPPFKKQRTIVQESSSKPQEEEDNNLHLF
VTPFCSNTFVPTAKKTQSTTDVTGNKSKEDIQTVSLAGTTNISLNGQNVAVGCGSEDSSA
EASQVEDILSPSQDIFQNFPNVELARDVQDMRIRKKKRQTIRPLPGSLFLTKTSGGSRIP
LKAAVNGKPPAIYTQKQLYGHGVHQHVCEITSETAESFRFNLQQFIRREALIEGGGVQLA
DGGWLVPSKDGTAGKEEFYRALCDTPGVDPKLMSEAWAYNHYRWIVWKQASMERSFPESM
GSLCLTPEQLLLQLKYRYDVEVDHSRRPALRKIMEKDDTSAKTLVLCVCGVVSRGHSTNR
QSFSDTKTPPDAEAKVENPSAVVWLTDGWYAIKAQLDEPLTAMLHKGRVAVGGKLIIHGA
QLVGSQDACSPLEAPESLMLKICANSSRPARWDTKLGFHKDPRPFLLPISSLYSNGGPVG
CVDIIILRSYPIQWMERKTDGGAVFRSVRAEEKEARQHDSNKQKAMEILFAKIQAEFEKE
DKGNSRPQRRRRTISRQIIAGLQDGEELYEAVGDDPAYLEAQLSEQQLETLRSYRCSLME
KKQADLQDRFRQALENAEESEGSCPKRDVTPVWRLCLADLMDQPGRVYQLNFWRPSSDLQ
SLLKEGSRYKVYNVTTSDRKKHVGNTTVQLTGTKKTQFQDLPVSQEWLSTHFQPRVSTHF
VDLQNTELQPQCGEVDLTGYVISIVDGQGFSPAFYLTDGEMNFIKVRCFSSFAQSGLEDL
VKPNVLLALSNLQLRGQSTSPTPVVYAGDLTVFSTNPKEVHLQKSLCQLRKLAQGQDSFF
TIAEEKLSHLGKSDGTSSFSSPALQTRNTAFTTVRRLDTYTSVTSQQPVRSLGSFTPVSR
KPPAANCSTEKDPNSLKKRRALDYLSRIPSPPPLSPFGPVASPCVNTTFNPPRRSGTGTP
STLKTVQTPAQTPVETPVEDEWVNDEELAMIDTQDLHVADLL
NT seq
8949 nt
NT seq
+upstream
nt +downstream
nt
atggagttaacgttaccctctaaacacatttacgacacatacaaagatgaaatctggaaa
gagctgggccctctggaccccgattggtttgagtccctggcagctcaaacgttcaccaac
gagggacatttttatgatcaagatgacctgtgtgccaatcaagaaggaaactttaaaaca
cctttggacaaaagtgcagtagagagtcagctgttttcaaccccaaaagctttcagacgc
attcgagttgtgtcacctgaaactggggatgaccattctttcaccggtgaacaagaaaga
gaaacattgccatggacgacaacacaaagtccttgtttgtttcagatgtcaaagtgggac
ccaggtgctagaaatggaagataccagagatttgatccacttcataccccacacgaatcc
ccagtcagctacagcaagcatatatctgaaggtctcagagtacagattcattctgatatt
ttatggaccagttctctgaataccccaccagcagaagcatccaccctcattttaacaaaa
gctgacgagagtccctgtccagtaggtgtttctgcagaacaagatgtggtttttgtacgg
aagcttttcccttctctttcaaatctatctaaagttgaagtggtgtcacccaaaaacaat
ggtataccttccgttgctcaaggtgttgtttctcctgtggctggtctggatccagagtcc
caccactcccctcagagttcactgaatctaagtgacagtggttggaaacagaagctacca
gatgctattgaggatggagatattcgcaaaacagaagcaagtgttcttaatggagctgaa
catgttctctctatatttttcagtaacagtagttcagcactgagaaaagtcaaatcggaa
agaatcaaaagaaagcaaatcattccaaccagagaacatggctgctgctctacagacatc
tcatcaacaaacgataaacagagaacagctgatcaggaacctggcagacttccttcatca
ccacctgtaaaaactggagatgttggaattacccagtggtctccgttgagtttatctgaa
attccaccttctactgtggaggcttcttgctatgatagtactcccgctacgcaagtggga
aacattattttaacagaagaactgcggagtcattctggccagctagtcaggcctttgttg
aaacttacagactctggatttactaagaaaaagaggacatttatttacactgttgggact
tcaaaaccacaagttcacggagaaggaaaacggactcagaagattgactcatccccagtg
attccagattatggaaacaaagtaaatgtgacacagtcggggaaatcccaagatgaagca
tactattgcagcatgggaaagaatgagatgcaaaaatggggaaatctcgctgaagatatt
cttcctccctctgtacaagcaaaagtccaggatcttgacatgtcgcagctttgcaaagaa
tttgcacaagacttcagtcaatcgtcagacccccgtaaactgagtaaagtagcagaggat
actcctggaaatggcttctctccatcagcttgtctgtcagctgtgaaacgagctaaacag
aaagcaatacaagcaaaacttcaccatgactgtgatggtgacagtgacagtggattccag
tatacagatttcactcgcattactgcatcatcatttgttcatcctagctcagagattaat
gatcaaagtaaaccgatgcctggttttacatctgatatcggcaagatccctcctttcaca
tctacaaataaaggaaatgacaaggatgttttacaagaaactgaaatggatgccaagctg
tccagtgcaaccaaggaaagccagacactggttcctggcagagcaattaagttgcacaca
gagagtacatcagcacaactacccagcggggcaaaaggaactgaggatatcacttatggc
attccctttaatggtcaagcttgtagcagtctgccagagaaaaccacagtttctcttcct
tccgtgcatgcatcaggatttaaaacatcttcaaataaagggatacacatttccttagcc
aacctacagagagccaagcatctatttgaagaaactgagggggaaaaaacgcaatgtgac
cagcccagcaagtgtgtccttgacaataagaaagaaatgagttgtggatcagtgaaaaat
ccaaccaccaactcaaacaacccaacttcttcaagtgaaacaaaagaggatatcagttgc
cagttaacagcttcacaaaaagctgatgtgactgagctttgcactctcttggaagaagca
gatagccagtttgaatttacacagtttaaaactgcaaaggtgaaacaacacagtcaagat
aaaactacctctcccaaaaaagttgagaaagaatttgaccctgattcactttcaggtata
gattttgatgacagttttagttcagaagaaaagcatctggcggtaacagtaatgtatgaa
aaaagggacttagttccagatagtaaaacaaatggttatacacccaacattacaagtaaa
tccacaggtcttttattgtccagtgcaatcaaaaatgaaaactcctcgactgaagttgcg
tctaccactaaaggcccaaggcttattctttcaactgatcacaaaacccttgacagagcc
ctgctcacggacacaagcaagctggagaacaacaaccctttacttggtgtgggatttaag
actgcaggaggaaacaatttgaaagtttcaaaaaagtgtttgagcaaagctagggctttg
tttgcagatttagaggagaatcttgtgacaagtcaaacctcaccagacaagctgagacgg
gatcctaggacacagcacaagactactgtggacaatcgcaaggattcatctttgcatgat
aagttgaaggagtctgtctgttcagaaaaactggtcacaagcataagagatgaaaatgct
gcacaaagttttgaaaacatcaagatggacaccacgtctcaacgtgggttccaaatggcc
tgtgggaaagggattactatcacagcaaaagctaggagtcagcaggaggcagatgttttc
ttcgaagacactatggactttaatgatggcctatcagtaaaacatcagaagagcactgta
ccgttgcctggaagtgtcagtcataacgagacccttctaaattgtaaagggataaaagta
actgttcctgaagaactgatcaataaccctgagcatgtgaatgctggaccagctgcaccc
catacagatgtacaacaaaatgtaaagattctaaatgttggttttaagaacgcaccgtct
tttggagattatgcccctttccatgaaaacccttcgactgcaaaggcactttcatctctt
tcatgcacaacatctacgagtactggctcctctgccatcaataaatccagcaacgatgtt
ggattttttacagccagtggaaagaaggtatctatgtcagctgatgcactgaaaaaagca
gagtcccttttgaatgaaatgaatcctcttgaggacgcaaaccaacaactgaaacaacaa
ggagatgctttaagaacaggtcatctcaccaacaatcatattcaggttacagcccctaaa
aattgtggatttcagacagccagtggcaaaggagtggccatttcatctacagctctcaag
aaagcaaaaatgttgttgagtgaatgtgatgaagttgtagatgaaatcaatgtgacacca
gcacgttcaacgatgccagttcctggtccacaacttgggaagagtggatttcctgcaggc
ggcagtaagccagtggcattttcttatgaggccatccagaaggcaaaagctctcttcagt
gacgtcagtttcagtacagagatcccagctgtttcagacaccatgaatagagaaaataaa
caaggcaatgctgaaaatacaaaagaaatgcattgtggttttacaactgcagggggagct
aaagtccatgtttcacatacaaatctattaaaagcaaaacacctcttgacagaatttaat
gatggtcctatttcaacaagagcaatgcaagaggcagatactttattcaaggactgtgac
tttatgaatagaaacaatggcaggccagtaaaacaaaagagaagtatagaacctgtgagt
ggaagcagcagcaagaagaaaaacctttcacattttaaacaagatgaaaaaatgaccata
aacatttctgaagaacctagaattcaaaatctgccattagttgtgaaccatgaaaagatg
caacatcctcatgatgttgagactcacaaagacgattttaagaaaacactggattctatc
gaagttgcttctttacatggaaacccatctttgatgtcaaagccgctttctcctgcattg
tgcacaacttcaaagaacattagttcctctgcagtcaatggattgggcaaaggtggtgga
ttctgtacagccagtggcaaaaaagtatccgtgtctgatagctcgatgacaaaagcgaag
tctcttttcaacgaaagtgctatatttgaggacacaaacaaacagaaagaaggaactttt
ctaccaatgaacggtggatttcagacagccagtggcaaaggggttaccatttcatcttca
gcactaaagaaggcaacaactctgttaagtgactgtgaaggagttgaggatacaccagaa
cattgcaagcctccagttccttggccgccacccaggagtaatggatttcttgcagccagt
ggtaagtcagtggcattttcttctgaggccctccagaaggcaagggctctcttcagtgac
atcagtttcagtacagagatcccagctgtttcagacacaaggaacagtgataagcaacaa
ggccatgatgaaaaaccagagaaaattcattgtggttttacaactgcagggggaacaaaa
gtcaatgtgtcacggaaaaatctattgaaagcccaaaaccttttagcagaagaagctgat
gggaagtgtcattcttcaaactcatactcgacatgccctcaggacactaataaaccagat
ccatcaaaggttattgatgtgaaacaaacatgtaagccttcaacagacagtggcaaggac
atgcctactgggttttgtggcccgctggtattcaaatcctcaacctctttgcaaaatcct
gagcaagaaaatgaatctcttcgaaatccaagtctacctgattgcatttcttttcaagac
gaggcacatacagatacatttcagttaaaaggcacaactagcccagcatcggctggcaac
ctccatgacagccctgaagaggaaatgtccattggtttggactatgaaacaaatcggaca
agtaacagcaagggatgtatggtcaaaaggccacaagagtcttctgttttaaatgctcag
tcacttcacctaagtggctgcactgaaacccagcagaagtttttcgcccaggaagctctg
gactgcactaaagctttgttagatgatgaaagtctagctggccaaagtctctcaatgact
ttagaaaacatgccactgcaagaaaacccaaaatccagcttcagatctgcagagcgaaaa
ggaacagggaaaagatcagtagaggactcagatatagctggtcagcctcccctgaaaagg
cgattactggaagaattcgacaggactgttgatgatcccaaaggttcaacactctgtccg
gagacaagttgtccaaaaggtgtaatgaaagaccgaagggtttttaaatacagcgtctct
ctccatccaaacattacaaagccacctggtggaaaaaacgatattgaaaccagattgcaa
aagatgacaccaacacagccatcaatcccaggagacagcagatcatcacatcccaagatg
ccagcgtttgttcctccattcctcaggaatgcaaagacagagagtcacaagaatggagtg
ctcaaggtcaaccaaggaacaccttctgcatttgttcctccattcaaaaaacaaagaact
attgtccaagagagctcctctaaaccacaagaggaggaagataataacctccatctcttt
gtaacgcccttctgcagcaacacttttgtgccaaccgctaaaaaaacacagagcactaca
gatgtaactggtaataaaagcaaagaagacattcagacggtgtccttggctggcactaca
aatataagtcttaatggtcaaaacgttgctgtgggctgtggatcagaggactcttctgcc
gaggcgtcacaagtggaagatatattgtccccaagccaagacatatttcagaattttcct
aatgttgagctggcacgagatgtgcaagatatgaggatcaggaaaaagaagcgccagacc
attcgacctttgccgggaagtttgtttcttaccaaaacctcaggggggtcgagaataccg
ttaaaagctgcagtaaatggaaagcctcctgcaatatacacccaaaagcagctgtatgga
catggagttcatcagcacgtgtgtgagatcaccagtgagactgcagaatccttccgcttc
aatttacagcagttcatcagacgggaagcattaatagaaggaggtggtgtgcagcttgcg
gatggaggatggctagtccccagcaaggacgggactgcagggaaagaagagttttataga
gcgttatgtgacacacctggtgttgatcctaaactaatgagtgaggcgtgggcgtacaat
cactaccgatggattgtgtggaagcaagcctccatggaaagatcatttccagaatcaatg
ggcagtctctgtctcactccagagcagcttctccttcaactgaagtacagatatgatgta
gaggtggaccacagccgcagaccggctctgagaaagatcatggaaaaggacgacacatca
gccaaaaccctggtcctgtgtgtgtgcggggtcgtctccaggggccactccacaaaccga
cagagtttcagtgacaccaagactcctccagatgctgaagccaaggttgaaaacccatct
gcagttgtgtggctgacagatggatggtacgccattaaagcccagctggatgaacctttg
actgccatgctccacaaaggtcgagtggctgtgggggggaagctgatcatccacggggct
cagctggtgggatcacaggatgcttgctctcctctggaggcacctgaatctctcatgtta
aagatatgtgccaacagcagccgtcccgcacgatgggatactaaactgggatttcacaag
gatccacggccattcctgcttcctatctccagtttgtacagcaatggaggaccggtagga
tgtgtggacattattatcctgagaagctaccccatacagtggatggagaggaaaacagat
ggaggggctgtgtttcgctctgttcgtgcagaagagaaggaggcgaggcaacacgacagc
aacaaacaaaaagctatggagatcctgtttgctaagattcaagctgaatttgaaaaggag
gacaaaggtaatagcagacctcagcgtagaagacggacaatcagtcgtcaaattattgca
ggtcttcaagatggagaggagctgtatgaagcagtgggggatgacccagcgtatctggag
gctcaattgagtgaacagcagttggagactctacgtagctacagatgttctctgatggaa
aagaagcaggctgacctgcaggatcgcttcagacaagctttagaaaatgcagaggagagc
gaaggtagctgtcccaagagagacgtcactcctgtgtggaggctctgcctcgcggacctc
atggaccaacctggcagggtctaccagctgaacttttggcgaccttcctcggatcttcag
tctttactgaaggaaggcagtcgatacaaagtctataatgtcaccacttcagacagaaag
aaacatgttggtaacacaactgttcagctgactgggacaaagaaaacacagtttcaggac
ctcccggtctctcaggaatggttatcaacacattttcaaccgagagtctctacccatttt
gtggatcttcaaaacacagaactgcagccgcagtgtggagaagttgatctcacaggatat
gtcatcagcatcgtagatggacagggtttctctccggcattttatctgactgatggggaa
atgaactttatcaaagtgcgctgtttcagcagctttgctcagtctggcttggaagatttg
gtaaagccaaatgttctgttggctctgagcaacctgcagctgagaggtcagtccacatct
cccacgcctgttgtgtacgctggagatctgaccgtcttttccacaaaccccaaagaggtt
catctgcagaaatctctctgccaactcagaaaactggcccagggtcaggatagcttcttt
acaattgctgaggagaagctttcacatttagggaaatctgatggcacgagttccttctct
tctccagctctgcaaacacgaaacacagctttcacaacagtcagaagactggacacatac
acaagtgtgacatctcagcagccagtccgaagccttggatccttcacacctgtcagcagg
aagcctcctgcagcaaactgctccacagagaaagaccccaacagcctgaagaagaggaga
gctctggactatctgtctcgtatcccgtcccccccacctctttccccgtttggcccagtg
gcttctccatgtgtaaatacgacattcaacccccctcggaggtctgggactgggacacct
agcactttaaaaactgtacagactccagctcagacacctgttgaaactccagtggaggat
gagtgggtgaatgacgaggaactagctatgattgacactcaggacttacatgttgctgat
ctactgtag
DBGET
integrated database retrieval system
