KEGG   Gambusia affinis (western mosquitofish): 122820302
Entry
122820302         CDS       T07758                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
gaf  Gambusia affinis (western mosquitofish)
Pathway
gaf00562  Inositol phosphate metabolism
gaf01100  Metabolic pathways
gaf04020  Calcium signaling pathway
gaf04070  Phosphatidylinositol signaling system
gaf04081  Hormone signaling
gaf04082  Neuroactive ligand signaling
gaf04261  Adrenergic signaling in cardiomyocytes
gaf04270  Vascular smooth muscle contraction
gaf04310  Wnt signaling pathway
gaf04371  Apelin signaling pathway
gaf04540  Gap junction
gaf04621  NOD-like receptor signaling pathway
gaf04912  GnRH signaling pathway
gaf04916  Melanogenesis
Module
gaf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:gaf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122820302 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    122820302 (plcb3)
   04371 Apelin signaling pathway
    122820302 (plcb3)
   04020 Calcium signaling pathway
    122820302 (plcb3)
   04070 Phosphatidylinositol signaling system
    122820302 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    122820302 (plcb3)
   04081 Hormone signaling
    122820302 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    122820302 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    122820302 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122820302 (plcb3)
   04916 Melanogenesis
    122820302 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122820302 (plcb3)
   04270 Vascular smooth muscle contraction
    122820302 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gaf04131]
    122820302 (plcb3)
Enzymes [BR:gaf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     122820302 (plcb3)
Membrane trafficking [BR:gaf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    122820302 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    122820302 (plcb3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like EF-hand_PLCG2
Other DBs
NCBI-GeneID: 122820302
NCBI-ProteinID: XP_043953552
LinkDB
Position
LG18:17898456..17960726
AA seq 1205 aa
MAGAKPGVHALQLKPVIVHEELKKGSKFIRWEEDCASSIPVLGTLKVDENGFYLTWIAGG
QQETEIIDMWTICDTRKGKYAKPPKDPKLREKLSYEKERLESNLLTIVYGVDMVNVSFMY
LLGLDEKTTQIWTDELFDLATNILSRNSSRIRHLYKAYTKLKLHGNSDGRIPMKHFLKLF
SDKKRVETAMEQCNLNNNKSESVKTEDLTWEVFLKFLDNLCIRPELQSIFEECGARRKPF
ISLDQFLEFLNDKQRDSRLNEVLYPPLKRDQVRQVMEKFESNLSQLERDQLSLQGFSRFL
NSEENNSLPLENLDLFDDMTHPLAHYFINSSHNTYLTVGQLTGASSVEMYRQVLLTGCRC
IELDCWKGKPPDEEPYITHGFTMTTEIPFKEVIEAIAESAFKASPYPVILSFENHVDSPK
QQAKMAEYCRTIFGDALLIDPLDKYPLEQNVPLPSPQELMGKILIKNKKKPQLEKTTVRR
KDPVPIQPSPSCDSPLTDTEGQKILSNGDQKQAEKTAKDPGHRGEGESEEEEENDPLPEG
KKAASEEGTALNEVSATEEMSNLVNYIQPVKFKGFDNALRRRRHYEMSSFVETKAIEILK
TFPFECLTYNKKQMSRIYPKGTRVDSSNYMPQLFWNIGCQMVALNFQTLDLPMQLNMGVF
EYNGHSGYLLKPEIMTRGDKQFDPFTEEIVDGIVANTVTIRIISGQFLTDKKVGVYVEVD
LFGLPRDTKRRCKTKTSNGNSMDPVWEDEQFIFYKVILPSLASLRISAFEENGKFIGHRI
LPVSSLKRGYRYINLRTEFNQPLLMASLLVYTEAKDYVPNQHMDYIEALTNPIKHINQLD
AREMQLAALLEEAESEDDSSELQDIPESLPSPELPLPSSPFEETPEWLPPPVQSPTEEDF
IVAIVTDVPSLSLEELKQNKSLTKLRKKHIKDFNELRKKNQKKIQSESQKKRTTIEKNFK
RSIKKGDSQEKIGDLEKQKAQLWENNMQELLELRQGFYMQEKQMQLQHLEEEHEKLKLTV
TEYQELHTKKLTDLCSKEKKEIQKVLEKKRIQSLVEAKKKDPDLKLSDFNKKHINDCVEI
FRKLEKLQIVRKEKFLLKHLEMTQQMESLLTQLESQLNEKLEEEYRQLPRDISQHLPSDL
QNKGACMGSPLSAESNHTSGTPSNCSMPWFPTSLDKSMDNNQGSLHDSTSSSTTPAPSES
ELSFN
NT seq 3618 nt   +upstreamnt  +downstreamnt
atggccggggccaagccgggagtccacgcgttgcagctgaaacccgtgatcgtccacgaa
gagctgaagaaggggagcaagttcatcagatgggaagaggattgtgccagctctataccc
gtcctggggaccctgaaagtcgacgaaaatgggttttacctgacatggatagcagggggc
caacaggagaccgaaatcattgacatgtggacaatctgtgacacaaggaaaggaaagtac
gccaagccaccgaaggatcctaagttacgggagaagctgtcctatgaaaaagagcggttg
gaatcaaatctgctgaccatcgtctatggagtagacatggtgaacgtctcgttcatgtat
ttgttgggtttggatgagaaaaccacacagatttggacagatgagctcttcgacctggcg
accaacatactgtccaggaattcatcgaggatcaggcacctttacaaagcgtacactaaa
ctaaagctccatgggaattcggatgggaggatccctatgaagcactttttgaagttgttt
tctgataagaagagggtggagactgcaatggagcagtgtaacctaaacaacaacaagtct
gaaagtgtaaaaaccgaggatttgacatgggaggtttttctaaagttcctcgataacttg
tgcatccgacccgaactgcagagcatctttgaggaatgcggtgctcggaggaaaccgttc
atctctctcgaccagttcctggagttcctcaacgacaagcagcgggactccaggctgaac
gaggtgctgtacccccccctgaaacgagaccaggtccgacaggtcatggagaaatttgag
agcaacctcagccagctggagagagaccagctcagtttgcagggtttcagtcgattcctc
aacagtgaggaaaacaatagcttacctctagaaaaccttgacctctttgatgacatgacc
catccgctggctcactacttcataaactcctctcacaacacctacctcacagtgggtcag
ctgacgggcgcgtcatcggtggagatgtacaggcaggtgctgctcactggctgccgttgc
attgagctggactgctggaagggcaaaccaccagacgaggagccgtacatcacccacggc
ttcaccatgaccactgagatcccatttaaggaggtgattgaagcgatagcagagagcgct
ttcaaggcttccccttaccccgtcatcctgtcttttgaaaaccacgtcgactcacctaag
cagcaggccaagatggcggagtactgcaggacgatttttggagacgccctgctcattgat
ccactggataaatatccgctggaacaaaatgtccctcttccttcaccacaagaactgatg
ggaaagatcctgatcaaaaacaagaagaagcctcagcttgagaagacaaccgtacggcgc
aaagatcccgtcccgatccagccgtcgccctcctgtgattcccccctcacagacacagag
ggacagaagatcctgtccaacggcgaccaaaagcaggctgagaagacggccaaagacccg
gggcaccgaggagaaggagaaagtgaggaggaagaggagaatgatccgctgccagaggga
aaaaaggctgccagtgaagagggtacagccctaaacgaagtgtccgccaccgaggagatg
tccaatctcgtcaactacatccagcctgttaaattcaagggctttgacaatgcgttgagg
agaagaaggcactatgagatgtcttcatttgtggaaaccaaagccatagaaatcctgaaa
accttcccctttgagtgtcttacgtataataagaagcagatgagccggatctaccccaaa
ggaacgagggtagatagctccaactacatgcctcagctcttctggaacatcggatgccag
atggtggcactgaacttccagactcttgacctccctatgcagctgaacatgggcgtattt
gagtataatggccacagcggctacctgctgaagccagagatcatgacgaggggggacaaa
cagtttgacccctttacagaagaaatagtggatgggattgttgccaatactgtcacaatt
cggataatctcaggtcagttcctgacagataaaaaggttggcgtatatgtggaggtcgac
ctgtttggacttccacgagatacaaagaggaggtgcaaaaccaagacctccaatgggaac
tccatggaccccgtgtgggaagatgagcagtttatcttctacaaggtgattctcccctca
ctggcctctctgaggatatctgcatttgaagaaaacggcaagttcatcggacaccgaatt
ctcccagtttcttccctcaaacgtggttaccgctacatcaacctgaggacagagtttaac
cagccactattaatggcctctctgctggtttacactgaagctaaggactatgtccctaat
caacacatggactacatcgaggccctgaccaaccccattaagcacatcaaccagttggac
gcaagagaaatgcagctcgctgctctcttggaggaagctgagtctgaagacgactccagt
gagttgcaggatattccagaatcactcccttcccctgagctgccgcttcccagcagccct
tttgaagagacgcctgaatggctacctccaccagtgcaaagtcccacggaggaggatttc
atagtagccatagtcacagatgtcccaagtctgtctctggaggaactgaagcagaataag
agtctcaccaagctgagaaagaaacatattaaagacttcaatgagctgcgaaagaaaaac
caaaagaagattcagtctgagagtcaaaagaagcggaccaccattgagaaaaacttcaag
cgtagcatcaagaaaggtgattcccaggagaagattggagacctggagaagcagaaggcc
cagctctgggagaataacatgcaggagctgctggaactccgacagggtttttatatgcag
gaaaaacagatgcaactgcagcacctggaagaggagcatgagaagctaaaactgacggtg
actgaatatcaagaacttcacaccaagaagctcacagacctttgcagcaaggagaagaag
gagatccaaaaggtcctggaaaagaagcgaatacagagccttgtagaagcaaagaagaaa
gatcctgacttgaaattatcagatttcaacaagaaacacataaacgattgtgtggagatt
tttcgcaagcttgagaagttgcaaatcgtgagaaaagagaagttcttactgaagcatctg
gaaatgacgcagcagatggaaagtctgcttacacagcttgagtcgcagctgaatgaaaaa
ctggaggaggagtaccgtcagctgccgagagacatcagtcagcaccttccttcggacctg
cagaacaaaggcgcctgtatgggctccccgttatccgccgagtccaatcacacctctggc
acgccctccaactgctccatgccctggttccccacatcgttggacaagagcatggacaac
aatcagggctcgctgcacgactccacgtcctcctccactactcctgccccgtcggagtca
gaactttctttcaactag

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