Gambusia affinis (western mosquitofish): 122821542
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Entry
122821542 CDS
T07758
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
gaf
Gambusia affinis (western mosquitofish)
Pathway
gaf04217
Necroptosis
gaf04620
Toll-like receptor signaling pathway
gaf04621
NOD-like receptor signaling pathway
gaf05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
gaf00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
122821542 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122821542 (tyk2)
04621 NOD-like receptor signaling pathway
122821542 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
122821542 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gaf01001
]
122821542 (tyk2)
Enzymes [BR:
gaf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122821542 (tyk2)
Protein kinases [BR:
gaf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
122821542 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
Kinase-like
RIO1
SH2
Kdo
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
122821542
NCBI-ProteinID:
XP_043955513
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All DBs
Position
LG19:complement(19368959..19378755)
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AA seq
1155 aa
AA seq
DB search
MPRKSGFFKPGKTPDPNEAPQSHGIHIYLFWTKGGERYLSHTSGDTTAEDLCISAAEAVG
ITPLCHVLFALYNPKTKYWYSPNHVFSPDENSSELVHYCMRFYFRNWHGLNEKEPTVSRH
TLKSGIDNNTGSPLLDITSLEYLFAQAKHEFVNNVEEPKSDEETNRFKNESLGMAVLHLS
HLAMQKGLNLQEVAGKIGFQNCIPRTFAENISRDNFLTKIRIRRVFTEFVQTFQQHTVDK
GQLGAHEIMYKYISTLENLVPSFGTETFSVTRLHLTEDGDESISYSINESNGDSKKDFAA
PFTHEIMVSGTKGIQWRMLKTQKAEENSYHRGNYLNQRTPKRSTSNPPDKWTFFCDFREI
IHISITEANVCINTQKSHCMEVQMNSSQEARAFISLLDGYYRLTADAHHYLCHEVAPPRV
VLSEANMLHGPMHEDFVLHKLKKEAGEEGAFLVRWSALDYHRIILAVLNRNENGSKPSHK
QFRIQHKGSVFCMEGWDKEFSSVKELTDNLKTYVLKSGSDNFTVRKCCLPRQAEISNLLV
KRQGIDQHNYSDCLPLNLTELRFHQIKDKEIKQENHLGRGTRTNIYSGQLMLRETDNGFN
NNFSQTKGIRVVLKILEESHKDIALAFFETASLMSQVSHSHLVFVHGVSVKGSENILVEE
YLECGPLDVFLRREQNSITAQWKFVVSLQLARALNYLETKRLVHGNVCAKNVLVARGGLE
PGTSPFIKLSDPGIALNVLSREERLDRIPWIAPECIDSGAPIESTADQWSFGVTLLEIFN
NANLPMSSCTLPEKERFYQTKGRLANPSSEELARFISMCLTYEPNERPTFQTILRELTKL
IQMNPDISPVDTLPPMDPSVFQKRYLRKMRDLGEGHFGKVTLYQYDPSSDGTGEFVAVKS
LKQENGNAPQSWMKEIEILKSLYHSNIVKYKGLCTEAGRQEVQLIMEYVPLGSLREYLPK
NKTSSTQCLMFAQQICQGMDYLHSKRYVHRDLAARNVLVENKNVVKIGDFGLTKYIPEGE
IYYRVREDGDSPVYWYAIECLKELKFSFASDVWSFGVTLYEILTRCDHRQSPPAKFIEMS
EDKEEHMNVVKLIKLLERNQRLPCPRDCPHEVKLLMDQCWDANPDNRPTFSNLIERFESA
RKMLDWTFSPMSQIC
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
atgcctagaaaatcaggttttttcaagccgggaaagaccccagatccaaatgaggcccct
cagtctcatggcatccacatctaccttttctggactaaaggtggggagaggtatctgtct
cataccagtggagataccacagcagaggacctgtgcatctcagctgcagaagctgtaggg
ataacaccactgtgccatgtcttattcgcgttgtacaacccaaaaacaaaatactggtac
agtccgaaccatgttttcagtccagatgagaactccagtgaattggttcactactgtatg
aggttttactttcgcaattggcacggactcaatgaaaaggagccaactgtgtcccgccat
accctcaaatctgggatagataacaatacaggttcccctcttcttgacattacatctttg
gagtatctgtttgcccaggccaagcatgaatttgtgaataacgtggaagagccaaagtct
gatgaggaaaccaatcgtttcaaaaatgagagcttgggcatggctgtactccacctgtca
cacctcgcaatgcaaaaggggttgaacttacaggaagttgctggaaaaattggcttccag
aactgcattccaagaacatttgcggagaacatttccagagacaactttctgactaaaatc
aggatccgccgtgtgtttacggaatttgtgcagactttccagcagcacactgtagataag
gggcagctgggagcccatgaaatcatgtataagtacatctccacccttgaaaacttggtt
ccaagtttcggaacagagactttctctgtaactcgcctgcatctgacggaggacggggat
gaaagcatctcttactccatcaacgaaagcaatggtgattcaaagaaggacttcgcagcg
ccgttcacccatgaaattatggtgtctggcactaaggggattcagtggagaatgttgaaa
actcaaaaggcagaggaaaactcttaccataggggcaactatttgaatcagagaacacca
aaacggtccacgtcaaatcctcctgataaatggaccttcttctgcgatttccgcgaaata
attcacatctccattacagaagctaatgtgtgcattaacactcagaaaagtcactgcatg
gaggtgcagatgaactccagccaggaggcccgtgcctttatctccctgctagatggatac
tatcggctgactgcagacgcccaccactatctttgtcatgaagtggctccccccagggtg
gtgttgagtgaagcaaatatgttgcacggacctatgcatgaggactttgtgttacacaag
ctgaaaaaggaggcaggagaggagggagccttcctcgtccgctggagtgccctcgactat
catcgcatcatccttgctgtgctaaacagaaatgaaaatggttcaaaaccaagccacaag
cagtttcgcatccagcacaagggctcggtgttctgcatggaaggctgggataaagagttc
tccagtgtgaaggagctcacagataacctcaaaacctatgtgctcaagtccgggtcagac
aactttactgtcaggaaatgctgtttaccgagacaagcagaaatatccaatctgctggtg
aagaggcaaggcattgaccaacacaactattctgactgcttgcccctgaacctgacagag
cttcgctttcaccagatcaaagacaaagagataaaacaggaaaatcatttgggccgcggc
acaagaactaatatttactcaggacagttaatgttgcgagaaacagacaatgggtttaac
aacaacttctcccaaaccaaaggcatcagagtggttctcaaaatcttagaggaaagccat
aaagatattgctctagccttttttgaaacagcaagcctcatgagccaggtatctcacagt
cacctggtgtttgtgcacggtgtgtctgtcaaaggatccgaaaacatcctggtggaggaa
tacctggagtgcggcccacttgatgtctttctccgcagagaacaaaattccatcacagct
cagtggaaattcgttgtatccctgcagcttgcaagggctctcaattatcttgagacaaaa
cgacttgttcacggaaatgtttgtgccaagaatgttctggttgctcggggaggtttggaa
cctggaacttctcctttcatcaagctgagtgatcctggaattgcgctgaatgtcctctca
cgagaagaacgtttggatcggataccctggatcgctccagaatgcattgacagtggcgct
cctattgagagtactgcagatcagtggagttttggcgtcacactgcttgaaatcttcaac
aatgctaatcttccgatgagcagctgcacattgcctgagaaagagcgtttttaccagaca
aagggccgtctggcaaacccatcctccgaggaactggccagattcattagcatgtgtttg
acatatgaaccaaatgagaggcctacgtttcaaaccatcctcagagaactcacaaaactc
attcagatgaatcctgatatatccccggttgacactctcccacccatggaccccagcgtg
tttcaaaagcgctacctgaggaagatgagagacttaggggagggacattttggaaaagtc
actctgtaccagtatgatccgtccagcgatgggacaggagagtttgtggcagtaaaatcg
ttgaagcaagagaacggaaatgcacctcagagctggatgaaggaaattgaaatcctgaag
tctctctatcattccaacattgtgaagtacaagggcttatgcactgaagccggacgacaa
gaggtccagctcataatggaatatgttcctctggggagtctgcgagagtatcttcctaaa
aataaaaccagttcaacccagtgcctcatgtttgctcagcagatctgtcaggggatggac
tacttgcactcaaagcgctatgtgcatcgagatcttgctgctcgaaatgttttggtggaa
aataaaaatgttgtaaagattggagacttcggcctaacaaagtacattcctgaaggagaa
atctactatcgggttcgtgaggacggagacagtcctgtctactggtatgccatcgagtgc
ttgaaagagctcaaattctcatttgcctctgacgtctggtcgtttggagttacactgtat
gagatcctcacgcgctgtgaccatcgccagagtcctccagctaagttcattgaaatgtca
gaagataaggaagaacacatgaatgtggtgaaactcataaagctgctggagagaaatcaa
agattgccttgtcccagggattgcccacatgaggtgaagttgttgatggatcagtgttgg
gatgcaaatcctgataatcggcctacgttcagtaacctcatcgaaaggttcgagtcagca
cgaaaaatgcttgactggacgttcagtcccatgtctcagatttgctga
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