Gambusia affinis (western mosquitofish): 122823551
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Entry
122823551 CDS
T07758
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
gaf
Gambusia affinis (western mosquitofish)
Pathway
gaf04010
MAPK signaling pathway
gaf04012
ErbB signaling pathway
gaf04020
Calcium signaling pathway
gaf04510
Focal adhesion
gaf04518
Integrin signaling
gaf04520
Adherens junction
gaf04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
gaf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122823551 (erbb2)
04012 ErbB signaling pathway
122823551 (erbb2)
04020 Calcium signaling pathway
122823551 (erbb2)
09133 Signaling molecules and interaction
04518 Integrin signaling
122823551 (erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122823551 (erbb2)
04520 Adherens junction
122823551 (erbb2)
04530 Tight junction
122823551 (erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gaf01001
]
122823551 (erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gaf04147
]
122823551 (erbb2)
04090 CD molecules [BR:
gaf04090
]
122823551 (erbb2)
Enzymes [BR:
gaf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122823551 (erbb2)
Protein kinases [BR:
gaf01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
122823551 (erbb2)
Exosome [BR:
gaf04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
122823551 (erbb2)
CD molecules [BR:
gaf04090
]
Proteins
122823551 (erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Tcell_CD4_C
Haspin_kinase
DUF5849
Kinase-like
Motif
Other DBs
NCBI-GeneID:
122823551
NCBI-ProteinID:
XP_043959234
LinkDB
All DBs
Position
LG20:20757488..20788340
Genome browser
AA seq
1288 aa
AA seq
DB search
MEAARSLLLVGAVLLGATGAWSREVCLGTDMKLALPSSLENHYETLRLLYTGCQVVHGNL
EITHLSGNPDLSFLKEIVEVQGYVLIAHVSVSLVPLDNLRIIRGSHFYNSNYSLAVLDNQ
GLKTLRLRSLKEILLGGVSILGNPQLCFPDPENIIWRDTLDEQNTKPHRLQARAPNCPKC
HPTCGKSCWGETEQDCQTLTRINCASGCQRCKGPLPNDCCHTQCAAGCTGPRDSDCLACR
HFNDSGMCKENCPPPNFYDPVTYQSKPNPNKKLSFGATCVKTCPYNYLAMEVACTLNCPR
SNKEVIIKQPDGTETQKCEKCEADCVKDCHSFGTDNLGVVDNHSVTVVTSANVGQFTKCS
KIFGSLAFRAQSFARDPVTNSSGLTLQQLKGFRKLEEIAGYLYIDAWPQEWSNLSVFENL
KVIRGRMLYMGVFSLAVQNLHIQSLGLRSLRSVSGGLVLLYNNSELCYTDSLPWGSILHP
TEGPQRIVRLNQEPRACEVEGHVCHPLCKGGCWGPGPAQCVSCKTFQRGTVCVEQCDVYQ
GAVPEYIDGSLCKTCHDECRPLNASASCHGPGADDCTECLHYQDEKICVERCPSGVKEDQ
QTVWKYSNETRHCLPCNTNCTLSCTMMDERGCPIDTRTGSTTTVAAAVGGVLLFLILLGL
LVFYLKRQKKLKRKETMRRYLQEQELVEPLTPSGASPNQAQMRILKETELKKLRPLGAGA
FGTVYKGVWAPEGEHITIPVAIKVLRENTSPKGNKDILDEAFVMASVTSPYVCRLLGICL
TSAVQLVTQLMPYGCLLDYVRENKDRIGSQYLLNWCVQIAKGMNYLEDIRLVHRDLAARN
VLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSDVWSYGV
TVWELMTFGSKPYDTIAAREIPDLLEGGERLPQPPICTIDVYMIMVKCWMIDPDSRPKFK
DLVQDLSAMARDPSRYLVIQNDEQMSSCSPVDSQFYRMLLEEGENLGDMMDAEEYLVPQP
NLFPRTRGDQAQAQANGPTRHQSYRSKDLDAEPLTAGGPQSMYSSLSTLGRGQCPTLPVG
ASMSNGLWPQLARTTSAGGQSDSVFLDATPDGHFLSPSSPGRYCKDPTYPRGSQCDLETD
ETDGFHHPNHLHHSLPRRSHNHSQRPAMPEYVNQEMLDPRPAIPERPTTLPRKGSRVDRR
LPNGLGSGHSVENPGYLIPVSSACPAFDNPYYLDLGGKANAAPSGAAVDGGAAQESNGNI
TRHVNGFVTPTAENPEYLGLADTWTGHT
NT seq
3867 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgagaagtttgttgctggtcggggccgttttgctgggagcgacgggcgct
tggagccgggaagtttgcctgggaacggacatgaagctagctcttccctccagcctggaa
aatcactacgagaccctgaggctgctctacaccggctgccaggtcgtccacggcaacctg
gagatcacacacctgagcgggaacccggacctctccttcctgaaggaaatcgtagaggtg
cagggttatgtactcattgctcatgtctcggtgagcctggtgcctttggacaaccttcgg
atcataagaggaagccatttttacaactccaactattcgctggctgtgctggacaatcag
gggctgaagacgctgcggcttcgtagcctcaaagagatcctgttgggcggagtgtctatt
ttggggaacccccagttgtgcttcccggacccggaaaacatcatatggagagacactctg
gacgaacagaacaccaaaccgcaccgcctgcaggcccgagctcccaactgtccaaaatgt
catcctacgtgtgggaagagctgctggggggaaaccgagcaggactgtcaaacactgacc
agaataaactgtgcgtctggctgtcagcgatgcaaaggtcctcttcctaacgactgctgt
cacacgcagtgtgcggccgggtgcaccggacccagagactcggactgtttggcatgccgt
cacttcaacgacagcgggatgtgcaaagagaattgccccccacccaacttctacgacccc
gtcacctaccagagcaaacccaaccccaacaagaagttgagctttggagccacctgcgtc
aagacgtgtccctataactacctggccatggaagtggcctgcactttgaactgtccccga
tccaacaaggaagtcatcatcaagcagccggacggcaccgagacgcagaaatgcgaaaag
tgtgaagctgactgcgtcaaagattgccacagtttcggtacggacaacctgggcgtcgtg
gacaaccacagcgttaccgtggtaacgtctgctaatgtgggtcagttcaccaagtgttcc
aagatcttcggaagcctggctttccgcgctcagagcttcgccagggaccctgtgaccaac
tcatccggtctgactctgcagcagctgaagggcttcaggaagctggaggagattgcaggt
tatttgtacatcgacgcctggccacaggaatggagcaacctttctgtgtttgagaacctc
aaagtgatcagaggcaggatgctctacatgggcgtgttttcactggccgtccagaatctg
cacatccagtctctggggctgcgttcgctgcgcagcgtcagcggaggcctggtgttgttg
tacaacaactctgagctgtgctacaccgactctctgccctgggggtcaatcctccatccc
accgaggggccgcagcgcatcgtcagactcaaccaggaaccccgagcgtgcgaggtggag
ggacatgtttgccatccactgtgtaaggggggctgttggggcccggggcccgcccagtgc
gtgtcttgcaagacgttccagcgaggcaccgtgtgtgtggagcagtgtgacgtctatcag
ggagctgttcctgaatacattgatgggtctttgtgcaaaacctgtcatgatgagtgtcga
cctctgaacgcctctgcatcctgccacggcccaggtgcagacgactgcaccgagtgtctg
cactatcaggatgaaaagatctgtgtggaacgttgtcccagcggagtgaaggaagatcaa
caaactgtgtggaaatacagcaatgaaacgcgacactgtctgccctgcaacactaactgc
acactgtcctgcaccatgatggatgagcgaggctgccccattgacaccaggactggctcg
acaacaaccgtcgctgctgcagtcggtggagtcttgctcttcctcatcttgctgggtctg
ctggtcttttatctgaagagacagaagaaactgaagaggaaggagaccatgaggaggtac
ctgcaggaacaggagctggtggagccgttgacgccgagcggcgcgtctccaaaccaggct
cagatgcgaatcctgaaagagacagagttgaaaaagctcaggcctctgggtgcaggggcc
tttgggactgtctataagggggtgtgggctccagaaggagaacacataacgataccggtg
gccattaaagtcttgagggagaacacttcaccgaaaggcaacaaagacattcttgatgag
gcgtttgtgatggcgtcggtcaccagcccttacgtgtgtcgcctgctggggatttgcctg
acgtccgccgtgcagctggtcactcagctcatgccgtacggctgcctcctcgactacgtc
agggagaacaaggatcgcatcggttcccagtacctcctgaactggtgtgtccagattgcc
aaggggatgaattatctggaggacattcggttggtccacagagatctggccgcccgcaac
gttctggtgaagaacccaaaccacgtgaagatcacggacttcggcctggcccgtctgctg
gacatagacgagacagagtatcacgctgatggaggaaaggtgccgattaaatggatggct
ttggagtctattctgcacaggaagttcacccatcagagtgacgtctggagctacggggtg
actgtttgggagctgatgacgttcggctccaagccgtacgataccattgcggcgagggag
atcccagacctgctggagggaggagagcggcttcctcagcccccgatctgcacaatagac
gtctacatgatcatggtcaaatgctggatgattgatccagacagcaggcccaagttcaaa
gatctggttcaggacctgagcgccatggcgagagatccgtctcgctacttagtcattcag
aacgacgagcagatgagttcctgcagcccggtggacagccagttctaccggatgcttctg
gaggaaggagagaacctgggggacatgatggacgccgaggagtacctggtaccgcagccc
aacctgttccccagaaccaggggcgaccaggcccaggcccaggccaacgggccgacccgc
caccagtcctaccggagcaaagatctggatgctgagcctttgaccgctggtggacctcag
agcatgtactcgtctctgagtactttgggccgcggccagtgccccaccctgccagtggga
gcgagcatgtccaacggcctgtggccccagttggctcgtaccacttcagcaggaggccag
tctgactccgtcttcttggatgcgactccagacggacatttcttatcgccgtccagccct
ggacgctactgcaaagaccccacctaccccagagggagccagtgtgacctggaaaccgac
gagacggacggctttcatcatcctaatcaccttcatcactccctgcccaggaggagccac
aaccacagccagagaccagccatgccagagtacgtgaaccaggagatgctggatcccaga
ccggcgatccctgagcgacccactacgctcccacgtaaaggctccagagtggaccgacgg
ctccccaacggcctcgggtccggccacagcgttgagaacccggggtacctaatccccgtc
agctccgcctgccccgccttcgacaacccgtactacctggacctcgggggcaaagccaac
gccgctcccagcggagcggcggttgacggcggcgcggcccaggagagcaacggaaacatc
accaggcacgtcaacgggttcgtcacacccactgcggaaaacccagagtatctcggactt
gcagacacctggactggtcacacttga
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