Gambusia affinis (western mosquitofish): 122824868 Help Entry 122824868         CDS       T07758                                  Symbol mdn1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism gaf  Gambusia affinis (western mosquitofish) Pathway gaf03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:gaf00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     122824868 (mdn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:gaf03009]     122824868 (mdn1) Ribosome biogenesis [BR:gaf03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     122824868 (mdn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_7 AAA_16 AAA_22 nSTAND3 TsaE AAA_6 ABC_tran Sigma54_activat AAA_14 Mg_chelatase Dynein_heavy bpMoxR Sigma54_activ_2 AAA_25 MDN1_4th DUF815 AAA_28 AAA_33 AAA_8 PduV-EutP VWA_2 TniB Motif Other DBs NCBI-GeneID:  122824868 NCBI-ProteinID:  XP_043961638 LinkDB All DBs Position LG22:complement(22276848..22336641) Genome browser AA seq 5503 aa AA seqDB search MENLEVSLSSLAIISRHVEKSHNQISQYLSKQIWSQQDRQSILECLAQLLLEKDYTLLIA RHVRPLVLDLLERNAERVKAGGKINHDFHERLCVALSRLLSISPDAHAFAVRYFSSAPPV FQRLFFTSEQSSAVQYGPRRMKLRDLMAATLRFLQSDCAKFRMLWDWSPCVSQLLTSDVM VRGSTAQCLALVCHMTDNQKAIFLRKVLSSDEILHMKMKAVEESRQVEVEKALVLTNQRS VKWHQEFAQKFTRGQVVSEDLSQNVVAVCGVILPKMVPWQQAEQVKPSRLVLVESTCQNL RRLALAIASQKPVLLEGPIGCGKTALVEHMAAVTGHTNTADILKVQLGDQTDSKMLLGMY RCTDVPGKFVWQPGTLTQAVSKGLWILLEDIDHAPLDVISVLLPLMENKKLMIPGREDCI EVAPGFQFFATRRMYCSGGNWHKPQNSHAALLNKFWTKLQMRNMSYAELKKVLIHRYPML AVVSDRLLDIYCQLTGERHSELDTSTEGQQDKPEDRSTSLEGRALSMRDLLKWCERISVN FDSASPATAQRVFLEALDCFTAMLSRPASRLRMAEIIGSKLNISNEKAQYFCQLYQPGVS LTELQAAVGRVTLPRQQADTVQLAVVSSSKTFAPTQPSAVLLEQLAVCVAKGEPVLLVGE TGTGKTSTVQHLASVTGHKLCVVNMNQQSDTADLLGGYKPVDHRQILLPLREAFEDLFSQ TYSRKQNLTFLGHVQTCFREKRWQDLLRLMDHVCKSALAKELQEKPEDSSLLQQWEALAS KLSQTQLQIRACDTAMVFAFVEGTLAKAVKKGHWILLDEINLAAAETLECLSGLLEGSTG SLVLLDRGDTEHLVRHQDFRLFACMNPATDVGKRNLPLGLRNRFTELYVHELENEGDLRI LVSDYLKCLNPPKSVISGIISFYLAARREASSHLVDGTGHRPHYSLRTLCRALNYAAANP CLSVQRSLYEGFCLSFLTQLDRSSHPLVQKLVCQHILAGNTKCLKQLIPAPPGRTCVQIE GYWVPQGELEPALDPSYILTASVKLNLRDLSRVVSAGIHPVLIQGETSVGKTSLIRWLAT ATGNQCVRINNHEHTDIQEYIGCYSSDDRGKLVFKEGVLLDAMRKGYWVILDELNLAPTD VLEALNRLLDDNRELFVAEMQEVIRAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELH FDELPSAELETILHQRCSLPPSYCTKLVKVMLDLQSLRRGSSVFAGKHGFITLRDLFRWA ERYRLEEQGEATQDWLQHLADDGYMLLAGRVRKQEEEAVILDTLQKHFKRTVNPDSLFSQ KQLISQFSPAVGSVAAVPEEFRHVVWTQSLRRMAVLLGRALRFGESVLLVGDTGCGKTTI CQLYAALAGQKFFSVNCHMHMETSDFLGGLRPVRYTQQTVGEDVRLFEWNHGPLVLALKE GGVFLLDEISLADDSVLERLNSVLETEKSLVLAEKGSGDDDDVELIRAAAGFRLVATMNP GGDFGKKELSPALRNRFTEIWCPQSSSRSDLVQIIQHNLRSGLSLNGIDVAEVMLDFVEW LGQQDFGRRCVLSIRDILSWVNFINAVCERDEASCMTMRASEEQEEDEEEAKWDLRLNAV TACVHAACLVYIDGLGSGTTASCADGALAARRMSLAFLQRRLSRTTRLDEEMLEALRVYD PCLPRDPQWGEDFFGINPFYIAIGSEAESRSLSDYALTAGTAAMNAQRLLRALKLQRPVL LEGSPGVGKTSLVAALAKASGNQLVRINLSEQTDITDLFGTDLPVEGGKGGEFAWRDGPL LAALKAGHWVVLDELNLASQSVLEGLNACFDHRAEIYIPELGLSFQVQQEKTKIFGCQNP FTQGGGRKGLPKSFLNRFTQVFVDQLTYKDMEFIGNSIFPAIDKEIIAKMVEFNNRLVQE VCVERLWGQKGSPWEFNLRDIFRWCQLMLTDQSPGFFNPGQHVALVYADRMRTEADKAKV LLVFREVFGEDYEPYCGSKHFHITPLSVQVGFSVLCRSGGAPVAVDPPLSITHQCLKPLE SLMKCVDMGWMTIVVGPTASGKTSLVRLLALLTGHRLQVMAMNNSMDTTELLGGFEQVDI IRPWQQVLETVDYMVAMVIRRGLMSLDNGTQDTEFLLQTWGVFCQWLKENGLQRPAGAVT CEALNKLEVIILLLQKLNTKLKVFTDMSKLQMDFTLLKERLAQLEDGWTNGGFEWLDGML VQALQAGDWLLMDNVNFCSASVLDRLNALLEPNGSLTINERGVIDGKTPRITPHPNFRLF LTMDPVHGELSRAMRNRGVEVYIPGELEGLCWDTLDLKTLLHSAGVTGNCVCDLLIQIHQ DIRSAIWDSSASSVAALLHAASLLSCQLQRGADLRSALQHTCTEVYAFCQRSAANQKQAQ QVIEQHLVVMDKGAWGDGLLCAGVWPDSFPSALLSTEDSCFSSVLRDGQVLLFCLNSLSL QGKRNRPLRLRDLQQALQSSGVHEDCVFSGGVLDLEDGDALRLIPTAVRLVTERASHGDW ILRSHWLSSLGKSSKYLPEPALVHVEAGNRALKAVFSSTLAVKGKTLAELLQPHSKDEYR ILIDMRWNKQYLDILTNKCNFEDEERYMEFLEALNAVANRTVLMMDREERAVSCSCTISM APPTSALRVATAFSKGSLDISQLPHPVLMHLRAFFDQWDAYVLQAVQNGQPHISDHVMFE ILQLLRWRDHFWDVCIMLPADSQGVSVLSLHWQWLQKHLILRLPQLLMGDTAATLEGQQD LQAVSAAIQNLLSTPVSVAAALKGMQRSLGKALPYKLEAVAECASRLRLLSTALDVNTLQ LDEALSWGGQQLLRVQAAGLWLDIKESLLEASGLVLSANNQLDPHKSGILEKLLLSVERL QSHMTSRGLSGVSSMSDGEAEQGEVHMGRAGLLQLRTQTQLWPLMEGLSVLNQLLLSADL LHLALSPCDHVAEDDLRRRLSRHLRFCLQSTPMNVGQLQSLWFLLSSDGLQEKLPLVWCD LLSEALAALWSCSVTSDPTRWLRWNPVDPETQKDLTLRPGAENMGPALLNKAVWSRCILG VLSRGEVQAEAPLSCGVSLGEWEERVQQLEVVSSVLWENLTFPATAHFRVTDLRLQGAVL RRQLQSMADLLPPHLQEGYMESCESLVQDAAPVTAAQEIQTLLKNFLPPQLLPEGLMAAC TACLQQFVQVKGQGGDSLAQCGVFWVNMGLLQIRVWTPQTIFDPAVKRSYKLSYAQQELA LLQDEWKARSASSELKSGEELKESSTTDGFQHPRIRYLWIRMQQVKDQIAELSRKQAFRP QQAQYGRLFRELQHYLSSVGHMSAVEELLSRLLKALQDPSYFRSGSAIRALLREEAGWQN SQQRFCQKLLDDYSLFPDLVGPVRTGLLQLRHGMRLVASQLAISLTPVPGLSKLVSCLVS FPSVSPSLPSDLDRAQFLCSRTCIDVVHSLEKLLPQQEAGSVAPQPSALLLNALLYVYCH SLSTGELSEEACSLFRHICQAVVNEWDNQEKRKQEQEQLEASLYRSRSRLHGSGLTQDQQ DETDFRRYFPQFSKDFADILSQPSLEGPADTEPEHEADSAAASLSGPAINTLVQVHQCVC LGYAQSLWYQSAPLTNHSKEHIKALISSHQIASPVMTHFYHLIDSELDLQLAGWGLLLSA LFQNTVSGSGGSDELALSSEGPYDFYQQPNMREARLCLPVLEQLSETVKMRLEEWPEHPA LVQLNVVMDRIRSFSLACPLAKFLNGLEILLGKAQEWENNASRAVSLRNELEPVTQLIIQ WRKLELNCWSSSLDNTLKCHMEKSTKHWFSLYQLVERYLQEQREEVDTAGEQTDSLSLSS VSSTLEAFMEGSTLGEFHTRLRMLLSFHCHLLLVPDLPGQESLSRLLWNLHQYYSQFSES VQAKILQLRQPIEKELKDFVKISKWNDVSYWSIKQSVAKTQRTLFKFVKRFEDALSGPSL AALVEQRSSSSWDPEPARSGDSPIQRVHQVLKSAMPGQGRELQNEDLEEGAGSSSLQARL PVLFRKMKKMSIQLLKRTSLPELAEDLDCFTGEIISNLRDLQSLSIDTAAAKEKQQTEVK HILQQKQRALSDLFKMLSEIGLSYRKGLIWNRTADPESILCMHPLEMTTALSAVKTQSQP ERVLFTELLGAWEGCQKYFYRSWARRTTLRTALQHASKELGVGNIERCRGFSSHLFKLLL RQRQRLAQLTQHWVSLRKLTASLQSVQTHLQSHREDGGCYLPPQDSLQDWFRRGRGLAAQ SATLLQQLSWLLQCCPEEPQQREQTGASSRRHTLMCPSPLAVQQQPPGCLLRRGDPGWTQ LQQQVAAMLKDSQSVKEQLASSGSILCSWSSFTTCCSAMEQLGGVAAQMSSIESLFSPLT GEGGANTQPTMTQSLNYVRGQVETAITEFTSWRSQVLSPGAEPIGQQSAFWSFFSAELET NISALLHAVQRLVKRRTTEDEGQTQEEPKTDGAEEEKEQPVEDLLKPGHLTRLLEAKLEA EVEALSVGSVSVAMTKLLGCVRRHRDSCPPSQLQEVNQACRALVRFLPLLGVYSDLARYY LSESLAVHRSTGKLLSVLSSIFTQLAQKGFCLPQELMPGGDADGATEFHDYEGGGIGDGD GNKDVSDKIENEDQVEDSFQEGAEKEEQQNLENIKSEDNGIEMSEDFDGRVHDGDENEGG EDKESDEEEEEELDKKMGDLGEGQTDTLDERMWGDDEEEDEEEGSEKEEESGQGMDQGES ELVAKEDNLDTADSNRDKKSQDQDEEQREEKEKIHEQGDEREFDENEVDPYHGQQEQRPE PEAMDLPDDLNLDQEEEAGGDEDGDDENPLDIDDKAMEVELKEEEQRDGEEEESEETEME NQRDDEQNQEPKSEEEDEKGHEKQEEEEEAADEDKEEKEGKENREAQEEKDKAAGDDRGE IPKQEDEAESEDDEQPSSAERKEHGADGQTGEQNIQSDSAVELAGAAAETDQAKEEHGSG AADASQSEGHQSKLTARMASQKQTQSQTQSFKRKPGQADNERSTGDYSERVNKRLRTVES SQEHSESRQADSQHDSDLYEHIRPAETAYDSQTYDVANAEQQKAAGPLKDQDEDKNDDVA METEDQEEQLLSADVEELKPEQLETSKFSQKGVESRETEQQRQDEEDERLKKQQPPGEEE RSTRSTESTIHTDPALLLLSEQKTERDPEELRREMELQLEAWRQLAPGTQEEEAAAASMW LQYQALTSALSQQLCEQLRLILEPTQAAKLRGDYRTGKRLNMRKVIPYIASQFRKDKIWL RRTKPSKREYQICLAVDDSSSMVDNHSKQLAFESLSVIINALTLLEVGQVSVCSFGEQMQ LLHPFQQQFNDESGARILRLCQFQQKKTRIAQFLETSTKMFLSARQQIPGSLSSETAQLL LIVSDGRGLFLEGKERVVAAVQAARTANIFVIFVVLDNPNTRDSILDIKVPIFKGPGELP EIRSYMDEFPFPFYVILRDVNALPETLSDALRQWFELITAADQ NT seq 16512 nt NT seq  +upstreamnt  +downstreamnt atggaaaatctagaagtgagtctgtcatctctggccatcatatccagacatgtggagaag agtcacaaccagatcagccagtatctgtctaagcagatctggagccagcaggacagacag agcattctggagtgtttggctcagctcctcttggagaaggattacactctgctgattgcg cgtcatgtccggccgctggtcctggacctcctggagcgcaacgcagagagggtcaaagct ggtggcaaaatcaaccatgacttccatgagcgtctgtgcgtggccctcagtagactcctc agcatcagtcctgatgcgcatgcgtttgctgtgaggtacttcagcagtgccccgccagtg ttccagaggctgtttttcactagcgaacagtcatctgcggtccagtatggccctaggagg atgaagctccgtgacctcatggctgccaccctgcgcttcctccaaagtgactgtgctaag tttcggatgctgtgggactggagtccctgtgtttcacagctactcaccagtgatgtcatg gttcgagggtccacggctcagtgtttagctcttgtctgccacatgactgataatcagaaa gccatcttcctgaggaaagtgctgtcgagtgatgaaattctgcacatgaaaatgaaagct gtggaggagagtcggcaggtggaggtggagaaagctctggtgttaactaatcagaggtca gtaaagtggcaccaggagttcgcccagaagttcaccagaggtcaggtggtatcagaggac ttgtcccagaacgttgtagcagtctgtggagtcattctgcccaagatggttccgtggcag caggctgagcaggtgaagccaagccgcctggtgctggtggagtcaacgtgccagaacctg agaaggctggctctggccattgcgtcccaaaagcctgtgctcctggagggtccgattggc tgtgggaaaactgctctggtggagcacatggcagccgtcaccggacataccaacactgca gacattctcaaggtccagcttggggatcaaactgacagcaagatgctgctgggaatgtac cgatgcactgatgtaccggggaagtttgtgtggcagccaggaaccctaacccaggccgtt tctaaaggcctctggatccttctggaagatattgatcatgcacctctggacgtgatttct gtcctcttgcctttgatggagaataaaaagttgatgattccaggacgagaggattgcatc gaggttgctcctggattccagttctttgcaaccagaaggatgtactgcagtggtggcaac tggcacaagcctcagaactcccatgcagcactgctgaacaagttctggaccaagctgcag atgcgtaacatgtcctacgcagaactcaagaaggtgctcatccacaggtaccccatgttg gcagtggtgtcagaccgtctgctggacatctactgccagctgaccggtgagagacactct gaattggacaccagcacagagggacagcaggacaaacctgaggatagaagcacatcgctg gagggcagagctctgtcaatgagggacctgctgaaatggtgcgagcgaatcagtgtgaac tttgacagcgcctccccagccacagcacagcgagtcttcttagaggctcttgactgcttc acagccatgctttcccgccctgccagcagactgcgcatggctgagatcattggaagcaag ctgaacatttccaatgagaaggctcagtacttctgccagctgtatcagcccggcgtgtcg ctgacggagctgcaggctgcagtgggcagagtcactctacctcggcagcaggccgacacc gtgcagctggccgttgtaagcagcagtaagacatttgctccaacccaaccctcggctgtt ctgctggaacagctggctgtttgtgtggccaagggggagcccgtcctcctggtgggagag acgggaacagggaagacctccacggtgcagcacctggcctcagtcactgggcacaagctg tgtgtggtgaacatgaaccagcagagtgatacagccgatcttcttggaggatacaagcca gtagaccacaggcagatcctgctgcccctgcgggaggcttttgaggacctgttctcccag acgtactccaggaagcagaacctgaccttcctgggccatgtacagacctgctttcgggaa aagcgctggcaggatctgcttcgactcatggaccatgtttgcaagtctgctctggctaag gagctgcaagaaaagccagaagattcctctctgctgcagcagtgggaggctctggcatcc aagctgagccagacccagctgcagatccgagcctgtgatacagccatggtgtttgctttt gtggaggggacgttggctaaggcagtgaagaagggccactggatcctgctagatgagatc aacctggcagcagcagagacgttggaatgtctgagtgggctactggagggcagtactggc tctctagtcttactggatcgtggagacactgagcacctggttcgccaccaagacttccgc ctctttgcatgcatgaacccagctactgatgtcgggaaaaggaaccttcctctgggtctc agaaacagatttactgagctgtatgtacatgagctggagaacgagggagacctgaggatc cttgtgtcagactacctcaagtgcttgaacccacccaagagtgtcatcagtggtatcata agtttctatctggcagctcggcgggaggcctcttcccatctggtagacgggactggtcac aggcctcactacagcctgcgcacgttgtgccgggctctgaactacgcagcagctaacccc tgcctcagcgttcagcgttctctgtacgagggcttctgtttgagtttcctcacccagctg gacaggagctcccatcctctggtccagaagctggtgtgtcaacacatcctagcagggaac accaaatgtctgaaacagctgatcccagctccaccaggccggacctgtgtgcagatagag ggctactgggttccacagggagaactggagccagctctggatcctagttacatcctcact gcttcagtaaagctcaacctgcgcgatctgtccagagtggtatctgcagggattcaccca gtgctgatccagggggagacgtctgttgggaagaccagcctgatccgctggctggcaact gccactgggaaccagtgtgtgagaatcaacaaccatgagcacaccgacatccaggagtat attggctgctactcctcagatgacaggggcaagctggtgttcaaagagggtgtcctgctt gatgccatgaggaaaggctactgggtgatcctggatgagctgaacctggcccccaccgac gtcctggaggctctcaacaggctgctggatgacaacagggaactgtttgtggctgaaatg caggaagtcatcagggctcatcccagattcatgctgtttgcaacacagaaccccccaggg ctctacggaggcagaaaggttctgtcccgggcattcaggaaccgctttgtggagctgcac ttcgatgagctgcccagtgcagagctagagacaatcctgcaccagaggtgtagcttacct ccatcctactgcacaaagctggtcaaggtcatgctggaccttcagtcattgcgcagagga tcttctgtgtttgcggggaaacatggcttcatcactctgagagacctgttccgctgggcg gagcgctaccggctggaggagcagggggaggccactcaggactggctgcagcatctagca gatgatggctacatgctgctggctggacgggtcaggaagcaggaggaggaggccgtcatc ctggacaccctgcagaagcacttcaaacggacagtgaaccctgacagcctgttctcccag aaacagctcatcagtcagttcagtcctgcggtgggcagtgttgcagcggtaccagaggag ttccgtcatgtggtgtggacccagagcctgaggaggatggcggtgctgctggggcgagcg ctgcgctttggggagtcggttctgctggtgggagacacaggatgtgggaaaaccaccatc tgccagctgtatgcagctctggctggacagaagttcttctctgtcaactgtcacatgcac atggagacgtcggacttcctgggaggcctacggcccgttagatacacccagcagactgtt ggtgaggacgtcaggctgtttgagtggaaccatggaccattagtgctggccttgaaggag ggcggagtcttcctcttggatgagatttcactcgcagacgattctgtgctggaaaggctc aacagtgtcctggagacggagaagagtctggtgctggcagagaagggcagcggagatgac gatgacgtggagctgatcagagcagctgcaggcttccgcttggtggccaccatgaaccct ggaggagactttggcaagaaggagctgtctcctgccctgaggaaccgcttcactgagatt tggtgtcctcagagcagcagccgcagcgacctggtccagatcatccaacacaacctgcgc tctggactctcattaaatggcatagacgttgcagaagtgatgctggacttcgtggagtgg ctgggccagcaggattttggccggcgctgcgtcctgagcatcagagacatcctgtcctgg gtgaacttcatcaatgctgtgtgtgagagggatgaggccagctgcatgaccatgagagca tctgaggaacaggaggaagacgaggaggaggcaaagtgggatctcagactgaatgctgtc acagcttgtgtccatgctgcctgcttggtttacatagatggccttggttcaggaactaca gcgtcctgtgcagatggtgccctggctgcacgccggatgtctctggctttcctgcagcgg aggctgagtaggacgacccggcttgatgaggagatgctggaggccctgagggtctatgac ccctgcctgccacgggaccctcagtggggagaggacttctttggcatcaaccccttctac atcgccataggatctgaagctgagagccgcagcctgtctgactacgccctcacagcaggc actgcggccatgaacgcccagaggcttttgcgggctctgaagctgcagaggcccgtgctg ctggagggctcccccggagtgggaaagaccagtctggtggcggcgctggccaaggcctcc gggaaccagctggtcagaatcaacctgtctgagcaaacagacatcaccgacctgttcggg acagatcttcctgtggagggagggaagggaggagagtttgcgtggcgagacggccccctg ctggctgctctgaaggctggccactgggttgttctggatgaattgaacctggcgtcccag tcggtgttggagggactcaacgcctgctttgatcacagggcagagatatacattcctgag ctgggcttgagcttccaggtccagcaggagaagaccaagatcttcggctgccagaacccg ttcacacagggcggtggacgcaaaggactgcccaaatccttcctcaacaggttcactcag gtctttgtggaccagctcacctacaaagacatggagttcattggaaattctattttcccc gccattgataaggaaatcatcgcaaaaatggttgagttcaataacaggcttgttcaggag gtctgtgtggagaggctgtgggggcagaaaggaagcccctgggagttcaacctgcgggac atattccgctggtgtcagctgatgctcactgaccagtcgccaggattttttaacccaggc cagcatgtggccttggtttatgctgacagaatgagaactgaggcagataaggcaaaggtc ctgctggtgttcagggaggtgtttggggaggattatgagccttactgtggctccaaacac ttccacatcactcctctcagcgttcaggtgggcttctctgtgctgtgtcgtagtgggggg gccccggtggctgtggaccccccactgtccatcacacaccagtgcctgaagcctttagag tctctgatgaagtgtgtggatatgggctggatgaccatagttgttggtccaacagccagt gggaagaccagcctggtgagactgctggccctgctgacggggcaccgcctccaggtgatg gccatgaacaactccatggacaccacggagctgctggggggattcgagcaggtggacatc atacgtccatggcagcaagtgctggagacagtcgactacatggtcgcaatggtgataagg cgtggactgatgtctcttgacaatggcacccaggacacagagtttctgctgcagacatgg ggtgtgttctgccagtggttgaaggagaatggcctacaaagaccagcaggagcagtgacc tgtgaggcactcaacaagttggaggtcatcatccttctgctgcagaaactcaacaccaag ctcaaagtgttcaccgacatgtccaagctgcagatggacttcactctgctgaaggagcgt ctggcccagctggaggacggctggaccaacggcggcttcgaatggctggacgggatgctg gtccaagccctgcaggccggggactggctgctcatggacaatgtcaacttctgcagtgct tctgtcctggatcgcctcaatgctcttttggagcccaacggatccctcaccatcaatgag cgcggtgtaatcgatgggaagaccccaaggatcacccctcaccccaacttcaggctgttc ctcaccatggacccggtgcatggggagctctccagagccatgagaaacagaggggtggag gtctacatcccaggggaacttgaggggttgtgctgggacactttggacctaaagaccctg ctccactctgccggtgtgacagggaactgtgtgtgtgacttgctcattcaaatccatcaa gacatcagaagtgccatctgggactcctcagcctcttcggttgcggctcttctccatgct gcctctctgttgtcctgccagctgcagcgaggtgcagaccttcgcagcgccctgcagcac acctgtactgaggtctatgccttctgtcagcgctctgctgccaaccagaagcaagcccag caagtgattgagcagcacctggttgtcatggataagggtgcctggggagacgggctgctg tgtgccggggtgtggccggacagcttcccctcagctcttctctctacggaagattcctgc ttctcctctgtcctcagggacgggcaggtcctcctgttctgcctcaactccctcagcctg caggggaaacgaaaccgtccactgagactgagagacctgcagcaggccttgcagagcagt ggagtccatgaagactgtgtgttttctggaggagtactggatctggaggatggtgatgct ctcaggctcatccccactgcagtgaggctggtgacagagagagcatcgcatggagactgg atcctccgcagccactggctctccagcctggggaagagctccaaatatctgccagagccg gcgctggtccatgtggaggcaggaaaccgagctctgaaggcggtgttcagcagcaccctg gctgtaaaggggaaaacgctggcagagctgctgcagccgcacagcaaagatgaatacagg attctgattgacatgcgctggaacaagcaatacctggatattctaactaacaagtgcaac tttgaggatgaggagagatacatggagttcctggaggctctgaatgcagtggctaacagg actgttctgatgatggaccgggaggagagagctgtcagctgctcctgcaccatcagcatg gctccacccacttccgctcttagagtcgccacagccttcagcaaaggaagcttagacatc agccagctgccccaccccgtgctcatgcacctgcgagcgttctttgaccagtgggacgcc tacgtcctgcaggccgtgcagaatggacagccgcacatctctgaccacgtcatgtttgag atcctgcagctgctccggtggcgcgaccacttctgggacgtgtgcatcatgcttccagcg gactcccagggcgtctcggtgctgtcgctgcactggcagtggctgcagaagcacctcatc ctgcgcctgcctcagctgctgatgggagacacagcagccactctggagggtcagcaggac ttacaggctgtttcagcagccatccagaaccttttgtccactccagtgtcggtggccgct gcactcaaaggcatgcagaggtctctggggaaagctctgccttacaagctggaggcggtg gcagagtgtgcgtcccggctgcggctgctcagcacggctctggatgtgaacacgctgcag ctggacgaggctctgagctggggagggcagcagctgctccgggtgcaggcagccggactc tggctcgacatcaaggaaagcctcctggaggcatcaggtctggttctgtctgctaacaac cagctggacccacacaagtctgggatcctggagaagctgctgctgagcgtggagcggctg caaagtcacatgacctccagagggctgtcaggggtcagctccatgtctgatggagaggca gagcagggcgaggtccacatgggccgagctgggctgctgcagctccgaacccagacccag ctctggcctttgatggaaggcctgtctgtcctcaatcagctgcttctcagtgcagatctg ctgcacctggctctgtctccatgtgaccatgttgctgaggatgacctgcgccggcggctg tccagacaccttcgcttctgcctgcagtctacgccgatgaacgtggggcagctgcagagc ctgtggttcctgctgagcagcgacgggctgcaggagaagctgcctctggtgtggtgtgat ttgctctctgaggccctggctgctctctggagctgcagcgtgacctctgaccccacccgc tggctcagatggaacccagtggatccagaaacccagaaggatctgacactgcgccccgga gcagagaacatgggcccagcgttgctgaataaagcagtgtggtcccggtgcattctggga gtcctgagcaggggagaggtgcaggcggaggcccccctgtcctgtggggtcagcctgggg gagtgggaggagagagtccagcagctggaggtcgtctcttctgtcctgtgggaaaacctg acctttccagccacagcccatttcagggtaacggacctgaggctgcagggggcggtgctg cggcgtcagctccagagcatggccgacctgctgcccccccaccttcaggagggctacatg gagagttgtgagagcctggtgcaggacgctgcgccggtcactgctgcccaggagatccag acgctcctcaagaacttcctgcctccccagctgctgcctgaaggcctgatggcggcctgc acagcctgtctgcagcagtttgtccaggtcaaaggtcagggtggagactcccttgcccag tgtggtgtgttctgggtcaacatgggcctgctgcagatccgagtctggacaccgcagacc atctttgacccggcggtgaagaggagctacaaactgagctacgctcagcaggagctggct ctgctgcaagatgagtggaaagcacgcagcgcatcatctgagctgaagagtggagaggag ttgaaggagagcagcaccactgatggcttccaacatcccaggatcagatacttgtggatc cgcatgcaacaggtgaaggatcagatagcggagctgtccaggaagcaggccttccggcca cagcaggcccagtatggccgcctgttccgggagctgcagcactacctgagcagcgtgggc cacatgtcggctgtggaggagctgctgtctcggctcctgaaggccctacaggacccgtcc tacttcaggtccggttcagccatccgggccctgctcagagaggaggctggctggcagaac tctcagcagcgcttctgccagaagctcctggacgactactctctgtttcccgacctggtg ggcccagtccggaccggcctactccagctgcgtcacggcatgaggctggtggcctcccag ctggccatctctctgactcctgtccctggcctgtccaagctggtgtcctgcttggtgtcc ttcccctccgtgtcccccagcctcccatcagacctggaccgggcccagttcctgtgttcc aggacctgtatagatgttgtgcatagcctggagaagcttctgccccagcaagaggcaggt agcgtggcccctcagccatctgctctgctgctgaatgctctgctgtatgtctactgccac agcttgtccacaggagagctcagtgaggaggcatgcagcctcttcagacacatctgccag gctgtggtgaatgagtgggacaaccaggagaagaggaagcaggagcaggagcagctggag gcttctctgtaccgcagccgcagccgtctgcatggctcaggcctgacccaggaccagcag gacgagacagacttcaggcgctacttccctcagttcagcaaggactttgcagatattttg tcccagcccagcctggaaggcccggctgacacagaaccagaacatgaggctgattctgct gcagcctctctgtctggacctgccatcaacacactggtccaggtgcatcagtgtgtgtgt ctgggttacgcccaatcactgtggtaccagagcgcaccactaaccaatcacagtaaagaa catatcaaagccctgatctcttcccatcagattgcttcccctgtgatgactcacttctat catctgattgattcggagctggacctgcagctggccggctggggcctgctgctctctgcc ctcttccagaacactgtgtcgggctccgggggttctgatgagctggccctctcctcagag gggccctatgacttctaccagcagcctaacatgagagaggcgcgcctctgcctgcctgtc ctggaacaactgagtgagacggtgaagatgaggttggaggaatggccggagcaccctgct ctggtccagctgaacgtggtcatggacaggatcaggtcgttcagcttggcctgccctctg gccaagttcctcaatggtctggagattctgcttggcaaggcgcaggagtgggagaataac gccagccgtgccgtgtccctgcgaaatgaactggaaccagtcacccagctgatcatccag tggcgcaaactggagctgaactgctggtcaagcagcctggacaacaccttgaagtgccac atggagaaatccaccaaacactggttctccctctaccagctggtggagcgttacctccag gaacagagagaggaggtggatacagcaggagagcagacagacagcctgtccctgtcctct gtgtcctccactctggaagccttcatggagggctccaccctgggcgagttccacacccgt ctgagaatgctactcagcttccactgccacctcctgctggtgcctgatctcccaggtcaa gagtctttgtcccgacttctgtggaaccttcatcagtactacagccagttctctgagtcc gtccaggccaagatacttcagctcaggcagcccattgagaaggagctcaaagactttgtc aagatttccaagtggaatgacgtcagctactggtccatcaagcagtcagtggcgaagaca cagcgcactctcttcaagtttgtgaagaggtttgaggatgctctgagtggacccagtcta gcagcgctggtggaacaaagaagcagttccagctgggacccagagcccgccaggtcaggg gactctcccatccagagggttcatcaggtgctgaagagcgccatgcctggccagggcagg gaacttcagaatgaggacctggaggaaggcgctggatcatcttccttacaggcccgtttg cctgttttgttccggaagatgaagaagatgagcatccagctgctgaagagaacatcccta cctgaattggctgaagatctggactgttttactggtgagataatcagcaacctacgagac ctgcagagcctcagcatagacacagcagcagccaaagaaaagcagcagacggaggtcaag cacatccttcagcagaagcagagagctctgtctgacctgttcaagatgctctctgaaata ggcctctcgtaccgcaaagggctgatatggaacagaaccgctgacccagaaagcattctc tgcatgcacccgctagagatgaccactgcgctctctgctgtgaagacccagagccagcct gagcgtgtgctgtttacagagttactgggagcctgggaaggatgccagaaatacttctac cgttcatgggccaggaggacaaccctgcggaccgctctccagcacgcatcaaaggagctt ggtgttgggaacatagagcgctgcagaggtttctcctcccacctgttcaagctgttgctc agacagaggcagcggctggcccagctgacccaacactgggtctcactcaggaagctaact gccagcctccagagcgtgcagacccacctccagagccacagagaggatgggggctgttac ctgcccccccaggactctctgcaggactggttcagaagaggccggggcctggcagctcag agtgccacgcttctgcaacaactgtcctggctgctccagtgttgtcctgaagaaccccag cagagggagcagacgggcgccagcagcaggcgccacaccctgatgtgcccttcccccctg gcagtgcagcagcagccccccggctgcctgctgaggaggggagaccccggctggacccag ctgcagcagcaggtcgctgccatgctgaaggacagtcagagtgtgaaggagcaactggcc tcctctgggtccatcctctgctcctggagcagctttaccacctgctgttcagccatggag cagctagggggtgtggcagcccagatgagcagcatagagagcttgttttccccgttaacc ggggagggtggggccaacacccagcccaccatgacacagagtctgaactacgtccgagga caggtggagacagccatcactgagtttaccagctggaggagtcaggtcctgtccccgggg gccgagcccatcggtcagcagtctgctttctggagcttcttttctgctgagctggagacc aacatcagcgccctgctgcatgctgtccagagactggtgaagaggaggacgactgaggat gaaggacagacacaggaagagccaaagacagacggagctgaggaggagaaggagcagcct gtggaggacctgctgaagcctggtcacctgacccggctcttggaggcgaagcttgaagct gaggtggaggctctgtctgttggtagtgtgagcgttgccatgacgaagctgctgggctgt gtgaggagacacagagactcctgtcccccttcacagctgcaggaggtgaaccaggcctgc agggcgctggttcggttcctgcccctgctgggggtctattcagacctggcccgctactac ctctctgagtccctcgcagtccacagaagcacaggcaagctgctgtctgtgctgtccagc atcttcacccagctggcccagaaggggttctgtctgcctcaggagctgatgcctggaggc gacgcggacggagccacagagttccatgactacgagggcggaggcatcggagacggagac ggcaacaaggacgtcagcgacaagatcgagaatgaagaccaggtggaggattccttccag gagggagcagagaaggaggagcagcagaatttggagaacatcaagtcagaggacaatggc atcgaaatgtctgaagactttgatggacgagttcatgatggagatgagaatgaaggaggt gaagacaaggagtctgatgaagaggaggaagaggagctggacaaaaagatgggagacctg ggagaaggtcagacagacacgttggatgagagaatgtggggggatgatgaagaggaggat gaagaggaaggcagtgagaaggaagaggagtctggacagggcatggaccagggcgaatct gagctggtggctaaagaggacaacctggacacagccgactccaacagggacaagaagagt caggaccaggatgaagagcagcgcgaggagaaggagaagatccacgagcaaggagacgag agagagtttgatgagaacgaagtggacccgtatcatggtcagcaggagcagagaccagaa ccagaggccatggaccttcctgatgacctcaacctggaccaggaggaagaggctggagga gatgaggatggtgatgatgaaaaccctctagacatcgatgacaaggccatggaggtggag ctgaaagaggaagaacagcgagatggagaggaagaggagtcagaagaaactgagatggag aaccagagagacgatgaacagaaccaggaacccaaatctgaggaagaggatgagaaagga catgagaaacaggaagaggaggaagaggcagctgatgaagataaagaagaaaaggagggg aaggagaatagagaagcacaggaagaaaaagataaggctgctggagatgacagaggagaa atacccaagcaggaggatgaagctgagagtgaggatgatgagcagcccagctctgctgag aggaaggagcatggtgcagacggtcagactggagagcagaacattcagagtgactctgct gtggagctggctggtgccgctgcagagacagatcaggctaaagaggagcatggcagtggt gcagctgatgccagccaatcagaaggccaccagtccaaactgacggccaggatggcgtct cagaaacagactcagagccagactcagagctttaagaggaaaccgggccaagcggataac gagcgttcgacaggggattacagcgagcgcgtcaacaagcgcctgcgaacagtagagagc agccaggagcactctgagagcaggcaggcagacagccagcacgactcagacctgtatgaa cacatccgacctgcggagacggcctacgactcccagacctacgatgtcgccaatgcagag caacagaaggcagcaggacctctgaaggatcaggatgaagataaaaatgatgatgttgcc atggagacagaggaccaggaggaacagctcctgtctgctgatgtagaggagctgaagcca gagcaactggagacctccaagttctcccagaaaggtgtggagagcagagagactgagcag cagaggcaggatgaggaagatgagaggctgaagaagcaacagcctcctggagaggaagag cgatccaccaggagcactgaatccaccattcacacggatcctgctctcctgctgctgtct gagcagaagacagagcgagacccagaggagctgaggagggagatggagctgcagctggag gcctggcgtcagctggctccaggaacccaggaggaggaggctgcagcagcttccatgtgg cttcagtaccaggccctgacctctgccctctcccagcagctgtgtgagcagctgcgtctc atcctggagcccacgcaggctgccaagctccgtggggattaccgcacagggaagcggctg aacatgaggaaggtgatcccttacatcgccagtcagttcagaaaagacaagatctggctg aggaggaccaagcccagcaagagagagtaccagatctgtctagcagtggatgactcctcc agcatggtggacaatcactccaaacagttggcgttcgagtccctgtcagtgatcatcaat gctctcactctgctggaggtcggccaggtgtctgtgtgcagttttggggagcagatgcag ctgctgcatcccttccagcagcagtttaacgacgagtcgggggctcgcattctgcgcctt tgtcagttccaacagaagaagaccaggatagctcagtttctggaaacgtcaactaagatg tttctctcagcacgacagcaaattccaggatctctgagctcagagacggcccagctgctg ctcatcgtgtctgacggcaggggattgttcctggagggcaaggagcgtgtggtggcagct gtgcaggcagcacgcacagctaacatctttgtgatctttgtggttctggacaaccccaac acccgggactccatcctggacatcaaggtgcccatcttcaaagggccaggagagctgcca gagatccgctcctacatggacgagttccctttccccttctatgtcatcctgcgggatgtc aacgccctgccggagacgctgagcgacgcgctcaggcagtggtttgagctcatcacagct gctgaccaatag

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