KEGG   Gambusia affinis (western mosquitofish): 122841182
Entry
122841182         CDS       T07758                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
gaf  Gambusia affinis (western mosquitofish)
Pathway
gaf00562  Inositol phosphate metabolism
gaf01100  Metabolic pathways
gaf04012  ErbB signaling pathway
gaf04068  FoxO signaling pathway
gaf04070  Phosphatidylinositol signaling system
gaf04081  Hormone signaling
gaf04140  Autophagy - animal
gaf04150  mTOR signaling pathway
gaf04210  Apoptosis
gaf04218  Cellular senescence
gaf04370  VEGF signaling pathway
gaf04510  Focal adhesion
gaf04620  Toll-like receptor signaling pathway
gaf04625  C-type lectin receptor signaling pathway
gaf04810  Regulation of actin cytoskeleton
gaf04910  Insulin signaling pathway
gaf04914  Progesterone-mediated oocyte maturation
gaf05100  Bacterial invasion of epithelial cells
gaf05132  Salmonella infection
gaf05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:gaf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122841182
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    122841182
   04370 VEGF signaling pathway
    122841182
   04068 FoxO signaling pathway
    122841182
   04070 Phosphatidylinositol signaling system
    122841182
   04150 mTOR signaling pathway
    122841182
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    122841182
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122841182
  09143 Cell growth and death
   04210 Apoptosis
    122841182
   04218 Cellular senescence
    122841182
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122841182
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122841182
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122841182
   04625 C-type lectin receptor signaling pathway
    122841182
  09152 Endocrine system
   04910 Insulin signaling pathway
    122841182
   04914 Progesterone-mediated oocyte maturation
    122841182
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    122841182
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122841182
   05100 Bacterial invasion of epithelial cells
    122841182
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gaf04131]
    122841182
Enzymes [BR:gaf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     122841182
Membrane trafficking [BR:gaf04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    122841182
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 ABC1 C2 Retrotran_gag_4 Ribosomal_S15
Other DBs
NCBI-GeneID: 122841182
NCBI-ProteinID: XP_043990197
LinkDB
Position
LG12:3390033..3410970
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGCHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccccggccctcttccggagaactatgggggatgcacttgatgccccccagcatc
ctagtggactgcctgctgccaaacggcatgatcctcacgttggagtgcctccgggaggct
acgctcattacagtgaagcacgagctcttcaaggaagccaggaagtaccccctctaccat
ctgctgcaggaggagagctcctacatcttcgtcagcgtcacgcaggaggccgagcgcgag
gagttttacgacgagaccaggaggctgtgcgatctccggctcttccaggctttcctcaaa
gttatcgagccagtgggcaacagagaggagaaaatcctcaacagagaaataggcttcgcc
atcggaatgcccatatgcgagtttgatttggtgaaggactccgaagtacaggacttcaga
aggaacattttaaacgtttgcaaagaagccgtggacctcagagacagcaacggctgccac
agcagagcgttgtacgtctacccgcctaacgtggaatcgtccgcagagcttcccaggcac
atctacaataaactagataaaggccagattatcgtggtgatctgggtcatcgtttctccc
agcaacgacaagcagaagtacaccctgaagatcaaccacgactgcgtgcccgagcaggtg
atcgccgaagccatccggaagaagacgcgcagcatgctgctcactcaggagcagctgaag
atgtgcgtccaggagtaccaggggaagtacatcctcaaagtctgcggctgcgacgagtac
ttgctggagaaataccccctgagtcagtacaagtacatccgcagctgcatcatgctggga
aggatgcccaatctgatgctgatgtccaaggagagcctgtattcccagctgcccatggag
aacttcaccatgccgtcgtacgccaggcggatctccacggcgacgccctacatgaacggc
gagacggccaccaagtgtctctggacaatcaacgggacgctgaggatcaggatcctctgc
gccacatacgtcaatgtaaacatcagagacatagacaagatttacgtcaggactgggatc
taccatggtggggagcagctgtgtgacaatgtcaacactcagcgcgttccctgctctaat
cccaggtggaacgagtggctgacctacgacatgtacgtcacagaaattcccagagccgct
cgactctgcctctccatctgctccgtcaaaggaaggaagggagctaaagaggagcattgt
cccctggcctggggcaacatcaacctgtttgactacacacacacgctggtagcagggaag
atggctctcaacctgtggcctgtcccacacggcctggaggatctgctcaaccccatcggc
gtcacaggctccaaccccaacaaggaaaccccttgcttggagctggagttcgaccacttc
agctgcccagtcaagttccctgacatgagcatgatcgaggatcacgccaactggaacatt
tcccgggagctcggctttaattactcacaccccggcttgagcaacaggctggcacgggac
aaacccctgactgagagcgataatgaacagctgcgccaagtgtgtaaccgggaccctctg
tctgagatcactgagcaggagaaggactttctgtggagccacaggcattactgcatcaac
atcccagatatccttcccaagatcctcctggctgtgaagtggaactccagagacgaggtc
gcgcagatgtattgccttctcaaagactggcctgccattaagccagaacaagccatggag
ttgctggactgcaacttccccgaccccatgatccgagagttcgccgtgaagtgccttgag
aaatacctaaccgacgacaaactgtcgcagtacctcatccagctggtccaggttctgaag
tatgagcagtacctggacaaccctctcgcccgcttcctgctgaagaaggctctgaccaat
cagaggataggacacttcttcttctggcatttaaaatcagagatgcacaacaagacggtc
agccagcgcttcggcctcctgctggagtcgtactgccgggcgtgcggcatgtatctgaag
cacctgagccggcaggtggaggccatggagaagctcatcaatctcaccgacctgctcaag
caggagaaaaaagacgaggcgcagaaggtccaaatgaagtttctggtcgagcagatgaag
aggcctgactacatggatgcactacaaagctttacctctccgctcaacccggcacatcag
ctggggaacctccgcctggaggaatgtcggatgatgtcatcggcaaagcgacctctctgg
ctgaactgggaaaacccggacatgatgtccgaacttctcttccagaacaacgaaatcatc
ttcaaaaatggagacgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccagggccttgatctcaggatgctgccgtacggctgcctgtct
atcggcgactgcgtggggttgatcgaagtggtgaggaactctcacaccatcatgcagatc
cagtgcaaaggaggcctgaagggggcgctgcagttcaacagccacgctctgcaccagtgg
ctcaaggataagaacaagggggaaatgtacgaccaggccatcgacctcttcacccggtcg
tgcgccggctactgcgtggccaccttcatcctcggcatcggagacagacacaacagcaac
atcatggtgaaagacgacgggcagctgttccacatcgacttcggccatttcctcgaccac
aaaaagaagaagtttgggtacaagagggagcgggtcccgtttgttctcacgcaggacttc
ttgatcgtcatcagcaaagggacgcaagagtgtacaaaaaccagagagttcgaaaggttc
caggagatgtgctacaaggcgtacctggccatccggcagcacgccaacctcttcatcaac
ctgttctccatgatgctgggctcgggcatgccagagctgcagtcgttcgacgacatcgcc
tacatcaggaagaccctggccctggacaagtccgagcaggaggcgctcgactacttcatg
aagcagatgaacgacgcccatcacggcggctggaccaccaagatggactggatcttccac
accatccgccagcacgccatgaactga

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