KEGG   Gracilinanus agilis (agile gracile opossum): 123230857
Entry
123230857         CDS       T07702                                 
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01521  EGFR tyrosine kinase inhibitor resistance
gas01522  Endocrine resistance
gas01524  Platinum drug resistance
gas04010  MAPK signaling pathway
gas04012  ErbB signaling pathway
gas04014  Ras signaling pathway
gas04015  Rap1 signaling pathway
gas04022  cGMP-PKG signaling pathway
gas04024  cAMP signaling pathway
gas04062  Chemokine signaling pathway
gas04066  HIF-1 signaling pathway
gas04068  FoxO signaling pathway
gas04071  Sphingolipid signaling pathway
gas04072  Phospholipase D signaling pathway
gas04114  Oocyte meiosis
gas04140  Autophagy - animal
gas04148  Efferocytosis
gas04150  mTOR signaling pathway
gas04151  PI3K-Akt signaling pathway
gas04210  Apoptosis
gas04218  Cellular senescence
gas04261  Adrenergic signaling in cardiomyocytes
gas04270  Vascular smooth muscle contraction
gas04350  TGF-beta signaling pathway
gas04360  Axon guidance
gas04370  VEGF signaling pathway
gas04371  Apelin signaling pathway
gas04380  Osteoclast differentiation
gas04510  Focal adhesion
gas04517  IgSF CAM signaling
gas04520  Adherens junction
gas04540  Gap junction
gas04550  Signaling pathways regulating pluripotency of stem cells
gas04611  Platelet activation
gas04613  Neutrophil extracellular trap formation
gas04620  Toll-like receptor signaling pathway
gas04621  NOD-like receptor signaling pathway
gas04625  C-type lectin receptor signaling pathway
gas04650  Natural killer cell mediated cytotoxicity
gas04657  IL-17 signaling pathway
gas04658  Th1 and Th2 cell differentiation
gas04659  Th17 cell differentiation
gas04660  T cell receptor signaling pathway
gas04662  B cell receptor signaling pathway
gas04664  Fc epsilon RI signaling pathway
gas04666  Fc gamma R-mediated phagocytosis
gas04668  TNF signaling pathway
gas04713  Circadian entrainment
gas04720  Long-term potentiation
gas04722  Neurotrophin signaling pathway
gas04723  Retrograde endocannabinoid signaling
gas04724  Glutamatergic synapse
gas04725  Cholinergic synapse
gas04726  Serotonergic synapse
gas04730  Long-term depression
gas04810  Regulation of actin cytoskeleton
gas04910  Insulin signaling pathway
gas04912  GnRH signaling pathway
gas04914  Progesterone-mediated oocyte maturation
gas04915  Estrogen signaling pathway
gas04916  Melanogenesis
gas04917  Prolactin signaling pathway
gas04919  Thyroid hormone signaling pathway
gas04921  Oxytocin signaling pathway
gas04926  Relaxin signaling pathway
gas04928  Parathyroid hormone synthesis, secretion and action
gas04929  GnRH secretion
gas04930  Type II diabetes mellitus
gas04933  AGE-RAGE signaling pathway in diabetic complications
gas04934  Cushing syndrome
gas04935  Growth hormone synthesis, secretion and action
gas04960  Aldosterone-regulated sodium reabsorption
gas05010  Alzheimer disease
gas05020  Prion disease
gas05022  Pathways of neurodegeneration - multiple diseases
gas05034  Alcoholism
gas05132  Salmonella infection
gas05133  Pertussis
gas05135  Yersinia infection
gas05140  Leishmaniasis
gas05142  Chagas disease
gas05145  Toxoplasmosis
gas05152  Tuberculosis
gas05160  Hepatitis C
gas05161  Hepatitis B
gas05163  Human cytomegalovirus infection
gas05164  Influenza A
gas05165  Human papillomavirus infection
gas05166  Human T-cell leukemia virus 1 infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05170  Human immunodeficiency virus 1 infection
gas05171  Coronavirus disease - COVID-19
gas05200  Pathways in cancer
gas05203  Viral carcinogenesis
gas05205  Proteoglycans in cancer
gas05206  MicroRNAs in cancer
gas05207  Chemical carcinogenesis - receptor activation
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05210  Colorectal cancer
gas05211  Renal cell carcinoma
gas05212  Pancreatic cancer
gas05213  Endometrial cancer
gas05214  Glioma
gas05215  Prostate cancer
gas05216  Thyroid cancer
gas05218  Melanoma
gas05219  Bladder cancer
gas05220  Chronic myeloid leukemia
gas05221  Acute myeloid leukemia
gas05223  Non-small cell lung cancer
gas05224  Breast cancer
gas05225  Hepatocellular carcinoma
gas05226  Gastric cancer
gas05230  Central carbon metabolism in cancer
gas05231  Choline metabolism in cancer
gas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123230857 (MAPK3)
   04012 ErbB signaling pathway
    123230857 (MAPK3)
   04014 Ras signaling pathway
    123230857 (MAPK3)
   04015 Rap1 signaling pathway
    123230857 (MAPK3)
   04350 TGF-beta signaling pathway
    123230857 (MAPK3)
   04370 VEGF signaling pathway
    123230857 (MAPK3)
   04371 Apelin signaling pathway
    123230857 (MAPK3)
   04668 TNF signaling pathway
    123230857 (MAPK3)
   04066 HIF-1 signaling pathway
    123230857 (MAPK3)
   04068 FoxO signaling pathway
    123230857 (MAPK3)
   04072 Phospholipase D signaling pathway
    123230857 (MAPK3)
   04071 Sphingolipid signaling pathway
    123230857 (MAPK3)
   04024 cAMP signaling pathway
    123230857 (MAPK3)
   04022 cGMP-PKG signaling pathway
    123230857 (MAPK3)
   04151 PI3K-Akt signaling pathway
    123230857 (MAPK3)
   04150 mTOR signaling pathway
    123230857 (MAPK3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123230857 (MAPK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123230857 (MAPK3)
   04148 Efferocytosis
    123230857 (MAPK3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123230857 (MAPK3)
   04210 Apoptosis
    123230857 (MAPK3)
   04218 Cellular senescence
    123230857 (MAPK3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123230857 (MAPK3)
   04520 Adherens junction
    123230857 (MAPK3)
   04540 Gap junction
    123230857 (MAPK3)
   04550 Signaling pathways regulating pluripotency of stem cells
    123230857 (MAPK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123230857 (MAPK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123230857 (MAPK3)
   04613 Neutrophil extracellular trap formation
    123230857 (MAPK3)
   04620 Toll-like receptor signaling pathway
    123230857 (MAPK3)
   04621 NOD-like receptor signaling pathway
    123230857 (MAPK3)
   04625 C-type lectin receptor signaling pathway
    123230857 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    123230857 (MAPK3)
   04660 T cell receptor signaling pathway
    123230857 (MAPK3)
   04658 Th1 and Th2 cell differentiation
    123230857 (MAPK3)
   04659 Th17 cell differentiation
    123230857 (MAPK3)
   04657 IL-17 signaling pathway
    123230857 (MAPK3)
   04662 B cell receptor signaling pathway
    123230857 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    123230857 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    123230857 (MAPK3)
   04062 Chemokine signaling pathway
    123230857 (MAPK3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123230857 (MAPK3)
   04929 GnRH secretion
    123230857 (MAPK3)
   04912 GnRH signaling pathway
    123230857 (MAPK3)
   04915 Estrogen signaling pathway
    123230857 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    123230857 (MAPK3)
   04917 Prolactin signaling pathway
    123230857 (MAPK3)
   04921 Oxytocin signaling pathway
    123230857 (MAPK3)
   04926 Relaxin signaling pathway
    123230857 (MAPK3)
   04935 Growth hormone synthesis, secretion and action
    123230857 (MAPK3)
   04919 Thyroid hormone signaling pathway
    123230857 (MAPK3)
   04928 Parathyroid hormone synthesis, secretion and action
    123230857 (MAPK3)
   04916 Melanogenesis
    123230857 (MAPK3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123230857 (MAPK3)
   04270 Vascular smooth muscle contraction
    123230857 (MAPK3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123230857 (MAPK3)
  09156 Nervous system
   04724 Glutamatergic synapse
    123230857 (MAPK3)
   04725 Cholinergic synapse
    123230857 (MAPK3)
   04726 Serotonergic synapse
    123230857 (MAPK3)
   04720 Long-term potentiation
    123230857 (MAPK3)
   04730 Long-term depression
    123230857 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    123230857 (MAPK3)
   04722 Neurotrophin signaling pathway
    123230857 (MAPK3)
  09158 Development and regeneration
   04360 Axon guidance
    123230857 (MAPK3)
   04380 Osteoclast differentiation
    123230857 (MAPK3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123230857 (MAPK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123230857 (MAPK3)
   05206 MicroRNAs in cancer
    123230857 (MAPK3)
   05205 Proteoglycans in cancer
    123230857 (MAPK3)
   05207 Chemical carcinogenesis - receptor activation
    123230857 (MAPK3)
   05208 Chemical carcinogenesis - reactive oxygen species
    123230857 (MAPK3)
   05203 Viral carcinogenesis
    123230857 (MAPK3)
   05230 Central carbon metabolism in cancer
    123230857 (MAPK3)
   05231 Choline metabolism in cancer
    123230857 (MAPK3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123230857 (MAPK3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123230857 (MAPK3)
   05212 Pancreatic cancer
    123230857 (MAPK3)
   05225 Hepatocellular carcinoma
    123230857 (MAPK3)
   05226 Gastric cancer
    123230857 (MAPK3)
   05214 Glioma
    123230857 (MAPK3)
   05216 Thyroid cancer
    123230857 (MAPK3)
   05221 Acute myeloid leukemia
    123230857 (MAPK3)
   05220 Chronic myeloid leukemia
    123230857 (MAPK3)
   05218 Melanoma
    123230857 (MAPK3)
   05211 Renal cell carcinoma
    123230857 (MAPK3)
   05219 Bladder cancer
    123230857 (MAPK3)
   05215 Prostate cancer
    123230857 (MAPK3)
   05213 Endometrial cancer
    123230857 (MAPK3)
   05224 Breast cancer
    123230857 (MAPK3)
   05223 Non-small cell lung cancer
    123230857 (MAPK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123230857 (MAPK3)
   05170 Human immunodeficiency virus 1 infection
    123230857 (MAPK3)
   05161 Hepatitis B
    123230857 (MAPK3)
   05160 Hepatitis C
    123230857 (MAPK3)
   05171 Coronavirus disease - COVID-19
    123230857 (MAPK3)
   05164 Influenza A
    123230857 (MAPK3)
   05163 Human cytomegalovirus infection
    123230857 (MAPK3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123230857 (MAPK3)
   05165 Human papillomavirus infection
    123230857 (MAPK3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123230857 (MAPK3)
   05135 Yersinia infection
    123230857 (MAPK3)
   05133 Pertussis
    123230857 (MAPK3)
   05152 Tuberculosis
    123230857 (MAPK3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123230857 (MAPK3)
   05140 Leishmaniasis
    123230857 (MAPK3)
   05142 Chagas disease
    123230857 (MAPK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123230857 (MAPK3)
   05020 Prion disease
    123230857 (MAPK3)
   05022 Pathways of neurodegeneration - multiple diseases
    123230857 (MAPK3)
  09165 Substance dependence
   05034 Alcoholism
    123230857 (MAPK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123230857 (MAPK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123230857 (MAPK3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123230857 (MAPK3)
   04934 Cushing syndrome
    123230857 (MAPK3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123230857 (MAPK3)
   01524 Platinum drug resistance
    123230857 (MAPK3)
   01522 Endocrine resistance
    123230857 (MAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123230857 (MAPK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:gas03036]
    123230857 (MAPK3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gas04147]
    123230857 (MAPK3)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123230857 (MAPK3)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123230857 (MAPK3)
Chromosome and associated proteins [BR:gas03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     123230857 (MAPK3)
Exosome [BR:gas04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123230857 (MAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 123230857
NCBI-ProteinID: XP_044512973
LinkDB
Position
1:132997868..133005977
AA seq 380 aa
MAAVVAAEGGGGGEPRGVDGTGPGVPGKVEMVKGQPFDVGPRYTELQYIGEGAYGMVSSA
FDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRCHHENVIGIRDILRAPTLEAMRDVY
IVQDLMETDLYKLLKSQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCD
LKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML
SNRPIFPGKHYLDQLNHILGILGSPSQDDLNCIINMKARNYLQSLPSKPKVPWVKLFPKA
DSKALDLLDRMLTFNPNKRITVEDALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKER
LKELIFQETARFQPGAPGAP
NT seq 1143 nt   +upstreamnt  +downstreamnt
atggcggcggtggtggctgctgaagggggagggggcggggagccccgaggagttgacggg
accggcccgggggtccccggcaaggtggagatggtgaagggtcagccatttgacgtggga
ccacgctacacagagctgcagtacattggggagggggcgtacggcatggtcagctctgcc
tttgaccatgttcggaagacccgggtagccatcaaaaagatcagcccatttgagcaccag
acatattgccagcgcacccttcgggagattcagatcctgcttcgatgccaccatgaaaat
gtcattggcatccgtgacatccttcgggcacccacgctggaggccatgagagatgtctac
attgttcaggacctgatggaaacagacttgtataagctgttaaagagccagcagctgagt
aatgatcatgtctgctacttcttgtaccaaatcctacggggcctcaaatatattcactca
gccaatgtgctccatcgggacctcaaaccctccaacctgctcattaacaccacttgtgac
ctcaagatctgtgactttggtctggcccggattgctgaccctgagcatgatcacacaggc
ttcctgacagagtatgtggctactcgttggtatagagcaccagagatcatgcttaattcc
aagggctataccaaatccatcgatatctggtctgtgggctgtatcctcgcagaaatgctc
tccaatcggcccatctttcctgggaagcactatctggaccagctgaaccacattctaggt
atcctgggttctccatctcaggatgatctgaactgtatcatcaacatgaaagctcggaac
tacctacagtcccttccatccaagcctaaggtgccctgggtcaagctgtttcccaaggca
gattccaaagccctggacctgctggaccggatgttgacctttaaccccaacaagcgaatc
acagtggaggatgctctggcccatccctacttggagcagtactatgatccaactgatgag
ccagtggcagaagaaccctttacctttgatatggagctggatgaccttccaaaggaacga
ctaaaagaacttatcttccaagagacagcccgattccaacctggggccccaggagccccc
tga

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