KEGG   Gracilinanus agilis (agile gracile opossum): 123234242
Entry
123234242         CDS       T07702                                 
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas00140  Steroid hormone biosynthesis
gas01100  Metabolic pathways
gas04913  Ovarian steroidogenesis
gas04917  Prolactin signaling pathway
gas04927  Cortisol synthesis and secretion
gas04934  Cushing syndrome
Module
gas_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
gas_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
gas_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:gas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    123234242
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    123234242
   04917 Prolactin signaling pathway
    123234242
   04927 Cortisol synthesis and secretion
    123234242
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123234242
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:gas00199]
    123234242
Enzymes [BR:gas01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     123234242
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     123234242
Cytochrome P450 [BR:gas00199]
 Cytochrome P450, animal type
  CYP17 family
   123234242
SSDB
Motif
Pfam: p450 DUF7527
Other DBs
NCBI-GeneID: 123234242
NCBI-ProteinID: XP_044516103
LinkDB
Position
2:complement(613431053..613444267)
AA seq 302 aa
MLVQVEIWGKGLEFCYGKALVKLFPNKDLTLLKDSVTLRNELLKKKLKIQKEKFNIDSVN
NLLDALLKAKLDSDNPLVQEPEITDEHILMTVGDIFGAGVETTSSVIKWCIAYLLHYPQV
KEKIQKEIDQKIGFGRTPVLSDRNQLLYLESTIREVLRIRPVAPLLIPHMAWTDTSIGEY
TIPKGTRIYVNLWSIHHDPTQWNEPERFIPERFLDKNKDQLIIPNASYFPFGSGPRVCIG
EFLARSELFLFLAWILQRFDLEVPEDGELPSLDGLYGVVFQITPFKLKIKLRKGWREAEL
SA
NT seq 909 nt   +upstreamnt  +downstreamnt
atgctggtacaagtggagatttggggaaaaggtttagaattttgttatgggaaagcttta
gtgaagctgttcccgaataaagatctgacactgttaaaagatagcgtcacattacggaat
gagctcctaaagaaaaaactgaaaattcagaaggaaaaattcaacatagattctgtcaac
aacctcctggatgcactgctgaaagccaagttggacagtgataatcctctggtccaggaa
ccagagatcacagatgagcacattctaatgacggtgggggacatctttggagctggtgtg
gagaccaccagcagtgtcatcaagtggtgcattgcctacttgctgcactatccccaggta
aaggagaaaattcagaaggaaattgaccagaaaattggctttggccgaactcctgtgctc
agtgataggaaccagcttctctacctggagtccacgatacgtgaggtactccgtatacgg
ccagtggctcccttactcatcccccacatggcatggactgacaccagcattggagaatac
accatccccaaaggcaccaggatctatgtcaacctgtggtccatccatcatgaccctaca
cagtggaatgagccagaacggtttatcccagaacgattcctggacaagaataaggaccaa
ctcatcattccaaatgccagctactttccctttggaagtggaccccgggtctgtattggg
gagttcttggcccggtcagagttattcctctttctggcctggatcctacagagatttgac
ctggaagttcctgaagatggagaactcccttccttagatgggttgtatggagtagtattt
cagataactcccttcaagttaaagatcaagctgaggaaaggctggagagaggctgaactc
agtgcctag

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