Gracilinanus agilis (agile gracile opossum): 123234969
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Entry
123234969 CDS
T07702
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00140
Steroid hormone biosynthesis
gas01100
Metabolic pathways
gas05215
Prostate cancer
Module
gas_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
123234969 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
123234969 (SRD5A2)
Enzymes [BR:
gas01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
123234969 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
123234969
NCBI-ProteinID:
XP_044516911
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Position
2:225887766..225953505
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AA seq
254 aa
AA seq
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MPTMCLLNPVLAGSALLAVCGLLILLRSRPDAYGKQAERLLPLATRLPARAAWFLQELPS
FVVPIGLLAWQPHPLFGPPGTLLLGLFCGHYFHRTFIYAFLTRGSPFPLTILFHALIFCT
LNGFLQGYYLIYCAEYPDEWFTDVRFTSGILLFFLGMAINIHSDYLLRQLRKPGEISYKI
PQGGLFTYISGANYFGEIVEWIGYAMATWSFPGLAFAFFSSCFLGKRAYHHHRFYLKKFQ
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcccacgatgtgcctattgaacccggtgctggcgggcagcgctctgcttgctgtctgc
gggctgttgatattgctgcgctccagacccgacgcgtacggcaaacaggctgagcgcttg
ttgcccttggccaccaggttgccagcccgcgcagcctggttcctccaggaactcccctct
ttcgtggtgcccattgggctgctcgcttggcaaccccacccgctcttcggcccgccgggg
accttactgcttggcctcttctgtggacattactttcacaggacattcatttatgccttt
ctcaccagaggaagtccctttccactcacaatactttttcatgcccttatcttctgtact
ctgaatggcttcctccaaggatactatttaatttactgtgctgaataccctgatgaatgg
ttcactgatgtccgatttacttcaggtattctcttatttttcttgggaatggcaatcaat
attcacagtgattatttactgcgccaactcagaaaacctggagaaatctcctataagatt
ccacaaggaggattattcacttacatatctggagccaattattttggtgagattgtggaa
tggattggctatgccatggcaacctggtccttcccaggcttagcatttgcctttttctca
tcatgtttccttggaaaacgagcttatcaccatcacaggttctatctcaagaagtttcaa
gactaccctaagtctcggaaagccttgattcctttcatattttaa
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