KEGG   Gracilinanus agilis (agile gracile opossum): 123237154
Entry
123237154         CDS       T07702                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01522  Endocrine resistance
gas04015  Rap1 signaling pathway
gas04020  Calcium signaling pathway
gas04024  cAMP signaling pathway
gas04072  Phospholipase D signaling pathway
gas04081  Hormone signaling
gas04082  Neuroactive ligand signaling
gas04261  Adrenergic signaling in cardiomyocytes
gas04270  Vascular smooth muscle contraction
gas04540  Gap junction
gas04611  Platelet activation
gas04713  Circadian entrainment
gas04714  Thermogenesis
gas04724  Glutamatergic synapse
gas04726  Serotonergic synapse
gas04728  Dopaminergic synapse
gas04730  Long-term depression
gas04750  Inflammatory mediator regulation of TRP channels
gas04911  Insulin secretion
gas04912  GnRH signaling pathway
gas04913  Ovarian steroidogenesis
gas04915  Estrogen signaling pathway
gas04916  Melanogenesis
gas04918  Thyroid hormone synthesis
gas04921  Oxytocin signaling pathway
gas04922  Glucagon signaling pathway
gas04923  Regulation of lipolysis in adipocytes
gas04924  Renin secretion
gas04925  Aldosterone synthesis and secretion
gas04926  Relaxin signaling pathway
gas04927  Cortisol synthesis and secretion
gas04928  Parathyroid hormone synthesis, secretion and action
gas04934  Cushing syndrome
gas04935  Growth hormone synthesis, secretion and action
gas04961  Endocrine and other factor-regulated calcium reabsorption
gas04962  Vasopressin-regulated water reabsorption
gas04970  Salivary secretion
gas04971  Gastric acid secretion
gas04972  Pancreatic secretion
gas04976  Bile secretion
gas05012  Parkinson disease
gas05030  Cocaine addiction
gas05031  Amphetamine addiction
gas05032  Morphine addiction
gas05034  Alcoholism
gas05142  Chagas disease
gas05146  Amoebiasis
gas05163  Human cytomegalovirus infection
gas05165  Human papillomavirus infection
gas05200  Pathways in cancer
gas05207  Chemical carcinogenesis - receptor activation
gas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    123237154 (GNAS)
   04020 Calcium signaling pathway
    123237154 (GNAS)
   04072 Phospholipase D signaling pathway
    123237154 (GNAS)
   04024 cAMP signaling pathway
    123237154 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123237154 (GNAS)
   04081 Hormone signaling
    123237154 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    123237154 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123237154 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    123237154 (GNAS)
   04922 Glucagon signaling pathway
    123237154 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    123237154 (GNAS)
   04912 GnRH signaling pathway
    123237154 (GNAS)
   04913 Ovarian steroidogenesis
    123237154 (GNAS)
   04915 Estrogen signaling pathway
    123237154 (GNAS)
   04921 Oxytocin signaling pathway
    123237154 (GNAS)
   04926 Relaxin signaling pathway
    123237154 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    123237154 (GNAS)
   04918 Thyroid hormone synthesis
    123237154 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    123237154 (GNAS)
   04916 Melanogenesis
    123237154 (GNAS)
   04924 Renin secretion
    123237154 (GNAS)
   04925 Aldosterone synthesis and secretion
    123237154 (GNAS)
   04927 Cortisol synthesis and secretion
    123237154 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123237154 (GNAS)
   04270 Vascular smooth muscle contraction
    123237154 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    123237154 (GNAS)
   04971 Gastric acid secretion
    123237154 (GNAS)
   04972 Pancreatic secretion
    123237154 (GNAS)
   04976 Bile secretion
    123237154 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    123237154 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    123237154 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    123237154 (GNAS)
   04728 Dopaminergic synapse
    123237154 (GNAS)
   04726 Serotonergic synapse
    123237154 (GNAS)
   04730 Long-term depression
    123237154 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123237154 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123237154 (GNAS)
   04714 Thermogenesis
    123237154 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123237154 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    123237154 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    123237154 (GNAS)
   05165 Human papillomavirus infection
    123237154 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123237154 (GNAS)
   05142 Chagas disease
    123237154 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    123237154 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    123237154 (GNAS)
   05031 Amphetamine addiction
    123237154 (GNAS)
   05032 Morphine addiction
    123237154 (GNAS)
   05034 Alcoholism
    123237154 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    123237154 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123237154 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123237154 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gas04147]
    123237154 (GNAS)
   04031 GTP-binding proteins [BR:gas04031]
    123237154 (GNAS)
Exosome [BR:gas04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123237154 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   123237154 (GNAS)
  Exosomal proteins of colorectal cancer cells
   123237154 (GNAS)
  Exosomal proteins of bladder cancer cells
   123237154 (GNAS)
GTP-binding proteins [BR:gas04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    123237154 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc GTP_EFTU TniB AAA_29 PaREP1 AAA_14
Other DBs
NCBI-GeneID: 123237154
NCBI-ProteinID: XP_044519788
LinkDB
Position
2:256182839..256369519
AA seq 379 aa
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQLYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNAEEKKMKIQDIKNNIKEAIETIVTAMGNLAPPVELANPENQFRIDYILNLA
NQIDFDFPPEFYEHTKTLWQDEGVKACYERSNEYQLIDCAQYFLDKIDVVKQNEYTPSDQ
DLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNM
VIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEF
ARYTTPDDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRV
FNDCRDIIQRMHLRQYELL
NT seq 1140 nt   +upstreamnt  +downstreamnt
atggggtgcctggggaacagcaagacggaagatcagcggaacgaggagaaggcacagcga
gaggccaacaagaagatcgaaaagcagctgcagaaggacaagcagctctaccgggccacc
caccgcctcctgctgctgggtgctggtgaatctggtaaaagcacaatagtaaaacagatg
aggatcttgcacgtcaatggatttaatgctgaggagaaaaaaatgaaaatccaagatatt
aaaaataatattaaagaagctatagagacaatagtgacagcaatgggaaatttggcacct
ccagttgagctagccaatccagagaatcagtttcgaattgactacattttaaacttagct
aaccagatagactttgacttcccaccagaattttatgaacataccaaaacactttggcaa
gatgaaggtgtaaaagcctgctacgagagatctaatgaatatcaattgattgattgtgct
caatactttctagacaagattgatgtagtcaaacaaaatgaatatacaccatctgaccaa
gatcttctcagatgcagagtattgacatcaggaatttttgaaaccaaatttcaagtggat
aaagtaaattttcacatgtttgatgtcggaggacaacgagatgaacgtagaaaatggatc
cagtgttttaatgatgtgactgctatcatatttgtggtggccagcagtagctacaacatg
gttattcgagaggacaatcagaccaatcggcttcaagaagcgctaaacctcttcaagagt
atctggaacaacaggtggctacggaccatttcagtaattctattcctgaataaacaggat
ttattagcagagaaagttttggcagggaaatctaaaattgaggactactttccagaattt
gctcgctacaccacaccagatgatgcaacacctgaacctggtgaggatcccagagttaca
agggccaagtattttattagggatgaatttcttagaatcagcacagcaagtggagatgga
aggcactactgctatccccacttcacatgtgcagtggatacagaaaatatcagaagggtt
ttcaatgactgtcgggacattattcaacggatgcaccttcgtcaatatgagttattgtga

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