Gracilinanus agilis (agile gracile opossum): 123237265
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Entry
123237265 CDS
T07702
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00790
Folate biosynthesis
gas01100
Metabolic pathways
gas01240
Biosynthesis of cofactors
gas01523
Antifolate resistance
gas04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
123237265 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
123237265 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123237265 (FPGS)
Enzymes [BR:
gas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
123237265 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
123237265
NCBI-ProteinID:
XP_044520007
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Position
2:complement(285119906..285137386)
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AA seq
589 aa
AA seq
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MSWARCRALHAALRLAAELPLRGCLASRRGLSARPVPQEPGMEYQDAVRTLNTLQTNASF
LEQIKRERGDPQVQLEAMKHYLIRSGLQIEDLDQLKIIHVTGTKGKGSTCAFTERILRGY
GLKTGFYSSPHLVQVRERIRINGEPISPELFTKYFWRLYNQLEETKDGSCVSMPPYFRFL
TILAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTNILGDTIEKIAW
QKGGIFKPGVPAFTVSQPDSPLEVLKERAQQLPCPLYLCPPLDAFEEEEQPLHLGLAGDH
QRSNAALALQLARCWLQQQGHKGIGELKTVRLTSRRALPLAPVFHPTRPMKQGLQDTEWL
GRTQTLRRGALTWYLDGAHTTSSIQAGVRWFRRAVLNQEKPNNGPEVRVLLFNATGERDT
AALLKLLQPCQFDYAVFCPNLTEISPVGNADQQNFTVTLDHMLTRCLENQKQWNRLAEEK
TGLDPWLAQTSESSSGPLHGPLLLVPPAPRPLNTNSLVFSCISHALQWISQGRDPHFQPS
SPPRGLHSHPVAGTGAVLLKEASSIQVLVTGSLHLVGGVLKLLDPTLSQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtcttgggcccgttgccgggcgctgcacgcggccctgcggctcgcagcggagcttccg
ctccggggctgtctggcatccaggcgggggctaagtgcgcgaccggtgccgcaggagccc
gggatggagtaccaggatgctgtgcggaccctcaacacccttcaaaccaatgctagcttc
ctcgagcagatcaagcgagaacgaggagacccacaggtccagttagaagccatgaagcat
tatttaatccgaagtgggctgcagatagaggacttggatcagttgaagatcatccatgta
acagggactaaagggaagggatccacttgtgccttcacagaacgcattctccgtggctat
ggtctgaaaactggattctatagctctcctcacctggtgcaggtacgggagcgaatccgt
attaatggtgaacccatcagccctgagctcttcaccaaatatttctggcgactctacaat
cagctcgaggagactaaggatggcagttgtgtcagcatgcccccttacttccgcttcctt
accatcctggctttccacgtgttccttcaagaaaaggtggacctagcagtagtggaggtg
ggcatcggtggtgcttatgactgtaccaacattatcaggaagccggtggtctgtgggata
tcatctctgggcatagaccataccaacatcctaggtgacactattgagaagattgcatgg
caaaaagggggcatctttaagcctggagtgccagctttcaccgtgtcccagccagactcc
ccgctggaggtactgaaggagcgagctcaacagctcccgtgcccgctctacctgtgccct
ccactggatgcctttgaggaagaagagcagccgctgcacctgggcttggcaggcgatcac
cagcggagcaacgctgctctggctctgcagctggcacgatgctggctccaacaacagggc
cacaagggaattggggagctaaagacagtcaggctgacctctcggcgagccctgcccctc
gctcctgtgttccatcccacccgacccatgaagcaagggctgcaggacacagaatggcta
ggccggacacagacactgagacgaggggccctcacctggtacctggatggggcacacacc
accagcagtattcaggcaggggtgcggtggttccgccgggcagtgctcaaccaagagaag
cctaacaatggcccggaggttcgagttttgctctttaatgctacaggagaacgggacaca
gcggctctgctgaagttgctgcagccttgccagtttgactatgctgtcttctgccccaat
ctgactgagatatctcctgtggggaatgcagaccagcagaactttacagtcaccctagat
catatgctgacacgatgtttggagaaccagaaacagtggaacaggctggcagaggagaag
acaggcctagatccctggctggcccagacctcagaatccagcagcggccccttacatgga
cctctcctcctggtgcctccggctccccgacccctcaacaccaactccctggtctttagc
tgcatctcccatgccctgcagtggatcagccagggccgggatccccacttccagccctcc
agccctccccgggggcttcactcccaccccgtggctggcactggggctgtcctcctcaag
gaagcctcctccatccaggtgctggtcacgggcagccttcacctggtgggtggtgtctta
aagctcctggatcccactttgtcccagtga
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