Gracilinanus agilis (agile gracile opossum): 123238083
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Entry
123238083 CDS
T07702
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas01521
EGFR tyrosine kinase inhibitor resistance
gas01522
Endocrine resistance
gas04010
MAPK signaling pathway
gas04014
Ras signaling pathway
gas04015
Rap1 signaling pathway
gas04066
HIF-1 signaling pathway
gas04068
FoxO signaling pathway
gas04081
Hormone signaling
gas04114
Oocyte meiosis
gas04140
Autophagy - animal
gas04144
Endocytosis
gas04150
mTOR signaling pathway
gas04151
PI3K-Akt signaling pathway
gas04152
AMPK signaling pathway
gas04211
Longevity regulating pathway
gas04213
Longevity regulating pathway - multiple species
gas04510
Focal adhesion
gas04520
Adherens junction
gas04550
Signaling pathways regulating pluripotency of stem cells
gas04730
Long-term depression
gas04913
Ovarian steroidogenesis
gas04914
Progesterone-mediated oocyte maturation
gas05200
Pathways in cancer
gas05202
Transcriptional misregulation in cancer
gas05205
Proteoglycans in cancer
gas05214
Glioma
gas05215
Prostate cancer
gas05218
Melanoma
gas05224
Breast cancer
gas05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123238083 (IGF1R)
04014 Ras signaling pathway
123238083 (IGF1R)
04015 Rap1 signaling pathway
123238083 (IGF1R)
04066 HIF-1 signaling pathway
123238083 (IGF1R)
04068 FoxO signaling pathway
123238083 (IGF1R)
04151 PI3K-Akt signaling pathway
123238083 (IGF1R)
04152 AMPK signaling pathway
123238083 (IGF1R)
04150 mTOR signaling pathway
123238083 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
123238083 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123238083 (IGF1R)
04140 Autophagy - animal
123238083 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
123238083 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123238083 (IGF1R)
04520 Adherens junction
123238083 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
123238083 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
123238083 (IGF1R)
04914 Progesterone-mediated oocyte maturation
123238083 (IGF1R)
09156 Nervous system
04730 Long-term depression
123238083 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
123238083 (IGF1R)
04213 Longevity regulating pathway - multiple species
123238083 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123238083 (IGF1R)
05202 Transcriptional misregulation in cancer
123238083 (IGF1R)
05205 Proteoglycans in cancer
123238083 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123238083 (IGF1R)
05214 Glioma
123238083 (IGF1R)
05218 Melanoma
123238083 (IGF1R)
05215 Prostate cancer
123238083 (IGF1R)
05224 Breast cancer
123238083 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123238083 (IGF1R)
01522 Endocrine resistance
123238083 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gas01001
]
123238083 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
gas04090
]
123238083 (IGF1R)
Enzymes [BR:
gas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123238083 (IGF1R)
Protein kinases [BR:
gas01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
123238083 (IGF1R)
CD molecules [BR:
gas04090
]
Proteins
123238083 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
123238083
NCBI-ProteinID:
XP_044521357
LinkDB
All DBs
Position
2:586859931..587243428
Genome browser
AA seq
1362 aa
AA seq
DB search
MKSGAGRGSPTSLWGLLFLFSTLCLWPTNGEICGPHIDIRNEIQELKRLENCTVIEGYLR
ILLISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGKNLFYNYALVIF
EMTNLKEIGLYNLRNITRGAIRIEKNSELCYLSTVDWSLILDAVSNNYIVGNKNPKECGD
LCPGTMEEKPLCEKTTINNEYSFRCWTTNHCQKMCPSSCGKRACTDQNECCHPECLGSCS
APDNNTACVACRHYYYAGTCVPTCPPNTYKFEGWRCVDKDFCASVLSAETSEFEKFVIHN
DECMQECPSGFIRNGSQSMFCSPCEGPCPKVCEGEKKTKTIDSVTSAQMLQGCTVFKGNL
LINIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRYILGEEQLEGNYSF
YVLDNQNLQQLWDWNLHNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDINTR
NNGERASCESDVLHFISNTTMKNRIKLTWQRYRPPDYRDLISFTVYFKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVKPGILLQGLKPWTQYAIYVKAVTLTMVENDHIRGAKSE
IVYIRTKAAVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKVPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERRRRDVFQIANSTLPSRNRNTTVADHFTNMSDAEEIETEYPFFE
SRVDNKERTLISHLRPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPAEGADNIPGPVL
WEERPDNTVHLKWSEPENPNGLILMYEIKYGQQVEDQRECVSRQEYRKFGGARLTRLNPG
NYSARVQATSLSGNGSWTDPVFFYVPPKNYENFLHLMIALPIAGLFIVGGLLIMWYVFNK
KRNSDRLGNGVLYASVNPEYFSAADVYVPDEWEVPREKITMSRELGQGSFGMVYEGTAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPETENNPCQMLPTLKKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIIGSIKDELDPGFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQPADKHSGH
KAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq
4089 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggcgccggaagagggtccccgacctcactttgggggcttctgtttctcttt
tctacactttgcctttggccaacaaatggagaaatttgtgggccacacattgacattcgc
aatgaaatccaggagttgaagcgactagaaaactgcacagtgattgagggctacctccga
attctactgatctctaaggcagaggactaccggaacttccgttttccaaagctcacggtc
atcaccgactacttgctgctttttcgtgtggcgggcttggagagccttagtgacctcttc
cctaaccttacagtcatccgagggaaaaaccttttttataactatgccttggtgatcttt
gagatgacgaatctcaaagagatcgggctgtataaccttaggaacatcactcggggggcc
atcaggattgagaagaattcagaactctgttacctctccaccgtggactggtctttgatt
ctggatgctgtatctaacaactatattgtgggaaataaaaacccaaaggagtgtggggac
ctttgtccagggacaatggaagagaagccattgtgtgaaaagacgaccattaataatgag
tacagcttccgctgctggaccacaaaccactgtcagaaaatgtgtcctagctcatgtgga
aagcgggcttgcacagaccagaatgaatgctgccaccccgagtgcttgggaagctgtagt
gcacccgacaacaacacagcctgcgtggcttgccgccattactactacgcaggcacttgt
gtgcccacgtgccctcctaacacttacaagtttgagggttggcggtgtgtggacaaagac
ttctgtgccagcgtcctcagtgctgaaaccagtgaatttgaaaagtttgtgatccacaat
gatgagtgcatgcaggagtgtccctctgggttcatacggaatgggagccaaagtatgttc
tgcagcccctgtgaaggcccttgccccaaagtctgtgagggggaaaagaagacaaagaca
attgattctgtaacttcagcacaaatgctgcagggatgcactgtcttcaaaggcaatttg
ctcattaatatccggcgaggcaataacatagcctctgaactggagaatttcatgggcctg
attgagactgttacaggatatgtgaagattcgccattcacatgccttagtctctctgtct
ttcttgaaaaatctacggtatattttaggagaagaacagctggaagggaattactctttc
tacgtccttgataaccagaatttacagcagttatgggactggaacctccataatctgaca
atcaaagaagggaaaatgtattttgcttttaatcccaaattgtgtgtttctgaaatttat
cgaatggaagaagtgtcaggaactaaaggtcgccagagcaaaggagacataaacactagg
aacaatggagaaagagcctcttgtgaaagtgacgttttgcatttcatttccaacactaca
atgaagaaccggattaagctaacatggcaacggtatcgtcctcctgattacagggatctt
attagctttactgtttacttcaaagaggcaccattcaagaatgtcactgagtatgacggg
caagatgcgtgtggctctaatagctggaatatggttgatgtggatctccctccgaataaa
gatgtcaaacctggaattttactgcagggattgaaaccttggactcagtatgctatctac
gtcaaagcagttactctcacaatggtggagaatgaccacatccggggagcaaaaagtgaa
attgtgtatattcgtaccaaagctgcagttccttctattcccttggatgttatttcagca
tctaattcatcctcccagctcattgtgaagtggaatcctccttccctcccaaacggtaac
ttgtcttactacatagtaagatggcagcgacagcctcaagatagttacctctaccgacac
aattactgctccaaagacaaagtccctattagaaaatatgctgatgggaccattgatgtt
gaagaggttactgaaaatcctaaaaccgaagtctgcggtggggagaaaggaccttgctgc
gcttgtcccaagaccgaggccgagaagcaggcagaaaaagaggaggccgagtacagaaaa
gtctttgagaattttctgcacaattctatctttgtacccagacctgaacggaggcggagg
gacgtcttccaaattgccaattctacgttgcccagtcggaacaggaacactacagtggca
gatcacttcaccaacatgtcagacgcagaagagattgaaacagaatatccgttctttgag
agcagagtggataataaagagaggactttaatttctcatctcaggccttttactctgtac
cgaattgatattcatagttgcaaccatgaagcggatactcttggctgcagcgcttctaac
tttgtctttgcaaggaccatgcccgcagaaggggcagataatattcctgggccagtgcta
tgggaagaaagaccagataatactgtccacttgaagtggtcagaacctgaaaatcccaat
ggactgatattaatgtatgaaataaagtatggtcagcaagtagaggatcagcgggaatgt
gtttccagacaagaatacaggaaatttggaggggccaggcttacacggctaaaccctggg
aactattcagcccgtgttcaggccacctctctttctgggaatggatcatggactgaccct
gtattcttctatgtcccacccaaaaattatgaaaacttccttcacttaatgatcgctctc
cctatcgcaggattatttatagttggaggattgctgataatgtggtatgtcttcaataaa
aaaagaaacagtgacagattagggaatggagttctatatgcatctgtcaatccagagtac
ttcagtgctgcagatgtgtatgttccagatgaatgggaggtacctcgagagaagatcacc
atgagtcgagaacttgggcagggttcatttgggatggtatatgagggaactgctaaagga
gtggtgaaagatgagcctgaaaccagggtagccatcaaaacagtcaatgaggcagcaagc
atgcgagagagaattgaatttctcaatgaagcttcagtaatgaaagaattcaattgtcat
catgtggttcggttgctcggtgtagtgtcccagggccagccaacgttggtcatcatggaa
ttgatgacaagaggggatctcaaaagttatctcagatctctgaggccagagacagagaat
aatccatgccagatgcttccaaccttaaagaagatgattcagatggctggagagattgct
gatggcatggcatatctcaatgccaacaagtttgtccacagggatcttgctgcaaggaat
tgcatggttgccgaagatttcacagtcaaaatcggagattttggtatgacaagagatatc
tatgaaacagattactaccgaaaaggaggtaaaggattattacccgttcgatggatgtct
ccagagtcacttaaggatggagtcttcacaacccattctgatgtttggtcctttggtgtt
gtcctctgggagattgcaacattagcagagcagccctatcagggcatgtctaatgaacaa
gttctccggtttgttatggagggtggccttctagagaaaccagacaactgccccgatatg
ctgtttgaattgatgcgtatgtgttggcagtacaatcccaaaatgagaccttctttcctg
gagatcatcggcagcatcaaagatgagctggacccaggcttcaaggaggtctccttcttc
tacagtgaagagaataagcctccagacaccgaagagctggacctagagactgagaacatg
gagagcattcccttagacccttcctccaccctccagccggctgacaaacactcaggacat
aaagccgagaatgggcctggtgtggtggtcctcagggccagctttgatgaaaggcagcct
tacgcgcacatgaatgggggacgcaagaacgaaagggccttacctttgccccagtcttcg
gcctgctga
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integrated database retrieval system
