Gracilinanus agilis (agile gracile opossum): 123240288
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Entry
123240288 CDS
T07702
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00562
Inositol phosphate metabolism
gas01100
Metabolic pathways
gas01521
EGFR tyrosine kinase inhibitor resistance
gas01522
Endocrine resistance
gas01524
Platinum drug resistance
gas04012
ErbB signaling pathway
gas04014
Ras signaling pathway
gas04015
Rap1 signaling pathway
gas04024
cAMP signaling pathway
gas04062
Chemokine signaling pathway
gas04066
HIF-1 signaling pathway
gas04068
FoxO signaling pathway
gas04070
Phosphatidylinositol signaling system
gas04071
Sphingolipid signaling pathway
gas04072
Phospholipase D signaling pathway
gas04081
Hormone signaling
gas04140
Autophagy - animal
gas04150
mTOR signaling pathway
gas04151
PI3K-Akt signaling pathway
gas04152
AMPK signaling pathway
gas04210
Apoptosis
gas04211
Longevity regulating pathway
gas04213
Longevity regulating pathway - multiple species
gas04218
Cellular senescence
gas04360
Axon guidance
gas04370
VEGF signaling pathway
gas04380
Osteoclast differentiation
gas04510
Focal adhesion
gas04550
Signaling pathways regulating pluripotency of stem cells
gas04611
Platelet activation
gas04613
Neutrophil extracellular trap formation
gas04620
Toll-like receptor signaling pathway
gas04625
C-type lectin receptor signaling pathway
gas04630
JAK-STAT signaling pathway
gas04650
Natural killer cell mediated cytotoxicity
gas04660
T cell receptor signaling pathway
gas04662
B cell receptor signaling pathway
gas04664
Fc epsilon RI signaling pathway
gas04666
Fc gamma R-mediated phagocytosis
gas04668
TNF signaling pathway
gas04670
Leukocyte transendothelial migration
gas04722
Neurotrophin signaling pathway
gas04725
Cholinergic synapse
gas04750
Inflammatory mediator regulation of TRP channels
gas04810
Regulation of actin cytoskeleton
gas04910
Insulin signaling pathway
gas04914
Progesterone-mediated oocyte maturation
gas04915
Estrogen signaling pathway
gas04917
Prolactin signaling pathway
gas04919
Thyroid hormone signaling pathway
gas04923
Regulation of lipolysis in adipocytes
gas04926
Relaxin signaling pathway
gas04929
GnRH secretion
gas04930
Type II diabetes mellitus
gas04931
Insulin resistance
gas04932
Non-alcoholic fatty liver disease
gas04933
AGE-RAGE signaling pathway in diabetic complications
gas04935
Growth hormone synthesis, secretion and action
gas04960
Aldosterone-regulated sodium reabsorption
gas04973
Carbohydrate digestion and absorption
gas05010
Alzheimer disease
gas05017
Spinocerebellar ataxia
gas05020
Prion disease
gas05100
Bacterial invasion of epithelial cells
gas05132
Salmonella infection
gas05135
Yersinia infection
gas05142
Chagas disease
gas05146
Amoebiasis
gas05160
Hepatitis C
gas05161
Hepatitis B
gas05162
Measles
gas05163
Human cytomegalovirus infection
gas05164
Influenza A
gas05165
Human papillomavirus infection
gas05166
Human T-cell leukemia virus 1 infection
gas05167
Kaposi sarcoma-associated herpesvirus infection
gas05168
Herpes simplex virus 1 infection
gas05169
Epstein-Barr virus infection
gas05170
Human immunodeficiency virus 1 infection
gas05171
Coronavirus disease - COVID-19
gas05200
Pathways in cancer
gas05203
Viral carcinogenesis
gas05205
Proteoglycans in cancer
gas05206
MicroRNAs in cancer
gas05207
Chemical carcinogenesis - receptor activation
gas05208
Chemical carcinogenesis - reactive oxygen species
gas05210
Colorectal cancer
gas05211
Renal cell carcinoma
gas05212
Pancreatic cancer
gas05213
Endometrial cancer
gas05214
Glioma
gas05215
Prostate cancer
gas05218
Melanoma
gas05220
Chronic myeloid leukemia
gas05221
Acute myeloid leukemia
gas05222
Small cell lung cancer
gas05223
Non-small cell lung cancer
gas05224
Breast cancer
gas05225
Hepatocellular carcinoma
gas05226
Gastric cancer
gas05230
Central carbon metabolism in cancer
gas05231
Choline metabolism in cancer
gas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05415
Diabetic cardiomyopathy
gas05417
Lipid and atherosclerosis
gas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123240288 (PIK3CD)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123240288 (PIK3CD)
04014 Ras signaling pathway
123240288 (PIK3CD)
04015 Rap1 signaling pathway
123240288 (PIK3CD)
04370 VEGF signaling pathway
123240288 (PIK3CD)
04630 JAK-STAT signaling pathway
123240288 (PIK3CD)
04668 TNF signaling pathway
123240288 (PIK3CD)
04066 HIF-1 signaling pathway
123240288 (PIK3CD)
04068 FoxO signaling pathway
123240288 (PIK3CD)
04070 Phosphatidylinositol signaling system
123240288 (PIK3CD)
04072 Phospholipase D signaling pathway
123240288 (PIK3CD)
04071 Sphingolipid signaling pathway
123240288 (PIK3CD)
04024 cAMP signaling pathway
123240288 (PIK3CD)
04151 PI3K-Akt signaling pathway
123240288 (PIK3CD)
04152 AMPK signaling pathway
123240288 (PIK3CD)
04150 mTOR signaling pathway
123240288 (PIK3CD)
09133 Signaling molecules and interaction
04081 Hormone signaling
123240288 (PIK3CD)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123240288 (PIK3CD)
09143 Cell growth and death
04210 Apoptosis
123240288 (PIK3CD)
04218 Cellular senescence
123240288 (PIK3CD)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123240288 (PIK3CD)
04550 Signaling pathways regulating pluripotency of stem cells
123240288 (PIK3CD)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123240288 (PIK3CD)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123240288 (PIK3CD)
04613 Neutrophil extracellular trap formation
123240288 (PIK3CD)
04620 Toll-like receptor signaling pathway
123240288 (PIK3CD)
04625 C-type lectin receptor signaling pathway
123240288 (PIK3CD)
04650 Natural killer cell mediated cytotoxicity
123240288 (PIK3CD)
04660 T cell receptor signaling pathway
123240288 (PIK3CD)
04662 B cell receptor signaling pathway
123240288 (PIK3CD)
04664 Fc epsilon RI signaling pathway
123240288 (PIK3CD)
04666 Fc gamma R-mediated phagocytosis
123240288 (PIK3CD)
04670 Leukocyte transendothelial migration
123240288 (PIK3CD)
04062 Chemokine signaling pathway
123240288 (PIK3CD)
09152 Endocrine system
04910 Insulin signaling pathway
123240288 (PIK3CD)
04923 Regulation of lipolysis in adipocytes
123240288 (PIK3CD)
04929 GnRH secretion
123240288 (PIK3CD)
04915 Estrogen signaling pathway
123240288 (PIK3CD)
04914 Progesterone-mediated oocyte maturation
123240288 (PIK3CD)
04917 Prolactin signaling pathway
123240288 (PIK3CD)
04926 Relaxin signaling pathway
123240288 (PIK3CD)
04935 Growth hormone synthesis, secretion and action
123240288 (PIK3CD)
04919 Thyroid hormone signaling pathway
123240288 (PIK3CD)
09154 Digestive system
04973 Carbohydrate digestion and absorption
123240288 (PIK3CD)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
123240288 (PIK3CD)
09156 Nervous system
04725 Cholinergic synapse
123240288 (PIK3CD)
04722 Neurotrophin signaling pathway
123240288 (PIK3CD)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123240288 (PIK3CD)
09158 Development and regeneration
04360 Axon guidance
123240288 (PIK3CD)
04380 Osteoclast differentiation
123240288 (PIK3CD)
09149 Aging
04211 Longevity regulating pathway
123240288 (PIK3CD)
04213 Longevity regulating pathway - multiple species
123240288 (PIK3CD)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123240288 (PIK3CD)
05206 MicroRNAs in cancer
123240288 (PIK3CD)
05205 Proteoglycans in cancer
123240288 (PIK3CD)
05207 Chemical carcinogenesis - receptor activation
123240288 (PIK3CD)
05208 Chemical carcinogenesis - reactive oxygen species
123240288 (PIK3CD)
05203 Viral carcinogenesis
123240288 (PIK3CD)
05230 Central carbon metabolism in cancer
123240288 (PIK3CD)
05231 Choline metabolism in cancer
123240288 (PIK3CD)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123240288 (PIK3CD)
09162 Cancer: specific types
05210 Colorectal cancer
123240288 (PIK3CD)
05212 Pancreatic cancer
123240288 (PIK3CD)
05225 Hepatocellular carcinoma
123240288 (PIK3CD)
05226 Gastric cancer
123240288 (PIK3CD)
05214 Glioma
123240288 (PIK3CD)
05221 Acute myeloid leukemia
123240288 (PIK3CD)
05220 Chronic myeloid leukemia
123240288 (PIK3CD)
05218 Melanoma
123240288 (PIK3CD)
05211 Renal cell carcinoma
123240288 (PIK3CD)
05215 Prostate cancer
123240288 (PIK3CD)
05213 Endometrial cancer
123240288 (PIK3CD)
05224 Breast cancer
123240288 (PIK3CD)
05222 Small cell lung cancer
123240288 (PIK3CD)
05223 Non-small cell lung cancer
123240288 (PIK3CD)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123240288 (PIK3CD)
05170 Human immunodeficiency virus 1 infection
123240288 (PIK3CD)
05161 Hepatitis B
123240288 (PIK3CD)
05160 Hepatitis C
123240288 (PIK3CD)
05171 Coronavirus disease - COVID-19
123240288 (PIK3CD)
05164 Influenza A
123240288 (PIK3CD)
05162 Measles
123240288 (PIK3CD)
05168 Herpes simplex virus 1 infection
123240288 (PIK3CD)
05163 Human cytomegalovirus infection
123240288 (PIK3CD)
05167 Kaposi sarcoma-associated herpesvirus infection
123240288 (PIK3CD)
05169 Epstein-Barr virus infection
123240288 (PIK3CD)
05165 Human papillomavirus infection
123240288 (PIK3CD)
09171 Infectious disease: bacterial
05132 Salmonella infection
123240288 (PIK3CD)
05135 Yersinia infection
123240288 (PIK3CD)
05100 Bacterial invasion of epithelial cells
123240288 (PIK3CD)
09174 Infectious disease: parasitic
05146 Amoebiasis
123240288 (PIK3CD)
05142 Chagas disease
123240288 (PIK3CD)
09164 Neurodegenerative disease
05010 Alzheimer disease
123240288 (PIK3CD)
05017 Spinocerebellar ataxia
123240288 (PIK3CD)
05020 Prion disease
123240288 (PIK3CD)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123240288 (PIK3CD)
05418 Fluid shear stress and atherosclerosis
123240288 (PIK3CD)
05415 Diabetic cardiomyopathy
123240288 (PIK3CD)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123240288 (PIK3CD)
04932 Non-alcoholic fatty liver disease
123240288 (PIK3CD)
04931 Insulin resistance
123240288 (PIK3CD)
04933 AGE-RAGE signaling pathway in diabetic complications
123240288 (PIK3CD)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123240288 (PIK3CD)
01524 Platinum drug resistance
123240288 (PIK3CD)
01522 Endocrine resistance
123240288 (PIK3CD)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gas04131
]
123240288 (PIK3CD)
Enzymes [BR:
gas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
123240288 (PIK3CD)
Membrane trafficking [BR:
gas04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
123240288 (PIK3CD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_p85B
PI3K_rbd
PI3K_C2
Motif
Other DBs
NCBI-GeneID:
123240288
NCBI-ProteinID:
XP_044523653
LinkDB
All DBs
Position
3:44590828..44612403
Genome browser
AA seq
1046 aa
AA seq
DB search
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSSRGWGA
GTLRAPTRTLFVNVKFEGNEESFTFQASPNDFPLALMACALKKRATVFRQSGLERPEDYT
LQVNGKYEYLYGNHPLFQFQYICACLHKGLTPHLTMVHSSSILAMRDEQSNPPAQAPKLR
AKPPPIPVKKPSSVSLWSLEQPFCVELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPPLEKILELGKNGEHARVTEDEQQQLREILERKVAAELYEHEKDLVWKMRREIQE
QFPEALARLLLVTKWNRHEDVAQMLFLLRSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSNHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAGGGADSHVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
NT seq
3141 nt
NT seq
+upstream
nt +downstream
nt
atgccccctggagtcgactgtcctatggaattctggtccaaggaagaaaaccagagcgtg
gtggtggatttcttgctgcctacaggggtttatttgaacttccccgtctctcgaaatgcc
aacctcagcaccatcaagcaggtcctctggcaccatgcccagtacgagcccctgttccac
atgctcagcgaccccgaggcctacgtcttcacctgcatcaaccagacggccgagcagcaa
gagctggaggacgagcagcggcgcctgtgcgacatccagcccttcctgccggtgctgcgg
ctcgtggcccgccagggggaccgtgtgaagaagctcatcaactcgcagatcagcctcctc
atcggcaaagggctacacgaattcgactctctgcgggatcccgaagtcaacgacttccgc
gccaagatgcgccagttctgcgaggaggccgcggcccaccggcagcagctgggctgggag
gcctggatgcactacaacttccccctccagctggagccctcgtcccgcggctggggggcc
ggcacgctgcgggcgcccaccaggactctctttgtcaacgtcaagttcgagggcaatgag
gagagcttcaccttccaggcgtcccccaacgactttcccctggcgctgatggcctgcgcg
ctcaagaagagggccaccgtgttccggcagtcggggctggagcggcccgaggactacacg
ctgcaggtgaacggcaagtacgagtacctgtacgggaaccaccccctgttccagttccag
tacatctgcgcctgcctgcacaagggcctgaccccccacctcaccatggtccactcgtcc
tccatcctggccatgcgcgacgagcagagcaaccccccggcccaggcccccaagctgcgg
gccaagccgccccccatccccgtgaagaagccctcctccgtgtctctctggtccctggag
cagcccttctgcgtggagctggtgcagggcagcaaggtgaacgccgacgagaggatgaag
ctcgtggtgctggccggcctcttccatgggaatgaaatgctgtgcaagacggtgtccagc
tccgaggtgaccgtgtgctcggagcccgtgtggaagcagcggctcgagttcgacatcaac
gtgtgcgacctgccccgcatggcccggctctgcttcgccctctacgccgtcatcgagaag
gccaagaaggcccgctccaccaagaagaagtccaagaaggccgactgccccatcgcctgg
gccaacctcatgctgtttgactacaaggaccagctgaagaccggcgagtgctgcctgtac
atgtggtcctccgtcccggatgagaagggggagctgctgaaccccatgggcaccgtgcgg
agtaaccccaacaccgagagcgccgcggccctcgtcatctgcatccccgaagtggctccc
caccccgtgtactaccctcctctggagaagattttggagctgggcaagaacggagagcac
gcgcgagtcaccgaggacgagcagcagcagcttcgcgagatcctggagcgcaaggtggcg
gcggagctgtacgagcacgagaaggacctggtgtggaagatgcgccgagagatccaggag
cagttccccgaggccctggccaggctcctgctcgtcaccaagtggaaccggcacgaggac
gtggcccagatgctcttcctgctgcgctcctggccggagctgcccgtgctcagcgcgctc
gagctgctggacttcagcttccccgaccgccacgtgggctcctttgccatccagtccttg
aggaagctgacggacgacgagctcttccagtacctcctgcagctggtgcaggtgctcaag
tacgagtcctacctggactgcgagttgaccaagttcctgctggaccgggccctggccaac
cgcaagatcggccacttcctcttctggcacctgcgctccgagatgcacgtcccctccgtg
gctctgcgcttcggcctcatcatggaggcctattgccggggcagcaaccaccacatgaag
gtgttgatgaagcagggggaggcactgaacaaaatgaaggcactgaatgactttgtcaaa
gtgagctcccagaagaccaccaagccgcagaccaaggagctgatgcatgtgtgtatgagg
caggagacctacttagaggccctctcgaacgtgcaatctcccctgaaccccagtacctta
ctgtctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagccgctgtgg
atcgtgtacagcaacgaggaggccggcgggggcgccgacagccacgtgggcatcatcttc
aagaacggcgacgacctgcgccaggacatgctcaccctgcagatgatccagctcatggac
gtgctgtggaagcaggaggggctggacctgcggatgactccctacgggtgcctctcgacg
ggcgaccggacgggcctcatcgaggtcgtgtcccactcggacaccatcgccaacatccag
ctcaacaaaagcaacatggctgccacagccgcgttcaataaggacgcgctgctcaactgg
ctcaagtccaagaacccgggggaggctctggagcgagccatcgaggagttcacgctgtcc
tgcgcgggctactgcgtggccacctacgtgctgggcatcggcgaccggcacagcgacaac
atcatgatccgcgagagcgggcagctcttccacatcgattttggccatttcttggggaac
ttcaagaccaaatttggaatcaaccgtgagcgagtgccgttcatcctcacctacgacttt
gtgcacgtcatccagcaggggaagaccaacaacaacgagaagtttgagaggttccggagt
tactgcgagagggcgtacaccatcctgcgccgccacgggctcctcttcctccatctcttc
gcactgatgcgggcagccggcctgcccgaactcagctgctccaaagacatccagtatctc
aaggattccctggccttgggtaaaaccgacgaagaggccctgaagcacttccgggtgaag
tttaacgaagcccttcgggaaagctggaaaaccaaagtgaactggttggcccacaatgtg
tccaaagacaacagacagtag
DBGET
integrated database retrieval system