Gracilinanus agilis (agile gracile opossum): 123242454
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Entry
123242454 CDS
T07702
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00230
Purine metabolism
gas00670
One carbon pool by folate
gas01100
Metabolic pathways
gas01523
Antifolate resistance
Module
gas_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123242454 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
123242454 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123242454 (GART)
Enzymes [BR:
gas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
123242454 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
123242454 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
123242454 (GART)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_5
DUF3104
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
123242454
NCBI-ProteinID:
XP_044526149
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All DBs
Position
3:complement(409408478..409445072)
Genome browser
AA seq
1011 aa
AA seq
DB search
MAVCVLVIGNGGREHTLAWKLAQSQHVRHVIVAPGNAGTANNEKISNSAVSVTDYTLLAQ
FCKDQKIELVVVGPEAPLAAGIVGNLTSAGVKCFGPTAEAAQLESSKKFAKEFMDRHGIP
TAKWKAFTTPEEACNFVMSADFPALVIKASGLAAGKGVIVASNKEEACKAIKEIMQDKAF
GAAGDTVVIEEVLEGEEVSCLCFTDGKTVALMPPAQDHKRLLDGDHGPNTGGMGAYCPTP
QVSKDLLLEIKNTILQRAVDGMQQEGIPYIGILYAGIMLTKSGPKVLEFNCRFGDPECQV
ILPLLKSDFYEIIQSILDGQLSNSLPVWLEDSTAVTVVMASKGYPANYIKGIEITGIPEA
KALGLEVFQAGTALKEDKIVTNGGRVLTVTAVQRDLMSALEEANKGIAVIKFEGAIYRKD
IGYRAISFLKQPRGLTYKESGVDIAAGNELVKKIKPLAKATSRPGCNVDLGGFAGLFDLK
AAGYKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDINTAKTIVAGIAKACEEAGCALLGGETAEMPGVYPPGEYDLAGFAVGAMERDQKLP
QLDRITEGDVIIGIASSGVHSNGFSLVRKIVENSSVQFSSLVPDGCGNQTLGELLLNPTK
IYSRTLLPILRSGHVKAFAHITGGGLLENIPRVLPDKLGVDLDARCWKIPRIFSWLQHEG
HLSEEEMAKTFNCGIGAVMVVQKDLAEQVLKDIHQHKEEAWIIGNVVTCPTGCSRVKVKH
LIQTMQINGSVSLVNESLKDCFGVQPKRARVAVLISGTGTNLQSLIDSTREPTSFAQIII
VISNKDGVAGLEKAENAGIPTKVINHKLYKSRPEFDNEIDRVLEEFSIDLICLAGFMRIL
SRPFVQKWSGKILNIHPSLLPSFKGSNAHEQVLESGVRITGCTVHFVAEEVDAGQIIAQE
AVPVMRGDTIGTLSERVKIAEHKIFPAALQLVASGAVRLGGNGKICWTKEE
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggcagtttgcgtgcttgtgattggcaatgggggaagggaacataccctggcttggaaa
cttgctcagtctcaacatgttagacatgtgatagttgccccaggaaatgcaggaacggcc
aacaatgagaaaatttcaaattcagctgtgtcagtcactgattatactttgcttgctcag
ttctgcaaagatcagaagattgaacttgtagtcgttggaccagaggctcctcttgctgct
ggaattgttgggaacctgacatctgcaggagtgaaatgttttggacccacagcagaggca
gctcagttagagtccagcaaaaaatttgccaaagagtttatggacagacatggaatccct
actgcaaagtggaaggctttcaccacacctgaagaagcctgcaactttgtcatgagtgca
gactttcctgctctagttataaaggccagtggtctggctgctggaaaaggtgtaattgtg
gctagtaacaaagaagaggcttgcaaagcaattaaagagataatgcaggataaagctttt
ggagctgctggtgatactgttgtaattgaagaagttcttgaaggagaagaggtgtcttgt
ttgtgtttcactgatggtaagactgtggcccttatgccaccagcccaggaccataagcga
ttattggatggagaccatggccccaatacgggaggaatgggagcttattgtccaacacca
caggtaagtaaagatttgttattggaaattaaaaataccattcttcagagagcagtagat
ggcatgcagcaagaaggcattccatatataggaatattgtatgctggtataatgcttacc
aagagtggcccaaaagttctggagtttaattgcagatttggagatccagaatgccaggta
attcttccacttcttaaaagtgatttttatgaaataatccaatcaattttagatggtcag
ctttctaattctctgccagtatggcttgaagatagcactgctgtgaccgttgtcatggca
agtaaaggctatccagcaaactacatcaaaggcatagagataacaggaattcctgaggct
aaagctttaggcctggaggtgtttcaagcaggcacagctctgaaagaggataaaatagta
actaatggtggtagagttcttacagtaacagccgtccagagagatctgatgtctgctctt
gaagaagccaataaaggaatagctgttataaaatttgaaggagctatttatagaaaggac
attggctatagagctatctctttcctaaaacagcccagaggcctgacttacaaggaaagt
ggggtggatattgcagctggcaatgaactagttaagaaaattaaacctttggctaaagct
acctccagaccaggatgtaatgtagatcttggaggatttgctggcctctttgacttgaaa
gcagctggttataaggatccccttcttgcttctggaacagatggagttggaaccaaatta
aaaattgcacagcaatgcaataagcatgatactattggtcaagatttggttgcaatgtgt
gtcaatgatattttggctcaaggagcagagcctctcttcttcctagattatttttcctgt
gggaaacttgatattaacacagctaaaactatcgttgccggtatagccaaagcatgtgaa
gaagcaggatgtgctcttttgggaggtgaaacggctgaaatgccaggtgtgtatccacct
ggagaatatgaccttgcaggttttgctgttggtgccatggagcgggatcaaaagctccct
caactggacagaatcactgagggcgatgttatcattggaatagcctcttctggagttcat
agtaatggattcagccttgtaaggaagattgtagaaaattcttctgtccagttctcctct
ttagtacctgatggatgtggtaatcaaactctaggagaattgttgttaaatccaaccaaa
atttatagccgaacattgttgcctattcttcgatcaggacatgttaaggcctttgctcat
attactggaggaggactacttgaaaacatcccaagagttcttccagataagctaggggta
gatttggatgctcgatgctggaagatccctagaatattctcatggcttcagcatgaggga
cacctgtcagaagaggaaatggctaagacattcaattgtggaattggagctgtcatggtg
gtacagaaagatctggctgagcaagttctgaaggatatacaccaacataaggaggaagcc
tggataatcgggaatgtagttacttgtcctacagggtgttcccgagtgaaagttaaacat
ctaattcaaacaatgcaaataaatggatccgtctcattagtgaatgaatctttaaaggat
tgctttggtgtccaaccaaagagagcacgagtggctgttctaatatctggaacaggcaca
aatctccagtccctaatagatagtactcgagaaccaactagctttgcccaaattattatt
gttatctctaataaagatggagtggccgggctagagaaagcagaaaatgctggtattcct
actaaggtaattaatcataaattatataaaagtcgcccagaatttgacaatgaaattgac
agagtccttgaagagttctccattgacctaatctgtcttgcaggattcatgagaattttg
tctcgtcctttcgtccagaagtggagtggtaaaatactcaacatccacccatcattgctc
ccttcctttaagggttcaaatgcccatgagcaggttcttgaatctggggtcagaatcact
ggctgtacagtacattttgtggctgaagaagtggatgctggtcagattattgctcaagag
gcagtcccagtaatgagaggtgacactattggaactttatcagaaagagtaaaaatagca
gaacataaaatatttcctgctgctttacagctggtggccagtggtgcagtaagacttgga
ggaaatggaaagatttgttggactaaagaagaataa
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