Gracilinanus agilis (agile gracile opossum): 123245945
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Entry
123245945 CDS
T07702
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00230
Purine metabolism
gas00670
One carbon pool by folate
gas01100
Metabolic pathways
gas01523
Antifolate resistance
Module
gas_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123245945
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
123245945
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123245945
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gas04147
]
123245945
Enzymes [BR:
gas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
123245945
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
123245945
Exosome [BR:
gas04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
123245945
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
123245945
NCBI-ProteinID:
XP_044530852
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Position
1:788229109..788230887
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AA seq
592 aa
AA seq
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MASRQLALLSVSDKTGLLDFAKNLNSVGLTLVASGGTAKALRDAGLTVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNSPEDQADMARLDFSLIRIVVCNLYPFVKTVASPNVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPGDYEVVYTEMLNSDTKDTTMETRRQLALKAFT
HTAQYDQAISDYFRKEYSKGISQIPLRYGMNPHQKPAQLYTVKPKLPLTVLNGSPGFINL
CDALNAWQLVKELKEALGISAATSFKHVSPAGAAVGVPLSEEEAKVCMVHDLYKSLTPLS
TAYARARGADRMSSFGDFIAVSDVCDVTTAKIISREVSDGIIAPGYEEEALKILSKKKNG
SYCVLQMDPCYKPEEDEIRTLFGLHLSQKRNNGVIDKSLFNNIVTKHKDLPESAIRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANNWWLRHHPRVLSMKFKA
GVKRAEISNAIDQYVTGTIGEDEDLAKWEAMFEEVPKLLTDTEKKEWIDTLKQVAISSDA
FFPFRDNVDRAKRSGVEFIVAPSGSTADQIVIEACDELGITLIHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcttcccgccagctcgccttgcttagtgtctctgacaaaacaggattgttggacttt
gccaaaaatctgaattcagttggtttaacactggttgcttctggagggactgcaaaagct
ctcagagatgctggtctcacagtcagagatgtttctgaactgacaggattcccagaaatg
ttaggaggacgtgtgaaaacactgcatcctgcagtacatgctggaatcttggcacgcaac
tctccagaagatcaagctgacatggccagacttgatttcagtcttataagaattgttgtt
tgtaatctgtatccctttgtgaagaccgtggcttctccaaatgtaactgttgaggaagct
gttgaacaaattgatattggtggagtaaccttactcagagctgctgcaaaaaatcatgct
cgagtgacagtagtgtgtgaaccaggagattatgaagtggtgtataccgaaatgctaaat
tctgatactaaagatactactatggagactagacggcagctagcattaaaggcctttact
catactgctcagtatgatcaagcaatatcagattatttcagaaaggaatatagtaaagga
atatctcagattcctttaagatatggaatgaaccctcaccaaaaacctgcacagttatat
acagtgaagcccaaacttcctcttacagttctgaatggatcccctgggtttataaacctg
tgcgatgccttgaatgcctggcaactggtaaaagaactcaaggaagctttaggtatttca
gcagctacctccttcaagcatgtcagtccagcaggtgctgctgttggagttccacttagt
gaggaagaggctaaagtttgcatggttcatgatctctacaagagccttactcctttgtca
actgcatatgcaagagcaagaggagctgacagaatgtcatcatttggtgattttattgct
gtatctgatgtttgtgatgtcactactgctaaaattatctccagagaggtatctgatggt
attattgcacctggatatgaagaagaagccttgaagattctttctaaaaagaagaatgga
agttactgtgtacttcagatggacccatgttacaaaccagaagaggatgaaattcgtact
ctttttggattacatctaagtcagaagaggaataatggtgttattgacaagtccttattt
aacaatattgttacaaagcataaagatttgcctgaatctgctatcagggatctcatcgta
gctactattgctgtcaaatacacccagtccaattcagtgtgctatgctaagaatggtcag
gtaattggtattggagcaggtcagcaatcccgaatacattgtacacggcttgcaggagat
aaggcaaataattggtggcttagacatcatcctcgagtgctttcaatgaaatttaaagct
ggagtaaagagagcagaaatctctaatgcaattgatcagtatgtgactggcacgattggt
gaggatgaagatttggccaaatgggaagcaatgtttgaggaagttcctaaactgttaact
gatacagaaaagaaggaatggattgatacattgaaacaagtggctatcagttctgatgca
tttttcccttttagggataatgtagacagagctaagagaagtggtgtagagtttattgtg
gccccctcaggttcaactgctgaccagattgtgattgaggcttgtgatgagcttggaatt
acactcattcatacgaatcttcgactatttcatcattga
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