Gracilinanus agilis (agile gracile opossum): 123246200
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Entry
123246200 CDS
T07702
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas04140
Autophagy - animal
gas04141
Protein processing in endoplasmic reticulum
gas04210
Apoptosis
gas04932
Non-alcoholic fatty liver disease
gas05010
Alzheimer disease
gas05012
Parkinson disease
gas05014
Amyotrophic lateral sclerosis
gas05016
Huntington disease
gas05017
Spinocerebellar ataxia
gas05022
Pathways of neurodegeneration - multiple diseases
gas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
123246200 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123246200 (ERN1)
09143 Cell growth and death
04210 Apoptosis
123246200 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123246200 (ERN1)
05012 Parkinson disease
123246200 (ERN1)
05014 Amyotrophic lateral sclerosis
123246200 (ERN1)
05016 Huntington disease
123246200 (ERN1)
05017 Spinocerebellar ataxia
123246200 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
123246200 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123246200 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123246200 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gas01001
]
123246200 (ERN1)
Enzymes [BR:
gas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123246200 (ERN1)
Protein kinases [BR:
gas01001
]
Serine/threonine kinases: Other
IRE family
123246200 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ribonuc_2-5A
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
APH
DUF3974
Peptidase_U4
Motif
Other DBs
NCBI-GeneID:
123246200
NCBI-ProteinID:
XP_044531073
LinkDB
All DBs
Position
4:complement(206690208..206720109)
Genome browser
AA seq
573 aa
AA seq
DB search
MATGPQILEPMENDPIAQGVLKYGSRTPERVCRGLRRQNYFHHHQTLFANEALLFSLSGH
HEIPLSASTTILEKFPHKLPRHPENVIPADSEKSFDEVIKIVDRHTEEPTPTTRQDIEFT
RTPVKTEAAVDSMLKDMATIILCTFLLIGWVAFVITYPMLAICLLLPITAVIVRCFMNGW
MNEWGTFDNRAVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIEL
CAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAYLHSLSIVHRDLKPHNILLSMPNAHGK
IKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVF
YYVISDGNHPFGKSLQRQANILLGAYSLDCLHPEKHEDIVAHELIEKMIAMDPQKRPSAK
HVLKHPFFWGLEKQLQFFQDVSDRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQT
DLRKFRTYKGGSVRDLLRAMRNKKHHYRELPEAVQETLGSIPDDFVRYFTSRFPHLLSHT
YRAMELCGHERLFQPYYFQETTELGPPVTNDGL
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atggccactggacctcagatcctggagcctatggaaaatgacccgatcgctcaaggggtt
ctcaagtatggttctaggaccccagaaagggtctgtaggggtctgagaaggcaaaactat
tttcatcatcatcagacattatttgctaatgaagccctcttgttttctctctcaggacat
catgagatccctctgtctgcttctaccacaatcctggagaaattcccccacaaactgccc
cgacatcctgaaaatgtgatccctgctgattcagagaagagttttgacgaggttatcaaa
atagttgaccggcacacagaagaaccaactcctactactcgtcaagatattgaattcact
cgaacgccagtaaaaacagaggctgcagtggactccatgttgaaggacatggctacaatc
atcctgtgtaccttccttcttattggatgggttgccttcgtcatcacctacccaatgttg
gcaatctgtttgctccttcccatcacagcagtgattgtccggtgcttcatgaatggatgg
atgaatgaatgggggacgtttgacaaccgagctgtggcagtgaagaggatactcccagag
tgcttcagttttgcagaccgggaggtgcagctgcttcgggaatcagacgagcatcccaat
gtgattcgctatttctgcacagagcgagatcgccagttccaatacattgccattgaactg
tgtgcagccactttgcaagagtacgtggaacagaaggactttgcccaccttggcttagaa
cccatcaccttgctgcagcagacaacctcgggtcttgcttaccttcattccctcagcatt
gttcacagagacctgaaaccccacaacatcctcctgtccatgcccaatgcacatggcaag
atcaaggctatgatctctgactttggcctctgcaagaagctggccgtaggaagacacagt
ttcagccgccgctccggggtaccaggtaccgagggatggattgccccagagatgctgagc
gaagattgcaaagagaatccgacttacactgtggacattttctctgcgggctgtgtcttt
tactatgtgatatctgatggcaaccacccatttggcaagtccctgcagcggcaagccaac
attcttcttggtgcctacagccttgactgtttgcacccagagaagcacgaagacatcgtt
gctcatgaactaatagaaaaaatgattgctatggatcctcagaaacggccctcagccaag
catgtgctgaaacacccatttttctggggcttagaaaagcaactgcaattttttcaggat
gtgagtgaccgaatagagaaggaggccctagatggtcccatagtgaagcagttagaaaga
ggagggagagcagtggtcaaaatggactggagggaaaacataactgttccactccagaca
gatcttcgaaaattcagaacctataaagggggttctgtaagagatcttctccgtgctatg
agaaataagaagcaccactaccgggagctccccgaggctgtgcaggagaccctgggctct
atccccgatgattttgtccgttatttcacatcacggttcccccatctcctctcccacacc
taccgagccatggaactgtgtggccacgagagactcttccagccttactatttccaagag
accacagaactgggacccccagtcacaaacgatggtctctga
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