KEGG   Gracilinanus agilis (agile gracile opossum): 123247425
Entry
123247425         CDS       T07702                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01521  EGFR tyrosine kinase inhibitor resistance
gas01522  Endocrine resistance
gas01524  Platinum drug resistance
gas04010  MAPK signaling pathway
gas04012  ErbB signaling pathway
gas04014  Ras signaling pathway
gas04015  Rap1 signaling pathway
gas04022  cGMP-PKG signaling pathway
gas04024  cAMP signaling pathway
gas04062  Chemokine signaling pathway
gas04066  HIF-1 signaling pathway
gas04068  FoxO signaling pathway
gas04071  Sphingolipid signaling pathway
gas04072  Phospholipase D signaling pathway
gas04140  Autophagy - animal
gas04150  mTOR signaling pathway
gas04151  PI3K-Akt signaling pathway
gas04152  AMPK signaling pathway
gas04210  Apoptosis
gas04211  Longevity regulating pathway
gas04213  Longevity regulating pathway - multiple species
gas04218  Cellular senescence
gas04261  Adrenergic signaling in cardiomyocytes
gas04370  VEGF signaling pathway
gas04371  Apelin signaling pathway
gas04380  Osteoclast differentiation
gas04510  Focal adhesion
gas04550  Signaling pathways regulating pluripotency of stem cells
gas04611  Platelet activation
gas04613  Neutrophil extracellular trap formation
gas04620  Toll-like receptor signaling pathway
gas04625  C-type lectin receptor signaling pathway
gas04630  JAK-STAT signaling pathway
gas04660  T cell receptor signaling pathway
gas04662  B cell receptor signaling pathway
gas04664  Fc epsilon RI signaling pathway
gas04666  Fc gamma R-mediated phagocytosis
gas04668  TNF signaling pathway
gas04722  Neurotrophin signaling pathway
gas04725  Cholinergic synapse
gas04728  Dopaminergic synapse
gas04810  Regulation of actin cytoskeleton
gas04910  Insulin signaling pathway
gas04914  Progesterone-mediated oocyte maturation
gas04915  Estrogen signaling pathway
gas04917  Prolactin signaling pathway
gas04919  Thyroid hormone signaling pathway
gas04920  Adipocytokine signaling pathway
gas04922  Glucagon signaling pathway
gas04923  Regulation of lipolysis in adipocytes
gas04926  Relaxin signaling pathway
gas04929  GnRH secretion
gas04931  Insulin resistance
gas04932  Non-alcoholic fatty liver disease
gas04933  AGE-RAGE signaling pathway in diabetic complications
gas04935  Growth hormone synthesis, secretion and action
gas04936  Alcoholic liver disease
gas04973  Carbohydrate digestion and absorption
gas05010  Alzheimer disease
gas05017  Spinocerebellar ataxia
gas05132  Salmonella infection
gas05135  Yersinia infection
gas05142  Chagas disease
gas05145  Toxoplasmosis
gas05152  Tuberculosis
gas05160  Hepatitis C
gas05161  Hepatitis B
gas05162  Measles
gas05163  Human cytomegalovirus infection
gas05164  Influenza A
gas05165  Human papillomavirus infection
gas05166  Human T-cell leukemia virus 1 infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05168  Herpes simplex virus 1 infection
gas05169  Epstein-Barr virus infection
gas05170  Human immunodeficiency virus 1 infection
gas05200  Pathways in cancer
gas05205  Proteoglycans in cancer
gas05207  Chemical carcinogenesis - receptor activation
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05210  Colorectal cancer
gas05211  Renal cell carcinoma
gas05212  Pancreatic cancer
gas05213  Endometrial cancer
gas05214  Glioma
gas05215  Prostate cancer
gas05218  Melanoma
gas05220  Chronic myeloid leukemia
gas05221  Acute myeloid leukemia
gas05222  Small cell lung cancer
gas05223  Non-small cell lung cancer
gas05224  Breast cancer
gas05225  Hepatocellular carcinoma
gas05226  Gastric cancer
gas05230  Central carbon metabolism in cancer
gas05231  Choline metabolism in cancer
gas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05415  Diabetic cardiomyopathy
gas05417  Lipid and atherosclerosis
gas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123247425 (AKT3)
   04012 ErbB signaling pathway
    123247425 (AKT3)
   04014 Ras signaling pathway
    123247425 (AKT3)
   04015 Rap1 signaling pathway
    123247425 (AKT3)
   04370 VEGF signaling pathway
    123247425 (AKT3)
   04371 Apelin signaling pathway
    123247425 (AKT3)
   04630 JAK-STAT signaling pathway
    123247425 (AKT3)
   04668 TNF signaling pathway
    123247425 (AKT3)
   04066 HIF-1 signaling pathway
    123247425 (AKT3)
   04068 FoxO signaling pathway
    123247425 (AKT3)
   04072 Phospholipase D signaling pathway
    123247425 (AKT3)
   04071 Sphingolipid signaling pathway
    123247425 (AKT3)
   04024 cAMP signaling pathway
    123247425 (AKT3)
   04022 cGMP-PKG signaling pathway
    123247425 (AKT3)
   04151 PI3K-Akt signaling pathway
    123247425 (AKT3)
   04152 AMPK signaling pathway
    123247425 (AKT3)
   04150 mTOR signaling pathway
    123247425 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123247425 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    123247425 (AKT3)
   04218 Cellular senescence
    123247425 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123247425 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    123247425 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123247425 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123247425 (AKT3)
   04613 Neutrophil extracellular trap formation
    123247425 (AKT3)
   04620 Toll-like receptor signaling pathway
    123247425 (AKT3)
   04625 C-type lectin receptor signaling pathway
    123247425 (AKT3)
   04660 T cell receptor signaling pathway
    123247425 (AKT3)
   04662 B cell receptor signaling pathway
    123247425 (AKT3)
   04664 Fc epsilon RI signaling pathway
    123247425 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    123247425 (AKT3)
   04062 Chemokine signaling pathway
    123247425 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123247425 (AKT3)
   04922 Glucagon signaling pathway
    123247425 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    123247425 (AKT3)
   04920 Adipocytokine signaling pathway
    123247425 (AKT3)
   04929 GnRH secretion
    123247425 (AKT3)
   04915 Estrogen signaling pathway
    123247425 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    123247425 (AKT3)
   04917 Prolactin signaling pathway
    123247425 (AKT3)
   04926 Relaxin signaling pathway
    123247425 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    123247425 (AKT3)
   04919 Thyroid hormone signaling pathway
    123247425 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123247425 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    123247425 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    123247425 (AKT3)
   04728 Dopaminergic synapse
    123247425 (AKT3)
   04722 Neurotrophin signaling pathway
    123247425 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123247425 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    123247425 (AKT3)
   04213 Longevity regulating pathway - multiple species
    123247425 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123247425 (AKT3)
   05205 Proteoglycans in cancer
    123247425 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    123247425 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    123247425 (AKT3)
   05230 Central carbon metabolism in cancer
    123247425 (AKT3)
   05231 Choline metabolism in cancer
    123247425 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123247425 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123247425 (AKT3)
   05212 Pancreatic cancer
    123247425 (AKT3)
   05225 Hepatocellular carcinoma
    123247425 (AKT3)
   05226 Gastric cancer
    123247425 (AKT3)
   05214 Glioma
    123247425 (AKT3)
   05221 Acute myeloid leukemia
    123247425 (AKT3)
   05220 Chronic myeloid leukemia
    123247425 (AKT3)
   05218 Melanoma
    123247425 (AKT3)
   05211 Renal cell carcinoma
    123247425 (AKT3)
   05215 Prostate cancer
    123247425 (AKT3)
   05213 Endometrial cancer
    123247425 (AKT3)
   05224 Breast cancer
    123247425 (AKT3)
   05222 Small cell lung cancer
    123247425 (AKT3)
   05223 Non-small cell lung cancer
    123247425 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123247425 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    123247425 (AKT3)
   05161 Hepatitis B
    123247425 (AKT3)
   05160 Hepatitis C
    123247425 (AKT3)
   05164 Influenza A
    123247425 (AKT3)
   05162 Measles
    123247425 (AKT3)
   05168 Herpes simplex virus 1 infection
    123247425 (AKT3)
   05163 Human cytomegalovirus infection
    123247425 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123247425 (AKT3)
   05169 Epstein-Barr virus infection
    123247425 (AKT3)
   05165 Human papillomavirus infection
    123247425 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123247425 (AKT3)
   05135 Yersinia infection
    123247425 (AKT3)
   05152 Tuberculosis
    123247425 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123247425 (AKT3)
   05142 Chagas disease
    123247425 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123247425 (AKT3)
   05017 Spinocerebellar ataxia
    123247425 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123247425 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    123247425 (AKT3)
   05415 Diabetic cardiomyopathy
    123247425 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123247425 (AKT3)
   04932 Non-alcoholic fatty liver disease
    123247425 (AKT3)
   04931 Insulin resistance
    123247425 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123247425 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123247425 (AKT3)
   01524 Platinum drug resistance
    123247425 (AKT3)
   01522 Endocrine resistance
    123247425 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123247425 (AKT3)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     123247425 (AKT3)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   123247425 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like PH FTA2 ABC1
Other DBs
NCBI-GeneID: 123247425
NCBI-ProteinID: XP_044532250
LinkDB
Position
4:141764195..141944731
AA seq 418 aa
MKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSP
TSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKK
EVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRER
VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAA
TMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME
DIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFVGVNWQDVYDKKLVPP
FKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 1257 nt   +upstreamnt  +downstreamnt
atgaaaacagaacgaccaaagccaaacacatttattatcagatgcctccagtggacaact
gttatagaacgaacatttcatgtggatactccagaggaaagggaagaatggacagaagct
atccaggctgtagcagacagacttcagaggcaagaagaggaaaggatgaactgtagtcca
acttcacaaattgacaatataggagaagaggaaatggatgcttctacaactcatcataaa
agaaagacaatgaatgattttgactatttgaaactattgggtaaaggcacttttgggaaa
gtgattttggttcgagagaaagcaagtggaaaatattatgctatgaagattttgaagaaa
gaagtaattattgcaaaggatgaagtggcacacactctaacagaaagcagagtattaaaa
aacactaggcatccttttttaacatccttgaaatattctttccagacaaaagatcgtttg
tgttttgtgatggagtatgttaatggaggagagctgtttttccatttgtcgagagagcgg
gtgttctctgaggaccgcacacgcttctatggtgcagaaattgtctctgctttggactat
ctacattctggaaagattgtgtaccgtgatctcaagttggaaaatttgatgttggataaa
gatggccacataaaaattacagattttggtctttgcaaagaagggattacagatgcagct
acaatgaagacattttgtggtacacctgaataccttgcacctgaggtgttagaagataat
gactatggccgtgcagtggactggtggggtttaggggttgtcatgtatgaaatgatgtgt
gggagattaccattctacaaccaggatcatgagaaactttttgagctaatactaatggag
gacattaaatttcctcgaactctttcttctgatgcaaaatccttactttcaggactctta
ataaaagatccaaataaacgccttggtggaggtccggatgatgcaaaagaaattatgagg
cacagtttctttgttggagtaaattggcaagatgtatatgataaaaagctggtacctcct
tttaaacctcaagtaacgtctgagacagacaccagatattttgatgaagaatttacagct
caaacaattacaataacaccacctgaaaaatatgacgaagatggtatggactgcatggac
aatgagaggcggccacattttccacagttttcctactcagcaagtggacgagaataa

DBGET integrated database retrieval system