KEGG   Gracilinanus agilis (agile gracile opossum): 123247456
Entry
123247456         CDS       T07702                                 
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01521  EGFR tyrosine kinase inhibitor resistance
gas01522  Endocrine resistance
gas03272  Virion - Hepatitis viruses
gas04010  MAPK signaling pathway
gas04012  ErbB signaling pathway
gas04014  Ras signaling pathway
gas04015  Rap1 signaling pathway
gas04020  Calcium signaling pathway
gas04066  HIF-1 signaling pathway
gas04068  FoxO signaling pathway
gas04072  Phospholipase D signaling pathway
gas04144  Endocytosis
gas04151  PI3K-Akt signaling pathway
gas04510  Focal adhesion
gas04520  Adherens junction
gas04540  Gap junction
gas04630  JAK-STAT signaling pathway
gas04810  Regulation of actin cytoskeleton
gas04912  GnRH signaling pathway
gas04915  Estrogen signaling pathway
gas04921  Oxytocin signaling pathway
gas04926  Relaxin signaling pathway
gas04928  Parathyroid hormone synthesis, secretion and action
gas04934  Cushing syndrome
gas05160  Hepatitis C
gas05163  Human cytomegalovirus infection
gas05165  Human papillomavirus infection
gas05171  Coronavirus disease - COVID-19
gas05200  Pathways in cancer
gas05205  Proteoglycans in cancer
gas05206  MicroRNAs in cancer
gas05207  Chemical carcinogenesis - receptor activation
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05210  Colorectal cancer
gas05212  Pancreatic cancer
gas05213  Endometrial cancer
gas05214  Glioma
gas05215  Prostate cancer
gas05218  Melanoma
gas05219  Bladder cancer
gas05223  Non-small cell lung cancer
gas05224  Breast cancer
gas05225  Hepatocellular carcinoma
gas05226  Gastric cancer
gas05230  Central carbon metabolism in cancer
gas05231  Choline metabolism in cancer
gas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:gas00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    123247456 (EGFR)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123247456 (EGFR)
   04012 ErbB signaling pathway
    123247456 (EGFR)
   04014 Ras signaling pathway
    123247456 (EGFR)
   04015 Rap1 signaling pathway
    123247456 (EGFR)
   04630 JAK-STAT signaling pathway
    123247456 (EGFR)
   04066 HIF-1 signaling pathway
    123247456 (EGFR)
   04068 FoxO signaling pathway
    123247456 (EGFR)
   04020 Calcium signaling pathway
    123247456 (EGFR)
   04072 Phospholipase D signaling pathway
    123247456 (EGFR)
   04151 PI3K-Akt signaling pathway
    123247456 (EGFR)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    123247456 (EGFR)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123247456 (EGFR)
   04520 Adherens junction
    123247456 (EGFR)
   04540 Gap junction
    123247456 (EGFR)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123247456 (EGFR)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    123247456 (EGFR)
   04915 Estrogen signaling pathway
    123247456 (EGFR)
   04921 Oxytocin signaling pathway
    123247456 (EGFR)
   04926 Relaxin signaling pathway
    123247456 (EGFR)
   04928 Parathyroid hormone synthesis, secretion and action
    123247456 (EGFR)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123247456 (EGFR)
   05206 MicroRNAs in cancer
    123247456 (EGFR)
   05205 Proteoglycans in cancer
    123247456 (EGFR)
   05207 Chemical carcinogenesis - receptor activation
    123247456 (EGFR)
   05208 Chemical carcinogenesis - reactive oxygen species
    123247456 (EGFR)
   05230 Central carbon metabolism in cancer
    123247456 (EGFR)
   05231 Choline metabolism in cancer
    123247456 (EGFR)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123247456 (EGFR)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123247456 (EGFR)
   05212 Pancreatic cancer
    123247456 (EGFR)
   05225 Hepatocellular carcinoma
    123247456 (EGFR)
   05226 Gastric cancer
    123247456 (EGFR)
   05214 Glioma
    123247456 (EGFR)
   05218 Melanoma
    123247456 (EGFR)
   05219 Bladder cancer
    123247456 (EGFR)
   05215 Prostate cancer
    123247456 (EGFR)
   05213 Endometrial cancer
    123247456 (EGFR)
   05224 Breast cancer
    123247456 (EGFR)
   05223 Non-small cell lung cancer
    123247456 (EGFR)
  09172 Infectious disease: viral
   05160 Hepatitis C
    123247456 (EGFR)
   05171 Coronavirus disease - COVID-19
    123247456 (EGFR)
   05163 Human cytomegalovirus infection
    123247456 (EGFR)
   05165 Human papillomavirus infection
    123247456 (EGFR)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123247456 (EGFR)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123247456 (EGFR)
   01522 Endocrine resistance
    123247456 (EGFR)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123247456 (EGFR)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gas04147]
    123247456 (EGFR)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     123247456 (EGFR)
Protein kinases [BR:gas01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   123247456 (EGFR)
Exosome [BR:gas04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   123247456 (EGFR)
  Exosomal proteins of pancreatic cancer cells
   123247456 (EGFR)
  Exosomal proteins of bladder cancer cells
   123247456 (EGFR)
SSDB
Motif
Pfam: Recep_L_domain PK_Tyr_Ser-Thr Furin-like GF_recep_IV Pkinase
Other DBs
NCBI-GeneID: 123247456
NCBI-ProteinID: XP_044532293
LinkDB
Position
1:complement(70199953..70265585)
AA seq 840 aa
MFNNCEVVLGNLEITYVQKNYDLSFLKTIQEVAGYVLIALNAVEKIPLENLQVIRGNVLY
ENFYALSVLSNYDANKTGVRELPMKNLLEILIGGVRFNNNPSLCNMETIQWKDIVNSAYF
NNITIDNNSHPKSCEKCDSSCPNGSCWGPGPQYCQTLTKTICAQQCSGRCRGSSPSDCCH
NQCAAGCTGPRESDCLVCRKFRDEATCKDNCPSLLQYNPTTYQMDVNPDGKYSFGATCVR
KCPHNYVVTDHGSCVRSCNADTYEVEEDGVRKCKKCEGPCSKVCNGIGIGELKDVLSINA
TNIKQFQNCTIISGDLHILPVAFKGDSFTNTPPLDPKELNILRTVKEISGFLLIQSWPEN
MTDLHAFEHLEIIRGRTKQHGQFSLAVVDVNITSLGLRSLKEISDGDVIISKNRRLCYAN
TINWTKLFGTKSQKAKITNNKDEKECRVLGHVCHELCSSDGCWGPKPSHCLSCRHVSRHK
KCVEKCNILEGLSCCFLSNYPKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSK
PYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMAR
DPQRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLIPQQGFFNSPSTSRTP
LLSSLSATSNNSATVCIDRNGQTCPVKEESFIQRYSSDPTTVLTEDNADDSFQPVPEYIN
QSAPKNPTGSAIQNPVYHNQPLNPDASKDSLYQNSHNNSAVDNPEYLNTTQPNSVKKAFD
SNSCWNPTAKHPINLDNPDYQQDFFPQEAKPNGVFKVPAAENPEYLRVAAQQSEFIQASA
NT seq 2523 nt   +upstreamnt  +downstreamnt
atgttcaataactgtgaggtggtacttggaaatttagaaattacctacgtccaaaaaaat
tatgacctttccttcctcaagaccatccaggaggttgctggctatgtgcttattgcactc
aatgccgtagagaaaatccctttggaaaatctgcaagtcatcagaggaaatgtgttgtat
gaaaacttttatgctctttctgtgctctccaactatgatgcgaataaaaccggagtgagg
gaactgcccatgaagaatctactagaaatccttatcggtggtgttcggttcaacaataac
ccatctttgtgtaatatggagacgatccagtggaaggatattgtgaactctgcttacttc
aacaacataaccatagacaataacagccatccaaagagttgtgaaaagtgtgattctagt
tgtcccaatgggagctgttggggtcctgggccacagtattgccagactttgacaaaaacc
atctgtgcccagcaatgctcaggacggtgtcgaggtagttcccccagtgactgttgtcac
aaccagtgtgcagcgggttgtactggaccccgagagagtgactgcttggtctgccgaaag
tttcgagatgaagccacgtgcaaagacaattgcccctctctcctgcaatacaacccaacc
acataccagatggacgtcaacccagatggcaaatacagctttggagctacctgtgttcgc
aaatgcccacataactatgtggtgacagatcacggttcctgtgttcgttcctgtaatgct
gatacctatgaagtggaagaagatggcgtccgaaaatgtaaaaaatgtgaaggtccatgt
agtaaagtttgcaatggaataggaatcggtgaactgaaagatgttctctccatcaatgca
acaaacatcaaacaattccagaactgtaccataatcagcggtgatctgcatatcttgccc
gttgcatttaaaggggattccttcaccaatactccacctctggatcccaaagaactgaat
attctcagaaccgtaaaggaaatatcaggatttttgctgattcagtcttggcctgaaaac
atgactgacctccatgcttttgaacatctggaaattatacgaggcagaacaaagcagcat
ggccagttttctcttgctgttgttgatgtgaacataacttccttgggcttacgctccctt
aaggaaatcagtgatggtgatgtcatcatttccaaaaacagaagactctgctatgcaaac
acaataaactggaccaagttgtttggaacaaaaagtcagaaagccaaaatcaccaacaac
aaagatgaaaaagagtgccgtgttctgggtcatgtctgtcatgagttatgctcatctgat
ggctgctggggtccaaagccaagccactgcttgtcctgtcgccatgtgagtcgtcacaag
aaatgtgttgagaaatgcaacattctggaaggattgtcttgttgttttctttctaactat
cccaaggtgcctattaaatggatggctttggaatcgattttacaccgtatttatacccac
caaagcgatgtctggagctatggtgtcaccgtgtgggaactgatgacatttgggtctaag
ccttacgatgggatccctgcaagtgaaatttcatctatactagagaaaggggagcgcctt
cctcagccacccatctgcaccattgatgtctacatgatcatggtcaaatgctggatgata
gatgctgatagtcgccccaagtttcgtgagttaatcatagaattctctaaaatggcccgt
gatccccaacgctaccttgttatacagggagatgagagaatgcacttaccaagccccaca
gactccaaattttatcgcaccctaatggaagaggaggacatggaagatatcgtcgatgcc
gatgagtaccttatcccacagcaaggattcttcaatagtccttccacatctcggactcct
ctcctaagctctctgagtgctaccagcaataattctgccacagtatgcattgatagaaac
gggcagacttgtcccgtgaaggaagaaagcttcatccagagatacagctctgatcccacg
actgtcttaactgaagacaatgcggatgacagcttccagcctgtaccagaatatataaac
cagtcggctccaaaaaaccccacaggctctgccatccagaaccccgtttatcacaaccag
cctttaaatccagatgcctctaaagactctctgtaccaaaattcacacaacaacagcgca
gtggacaaccctgagtatctcaacacgactcagcccaactcggtcaaaaaggcattcgac
agcaattcatgctggaaccccacagccaagcaccccatcaatctggacaacccggactac
cagcaggacttcttcccccaggaagccaagccaaatggggtgtttaaagtcccggctgcg
gaaaatcctgagtacctcagggtagcagcccaacaaagcgaattcattcaagcttcggca
tga

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